Whole genome linkage scan of recurrent depressive disorder from the depression network study

Human Molecular Genetics

Volumn 14, Issue 22, 2005, Pages 3337-3345

  McGuffin, Peter ^a   Knight, Jo ^a   Breen, Gerome ^a   Brewster, Shyama ^b   Boyd, Peter R ^b   Craddock, Nick ^c,k   Gill, Mike ^d   Korszun, Ania ^e   Maier, Wolfgang ^f   Middleton, Lefkos ^b   Mors, Ole ^g   Owen, Michael J ^c   Perry, Julia ^b   Preisig, Martin ^h   Reich, Theodore ⁱ   Rice, John ⁱ   Rietschel, Marcella ^j   Jones, Lisa ^k   Sham, Pak ^a   Farmer, Anne E ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d TRINITY COLLEGE DUBLIN   (Ireland)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^f UNIVERSITY OF BONN   (Germany)

^g AARHUS UNIVERSITY   (Denmark)

^h DEPT UNIV DE PSYCHIATRIE ADULTE   (Switzerland)

ⁱ WASHINGTON UNIVERSITY   (United States)

^j CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^k UNIVERSITY OF BIRMINGHAM   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRO AMINO ACID OXIDASE; METHYLENETETRAHYDROFOLATE DEHYDROGENASE;

ADULT; ARTICLE; BIPOLAR DEPRESSION; CHROMOSOME 12Q; CHROMOSOME 13Q; CHROMOSOME 15Q; CHROMOSOME 1P; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC LINKAGE; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; PANIC; PRIORITY JOURNAL; RECURRENT DISEASE; SCHIZOPHRENIA; SEX DIFFERENCE;

ADOLESCENT; ADULT; ALLELES; CHROMOSOME MAPPING; DEPRESSIVE DISORDER; FEMALE; GENE FREQUENCY; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); LOD SCORE; MALE; RECURRENCE; TWIN STUDIES;

EID: 27944446099     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi363     Document Type: Article

References (42)

1. McGuffin, P., Katz, R., Watkins, S. and Rutherford, J. (1996) A hospital based twin register of the heritability of DSMIV unipolar depression. Arch. Gen. Psychiatry, 53, 129-136.
2. Kendler, K.S., Neale, M.C., Kessler, R.C., Heath, A.C. and Eaves, L.J. (1993) The lifetime history of major depression in women. Reliability of diagnosis and heritability. Arch. Gen. Psychiatry, 50, 863-870.
3. Jones, I., Kent, L. and Craddock, N. (2002) Genetics of affective disorders. In McGuffin, P., Owen, M.J. and Gottesman, I.I. (eds), Psychiatric Genetics and Genomics. Oxford University Press, Oxford.
4. Farmer, A.E., Harris, T., Redman, K., Sadler, S., Mahmood, A. and McGuffin, P. (2000) The Cardiff Depression Study: A sib-pair study of life-events and familiarity in major depression. Br. J. Psychiatry, 176, 150-155.
5. Brown, G.H. and Harris, T.O. (1978) Social Origins of Depression. A Study of Psychiatric Disorder in Women, 5th edn. Routledge, London.
6. Farmer, A.E. and McGuffin, P. (2003) Humiliation, loss and other types of life events and difficulties: A comparison of depressed subjects, healthy controls and their siblings. Psychol. Med., 33, 1169-1175.
7. Bierut, L.J., Heath, A.C., Bucholz, K.K., Dinwiddie, S.H., Madden, P.A., Statham, D.J., Dunne, M.P. and Martin, N.G. (1999) Major depressive disorder in a community-based twin sample: Are there different genetic and environmental contributions for men and women? Arch. Gen. Psychiatry, 56, 557-563.
8. Agrawal, A., Jacobson, K.C., Gardner, C.O., Prescott, C.A. and Kendler, K,S. (2004) A population based twin study of sex differences in depressive symptoms. Twin Res., 7, 176-181.
9. Sullivan, P.F., Neale, M.C. and Kendler, K.S. (2000) Genetic epidemiology of major depression: Review and meta-analysis. Am. J. Psychiatry, 157, 1552-1562.
10. Segurado, R., Detera-Wadleigh, S.D., Levinson, D.F., Lewis, C.M., Gill, M., Nurnberger, J.I. Jr, Craddock, N., DePaulo, J.R., Baron, M., Gershon, E.S. et al. (2003) Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am. J. Hum. Genet., 73, 49-62.
11. Holmans, P., Zubenko, G.S., Crowe, R.R., DePaulo, J.R. Jr, Scheftner, W.A., Weissman, M.M., Zubenko, W.N., Boutelle, S., Murphy-Eberenz, K., MacKinnon, D. et al. (2004) Genomewide significant linkage to recurrent, early-onset major depressive disorder on chromosome 15q. Am. J. Hum. Genet., 74, 1154-1167.
12. Abkevich, V., Camp, N.J., Hensel, C.H., Neff, C.D., Russell, D.L., Hughes, D.C., Plenk, A.M., Lowry, M.R., Richards, R.L., Carter, C. et al. (2003) Predisposition locus for major depression on chromosome 12q22-12q23.2. Am. J. Hum. Genet., 73, 1271-1281.
13. Nurnberger, J.I. Jr, Foroud, T., Flury, L., Su, J., Meyer, E.T., Hu, K., Crowe, R., Edenberg, H., Goate, A., Bierut, L. et al. (2001) Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder. Am. J. Psychiatry, 158, 718-724.
14. Morton, N.E. (1956) The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type. Am. J. Hum. Genet., 8, 80-96.
15. Badner, J.A. and Gershon, E.S. (2002) Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol. Psychiatry, 7, 405-411.
16. Hamilton, S.P., Fyer, A.J., Durner, M., Heiman, G.A., Baisre de Leon, A., Hodge, S.E., Knowles, J.A. and Weissman, M.M. (2003) Further genetic evidence for a panic disorder syndrome mapping to chromosome 13q. Proc. Natl Acad. Sci. USA, 100, 2550-2555.
17. Kendler, K.S., Neale, M.C., Kessler, R.C., Heath, A.C. and Eaves, L.J. (1992) Major depression and generalized anxiety disorder. Same genes, (partly) different environments? Arch. Gen. Psychiatry, 49, 716-722.
18. Thapar, A. and McGuffin, P. (1997) Anxiety and depressive symptoms in childhood - a genetic study of comorbidity. J. Child Psychol. Psychiatry, 38, 651-656.
19. Turecki, G., Grof, P., Grof, E., D'Souza, V., Lebuis, L., Marineau, C., Cavazzoni, P., Duffy, A., Betard, C., Zvolsky, P. et al. (2001) Mapping susceptibility genes for bipolar disorder: A pharmacogenetic approach based on excellent response to lithium. Mol. Psychiatry, 6, 570-578.
20. Nash, M.W., Huezo-Diaz, P., Williamson, R.J., Sterne, A., Purcell, S., Hoda, F., Cherny, S.S., Abecasis, G.R., Prince, M., Gray, J.A. et al. (2004) Genome-wide linkage analysis of a composite index of neuroticismand mood-related scales in extreme selected sibships. Hum. Mol. Genet., 13, 2173-2182.
21. Lander, E.S. and Kruglyak, L. (1995) Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nat. Genet., 11, 241-247.
22. Bjelland, I., Tell, G.S., Vollset, S.E., Refsum, H. and Ueland, P.M. (2003) Folate, vitamin B12, homocysteine, and the MTHFR 677CT polymorphism in anxiety and depression - The Hordaland Homocysteine Study. Arch. Gen. Psychiatry, 60, 618-626.
23. Hickie, I., Scott, E., Naismith, S., Ward, P.B., Turner, K., Parker, G., Mitchell, P. and Wilhelm, K. (2001) Late-onset depression: Genetic, vascular and clinical contributions. Psychol. Med., 31, 1403-1412.
24. Arinami, T., Yamada, N., Yamakawa-Kobayashi, K., Hamaguchi, H. and Toru, M. (1997) Methylenetetrahydrofolate reductase variant and schizophrenia/ depression. Am. J. Med. Genet., 74, 526-528.
25. Kunugi, H., Fukuda, R., Hattori, M., Kato, T., Tatsumi, M., Sakai, T., Hirose, T. and Nanko, S. (1998) C677T polymorphism in methylenetetrahydrofolate reductase gene and psychoses. Mol. Psychiatry, 3, 435-437.
26. Bjelland, I., Tell, G.S., Vollset, S.E., Refsum, H. and Ueland, P.M. (2003) Folate, vitamin B12, homocysteine, and the MTHFR 677CT polymorphism in anxiety and depression - The Hordaland Homocysteine Study. Arch. Gen. Psychiatry, 60, 618-626.
27. Craddock, N., Owen, M., Burge, S., Kurian, B., Thomas, P. and McGuffin, P. (1994) Familial cosegregation of major affective disorder and Darier's disease (keratosis follicularis). Br. J. Psychiatry, 164, 355-358.
28. Chumakov, I., Blumenfeld, M., Guerassimenko, O., Cavarec, L., Palicio, M., Abderrahim, H., Bougueleret, L., Barry, C., Tanaka, H., La Rosa, P. et al. (2002) Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proc. Natl Acad. Sci. USA, 99, 13675-13680.
29. Craddock, N., O'Donovan, M.C. and Owen, M.J. (2005) The genetics of schizophrenia and bipolar disorder: Dissecting psychosis. J. Med. Genet., 42, 193-204.
30. Weissman, M.M., Fyer, A.J., Haghighi, F., Heiman, G., Deng, Z., Hen, R., Hodge, S.E. and Knowles, J.A. (2000) Potential panic disorder syndrome: clinical and genetic linkage evidence. Am. J. Med. Genet., 96, 24-35.
31. American Psychiatric Association (1994) Diagnostic and Statistical Manual, 4th edn. (DSM-IV). American Psychiatric Press, Washington DC.
32. World Health Organization (1993) The ICD-10 Classification of Mental and Behavioural Disorders. Diagnostic Criteria for Research. World Health Organization, Geneva.
33. Farmer, A., Breen, G., Brewster, S., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. et al. (2004) The Depression Network (DeNt) Study: Methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study. BMC Psychiatry, 4, 42.
34. Wing, J.K., Babor, T., Brugha, T., Burke, J., Cooper, J.E., Giel, R., Jablenski, A., Regier, D. and Sartorius, N. (1990) SCAN: Schedules for clinical assessment in neuropsychiatry. Arch. Gen. Psychiatry, 47, 589-593.
35. World Health Organization (1998) In Wing, J.K., Sartorious, N. and Ustun, T.B (eds). Diagnosis and Clinical Measurement in Psychiatry. A Reference Manual for SCAN. World Health Organization, Geneva.
36. Celik, C. (2003) Computer Assisted Personal Interviewing Application for the Schedules for Clinical Assessment in Neuropsychiatry Version 2.1 and Diagnostic Algorithms for WHO ICD10 Chapter V DCR and for Statistical Manual IV. Release 1. Ed. 1.0.3.5. Win 9x NT. World Health Organization, Geneva.
37. Boehnke, M. and Cox, N.J. (1997) Accurate inference of relationships in sib-pair linkage studies. Am. J. Hum. Genet., 61, 423-429.
38. Abecasis, G.R., Cherny, S.S., Cookson, W.O. and Cardon, L.R. (2002) Merlin-rapid analysis of dense genetic maps using sparse gene flow trees. Nat. Genet., 30, 97-101.
39. Kong, A. and Cox, N.J. (1997) Allele-sharing models: LOD scores and accurate linkage tests. Am. J. Hum. Genet., 61, 1179-1188.
40. Greenberg, D.A., Abreu, P. and Hodge, S.E. (1998) The power to detect linkage in complex disease by means of simple LOD-score analyses. Am. J. Hum. Genet., 63, 870-879.
41. Kruglyak, L., Daly, M.J., Reeve-Daly, M.P. and Lander, E.S. (1996) Parametric and nonparametric linkage analysis: A unified multipoint approach. Am. J. Hum. Genet., 58, 1347-1363.
42. Feingold, E., Brown, P.O. and Siegmund, D. (1993). Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. Am. J. Hum. Genet., 53, 234-251.