메뉴 건너뛰기




Volumn 4, Issue 12, 2005, Pages 1834-1841

The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53BP1 DNA binding activity

Author keywords

Arginine methylation; DNA damage foci; DNA repair; GAR motif; Methylarginine; 53BP1; PRMT1

Indexed keywords

ARGININE; BINDING PROTEIN; DOUBLE STRANDED DNA; GLYCINE; METHYLTRANSFERASE; METHYLTRANSFERASE INHIBITOR; P53 BINDING PROTEIN 1; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 29244456155     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.4.12.2250     Document Type: Article
Times cited : (112)

References (63)
  • 1
    • 0037178748 scopus 로고    scopus 로고
    • Interfaces between the detection, signaling, and repair of DNA damage
    • Rouse J, Jackson SP. Interfaces between the detection, signaling, and repair of DNA damage. Science 2002; 297:547-51.
    • (2002) Science , vol.297 , pp. 547-551
    • Rouse, J.1    Jackson, S.P.2
  • 2
    • 4644327092 scopus 로고    scopus 로고
    • Double strand break metabolism and cancer susceptibility: Lessons from the mre11 complex
    • Petrini JH, Theunissen JW. Double strand break metabolism and cancer susceptibility: Lessons from the mre11 complex. Cell Cycle 2004; 3:541-2.
    • (2004) Cell Cycle , vol.3 , pp. 541-542
    • Petrini, J.H.1    Theunissen, J.W.2
  • 3
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh, Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003; 3:155-68.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 4
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chtomatin domains involved in DNA double strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chtomatin domains involved in DNA double strand breaks in vivo. J Cell Biol 1999; 146:905-16.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 6
    • 3242885156 scopus 로고    scopus 로고
    • MDC1/NFBD1: A key regulator of the DNA damage response in higher eukaryotes
    • Stucki M, Jackson SP. MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes. DNA Repair 2004; 3:953-7.
    • (2004) DNA Repair , vol.3 , pp. 953-957
    • Stucki, M.1    Jackson, S.P.2
  • 7
    • 0030764691 scopus 로고    scopus 로고
    • hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double strand breaks
    • Maser RS, Monsen KJ, Nelms BE, Petrini, JH. hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double strand breaks. Mol Cell Biol 1997; 17:6087-96.
    • (1997) Mol Cell Biol , vol.17 , pp. 6087-6096
    • Maser, R.S.1    Monsen, K.J.2    Nelms, B.E.3    Petrini, J.H.4
  • 13
    • 0038391226 scopus 로고    scopus 로고
    • NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage
    • Peng A, Chen PL. NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage. J Biol Chem 2003; 278:8873-6.
    • (2003) J Biol Chem , vol.278 , pp. 8873-8876
    • Peng, A.1    Chen, P.L.2
  • 14
    • 0037424296 scopus 로고    scopus 로고
    • NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways
    • Xu X, Stern DF. NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. J Biol Chem 2003; 278:8795-8803.
    • (2003) J Biol Chem , vol.278 , pp. 8795-8803
    • Xu, X.1    Stern, D.F.2
  • 15
    • 0037458608 scopus 로고    scopus 로고
    • NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-ammo acid repeat sequence, is an early participant in DNA damage response
    • Shang YL, Bodero AJ, Chen PL. NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-ammo acid repeat sequence, is an early participant in DNA damage response. J Biol Chem 2003; 278:6323-9.
    • (2003) J Biol Chem , vol.278 , pp. 6323-6329
    • Shang, Y.L.1    Bodero, A.J.2    Chen, P.L.3
  • 16
    • 0037378527 scopus 로고    scopus 로고
    • p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice
    • Ward LM, Minn K, van Deursen J, Chen J. p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice. Mol Cell Biol 2003; 23:2556-63.
    • (2003) Mol Cell Biol , vol.23 , pp. 2556-2563
    • Ward, L.M.1    Minn, K.2    Van Deursen, J.3    Chen, J.4
  • 18
    • 0142186242 scopus 로고    scopus 로고
    • The MRN complex: Coordinating and mediating the response to broken chromosomes
    • van den Bosch M, Bree RT, Lowndes NF. The MRN complex: coordinating and mediating the response to broken chromosomes. EMBO Rep 2003; 4:844-9.
    • (2003) EMBO Rep , vol.4 , pp. 844-849
    • Van Den Bosch, M.1    Bree, R.T.2    Lowndes, N.F.3
  • 19
    • 19344371406 scopus 로고    scopus 로고
    • Mre11 assembles linear DNA fragments into DNA damage signaling complexes
    • Costanzo V, Paull TT, Gottesman M, Gautier J. Mre11 assembles linear DNA fragments into DNA damage signaling complexes. PLoS Biol 2004; 2:600-609.
    • (2004) PLoS Biol , vol.2 , pp. 600-609
    • Costanzo, V.1    Paull, T.T.2    Gottesman, M.3    Gautier, J.4
  • 20
    • 17644409069 scopus 로고    scopus 로고
    • ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
    • Lee JH, Paull TT. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science 2005; 308:551-4.
    • (2005) Science , vol.308 , pp. 551-554
    • Lee, J.H.1    Paull, T.T.2
  • 21
    • 1842431822 scopus 로고    scopus 로고
    • Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
    • Lee JH, Paull TT. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science 2004; 304:93-6.
    • (2004) Science , vol.304 , pp. 93-96
    • Lee, J.H.1    Paull, T.T.2
  • 28
    • 0142240342 scopus 로고    scopus 로고
    • BRCT repeats as phosphopeptide-binding modules involved in protein targeting
    • Manke IA, Lowery DM, Nguyen A, Yaffe MB. BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 2003; 302:636-9.
    • (2003) Science , vol.302 , pp. 636-639
    • Manke, I.A.1    Lowery, D.M.2    Nguyen, A.3    Yaffe, M.B.4
  • 29
    • 0035813227 scopus 로고    scopus 로고
    • Structure of the Rad50·Mre11 DNA Repair Complex from Saccharomyces cerevisiae by Electron Microscopy
    • Anderson DE, Trujillo KM, Sung P, Erickson HP. Structure of the Rad50·Mre11 DNA Repair Complex from Saccharomyces cerevisiae by Electron Microscopy. J Biol Chem 2001; 276:37027-33.
    • (2001) J Biol Chem , vol.276 , pp. 37027-37033
    • Anderson, D.E.1    Trujillo, K.M.2    Sung, P.3    Erickson, H.P.4
  • 30
    • 0035951850 scopus 로고    scopus 로고
    • Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1
    • Xia Z, Morales JC, Dunphy WG, Carpenter PB. Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1. J Biol Chem 2001; 276:2708-18.
    • (2001) J Biol Chem , vol.276 , pp. 2708-2718
    • Xia, Z.1    Morales, J.C.2    Dunphy, W.G.3    Carpenter, P.B.4
  • 31
    • 0035972194 scopus 로고    scopus 로고
    • Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways
    • Rappold, I, Iwabuchi, K, Date, T. and Chen, J. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. J Cell Biol 2001; 153:613-20.
    • (2001) J Cell Biol , vol.153 , pp. 613-620
    • Rappold, I.1    Iwabuchi, K.2    Date, T.3    Chen, J.4
  • 32
    • 0034739853 scopus 로고    scopus 로고
    • p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • Schultz LB, Chehab NH, Malikzay A, Halazonetis TD. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J Cell Biol 2000; 151:1381-90.
    • (2000) J Cell Biol , vol.151 , pp. 1381-1390
    • Schultz, L.B.1    Chehab, N.H.2    Malikzay, A.3    Halazonetis, T.D.4
  • 36
    • 25444502657 scopus 로고    scopus 로고
    • Artemis links ATM to Double Strand Break Rejoining
    • Jeggo PA, Löbrich M. Artemis links ATM to Double Strand Break Rejoining. Cell Cycle 2005; 4:359-362.
    • (2005) Cell Cycle , vol.4 , pp. 359-362
    • Jeggo, P.A.1    Löbrich, M.2
  • 39
    • 8844248619 scopus 로고    scopus 로고
    • Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage
    • Sanders SL, Portoso M, Mata J, Bahler J, Allshire RC, Kouzarides T Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 2004; 119:603-14.
    • (2004) Cell , vol.119 , pp. 603-614
    • Sanders, S.L.1    Portoso, M.2    Mata, J.3    Bahler, J.4    Allshire, R.C.5    Kouzarides, T.6
  • 40
    • 23344444863 scopus 로고    scopus 로고
    • Tudor domains bind symmetrical dimethylated arginines
    • Cote, J. & Richard, S. Tudor domains bind symmetrical dimethylated arginines. J Biol Chem 2005; 280:28476-83.
    • (2005) J Biol Chem , vol.280 , pp. 28476-28483
    • Cote, J.1    Richard, S.2
  • 41
    • 11244300690 scopus 로고    scopus 로고
    • hPTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionising radiation
    • Jowsey, PA, Doherty, A.J. and Rouse, J. hPTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionising radiation. J Biol Chem 2004; 279:55562-9.
    • (2004) J Biol Chem , vol.279 , pp. 55562-55569
    • Jowsey, P.A.1    Doherty, A.J.2    Rouse, J.3
  • 42
    • 20844450998 scopus 로고    scopus 로고
    • Arginine methylation: An emerging regulator of protein function
    • Bedford, M.T. & Richard, S. Arginine methylation: an emerging regulator of protein function. Mol Cell 2005; 18:263-72.
    • (2005) Mol Cell , vol.18 , pp. 263-272
    • Bedford, M.T.1    Richard, S.2
  • 43
    • 0031603283 scopus 로고    scopus 로고
    • RNA and protein interactions modulated by protein arginine methylation
    • Gary, J.D. & Clarke, S. RNA and protein interactions modulated by protein arginine methylation. Prog Nuc Acid Res Mol Biol 1998; 63:65-131.
    • (1998) Prog Nuc Acid Res Mol Biol , vol.63 , pp. 65-131
    • Gary, J.D.1    Clarke, S.2
  • 44
    • 17544370102 scopus 로고    scopus 로고
    • The mammalian immediate-early TIS21 protein and the leukemia-associated BTG1 protein interact with a protein-arginine N-methyltransferase
    • Lin WJ, Gary J, Yang, M.C, Clarke, S. & Herschman, H.R. The mammalian immediate-early TIS21 protein and the leukemia-associated BTG1 protein interact with a protein-arginine N-methyltransferase. J Biol Chem 1996; 271:15034-15044.
    • (1996) J Biol Chem , vol.271 , pp. 15034-15044
    • Lin, W.J.1    Gary, J.2    Yang, M.C.3    Clarke, S.4    Herschman, H.R.5
  • 45
    • 0032479171 scopus 로고    scopus 로고
    • PRMT3 a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation
    • Tang J, Kao PN, Herschman HR. PRMT3 a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation. J Biol Chem 1998; 273:16935-45.
    • (1998) J Biol Chem , vol.273 , pp. 16935-16945
    • Tang, J.1    Kao, P.N.2    Herschman, H.R.3
  • 46
    • 17044392996 scopus 로고    scopus 로고
    • Role of Protein Methylation in Regulation of Transcription
    • Lee DY, Teyssier C, Strahl BD, Stallcup MR. Role of Protein Methylation in Regulation of Transcription. Endocr Rev 2005; 26:147-170.
    • (2005) Endocr Rev , vol.26 , pp. 147-170
    • Lee, D.Y.1    Teyssier, C.2    Strahl, B.D.3    Stallcup, M.R.4
  • 48
    • 15444374342 scopus 로고    scopus 로고
    • Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control
    • Boisvert FM, Déry U, Masson JY, Richard S. Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control. Genes & Dev 2005; 19:671-6.
    • (2005) Genes & Dev , vol.19 , pp. 671-676
    • Boisvert, F.M.1    Déry, U.2    Masson, J.Y.3    Richard, S.4
  • 49
    • 25444445033 scopus 로고    scopus 로고
    • Methylation of MRE11 Regulates its Nuclear Compartmentalization
    • Boisvert FM, Hendzel MJ, Masson JY, Richard S. Methylation of MRE11 Regulates its Nuclear Compartmentalization. Cell Cycle 2005; 4:981-989.
    • (2005) Cell Cycle , vol.4 , pp. 981-989
    • Boisvert, F.M.1    Hendzel, M.J.2    Masson, J.Y.3    Richard, S.4
  • 50
    • 0037164866 scopus 로고    scopus 로고
    • Symmetrical dimethylargimne methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing
    • Boisvert FM, Côté J, Boulanger MC, Cléroux P, Bachand F, Autexier C, Richard S. Symmetrical dimethylargimne methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing. J Cell Biol 2002; 159:957-69.
    • (2002) J Cell Biol , vol.159 , pp. 957-969
    • Boisvert, F.M.1    Côté, J.2    Boulanger, M.C.3    Cléroux, P.4    Bachand, F.5    Autexier, C.6    Richard, S.7
  • 51
    • 0037244282 scopus 로고    scopus 로고
    • Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1
    • Côté J, Boisvert FM, Boulanger MC, Bedford MT, Richard S. Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1. Mol Biol Cell 2003; 14:274-87.
    • (2003) Mol Biol Cell , vol.14 , pp. 274-287
    • Côté, J.1    Boisvert, F.M.2    Boulanger, M.C.3    Bedford, M.T.4    Richard, S.5
  • 52
    • 0036150875 scopus 로고    scopus 로고
    • Kinetochore localisation of the DNA damage response component 53BP1 during mitosis
    • Jullien D, Vagnarelli P, Earnshaw WC, Adachi Y. Kinetochore localisation of the DNA damage response component 53BP1 during mitosis. J Cell Sci 2002; 115:71-79.
    • (2002) J Cell Sci , vol.115 , pp. 71-79
    • Jullien, D.1    Vagnarelli, P.2    Earnshaw, W.C.3    Adachi, Y.4
  • 54
    • 0033065488 scopus 로고    scopus 로고
    • Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3′-end formation
    • Valentini SR, Weiss VH, Silver PA. Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3′-end formation. RNA 1999; 5:272-280.
    • (1999) RNA , vol.5 , pp. 272-280
    • Valentini, S.R.1    Weiss, V.H.2    Silver, P.A.3
  • 55
    • 0028006282 scopus 로고
    • Enzymatic methylation of recombinant heterogeneous nuclear RNP protein A1. Dual substrate specificity for S-adenosylmethionine: Histone-arginine N-methyltransferase
    • Rajpurohit R, Lee SO, Park JO, Paik WK, Kim S. Enzymatic methylation of recombinant heterogeneous nuclear RNP protein A1. Dual substrate specificity for S-adenosylmethionine: histone-arginine N-methyltransferase. J Biol Chem 1994; 269:1075-82.
    • (1994) J Biol Chem , vol.269 , pp. 1075-1082
    • Rajpurohit, R.1    Lee, S.O.2    Park, J.O.3    Paik, W.K.4    Kim, S.5
  • 56
    • 0027141501 scopus 로고
    • The Gly/Arg-rich (GAR) domain of Xenopus nucleolin facilitates in vitro nucleic acid binding and in vivo nucleolar localization
    • Heine MA, Rankin ML, DiMario PJ. The Gly/Arg-rich (GAR) domain of Xenopus nucleolin facilitates in vitro nucleic acid binding and in vivo nucleolar localization. Mol Biol Cell. 1993;4:1189-204.
    • (1993) Mol Biol Cell , vol.4 , pp. 1189-1204
    • Heine, M.A.1    Rankin, M.L.2    DiMario, P.J.3
  • 57
    • 0028930155 scopus 로고
    • A nuclear localization domain in the hnRNP A1 protein
    • Siomi H, Dreyfuss G. A nuclear localization domain in the hnRNP A1 protein. J Cell Biol. 1995;129:551-60.
    • (1995) J Cell Biol , vol.129 , pp. 551-560
    • Siomi, H.1    Dreyfuss, G.2
  • 58
    • 0026740718 scopus 로고
    • Primary structure and binding activity of the hnRNP U protein: Binding RNA through RGG box
    • Kiledjian M, Dreyfuss G. Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. EMBO J. 1992;11:2655-64.
    • (1992) EMBO J , vol.11 , pp. 2655-2664
    • Kiledjian, M.1    Dreyfuss, G.2
  • 59
    • 0029795035 scopus 로고    scopus 로고
    • The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation
    • Mears WE, Rice SA. The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation. J Virol. 1996;70:7445-53.
    • (1996) J Virol , vol.70 , pp. 7445-7453
    • Mears, W.E.1    Rice, S.A.2
  • 60
    • 0035171131 scopus 로고    scopus 로고
    • Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B′ and the Sm-like protein LSm4, and their interaction with the SMN protein
    • Brahms H, Meheus L, de Brabandere V, Fischer U, Luhrmann R. Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B′ and the Sm-like protein LSm4, and their interaction with the SMN protein. RNA 2001; 7:1531-42.
    • (2001) RNA , vol.7 , pp. 1531-1542
    • Brahms, H.1    Meheus, L.2    De Brabandere, V.3    Fischer, U.4    Luhrmann, R.5
  • 61
    • 0035947239 scopus 로고    scopus 로고
    • SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets
    • Friesen WJ, Massenet S, Paushkin S, Wyce A, Dreyfuss G. SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets. Mol Cell 2001; 7:1111-7.
    • (2001) Mol Cell , vol.7 , pp. 1111-1117
    • Friesen, W.J.1    Massenet, S.2    Paushkin, S.3    Wyce, A.4    Dreyfuss, G.5
  • 62
    • 0036845335 scopus 로고    scopus 로고
    • Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs
    • Meister G, Fischer U. Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs. EMBO J 2002; 21:5853-63.
    • (2002) EMBO J , vol.21 , pp. 5853-5863
    • Meister, G.1    Fischer, U.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.