Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation

Oncology Reports

Volumn 20, Issue 3, 2008, Pages 637-643

  Kang, Young Hee ^a   Lee, Su Jae ^a  

^a Hanyang University   (South Korea)

Author keywords

AIF release; Arsenic trioxide (As2O3); Bax translocaion; Bcl 2 phosphorylation; JNK; Mitochondrial membrane potential loss; p38 MAPK; ROS generation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ALPHA TUBULIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ARSENIC TRIOXIDE; BETA ACTIN; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; CASPASE; MAP3K8 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; ONCOPROTEIN; ORGANOARSENIC DERIVATIVE; OXIDE;

APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GAMMA IRRADIATION; HELA CELL; HUMAN; HUMAN CELL; IONIZING RADIATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; UTERINE CERVIX CANCER; CELL NUCLEUS; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; METABOLISM; MULTIMODALITY CANCER THERAPY; PATHOLOGY; PHOSPHORYLATION; PROTEIN TRANSPORT; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; UTERINE CERVIX TUMOR;

APOPTOSIS; ARSENICALS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL NUCLEUS; COMBINED MODALITY THERAPY; CYTOSOL; FEMALE; HELA CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDES; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION, IONIZING; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; UTERINE CERVICAL NEOPLASMS;

EID: 54549089948     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or_00000053     Document Type: Article

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