메뉴 건너뛰기




Volumn 8, Issue 1, 2011, Pages 37-46

Genetics of depression: Implications for clinical practice yet?

Author keywords

Antidepressant response; Genetics; Major depressive disorder; Pharmacokinetic genes; Phenotypic outcome

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CITALOPRAM; CYTOCHROME P450; FK 506 BINDING PROTEIN; KAINIC ACID RECEPTOR; MU OPIATE RECEPTOR; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHODIESTERASE 4A; PHOSPHODIESTERASE IV; PROTEIN GRIK4; PROTEIN TREK1; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE; UNCLASSIFIED DRUG;

EID: 79955608149     PISSN: 17244935     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (105)
  • 1
    • 0023183294 scopus 로고
    • Familial rates of affective disorder. A report from the National Institute of Mental Health Collaborative Study
    • Andreasen NC, Rice J, Endicott J, Coryell W, Grove WM, Reich T (1987). Familial rates of affective disorder. A report from the National Institute of Mental Health Collaborative Study. Arch Gen Psychiatry 44, 5, 461-9.
    • (1987) Arch Gen Psychiatry , vol.44 , Issue.5 , pp. 461-469
    • Andreasen, N.C.1    Rice, J.2    Endicott, J.3    Coryell, W.4    Grove, W.M.5    Reich, T.6
  • 4
    • 0022993383 scopus 로고
    • Recurrent and nonrecurrent depression. A family study
    • Bland RC, Newman SC, Orn H (1986). Recurrent and nonrecurrent depression. A family study. Arch Gen Psychiatry 43, 11, 1085-9.
    • (1986) Arch Gen Psychiatry , vol.43 , Issue.11 , pp. 1085-1089
    • Bland, R.C.1    Newman, S.C.2    Orn, H.3
  • 5
    • 37349069210 scopus 로고    scopus 로고
    • Expression of phosphodiesterase 4 is altered in the brains of subjects with autism
    • Braun NN, Reutiman TJ, Lee S, Folsom TD, Fatemi SH (2007). Expression of phosphodiesterase 4 is altered in the brains of subjects with autism. Neuroreport 18, 17, 1841-4.
    • (2007) Neuroreport , vol.18 , Issue.17 , pp. 1841-1844
    • Braun, N.N.1    Reutiman, T.J.2    Lee, S.3    Folsom, T.D.4    Fatemi, S.H.5
  • 6
    • 0017871010 scopus 로고
    • Evidence for genetic inheritance of primary affective disorder in adoptees
    • Cadoret RJ (1978). Evidence for genetic inheritance of primary affective disorder in adoptees. Am J Psychiatry 135, 4, 463-6.
    • (1978) Am J Psychiatry , vol.135 , Issue.4 , pp. 463-466
    • Cadoret, R.J.1
  • 10
    • 37349093041 scopus 로고    scopus 로고
    • Recommendations from the EGAPP Working Group: Testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors
    • EGAPP
    • EGAPP (2007). Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors. Genet Med 9, 12, 819-25.
    • (2007) Genet Med , vol.9 , Issue.12 , pp. 819-825
  • 13
    • 70349572815 scopus 로고    scopus 로고
    • Genetic studies of drug response and side effects in the STAR*D study, part 1
    • Garriock HA, Hamilton SP (2009a). Genetic studies of drug response and side effects in the STAR*D study, part 1. J Clin Psychiatry 70, 8, 1186-7.
    • (2009) J Clin Psychiatry , vol.70 , Issue.8 , pp. 1186-1187
    • Garriock, H.A.1    Hamilton, S.P.2
  • 14
    • 70350463843 scopus 로고    scopus 로고
    • Genetic studies of drug response and side effects in the STAR*D study, part 2
    • Garriock HA, Hamilton SP (2009b). Genetic studies of drug response and side effects in the STAR*D study, part 2. J Clin Psychiatry 70, 9, 1323-5.
    • (2009) J Clin Psychiatry , vol.70 , Issue.9 , pp. 1323-1325
    • Garriock, H.A.1    Hamilton, S.P.2
  • 18
    • 13444280555 scopus 로고    scopus 로고
    • The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression
    • Gillespie NA, Whitfield JB, Williams B, Heath AC, Martin NG (2005). The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression. Psychol Med 35, 1, 101-11.
    • (2005) Psychol Med , vol.35 , Issue.1 , pp. 101-111
    • Gillespie, N.A.1    Whitfield, J.B.2    Williams, B.3    Heath, A.C.4    Martin, N.G.5
  • 19
    • 13244260769 scopus 로고    scopus 로고
    • Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden
    • Grabe HJ, Lange M, Wolff B, Volzke H, Lucht M, Freyberger HJ, John U, Cascorbi I (2005). Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden. Mol Psychiatry 10, 2, 220-4.
    • (2005) Mol Psychiatry , vol.10 , Issue.2 , pp. 220-224
    • Grabe, H.J.1    Lange, M.2    Wolff, B.3    Volzke, H.4    Lucht, M.5    Freyberger, H.J.6    John, U.7    Cascorbi, I.8
  • 27
    • 33748324559 scopus 로고    scopus 로고
    • Stress-related negative affectivity and genetically altered serotonin transporter function: Evidence of synergism in shaping risk of depression
    • Jacobs N, Kenis G, Peeters F, Derom C, Vlietinck R, van Os J (2006). Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression. Arch Gen Psychiatry 63, 9, 989-96.
    • (2006) Arch Gen Psychiatry , vol.63 , Issue.9 , pp. 989-996
    • Jacobs, N.1    Kenis, G.2    Peeters, F.3    Derom, C.4    Vlietinck, R.5    van Os, J.6
  • 30
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: A replication
    • Kendler KS, Kuhn JW, Vittum J, Prescott CA, Riley B (2005). The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication. Arch Gen Psychiatry 62, 5, 529-35.
    • (2005) Arch Gen Psychiatry , vol.62 , Issue.5 , pp. 529-535
    • Kendler, K.S.1    Kuhn, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 31
    • 36348996093 scopus 로고    scopus 로고
    • The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults
    • Kilpatrick DG, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Resnick HS, Roitzsch J, Boyle J, Gelernter J (2007). The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. Am J Psychiatry 164, 11, 1693-9.
    • (2007) Am J Psychiatry , vol.164 , Issue.11 , pp. 1693-1699
    • Kilpatrick, D.G.1    Koenen, K.C.2    Ruggiero, K.J.3    Acierno, R.4    Galea, S.5    Resnick, H.S.6    Roitzsch, J.7    Boyle, J.8    Gelernter, J.9
  • 34
    • 70249083016 scopus 로고    scopus 로고
    • Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients
    • Laje G, Allen AS, Akula N, Manji H, John Rush A, McMahon FJ (2009). Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients. Pharmacogenet Genomics 19, 9, 666-74.
    • (2009) Pharmacogenet Genomics , vol.19 , Issue.9 , pp. 666-674
    • Laje, G.1    Allen, A.S.2    Akula, N.3    Manji, H.4    John, R.A.5    McMahon, F.J.6
  • 39
    • 69449094432 scopus 로고    scopus 로고
    • Family-based association study between brain-derived neurotrophic factor gene and major depressive disorder of Chinese descent
    • Liu X, Xu Y, Jiang S, Cui D, Qian Y, Jiang K (2009). Family-based association study between brain-derived neurotrophic factor gene and major depressive disorder of Chinese descent. Psychiatry Res 169, 2,169-72.
    • (2009) Psychiatry Res , vol.169 , Issue.2 , pp. 169-172
    • Liu, X.1    Xu, Y.2    Jiang, S.3    Cui, D.4    Qian, Y.5    Jiang, K.6
  • 41
    • 41149146056 scopus 로고    scopus 로고
    • Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients
    • Lotrich, F. E., B. G. Pollock, et al. (2008). Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients. J Psychiatry Neurosci 33, 2, 123-30.
    • (2008) J Psychiatry Neurosci , vol.33 , Issue.2 , pp. 123-130
    • Lotrich, F.E.1    Pollock, B.G.2
  • 43
    • 0033104318 scopus 로고    scopus 로고
    • Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene
    • Manuck SB, Flory JD, Ferrell RE, Dent KM, Mann JJ, Muldoon MF (1999). Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene. Biol Psychiatry 45, 5, 603-14.
    • (1999) Biol Psychiatry , vol.45 , Issue.5 , pp. 603-614
    • Manuck, S.B.1    Flory, J.D.2    Ferrell, R.E.3    Dent, K.M.4    Mann, J.J.5    Muldoon, M.F.6
  • 44
    • 0023511640 scopus 로고
    • Hazard, heredity and depression. A family study
    • McGuffin P, Katz R, Bebbington P (1987). Hazard, heredity and depression. A family study. J Psychiatr Res 21, 4,365-75.
    • (1987) J Psychiatr Res , vol.21 , Issue.4 , pp. 365-375
    • McGuffin, P.1    Katz, R.2    Bebbington, P.3
  • 48
    • 0017642345 scopus 로고
    • Adoption study supporting genetic transmission in manic-depressive illness
    • Mendlewicz J, Rainer JD (1977). Adoption study supporting genetic transmission in manic-depressive illness. Nature 268, 5618, 327-9.
    • (1977) Nature , vol.268 , Issue.5618 , pp. 327-329
    • Mendlewicz, J.1    Rainer, J.D.2
  • 49
    • 0023776106 scopus 로고
    • Parental concordance for affective disorders: Psychopathology in offspring
    • Merikangas KR, Prusoff BA, Weissman MM (1988). Parental concordance for affective disorders: psychopathology in offspring. J Affect Disord 15, 3, 279-90.
    • (1988) J Affect Disord , vol.15 , Issue.3 , pp. 279-290
    • Merikangas, K.R.1    Prusoff, B.A.2    Weissman, M.M.3
  • 52
    • 85047695157 scopus 로고    scopus 로고
    • Association between a serotonin transporter promoter region polymorphism and mood response during tryptophan depletion
    • Moreno FA, Rowe DC, Kaiser B, Chase D, Michaels T, Gelernter J, Delgado PL (2002). Association between a serotonin transporter promoter region polymorphism and mood response during tryptophan depletion. Mol Psychiatry 7, 2, 213-6.
    • (2002) Mol Psychiatry , vol.7 , Issue.2 , pp. 213-216
    • Moreno, F.A.1    Rowe, D.C.2    Kaiser, B.3    Chase, D.4    Michaels, T.5    Gelernter, J.6    Delgado, P.L.7
  • 56
    • 7744233997 scopus 로고    scopus 로고
    • Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression
    • Murphy GM Jr, SB Hollander, et al. (2004). Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression. Arch Gen Psychiatry 61, 11, 1163-9.
    • (2004) Arch Gen Psychiatry , vol.61 , Issue.11 , pp. 1163-1169
    • Murphy Jr., G.M.1    Hollander, S.B.2
  • 58
    • 0036724341 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: Evidence from a family-based association study
    • Neves-Pereira M, Mundo E, Muglia P, King N, Macciardi F, Kennedy JL (2002). The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet 71, 3, 651-5.
    • (2002) Am J Hum Genet , vol.71 , Issue.3 , pp. 651-655
    • Neves-Pereira, M.1    Mundo, E.2    Muglia, P.3    King, N.4    Macciardi, F.5    Kennedy, J.L.6
  • 61
    • 50249189084 scopus 로고    scopus 로고
    • Pharmacogenetic Analysis of Genes Implicated in Rodent Models of Antidepressant Response: Association of TREK1 and Treatment Resistance in the STAR(*)D Study
    • Perlis RH, Moorjani P, Fagerness J, Purcell S, Trivedi MH, Fava M, Rush AJ, Smoller JW (2008). Pharmacogenetic Analysis of Genes Implicated in Rodent Models of Antidepressant Response: Association of TREK1 and Treatment Resistance in the STAR(*)D Study. Neuropsycho-pharmacology 33, 12, 2810-9
    • (2008) Neuropsycho-pharmacology , vol.33 , Issue.12 , pp. 2810-2819
    • Perlis, R.H.1    Moorjani, P.2    Fagerness, J.3    Purcell, S.4    Trivedi, M.H.5    Fava, M.6    Rush, A.J.7    Smoller, J.W.8
  • 62
    • 68949196334 scopus 로고    scopus 로고
    • When is pharmacogenetic testing for antidepressant response ready for the clinic? A cost-effectiveness analysis based on data from the STAR*D study
    • Perlis RH, A Patrick, et al. (2009). When is pharmacogenetic testing for antidepressant response ready for the clinic? A cost-effectiveness analysis based on data from the STAR*D study. Neuropsychopharmacology 34, 10, 2227-36.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.10 , pp. 2227-2236
    • Perlis, R.H.1    Patrick, A.2
  • 66
    • 0030907363 scopus 로고    scopus 로고
    • Psychiatric disorders in the relatives of depressed probands. II. Familial loading for comorbid non-depressive disorders based upon proband age of onset
    • Rende R, Weissman M, Rutter M, Wickramaratne P, Harrington R, Pickles A (1997). Psychiatric disorders in the relatives of depressed probands. II. Familial loading for comorbid non-depressive disorders based upon proband age of onset. J Affect Disord 42, 1, 23-8.
    • (1997) J Affect Disord , vol.42 , Issue.1 , pp. 23-28
    • Rende, R.1    Weissman, M.2    Rutter, M.3    Wickramaratne, P.4    Harrington, R.5    Pickles, A.6
  • 68
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: A meta-analysis
    • Risch N, Herrell R, Lehner T, Liang KY, Eaves L, Hoh J, Griem Kovacs M, Ott J, Merikangas KR (2009). Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA 301, 23, 2462-71.
    • (2009) JAMA , vol.301 , Issue.23 , pp. 2462-2471
    • Risch, N.1    Herrell, R.2    Lehner, T.3    Liang, K.Y.4    Eaves, L.5    Hoh, J.6    Griem, K.M.7    Ott, J.8    Merikangas, K.R.9
  • 71
    • 34548395111 scopus 로고    scopus 로고
    • The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
    • Schmidt HD, Duman RS (2007). The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav Pharmacol 18, 5-6, 391-418.
    • (2007) Behav Pharmacol , vol.18 , Issue.5-6 , pp. 391-418
    • Schmidt, H.D.1    Duman, R.S.2
  • 72
    • 0032781402 scopus 로고    scopus 로고
    • Tryptophan hydroxylase gene and response to lithium prophylaxis in mood disorders
    • Serretti A, Lilli R, Lorenzi C, Gasperini M, Smeraldi E (1999). Tryptophan hydroxylase gene and response to lithium prophylaxis in mood disorders. J Psychiatr Res 33, 5, 3717.
    • (1999) J Psychiatr Res , vol.33 , Issue.5 , pp. 3717
    • Serretti, A.1    Lilli, R.2    Lorenzi, C.3    Gasperini, M.4    Smeraldi, E.5
  • 81
    • 0033810465 scopus 로고    scopus 로고
    • Genetic epidemiology of major depression: Review and metaanalysis
    • Sullivan PF, Neale MC, Kendler KS (2000). Genetic epidemiology of major depression: review and metaanalysis. Am J Psychiatry 157, 10, 1552-62.
    • (2000) Am J Psychiatry , vol.157 , Issue.10 , pp. 1552-1562
    • Sullivan, P.F.1    Neale, M.C.2    Kendler, K.S.3
  • 82
    • 32144435933 scopus 로고    scopus 로고
    • Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder
    • Surtees PG, Wainwright NW, Willis-Owen SA, Luben R, Day NE, Flint J (2006). Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder. Biol Psychiatry 59, 3, 224-9.
    • (2006) Biol Psychiatry , vol.59 , Issue.3 , pp. 224-229
    • Surtees, P.G.1    Wainwright, N.W.2    Willis-Owen, S.A.3    Luben, R.4    Day, N.E.5    Flint, J.6
  • 83
    • 0033576742 scopus 로고    scopus 로고
    • Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors
    • Tsai SJ, Hong CJ, Wang YC (1999). Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors. Neuroreport 10, 18, 3773-5.
    • (1999) Neuroreport , vol.10 , Issue.18 , pp. 3773-3775
    • Tsai, S.J.1    Hong, C.J.2    Wang, Y.C.3
  • 89
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • W.T.C.C
    • W.T.C.C. (2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 7145, 661-78.
    • (2007) Nature , vol.447 , Issue.7145 , pp. 661-678
  • 93
    • 0022979463 scopus 로고
    • Psychiatric disorders in the biological and adoptive families of adopted individuals with affective disorders
    • Wender PH, Kety SS, Rosenthal D, Schulsinger F, Ortmann J, Lunde I (1986). Psychiatric disorders in the biological and adoptive families of adopted individuals with affective disorders. Arch Gen Psychiatry 43, 10, 923-9.
    • (1986) Arch Gen Psychiatry , vol.43 , Issue.10 , pp. 923-929
    • Wender, P.H.1    Kety, S.S.2    Rosenthal, D.3    Schulsinger, F.4    Ortmann, J.5    Lunde, I.6
  • 97
    • 85047697355 scopus 로고    scopus 로고
    • Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression
    • Zalsman G, Huang YY, Oquendo MA, Burke AK, Hu XZ, Brent DA, Ellis SP, Goldman D, Mann JJ (2006). Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression. Am J Psychiatry 163, 9, 1588-93.
    • (2006) Am J Psychiatry , vol.163 , Issue.9 , pp. 1588-1593
    • Zalsman, G.1    Huang, Y.Y.2    Oquendo, M.A.3    Burke, A.K.4    Hu, X.Z.5    Brent, D.A.6    Ellis, S.P.7    Goldman, D.8    Mann, J.J.9
  • 101
    • 46949092427 scopus 로고    scopus 로고
    • Effects of the G(-656)A variant on CREB1 promoter activity in a glial cell line: Interactions with gonadal steroids and stress
    • Zubenko GS, Hughes HB 3rd (2008). Effects of the G(-656)A variant on CREB1 promoter activity in a glial cell line: Interactions with gonadal steroids and stress. Am J Med Genet B Neuropsychiatr Genet 147B, 5, 579-85.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , Issue.5 , pp. 579-585
    • Zubenko, G.S.1    Hughes III, H.B.2
  • 102
    • 62849128403 scopus 로고    scopus 로고
    • Effects of the G(-656)A variant on CREB1 promoter activity in a neuronal cell line: Interactions with gonadal steroids and stress
    • Zubenko GS, Hughes HB (2008). Effects of the G(-656)A variant on CREB1 promoter activity in a neuronal cell line: Interactions with gonadal steroids and stress. Mol Psychiatry 14, 390-397.
    • (2008) Mol Psychiatry , vol.14 , pp. 390-397
    • Zubenko, G.S.1    Hughes, H.B.2
  • 103
    • 0037045146 scopus 로고    scopus 로고
    • Genetic linkage of region containing the CREB1 gene to depressive disorders in women from families with recurrent, early-onset, major depression
    • Zubenko GS, Hughes HB 3rd, Maher BS, Stiffler JS, Zubenko WN, Marazita ML (2002). Genetic linkage of region containing the CREB1 gene to depressive disorders in women from families with recurrent, early-onset, major depression. Am J Med Genet 114, 8, 980-7.
    • (2002) Am J Med Genet , vol.114 , Issue.8 , pp. 980-987
    • Zubenko, G.S.1    Hughes III, H.B.2    Maher, B.S.3    Stiffler, J.S.4    Zubenko, W.N.5    Marazita, M.L.6
  • 105
    • 0142157161 scopus 로고    scopus 로고
    • Genome-wide linkage survey for genetic loci that influence the development of depressive disorders in families with recurrent, early-onset, major depression
    • Zubenko GS, Maher B, Hughes HB 3rd, Zubenko WN, Stiffler JS, Kaplan BB, Marazita ML (2003). Genome-wide linkage survey for genetic loci that influence the development of depressive disorders in families with recurrent, early-onset, major depression. Am J Med Genet B Neuropsychiatr Genet 123, 1, 1-18.
    • (2003) Am J Med Genet B Neuropsychiatr Genet , vol.123 , Issue.1 , pp. 1-18
    • Zubenko, G.S.1    Maher, B.2    Hughes III, H.B.3    Zubenko, W.N.4    Stiffler, J.S.5    Kaplan, B.B.6    Marazita, M.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.