-
1
-
-
35148846824
-
Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia
-
Al-Ghnaniem, R., Peters, J., Foresti, R., Heaton, N. & Pufulete, M. 2007. Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia. Am J Clin Nutr 86, 1064-1072.
-
(2007)
Am J Clin Nutr
, vol.86
, pp. 1064-1072
-
-
Al-Ghnaniem, R.1
Peters, J.2
Foresti, R.3
Heaton, N.4
Pufulete, M.5
-
2
-
-
0033555953
-
Role of DNA 5-methylcytosine transferase in cell transformation by fos
-
Bakin, A.V. & Curran, T. 1999. Role of DNA 5-methylcytosine transferase in cell transformation by fos. Science 283, 387-390.
-
(1999)
Science
, vol.283
, pp. 387-390
-
-
Bakin, A.V.1
Curran, T.2
-
3
-
-
77950907191
-
The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival
-
Balasubramanian, S., Adhikary, G. & Eckert, R.L. 2010. The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival. Carcinogenesis 31, 496-503.
-
(2010)
Carcinogenesis
, vol.31
, pp. 496-503
-
-
Balasubramanian, S.1
Adhikary, G.2
Eckert, R.L.3
-
4
-
-
34249299791
-
The complex language of chromatin regulation during transcription
-
Berger, S.L. 2007. The complex language of chromatin regulation during transcription. Nature 447, 407-412.
-
(2007)
Nature
, vol.447
, pp. 407-412
-
-
Berger, S.L.1
-
5
-
-
33847032960
-
The mammalian epigenome
-
Bernstein, B.E., Meissner, A. & Lander, E.S. 2007. The mammalian epigenome. Cell 128, 669-681.
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
6
-
-
10744228850
-
Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood
-
Bhargava, S.K., Sachdev, H.S., Fall, C.H., Osmond, C., Lakshmy, R., Barker, D.J., Biswas, S.K., Ramji, S., Prabhakaran, D. & Reddy, K.S. 2004. Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood. N Engl J Med 350, 865-875.
-
(2004)
N Engl J Med
, vol.350
, pp. 865-875
-
-
Bhargava, S.K.1
Sachdev, H.S.2
Fall, C.H.3
Osmond, C.4
Lakshmy, R.5
Barker, D.J.6
Biswas, S.K.7
Ramji, S.8
Prabhakaran, D.9
Reddy, K.S.10
-
7
-
-
75649087405
-
Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction
-
Bouchard, L., Rabasa-Lhoret, R., Faraj, M., Lavoie, M.E., Mill, J., Perusse, L. & Vohl, M.C. 2010. Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction. Am J Clin Nutr 91, 309-320.
-
(2010)
Am J Clin Nutr
, vol.91
, pp. 309-320
-
-
Bouchard, L.1
Rabasa-Lhoret, R.2
Faraj, M.3
Lavoie, M.E.4
Mill, J.5
Perusse, L.6
Vohl, M.C.7
-
8
-
-
72749090135
-
Association between lifestyle factors and CpG island methylation in a cancer-free population
-
Brait, M., Ford, J.G., Papaiahgari, S., Garza, M.A., Lee, J.I., Loyo, M., Maldonado, L., Begum, S., McCaffrey, L., Howerton, M., Sidransky, D., Emerson, M.R., Ahmed, S., Williams, C.D. & Hoque, M.O. 2009. Association between lifestyle factors and CpG island methylation in a cancer-free population. Cancer Epidemiol Biomarkers Prev 18, 2984-2991.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 2984-2991
-
-
Brait, M.1
Ford, J.G.2
Papaiahgari, S.3
Garza, M.A.4
Lee, J.I.5
Loyo, M.6
Maldonado, L.7
Begum, S.8
McCaffrey, L.9
Howerton, M.10
Sidransky, D.11
Emerson, M.R.12
Ahmed, S.13
Williams, C.D.14
Hoque, M.O.15
-
9
-
-
77955627637
-
Nutrition, epigenetics, and developmental plasticity: implications for understanding human disease
-
Burdge, G.C. & Lillycrop, K.A. 2010. Nutrition, epigenetics, and developmental plasticity: implications for understanding human disease. Annu Rev Nutr 30, 315-339.
-
(2010)
Annu Rev Nutr
, vol.30
, pp. 315-339
-
-
Burdge, G.C.1
Lillycrop, K.A.2
-
10
-
-
58349094740
-
Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation
-
Choi, K.C., Jung, M.G., Lee, Y.H., Yoon, J.C., Kwon, S.H., Kang, H.B., Kim, M.J., Cha, J.H., Kim, Y.J., Jun, W.J., Lee, J.M. & Yoon, H.G. 2009. Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation. Cancer Res 69, 583-592.
-
(2009)
Cancer Res
, vol.69
, pp. 583-592
-
-
Choi, K.C.1
Jung, M.G.2
Lee, Y.H.3
Yoon, J.C.4
Kwon, S.H.5
Kang, H.B.6
Kim, M.J.7
Cha, J.H.8
Kim, Y.J.9
Jun, W.J.10
Lee, J.M.11
Yoon, H.G.12
-
11
-
-
70149099610
-
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
-
Christensen, B.C., Houseman, E.A., Marsit, C.J., Zheng, S., Wrensch, M.R., Wiemels, J.L., Nelson, H.H., Karagas, M.R., Padbury, J.F., Bueno, R., Sugarbaker, D.J., Yeh, R.F., Wiencke, J.K. & Kelsey, K.T. 2009. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet 5, e1000602.
-
(2009)
PLoS Genet
, vol.5
-
-
Christensen, B.C.1
Houseman, E.A.2
Marsit, C.J.3
Zheng, S.4
Wrensch, M.R.5
Wiemels, J.L.6
Nelson, H.H.7
Karagas, M.R.8
Padbury, J.F.9
Bueno, R.10
Sugarbaker, D.J.11
Yeh, R.F.12
Wiencke, J.K.13
Kelsey, K.T.14
-
12
-
-
77958130827
-
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism
-
Christensen, K.E., Wu, Q., Wang, X., Deng, L., Caudill, M.A. & Rozen, R. 2010. Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism. J Nutr 140, 1736-1741.
-
(2010)
J Nutr
, vol.140
, pp. 1736-1741
-
-
Christensen, K.E.1
Wu, Q.2
Wang, X.3
Deng, L.4
Caudill, M.A.5
Rozen, R.6
-
13
-
-
0027946745
-
DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation
-
Cravo, M., Fidalgo, P., Pereira, A.D., Gouveia-Oliveira, A., Chaves, P., Selhub, J., Mason, J.B., Mira, F.C. & Leitao, C.N. 1994. DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation. Eur J Cancer Prev 3, 473-479.
-
(1994)
Eur J Cancer Prev
, vol.3
, pp. 473-479
-
-
Cravo, M.1
Fidalgo, P.2
Pereira, A.D.3
Gouveia-Oliveira, A.4
Chaves, P.5
Selhub, J.6
Mason, J.B.7
Mira, F.C.8
Leitao, C.N.9
-
14
-
-
0031775688
-
Effect of folate supplementation on DNA methylation of rectal mucosa in patients with colonic adenomas: correlation with nutrient intake
-
Cravo, M.L., Pinto, A.G., Chaves, P., Cruz, J.A., Lage, P., Nobre Leitao, C. & Costa Mira, F. 1998. Effect of folate supplementation on DNA methylation of rectal mucosa in patients with colonic adenomas: correlation with nutrient intake. Clin Nutr 17, 45-49.
-
(1998)
Clin Nutr
, vol.17
, pp. 45-49
-
-
Cravo, M.L.1
Pinto, A.G.2
Chaves, P.3
Cruz, J.A.4
Lage, P.5
Nobre Leitao, C.6
Costa Mira, F.7
-
15
-
-
66149137211
-
The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factors
-
Danaei, G., Ding, E.L., Mozaffarian, D., Taylor, B., Rehm, J., Murray, C.J. & Ezzati, M. 2009. The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factors. PLoS Med 6, e1000058.
-
(2009)
PLoS Med
, vol.6
-
-
Danaei, G.1
Ding, E.L.2
Mozaffarian, D.3
Taylor, B.4
Rehm, J.5
Murray, C.J.6
Ezzati, M.7
-
16
-
-
0041417403
-
Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats
-
Davis, C.D. & Uthus, E.O. 2003. Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats. J Nutr 133, 2907-2914.
-
(2003)
J Nutr
, vol.133
, pp. 2907-2914
-
-
Davis, C.D.1
Uthus, E.O.2
-
17
-
-
7244221348
-
DNA methylation, cancer susceptibility, and nutrient interactions
-
Davis, C.D. & Uthus, E.O. 2004. DNA methylation, cancer susceptibility, and nutrient interactions. Exp Biol Med (Maywood) 229, 988-995.
-
(2004)
Exp Biol Med (Maywood)
, vol.229
, pp. 988-995
-
-
Davis, C.D.1
Uthus, E.O.2
-
18
-
-
0034533186
-
Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon
-
Davis, C.D., Uthus, E.O. & Finley, J.W. 2000. Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon. J Nutr 130, 2903-2909.
-
(2000)
J Nutr
, vol.130
, pp. 2903-2909
-
-
Davis, C.D.1
Uthus, E.O.2
Finley, J.W.3
-
19
-
-
3242721652
-
Genistein alters methylation patterns in mice
-
Day, J.K., Bauer, A.M., DesBordes, C., Zhuang, Y., Kim, B.E., Newton, L.G., Nehra, V., Forsee, K.M., MacDonald, R.S., Besch-Williford, C., Huang, T.H. & Lubahn, D.B. 2002. Genistein alters methylation patterns in mice. J Nutr 132, 2419S-2423S.
-
(2002)
J Nutr
, vol.132
-
-
Day, J.K.1
Bauer, A.M.2
DesBordes, C.3
Zhuang, Y.4
Kim, B.E.5
Newton, L.G.6
Nehra, V.7
Forsee, K.M.8
MacDonald, R.S.9
Besch-Williford, C.10
Huang, T.H.11
Lubahn, D.B.12
-
20
-
-
50949132079
-
Dietary manipulation of histone structure and function
-
Delage, B. & Dashwood, R.H. 2008. Dietary manipulation of histone structure and function. Annu Rev Nutr 28, 347-366.
-
(2008)
Annu Rev Nutr
, vol.28
, pp. 347-366
-
-
Delage, B.1
Dashwood, R.H.2
-
21
-
-
0035835483
-
Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells
-
Demary, K., Wong, L. & Spanjaard, R.A. 2001. Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells. Cancer Lett 163, 103-107.
-
(2001)
Cancer Lett
, vol.163
, pp. 103-107
-
-
Demary, K.1
Wong, L.2
Spanjaard, R.A.3
-
22
-
-
33645633542
-
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
-
Dolinoy, D.C., Weidman, J.R., Waterland, R.A. & Jirtle, R.L. 2006. Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect 114, 567-572.
-
(2006)
Environ Health Perspect
, vol.114
, pp. 567-572
-
-
Dolinoy, D.C.1
Weidman, J.R.2
Waterland, R.A.3
Jirtle, R.L.4
-
23
-
-
34548715144
-
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
-
Dolinoy, D.C., Huang, D. & Jirtle, R.L. 2007. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc Natl Acad Sci USA 104, 13056-13061.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13056-13061
-
-
Dolinoy, D.C.1
Huang, D.2
Jirtle, R.L.3
-
24
-
-
34548439098
-
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas
-
van den Donk, M., Pellis, L., Crott, J.W., van Engeland, M., Friederich, P., Nagengast, F.M., van Bergeijk, J.D., de Boer, S.Y., Mason, J.B., Kok, F.J., Keijer, J. & Kampman, E. 2007. Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas. J Nutr 137, 2114-2120.
-
(2007)
J Nutr
, vol.137
, pp. 2114-2120
-
-
van den Donk, M.1
Pellis, L.2
Crott, J.W.3
van Engeland, M.4
Friederich, P.5
Nagengast, F.M.6
van Bergeijk, J.D.7
de Boer, S.Y.8
Mason, J.B.9
Kok, F.J.10
Keijer, J.11
Kampman, E.12
-
25
-
-
3242755145
-
Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines
-
Druesne, N., Pagniez, A., Mayeur, C., Thomas, M., Cherbuy, C., Duee, P.H., Martel, P. & Chaumontet, C. 2004. Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines. Carcinogenesis 25, 1227-1236.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1227-1236
-
-
Druesne, N.1
Pagniez, A.2
Mayeur, C.3
Thomas, M.4
Cherbuy, C.5
Duee, P.H.6
Martel, P.7
Chaumontet, C.8
-
26
-
-
0037731713
-
Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer
-
van Engeland, M., Weijenberg, M.P., Roemen, G.M., Brink, M., de Bruine, A.P., Goldbohm, R.A., van den Brandt, P.A., Baylin, S.B., de Goeij, A.F. & Herman, J.G. 2003. Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer. Cancer Res 63, 3133-3137.
-
(2003)
Cancer Res
, vol.63
, pp. 3133-3137
-
-
van Engeland, M.1
Weijenberg, M.P.2
Roemen, G.M.3
Brink, M.4
de Bruine, A.P.5
Goldbohm, R.A.6
van den Brandt, P.A.7
Baylin, S.B.8
de Goeij, A.F.9
Herman, J.G.10
-
27
-
-
33645294070
-
Oncomirs - microRNAs with a role in cancer
-
Esquela-Kerscher, A. & Slack, F.J. 2006. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6, 259-269.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
28
-
-
0345275879
-
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
-
Fang, M.Z., Wang, Y., Ai, N., Hou, Z., Sun, Y., Lu, H., Welsh, W. & Yang, C.S. 2003. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 63, 7563-7570.
-
(2003)
Cancer Res
, vol.63
, pp. 7563-7570
-
-
Fang, M.Z.1
Wang, Y.2
Ai, N.3
Hou, Z.4
Sun, Y.5
Lu, H.6
Welsh, W.7
Yang, C.S.8
-
29
-
-
26444451123
-
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
-
Fang, M.Z., Chen, D., Sun, Y., Jin, Z., Christman, J.K. & Yang, C.S. 2005. Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 11, 7033-7041.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7033-7041
-
-
Fang, M.Z.1
Chen, D.2
Sun, Y.3
Jin, Z.4
Christman, J.K.5
Yang, C.S.6
-
30
-
-
77956913463
-
Personalized epigenomic signatures that are stable over time and covary with body mass index
-
Feinberg, A.P., Irizarry, R.A., Fradin, D., Aryee, M.J., Murakami, P., Aspelund, T., Eiriksdottir, G., Harris, T.B., Launer, L., Gudnason, V. & Fallin, M.D. 2010. Personalized epigenomic signatures that are stable over time and covary with body mass index. Sci Transl Med 2, 49ra67.
-
(2010)
Sci Transl Med
, vol.2
-
-
Feinberg, A.P.1
Irizarry, R.A.2
Fradin, D.3
Aryee, M.J.4
Murakami, P.5
Aspelund, T.6
Eiriksdottir, G.7
Harris, T.B.8
Launer, L.9
Gudnason, V.10
Fallin, M.D.11
-
31
-
-
36249022864
-
-
Foresight Report ., 2nd edn. Government Office for Science, London.
-
Foresight Report 2007. Tackling Obesities: Future Choices - Project Report, 2nd edn. Government Office for Science, London.
-
(2007)
Tackling Obesities: Future Choices - Project Report
-
-
-
32
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga, M.F., Ballestar, E., Paz, M.F., Ropero, S., Setien, F., Ballestar, M.L., Heine-Suner, D., Ciqudosa, J.C., Urioste, M., Benitez, J., Boix-Chornet, M. et al. 2005. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 102, 10604-10609.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
Ropero, S.4
Setien, F.5
Ballestar, M.L.6
Heine-Suner, D.7
Ciqudosa, J.C.8
Urioste, M.9
Benitez, J.10
Boix-Chornet, M.11
-
33
-
-
0037117501
-
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
-
Friso, S., Choi, S.W., Girelli, D., Mason, J.B., Dolnikowski, G.G., Bagley, P.J., Olivieri, O., Jacques, P.F., Rosenberg, I.H., Corrocher, R. & Selhub, J. 2002. A common mutation in the 5, 10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci USA 99, 5606-5611.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5606-5611
-
-
Friso, S.1
Choi, S.W.2
Girelli, D.3
Mason, J.B.4
Dolnikowski, G.G.5
Bagley, P.J.6
Olivieri, O.7
Jacques, P.F.8
Rosenberg, I.H.9
Corrocher, R.10
Selhub, J.11
-
34
-
-
67349190274
-
Sexual dimorphism in environmental epigenetic programming
-
Gabory, A., Attig, L. & Junien, C. 2009. Sexual dimorphism in environmental epigenetic programming. Mol Cell Endocrinol 304, 8-18.
-
(2009)
Mol Cell Endocrinol
, vol.304
, pp. 8-18
-
-
Gabory, A.1
Attig, L.2
Junien, C.3
-
35
-
-
46449087037
-
Effect of in utero and early-life conditions on adult health and disease
-
Gluckman, P.D., Hanson, M.A., Cooper, C. & Thornburg, K.L. 2008. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med 359, 61-73.
-
(2008)
N Engl J Med
, vol.359
, pp. 61-73
-
-
Gluckman, P.D.1
Hanson, M.A.2
Cooper, C.3
Thornburg, K.L.4
-
36
-
-
33847047461
-
Epigenetics: a landscape takes shape
-
Goldberg, A.D., Allis, C.D. & Bernstein, E. 2007. Epigenetics: a landscape takes shape. Cell 128, 635-638.
-
(2007)
Cell
, vol.128
, pp. 635-638
-
-
Goldberg, A.D.1
Allis, C.D.2
Bernstein, E.3
-
37
-
-
38549150275
-
miRBase: tools for microRNA genomics
-
Griffiths-Jones, S., Saini, H.K., van Dongen, S. & Enright, A.J. 2008. miRBase: tools for microRNA genomics. Nucleic Acids Res 36, D154-D158.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Griffiths-Jones, S.1
Saini, H.K.2
van Dongen, S.3
Enright, A.J.4
-
38
-
-
52949108784
-
Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice
-
Guerrero-Bosagna, C.M., Sabat, P., Valdovinos, F.S., Valladares, L.E. & Clark, S.J. 2008. Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC Physiol 8, 17.
-
(2008)
BMC Physiol
, vol.8
, pp. 17
-
-
Guerrero-Bosagna, C.M.1
Sabat, P.2
Valdovinos, F.S.3
Valladares, L.E.4
Clark, S.J.5
-
39
-
-
0029048919
-
Inhibition of AP-1 binding and transcription by gold and selenium involving conserved cysteine residues in Jun and Fos
-
Handel, M.L., Watts, C.K., deFazio, A., Day, R.O. & Sutherland, R.L. 1995. Inhibition of AP-1 binding and transcription by gold and selenium involving conserved cysteine residues in Jun and Fos. Proc Natl Acad Sci USA 92, 4497-4501.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4497-4501
-
-
Handel, M.L.1
Watts, C.K.2
deFazio, A.3
Day, R.O.4
Sutherland, R.L.5
-
40
-
-
0027745794
-
Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro
-
Hass, B.S., Hart, R.W., Lu, M.H. & Lyn-Cook, B.D. 1993. Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro. Mutat Res 295, 281-289.
-
(1993)
Mutat Res
, vol.295
, pp. 281-289
-
-
Hass, B.S.1
Hart, R.W.2
Lu, M.H.3
Lyn-Cook, B.D.4
-
41
-
-
55949137722
-
Persistent epigenetic differences associated with prenatal exposure to famine in humans
-
Heijmans, B.T., Tobi, E.W., Stein, A.D., Putter, H., Blauw, G.J., Susser, E.S., Slagboom, P.E. & Lumey, L.H. 2008. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA 105, 17046-17049.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17046-17049
-
-
Heijmans, B.T.1
Tobi, E.W.2
Stein, A.D.3
Putter, H.4
Blauw, G.J.5
Susser, E.S.6
Slagboom, P.E.7
Lumey, L.H.8
-
42
-
-
0016439429
-
DNA modification mechanisms and gene activity during development
-
Holliday, R. & Pugh, J.E. 1975. DNA modification mechanisms and gene activity during development. Science 187, 226-232.
-
(1975)
Science
, vol.187
, pp. 226-232
-
-
Holliday, R.1
Pugh, J.E.2
-
43
-
-
77950636044
-
Effects of treatment in women with gestational diabetes mellitus: systematic review and meta-analysis
-
Horvath, K., Koch, K., Jeitler, K., Matyas, E., Bender, R., Bastian, H., Lange, S. & Siebenhofer, A. 2010. Effects of treatment in women with gestational diabetes mellitus: systematic review and meta-analysis. BMJ 340, c1395.
-
(2010)
BMJ
, vol.340
-
-
Horvath, K.1
Koch, K.2
Jeitler, K.3
Matyas, E.4
Bender, R.5
Bastian, H.6
Lange, S.7
Siebenhofer, A.8
-
44
-
-
71049186870
-
Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms
-
Hughes, L.A., Van den Brandt, P.A., de Bruine, A.P., Wouters, K.A., Hulsmans, S., Spiertz, A., Goldbohm, R.A., de Goeij, A.F., Herman, J.G., Weijenberg, M.P. & van Engeland, M. 2009. Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms. PLoS ONE 4, e7951.
-
(2009)
PLoS ONE
, vol.4
-
-
Hughes, L.A.1
Van den Brandt, P.A.2
de Bruine, A.P.3
Wouters, K.A.4
Hulsmans, S.5
Spiertz, A.6
Goldbohm, R.A.7
de Goeij, A.F.8
Herman, J.G.9
Weijenberg, M.P.10
van Engeland, M.11
-
45
-
-
0026744196
-
Identification of an estrogen response element in the 3'-flanking region of the murine c-fos protooncogene
-
Hyder, S.M., Stancel, G.M., Nawaz, Z., McDonnell, D.P. & Loose-Mitchell, D.S. 1992. Identification of an estrogen response element in the 3'-flanking region of the murine c-fos protooncogene. J Biol Chem 267, 18047-18054.
-
(1992)
J Biol Chem
, vol.267
, pp. 18047-18054
-
-
Hyder, S.M.1
Stancel, G.M.2
Nawaz, Z.3
McDonnell, D.P.4
Loose-Mitchell, D.S.5
-
46
-
-
38949212693
-
A novel CpG island set identifies tissue-specific methylation at developmental gene loci
-
Illingworth, R., Kerr, A., Desousa, D., Jorgensen, H., Ellis, P., Stalker, J., Jackson, D., Clee, C., Plumb, R., Rogers, J., Humphray, S., Cox, T., Langford, C. & Bird, A. 2008. A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol 6, e22.
-
(2008)
PLoS Biol
, vol.6
-
-
Illingworth, R.1
Kerr, A.2
Desousa, D.3
Jorgensen, H.4
Ellis, P.5
Stalker, J.6
Jackson, D.7
Clee, C.8
Plumb, R.9
Rogers, J.10
Humphray, S.11
Cox, T.12
Langford, C.13
Bird, A.14
-
47
-
-
59149084538
-
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
-
Irizarry, R.A., Ladd-Acosta, C., Wen, B., Wu, Z., Montano, C., Onyango, P., Cui, H., Gabo, K., Rongione, M., Webster, M., Ji, H., Potash, J.B., Sabunciyan, S. & Feinberg, A.P. 2009. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 41, 178-186.
-
(2009)
Nat Genet
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
Wu, Z.4
Montano, C.5
Onyango, P.6
Cui, H.7
Gabo, K.8
Rongione, M.9
Webster, M.10
Ji, H.11
Potash, J.B.12
Sabunciyan, S.13
Feinberg, A.P.14
-
48
-
-
0031816123
-
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
-
Jacob, R.A., Gretz, D.M., Taylor, P.C., James, S.J., Pogribny, I.P., Miller, B.J., Henning, S.M. & Swendseid, M.E. 1998. Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J Nutr 128, 1204-1212.
-
(1998)
J Nutr
, vol.128
, pp. 1204-1212
-
-
Jacob, R.A.1
Gretz, D.M.2
Taylor, P.C.3
James, S.J.4
Pogribny, I.P.5
Miller, B.J.6
Henning, S.M.7
Swendseid, M.E.8
-
49
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch, R. & Bird, A. 2003. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 33(Suppl.), 245-254.
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
50
-
-
0035839136
-
Translating the histone code
-
Jenuwein, T. & Allis, C.D. 2001. Translating the histone code. Science 293, 1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
51
-
-
39149091066
-
Environment, diet and CpG island methylation: epigenetic signals in gastrointestinal neoplasia
-
Johnson, I.T. & Belshaw, N.J. 2008. Environment, diet and CpG island methylation: epigenetic signals in gastrointestinal neoplasia. Food Chem Toxicol 46, 1346-1359.
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 1346-1359
-
-
Johnson, I.T.1
Belshaw, N.J.2
-
52
-
-
77958093579
-
Stress and the epigenetic landscape: a link to the pathobiology of human diseases?
-
Johnstone, S.E. & Baylin, S.B. 2010. Stress and the epigenetic landscape: a link to the pathobiology of human diseases? Nat Rev Genet 11, 806-812.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 806-812
-
-
Johnstone, S.E.1
Baylin, S.B.2
-
53
-
-
70350046301
-
Rethinking how DNA methylation patterns are maintained
-
Jones, P.A. & Liang, G. 2009. Rethinking how DNA methylation patterns are maintained. Nat Rev Genet 10, 805-811.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 805-811
-
-
Jones, P.A.1
Liang, G.2
-
54
-
-
33745074420
-
Impact of diets and nutrients/drugs on early epigenetic programming
-
Junien, C. 2006. Impact of diets and nutrients/drugs on early epigenetic programming. J Inherit Metab Dis 29, 359-365.
-
(2006)
J Inherit Metab Dis
, vol.29
, pp. 359-365
-
-
Junien, C.1
-
55
-
-
15744370742
-
Curcumin-induced histone hypoacetylation: the role of reactive oxygen species
-
Kang, J., Chen, J., Shi, Y., Jia, J. & Zhang, Y. 2005. Curcumin-induced histone hypoacetylation: the role of reactive oxygen species. Biochem Pharmacol 69, 1205-1213.
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 1205-1213
-
-
Kang, J.1
Chen, J.2
Shi, Y.3
Jia, J.4
Zhang, Y.5
-
56
-
-
33645046361
-
Sodium butyrate up-regulates cathelicidin gene expression via activator protein-1 and histone acetylation at the promoter region in a human lung epithelial cell line, EBC-1
-
Kida, Y., Shimizu, T. & Kuwano, K. 2006. Sodium butyrate up-regulates cathelicidin gene expression via activator protein-1 and histone acetylation at the promoter region in a human lung epithelial cell line, EBC-1. Mol Immunol 43, 1972-1981.
-
(2006)
Mol Immunol
, vol.43
, pp. 1972-1981
-
-
Kida, Y.1
Shimizu, T.2
Kuwano, K.3
-
57
-
-
0031022797
-
Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene
-
Kim, Y.I., Pogribny, I.P., Basnakian, A.G., Miller, J.W., Selhub, J., James, S.J. & Mason, J.B. 1997. Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene. Am J Clin Nutr 65, 46-52.
-
(1997)
Am J Clin Nutr
, vol.65
, pp. 46-52
-
-
Kim, Y.I.1
Pogribny, I.P.2
Basnakian, A.G.3
Miller, J.W.4
Selhub, J.5
James, S.J.6
Mason, J.B.7
-
58
-
-
0035133904
-
Effects of folate supplementation on two provisional molecular markers of colon cancer: a prospective, randomized trial
-
Kim, Y.I., Baik, H.W., Fawaz, K., Knox, T., Lee, Y.M., Norton, R., Libby, E. & Mason, J.B. 2001. Effects of folate supplementation on two provisional molecular markers of colon cancer: a prospective, randomized trial. Am J Gastroenterol 96, 184-195.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 184-195
-
-
Kim, Y.I.1
Baik, H.W.2
Fawaz, K.3
Knox, T.4
Lee, Y.M.5
Norton, R.6
Libby, E.7
Mason, J.B.8
-
59
-
-
58749107929
-
Effect of folate deficiency on placental DNA methylation in hyperhomocysteinemic rats
-
Kim, J.M., Hong, K., Lee, J.H., Lee, S. & Chang, N. 2009. Effect of folate deficiency on placental DNA methylation in hyperhomocysteinemic rats. J Nutr Biochem 20, 172-176.
-
(2009)
J Nutr Biochem
, vol.20
, pp. 172-176
-
-
Kim, J.M.1
Hong, K.2
Lee, J.H.3
Lee, S.4
Chang, N.5
-
60
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides, T. 2007. Chromatin modifications and their function. Cell 128, 693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
61
-
-
35748965898
-
Gestational choline deficiency causes global and Igf2 gene DNA hypermethylation by up-regulation of Dnmt1 expression
-
Kovacheva, V.P., Mellott, T.J., Davison, J.M., Wagner, N., Lopez-Coviella, I., Schnitzler, A.C. & Blusztajn, J.K. 2007. Gestational choline deficiency causes global and Igf2 gene DNA hypermethylation by up-regulation of Dnmt1 expression. J Biol Chem 282, 31777-31788.
-
(2007)
J Biol Chem
, vol.282
, pp. 31777-31788
-
-
Kovacheva, V.P.1
Mellott, T.J.2
Davison, J.M.3
Wagner, N.4
Lopez-Coviella, I.5
Schnitzler, A.C.6
Blusztajn, J.K.7
-
62
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis, S. & Heintz, N. 2009. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324, 929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
63
-
-
25144507259
-
Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
-
Lee, W.J., Shim, J.Y. & Zhu, B.T. 2005. Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol Pharmacol 68, 1018-1030.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1018-1030
-
-
Lee, W.J.1
Shim, J.Y.2
Zhu, B.T.3
-
64
-
-
20444411948
-
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
-
Lillycrop, K.A., Phillips, E.S., Jackson, A.A., Hanson, M.A. & Burdge, G.C. 2005. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr 135, 1382-1386.
-
(2005)
J Nutr
, vol.135
, pp. 1382-1386
-
-
Lillycrop, K.A.1
Phillips, E.S.2
Jackson, A.A.3
Hanson, M.A.4
Burdge, G.C.5
-
65
-
-
50049108528
-
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring
-
Lillycrop, K.A., Phillips, E.S., Torrens, C., Hanson, M.A., Jackson, A.A. & Burdge, G.C. 2008. Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr 100, 278-282.
-
(2008)
Br J Nutr
, vol.100
, pp. 278-282
-
-
Lillycrop, K.A.1
Phillips, E.S.2
Torrens, C.3
Hanson, M.A.4
Jackson, A.A.5
Burdge, G.C.6
-
66
-
-
14044255703
-
Oxidative stress is involved in inhibition of copper on histone acetylation in cells
-
Lin, C., Kang, J. & Zheng, R. 2005. Oxidative stress is involved in inhibition of copper on histone acetylation in cells. Chem Biol Interact 151, 167-176.
-
(2005)
Chem Biol Interact
, vol.151
, pp. 167-176
-
-
Lin, C.1
Kang, J.2
Zheng, R.3
-
67
-
-
78049429911
-
Cancer chemoprevention by dietary polyphenols: promising role for epigenetics
-
Link, A., Balaguer, F. & Goel, A. 2010. Cancer chemoprevention by dietary polyphenols: promising role for epigenetics. Biochem Pharmacol 80, 1771-1792.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 1771-1792
-
-
Link, A.1
Balaguer, F.2
Goel, A.3
-
68
-
-
77649240380
-
Widespread and tissue specific age-related DNA methylation changes in mice
-
Maegawa, S., Hinkal, G., Kim, H.S., Shen, L., Zhang, L., Zhang, J., Zhang, N., Liang, S., Donehower, L.A. & Issa, J.P. 2010. Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res 20, 332-340.
-
(2010)
Genome Res
, vol.20
, pp. 332-340
-
-
Maegawa, S.1
Hinkal, G.2
Kim, H.S.3
Shen, L.4
Zhang, L.5
Zhang, J.6
Zhang, N.7
Liang, S.8
Donehower, L.A.9
Issa, J.P.10
-
69
-
-
77949678340
-
Chromatin structure and the inheritance of epigenetic information
-
Margueron, R. & Reinberg, D. 2010. Chromatin structure and the inheritance of epigenetic information. Nat Rev Genet 11, 285-296.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 285-296
-
-
Margueron, R.1
Reinberg, D.2
-
70
-
-
0036980916
-
Pulses and carcinogenesis: potential for the prevention of colon, breast and other cancers
-
Mathers, J.C. 2002. Pulses and carcinogenesis: potential for the prevention of colon, breast and other cancers. Br J Nutr 88(Suppl. 3), S273-S279.
-
(2002)
Br J Nutr
, vol.88
, Issue.SUPPL. 3
-
-
Mathers, J.C.1
-
71
-
-
33646132748
-
Nutritional modulation of ageing: genomic and epigenetic approaches
-
Mathers, J.C. 2006. Nutritional modulation of ageing: genomic and epigenetic approaches. Mech Ageing Dev 127, 584-589.
-
(2006)
Mech Ageing Dev
, vol.127
, pp. 584-589
-
-
Mathers, J.C.1
-
72
-
-
53849099993
-
Session 2: Personalised nutrition. Epigenomics: a basis for understanding individual differences?
-
Mathers, J.C. 2008. Session 2: Personalised nutrition. Epigenomics: a basis for understanding individual differences? Proc Nutr Soc 67, 390-394.
-
(2008)
Proc Nutr Soc
, vol.67
, pp. 390-394
-
-
Mathers, J.C.1
-
73
-
-
77957357388
-
'Nutrition, Epigenomics and the Development of Obesity: How the Genome Learns from Experience'
-
In: L. Dube, A. Bechara, A. Dagher, A. Drewnowski, J. LeBel, P. James & R.Y. Yada (eds), 1st edn Academic Press, Amsterdam.
-
Mathers, J.C. 2010. 'Nutrition, Epigenomics and the Development of Obesity: How the Genome Learns from Experience'. In: L. Dube, A. Bechara, A. Dagher, A. Drewnowski, J. LeBel, P. James & R.Y. Yada (eds) Obesity Prevention: The Role of Brain and Society on Individual Behaviour, 1st edn, pp. 191-199. Academic Press, Amsterdam.
-
(2010)
Obesity Prevention: The Role of Brain and Society on Individual Behaviour
, pp. 191-199
-
-
Mathers, J.C.1
-
74
-
-
68949146690
-
'Nutrition, epigenetics and aging'
-
In: S.W. Choi & S. Friso (eds) CRC Press (Taylor and Francis Group), Boca Raton.
-
Mathers, J.C. & Ford, D. 2009. 'Nutrition, epigenetics and aging'. In: S.W. Choi & S. Friso (eds) Nutrients and Epigenetics, pp. 175-205. CRC Press (Taylor and Francis Group), Boca Raton.
-
(2009)
Nutrients and Epigenetics
, pp. 175-205
-
-
Mathers, J.C.1
Ford, D.2
-
75
-
-
77957333258
-
Induction of epigenetic alterations by dietary and other environmental factors
-
Mathers, J.C., Strathdee, G. & Relton, C.L. 2010. Induction of epigenetic alterations by dietary and other environmental factors. Adv Genet 71, 3-39.
-
(2010)
Adv Genet
, vol.71
, pp. 3-39
-
-
Mathers, J.C.1
Strathdee, G.2
Relton, C.L.3
-
76
-
-
0027533513
-
Effects of energy restriction on age-associated changes of DNA methylation in mouse liver
-
Miyamura, Y., Tawa, R., Koizumi, A., Uehara, Y., Kurishita, A., Sakurai, H., Kamiyama, S. & Ono, T. 1993. Effects of energy restriction on age-associated changes of DNA methylation in mouse liver. Mutat Res 295, 63-69.
-
(1993)
Mutat Res
, vol.295
, pp. 63-69
-
-
Miyamura, Y.1
Tawa, R.2
Koizumi, A.3
Uehara, Y.4
Kurishita, A.5
Sakurai, H.6
Kamiyama, S.7
Ono, T.8
-
77
-
-
30744479491
-
Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains
-
Niculescu, M.D., Craciunescu, C.N. & Zeisel, S.H. 2006. Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J 20, 43-49.
-
(2006)
FASEB J
, vol.20
, pp. 43-49
-
-
Niculescu, M.D.1
Craciunescu, C.N.2
Zeisel, S.H.3
-
78
-
-
77957859197
-
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome
-
Ollikainen, M., Smith, K.R., Joo, E.J., Ng, H.K., Andronikos, R., Novakovic, B., Abdul Aziz, N.K., Carlin, J.B., Morley, R., Saffery, R. & Craig, J.M. 2010. DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet 19, 4176-4188.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4176-4188
-
-
Ollikainen, M.1
Smith, K.R.2
Joo, E.J.3
Ng, H.K.4
Andronikos, R.5
Novakovic, B.6
Abdul Aziz, N.K.7
Carlin, J.B.8
Morley, R.9
Saffery, R.10
Craig, J.M.11
-
79
-
-
2642617767
-
Levels and patterns of intrauterine growth retardation in developing countries
-
de Onis, M., Blossner, M. & Villar, J. 1998. Levels and patterns of intrauterine growth retardation in developing countries. Eur J Clin Nutr 52(Suppl. 1), S5-S15.
-
(1998)
Eur J Clin Nutr
, vol.52
, Issue.SUPPL. 1
-
-
de Onis, M.1
Blossner, M.2
Villar, J.3
-
80
-
-
0842328994
-
Lifespan: catch-up growth and obesity in male mice
-
Ozanne, S.E. & Hales, C.N. 2004. Lifespan: catch-up growth and obesity in male mice. Nature 427, 411-412.
-
(2004)
Nature
, vol.427
, pp. 411-412
-
-
Ozanne, S.E.1
Hales, C.N.2
-
81
-
-
77953469917
-
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
-
Petronis, A. 2010. Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature 465, 721-727.
-
(2010)
Nature
, vol.465
, pp. 721-727
-
-
Petronis, A.1
-
82
-
-
0028886772
-
Differential sensitivity to loss of cytosine methyl groups within the hepatic p53 gene of folate/methyl deficient rats
-
Pogribny, I.P., Poirier, L.A. & James, S.J. 1995. Differential sensitivity to loss of cytosine methyl groups within the hepatic p53 gene of folate/methyl deficient rats. Carcinogenesis 16, 2863-2867.
-
(1995)
Carcinogenesis
, vol.16
, pp. 2863-2867
-
-
Pogribny, I.P.1
Poirier, L.A.2
James, S.J.3
-
83
-
-
33846026708
-
Methyl deficiency, alterations in global histone modifications, and carcinogenesis
-
Pogribny, I.P., Tryndyak, V.P., Muskhelishvili, L., Rusyn, I. & Ross, S.A. 2007. Methyl deficiency, alterations in global histone modifications, and carcinogenesis. J Nutr 137, 216S-222S.
-
(2007)
J Nutr
, vol.137
-
-
Pogribny, I.P.1
Tryndyak, V.P.2
Muskhelishvili, L.3
Rusyn, I.4
Ross, S.A.5
-
84
-
-
53149144633
-
Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet
-
Pogribny, I.P., Karpf, A.R., James, S.R., Melnyk, S., Han, T. & Tryndyak, V.P. 2008. Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet. Brain Res 1237, 25-34.
-
(2008)
Brain Res
, vol.1237
, pp. 25-34
-
-
Pogribny, I.P.1
Karpf, A.R.2
James, S.R.3
Melnyk, S.4
Han, T.5
Tryndyak, V.P.6
-
85
-
-
0038523843
-
Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study
-
Pufulete, M., Al-Ghnaniem, R., Leather, A.J., Appleby, P., Gout, S., Terry, C., Emery, P.W. & Sanders, T.A. 2003. Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. Gastroenterology 124, 1240-1248.
-
(2003)
Gastroenterology
, vol.124
, pp. 1240-1248
-
-
Pufulete, M.1
Al-Ghnaniem, R.2
Leather, A.J.3
Appleby, P.4
Gout, S.5
Terry, C.6
Emery, P.W.7
Sanders, T.A.8
-
86
-
-
17644402494
-
Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma
-
Pufulete, M., Al-Ghnaniem, R., Khushal, A., Appleby, P., Harris, N., Gout, S., Emery, P.W. & Sanders, T.A. 2005a. Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma. Gut 54, 648-653.
-
(2005)
Gut
, vol.54
, pp. 648-653
-
-
Pufulete, M.1
Al-Ghnaniem, R.2
Khushal, A.3
Appleby, P.4
Harris, N.5
Gout, S.6
Emery, P.W.7
Sanders, T.A.8
-
87
-
-
16244389260
-
Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer
-
Pufulete, M., Al-Ghnaniem, R., Rennie, J.A., Appleby, P., Harris, N., Gout, S., Emery, P.W. & Sanders, T.A. 2005b. Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer. Br J Cancer 92, 838-842.
-
(2005)
Br J Cancer
, vol.92
, pp. 838-842
-
-
Pufulete, M.1
Al-Ghnaniem, R.2
Rennie, J.A.3
Appleby, P.4
Harris, N.5
Gout, S.6
Emery, P.W.7
Sanders, T.A.8
-
88
-
-
61649113446
-
Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
-
Qin, W., Zhu, W., Shi, H., Hewett, J.E., Ruhlen, R.L., MacDonald, R.S., Rottinghaus, G.E., Chen, Y.C. & Sauter, E.R. 2009. Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women. Nutr Cancer 61, 238-244.
-
(2009)
Nutr Cancer
, vol.61
, pp. 238-244
-
-
Qin, W.1
Zhu, W.2
Shi, H.3
Hewett, J.E.4
Ruhlen, R.L.5
MacDonald, R.S.6
Rottinghaus, G.E.7
Chen, Y.C.8
Sauter, E.R.9
-
89
-
-
34250326306
-
Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes
-
Rada-Iglesias, A., Enroth, S., Ameur, A., Koch, C.M., Clelland, G.K., Respuela-Alonso, P., Wilcox, S., Dovey, O.M., Ellis, P.D., Langford, C.F., Dunham, I., Komorowski, J. & Wadelius, C. 2007. Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes. Genome Res 17, 708-719.
-
(2007)
Genome Res
, vol.17
, pp. 708-719
-
-
Rada-Iglesias, A.1
Enroth, S.2
Ameur, A.3
Koch, C.M.4
Clelland, G.K.5
Respuela-Alonso, P.6
Wilcox, S.7
Dovey, O.M.8
Ellis, P.D.9
Langford, C.F.10
Dunham, I.11
Komorowski, J.12
Wadelius, C.13
-
90
-
-
0033805888
-
Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
-
Rampersaud, G.C., Kauwell, G.P., Hutson, A.D., Cerda, J.J. & Bailey, L.B. 2000. Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am J Clin Nutr 72, 998-1003.
-
(2000)
Am J Clin Nutr
, vol.72
, pp. 998-1003
-
-
Rampersaud, G.C.1
Kauwell, G.P.2
Hutson, A.D.3
Cerda, J.J.4
Bailey, L.B.5
-
91
-
-
0343526326
-
Maternal protein deficiency causes hypermethylation of DNA in the livers of rat fetuses
-
Rees, W.D., Hay, S.M., Brown, D.S., Antipatis, C. & Palmer, R.M. 2000. Maternal protein deficiency causes hypermethylation of DNA in the livers of rat fetuses. J Nutr 130, 1821-1826.
-
(2000)
J Nutr
, vol.130
, pp. 1821-1826
-
-
Rees, W.D.1
Hay, S.M.2
Brown, D.S.3
Antipatis, C.4
Palmer, R.M.5
-
92
-
-
34249279527
-
Stability and flexibility of epigenetic gene regulation in mammalian development
-
Reik, W. 2007. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447, 425-432.
-
(2007)
Nature
, vol.447
, pp. 425-432
-
-
Reik, W.1
-
93
-
-
77952918274
-
Genetic variation in microRNA networks: the implications for cancer research
-
Ryan, B.M., Robles, A.I. & Harris, C.C. 2010. Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 10, 389-402.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 389-402
-
-
Ryan, B.M.1
Robles, A.I.2
Harris, C.C.3
-
94
-
-
77954909570
-
Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns
-
Schneider, E., Pliushch, G., El Hajj, N., Galetzka, D., Puhl, A., Schorsch, M., Frauenknecht, K., Riepert, T., Tresch, A., Muller, A.M., Coerdt, W., Zechner, U. & Haaf, T. 2010. Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns. Nucleic Acids Res 38, 3880-3890.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 3880-3890
-
-
Schneider, E.1
Pliushch, G.2
El Hajj, N.3
Galetzka, D.4
Puhl, A.5
Schorsch, M.6
Frauenknecht, K.7
Riepert, T.8
Tresch, A.9
Muller, A.M.10
Coerdt, W.11
Zechner, U.12
Haaf, T.13
-
95
-
-
0028094764
-
Effects of green tea and black tea on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation, DNA methylation, and lung tumorigenesis in A/J mice
-
Shi, S.T., Wang, Z.Y., Smith, T.J., Hong, J.Y., Chen, W.F., Ho, C.T. & Yang, C.S. 1994. Effects of green tea and black tea on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation, DNA methylation, and lung tumorigenesis in A/J mice. Cancer Res 54, 4641-4647.
-
(1994)
Cancer Res
, vol.54
, pp. 4641-4647
-
-
Shi, S.T.1
Wang, Z.Y.2
Smith, T.J.3
Hong, J.Y.4
Chen, W.F.5
Ho, C.T.6
Yang, C.S.7
-
96
-
-
0037272902
-
The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon
-
Sohn, K.J., Stempak, J.M., Reid, S., Shirwadkar, S., Mason, J.B. & Kim, Y.I. 2003. The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon. Carcinogenesis 24, 81-90.
-
(2003)
Carcinogenesis
, vol.24
, pp. 81-90
-
-
Sohn, K.J.1
Stempak, J.M.2
Reid, S.3
Shirwadkar, S.4
Mason, J.B.5
Kim, Y.I.6
-
97
-
-
0029065851
-
AP-1 DNA-binding activity is inhibited by selenite and selenodiglutathione
-
Spyrou, G., Bjornstedt, M., Kumar, S. & Holmgren, A. 1995. AP-1 DNA-binding activity is inhibited by selenite and selenodiglutathione. FEBS Lett 368, 59-63.
-
(1995)
FEBS Lett
, vol.368
, pp. 59-63
-
-
Spyrou, G.1
Bjornstedt, M.2
Kumar, S.3
Holmgren, A.4
-
98
-
-
70649097099
-
Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child
-
Steegers-Theunissen, R.P., Obermann-Borst, S.A., Kremer, D., Lindemans, J., Siebel, C., Steegers, E.A., Slagboom, P.E. & Heijmans, B.T. 2009. Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child. PLoS ONE 4, e7845.
-
(2009)
PLoS ONE
, vol.4
-
-
Steegers-Theunissen, R.P.1
Obermann-Borst, S.A.2
Kremer, D.3
Lindemans, J.4
Siebel, C.5
Steegers, E.A.6
Slagboom, P.E.7
Heijmans, B.T.8
-
99
-
-
60249090649
-
Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis
-
Stothard, K.J., Tennant, P.W., Bell, R. & Rankin, J. 2009. Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis. JAMA 301, 636-650.
-
(2009)
JAMA
, vol.301
, pp. 636-650
-
-
Stothard, K.J.1
Tennant, P.W.2
Bell, R.3
Rankin, J.4
-
100
-
-
75449118269
-
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction
-
van Straten, E.M., Bloks, V.W., Huijkman, N.C., Baller, J.F., Meer, H., Lutjohann, D., Kuipers, F. & Plosch, T. 2010. The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction. Am J Physiol Regul Integr Comp Physiol 298, R275-R282.
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.298
-
-
van Straten, E.M.1
Bloks, V.W.2
Huijkman, N.C.3
Baller, J.F.4
Meer, H.5
Lutjohann, D.6
Kuipers, F.7
Plosch, T.8
-
101
-
-
77956481228
-
Tissue-specific dysregulation of DNA methylation in aging
-
Thompson, R.F., Atzmon, G., Gheorghe, C., Liang, H.Q., Lowes, C., Greally, J.M. & Barzilai, N. 2010a. Tissue-specific dysregulation of DNA methylation in aging. Aging Cell 9, 506-518.
-
(2010)
Aging Cell
, vol.9
, pp. 506-518
-
-
Thompson, R.F.1
Atzmon, G.2
Gheorghe, C.3
Liang, H.Q.4
Lowes, C.5
Greally, J.M.6
Barzilai, N.7
-
102
-
-
77952061606
-
Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats
-
Thompson, R.F., Fazzari, M.J., Niu, H., Barzilai, N., Simmons, R.A. & Greally, J.M. 2010b. Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats. J Biol Chem 285, 15111-15118.
-
(2010)
J Biol Chem
, vol.285
, pp. 15111-15118
-
-
Thompson, R.F.1
Fazzari, M.J.2
Niu, H.3
Barzilai, N.4
Simmons, R.A.5
Greally, J.M.6
-
103
-
-
79959542741
-
The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated by selenium deficiency in Caco-2 Cells and rat colon mucosa
-
2010 Jul 15. [Epub ahead of print, DOI: 10.1007/s12011-010-8764-4].
-
Uthus, E., Begaye, A., Ross, S. & Zeng, H. 2010. The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated by selenium deficiency in Caco-2 Cells and rat colon mucosa. Biol Trace Elem Res 2010 Jul 15. [Epub ahead of print, DOI: 10.1007/s12011-010-8764-4].
-
(2010)
Biol Trace Elem Res
-
-
Uthus, E.1
Begaye, A.2
Ross, S.3
Zeng, H.4
-
104
-
-
77952264863
-
Prenatal programming of kidney disease
-
Vehaskari, V.M. 2010. Prenatal programming of kidney disease. Curr Opin Pediatr 22, 176-182.
-
(2010)
Curr Opin Pediatr
, vol.22
, pp. 176-182
-
-
Vehaskari, V.M.1
-
105
-
-
51849168968
-
Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer
-
de Vogel, S., Bongaerts, B.W., Wouters, K.A., Kester, A.D., Schouten, L.J., de Goeij, A.F., de Bruine, A.P., Goldbohm, R.A., van den Brandt, P.A., van Engeland, M. & Weijenberg, M.P. 2008. Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer. Carcinogenesis 29, 1765-1773.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1765-1773
-
-
de Vogel, S.1
Bongaerts, B.W.2
Wouters, K.A.3
Kester, A.D.4
Schouten, L.J.5
de Goeij, A.F.6
de Bruine, A.P.7
Goldbohm, R.A.8
van den Brandt, P.A.9
van Engeland, M.10
Weijenberg, M.P.11
-
106
-
-
78751567821
-
Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer
-
de Vogel, S, Wouters, K.A., Gottschalk, R.W., van Schooten, F.J., de Goeij, A.F., de Bruïne, A.P., Goldbohm, R.A., van den Brandt, P.A., van Engeland, M & Weijenberg, M.P. 2011. Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer. Cancer Causes Control 22, 1-12.
-
(2011)
Cancer Causes Control
, vol.22
, pp. 1-12
-
-
de Vogel, S.1
Wouters, K.A.2
Gottschalk, R.W.3
van Schooten, F.J.4
de Goeij, A.F.5
de Bruïne, A.P.6
Goldbohm, R.A.7
van den Brandt, P.A.8
van Engeland, M.9
Weijenberg, M.P.10
-
107
-
-
33846217828
-
Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer
-
Wang, L.G., Beklemisheva, A., Liu, X.M., Ferrari, A.C., Feng, J. & Chiao, J.W. 2007. Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer. Mol Carcinog 46, 24-31.
-
(2007)
Mol Carcinog
, vol.46
, pp. 24-31
-
-
Wang, L.G.1
Beklemisheva, A.2
Liu, X.M.3
Ferrari, A.C.4
Feng, J.5
Chiao, J.W.6
-
108
-
-
0043093697
-
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
-
Waterland, R.A. & Jirtle, R.L. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 23, 5293-5300.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5293-5300
-
-
Waterland, R.A.1
Jirtle, R.L.2
-
109
-
-
33749026098
-
Maternal methyl supplements increase offspring DNA methylation at Axin Fused
-
Waterland, R.A., Dolinoy, D.C., Lin, J.R., Smith, C.A., Shi, X. & Tahiliani, K.G. 2006. Maternal methyl supplements increase offspring DNA methylation at Axin Fused. Genesis 44, 401-406.
-
(2006)
Genesis
, vol.44
, pp. 401-406
-
-
Waterland, R.A.1
Dolinoy, D.C.2
Lin, J.R.3
Smith, C.A.4
Shi, X.5
Tahiliani, K.G.6
-
110
-
-
62849107573
-
Body-mass index and cause-specific mortality in 900000 adults: collaborative analyses of 57 prospective studies
-
Whitlock, G., Lewington, S., Sherliker, P., Clarke, R., Emberson, J., Halsey, J., Qizilbash, N., Collins, R. & Peto, R. 2009. Body-mass index and cause-specific mortality in 900000 adults: collaborative analyses of 57 prospective studies. Lancet 373, 1083-1096.
-
(2009)
Lancet
, vol.373
, pp. 1083-1096
-
-
Whitlock, G.1
Lewington, S.2
Sherliker, P.3
Clarke, R.4
Emberson, J.5
Halsey, J.6
Qizilbash, N.7
Collins, R.8
Peto, R.9
-
111
-
-
77952859811
-
High-fat diet leads to a decreased methylation of the Mc4r gene in the obese BFMI and the lean B6 mouse lines
-
Widiker, S., Karst, S., Wagener, A. & Brockmann, G.A. 2010. High-fat diet leads to a decreased methylation of the Mc4r gene in the obese BFMI and the lean B6 mouse lines. J Appl Genet 51, 193-197.
-
(2010)
J Appl Genet
, vol.51
, pp. 193-197
-
-
Widiker, S.1
Karst, S.2
Wagener, A.3
Brockmann, G.A.4
-
112
-
-
0031873353
-
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice
-
Wolff, G.L., Kodell, R.L., Moore, S.R. & Cooney, C.A. 1998. Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice. FASEB J 12, 949-957.
-
(1998)
FASEB J
, vol.12
, pp. 949-957
-
-
Wolff, G.L.1
Kodell, R.L.2
Moore, S.R.3
Cooney, C.A.4
-
113
-
-
79955671723
-
-
World Health Organisation Diet, Nutrition and the Prevention of Chronic Diseases: Report of a Joint WHO/FAO Expert Consultation, WHO Technical Report Series 916. Pub. World Health Organisation, Geneva.
-
World Health Organisation 2003. Diet, Nutrition and the Prevention of Chronic Diseases: Report of a Joint WHO/FAO Expert Consultation, WHO Technical Report Series 916. Pub. World Health Organisation, Geneva.
-
(2003)
-
-
-
114
-
-
56049083256
-
Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells
-
Xiang, N., Zhao, R., Song, G. & Zhong, W. 2008. Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells. Carcinogenesis 29, 2175-2181.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2175-2181
-
-
Xiang, N.1
Zhao, R.2
Song, G.3
Zhong, W.4
-
115
-
-
78049404909
-
Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information
-
Zaidi, S.K., Young, D.W., Montecino, M., Lian, J.B., Stein, J.L., van Wijnen, A.J. & Stein, G.S. 2010. Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information. Mol Cell Biol 30, 4758-4766.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 4758-4766
-
-
Zaidi, S.K.1
Young, D.W.2
Montecino, M.3
Lian, J.B.4
Stein, J.L.5
van Wijnen, A.J.6
Stein, G.S.7
-
116
-
-
0030050728
-
Inhibition of catechol O-methyltransferase-catalyzed O-methylation of 2- and 4-hydroxyestradiol by quercetin. Possible role in estradiol-induced tumorigenesis
-
Zhu, B.T. & Liehr, J.G. 1996. Inhibition of catechol O-methyltransferase-catalyzed O-methylation of 2- and 4-hydroxyestradiol by quercetin. Possible role in estradiol-induced tumorigenesis. J Biol Chem 271, 1357-1363.
-
(1996)
J Biol Chem
, vol.271
, pp. 1357-1363
-
-
Zhu, B.T.1
Liehr, J.G.2
-
117
-
-
0028085081
-
Catechol-O-methyltransferase-catalyzed rapid O-methylation of mutagenic flavonoids. Metabolic inactivation as a possible reason for their lack of carcinogenicity in vivo
-
Zhu, B.T., Ezell, E.L. & Liehr, J.G. 1994. Catechol-O-methyltransferase-catalyzed rapid O-methylation of mutagenic flavonoids. Metabolic inactivation as a possible reason for their lack of carcinogenicity in vivo. J Biol Chem 269, 292-299.
-
(1994)
J Biol Chem
, vol.269
, pp. 292-299
-
-
Zhu, B.T.1
Ezell, E.L.2
Liehr, J.G.3
-
118
-
-
0033827207
-
O-Methylation of tea polyphenols catalyzed by human placental cytosolic catechol-O-methyltransferase
-
Zhu, B.T., Patel, U.K., Cai, M.X. & Conney, A.H. 2000. O-Methylation of tea polyphenols catalyzed by human placental cytosolic catechol-O-methyltransferase. Drug Metab Dispos 28, 1024-1030.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1024-1030
-
-
Zhu, B.T.1
Patel, U.K.2
Cai, M.X.3
Conney, A.H.4
-
119
-
-
0035689854
-
Rapid conversion of tea catechins to monomethylated products by rat liver cytosolic catechol-O-methyltransferase
-
Zhu, B.T., Patel, U.K., Cai, M.X., Lee, A.J. & Conney, A.H. 2001. Rapid conversion of tea catechins to monomethylated products by rat liver cytosolic catechol-O-methyltransferase. Xenobiotica 31, 879-890.
-
(2001)
Xenobiotica
, vol.31
, pp. 879-890
-
-
Zhu, B.T.1
Patel, U.K.2
Cai, M.X.3
Lee, A.J.4
Conney, A.H.5
|