Allosteric effects on substrate dissociation from cytochrome P450 3A4 in nanodiscs observed by ensemble and single-molecule fluorescence spectroscopy

Journal of the American Chemical Society

Volumn 130, Issue 47, 2008, Pages 15746-15747

  Nath, Abhinav ^a   Koo, Peter K ^b   Rhoades, Elizabeth ^b   Atkins, William M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; NANODISC;

ALLOSTERISM; ARTICLE; BILAYER MEMBRANE; FLUORESCENCE SPECTROSCOPY; KINETICS; STEADY STATE; THERMODYNAMICS;

ALLOSTERIC REGULATION; CYTOCHROME P-450 CYP3A; HUMANS; NANOSTRUCTURES; OXAZINES; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY;

EID: 56749165088     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja805772r     Document Type: Article

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