-
1
-
-
0041520529
-
Structure of the semaphorin-3A receptor binding module
-
Antipenko A., Himanen J.P., van Leyen K., Nardi-Dei V., Lesniak J., Barton W.A., Rajashankar K.R., Lu M., Hoemme C., Puschel A.W., Nikolov D.B. Structure of the semaphorin-3A receptor binding module. Neuron 2003, 39:589-598.
-
(2003)
Neuron
, vol.39
, pp. 589-598
-
-
Antipenko, A.1
Himanen, J.P.2
van Leyen, K.3
Nardi-Dei, V.4
Lesniak, J.5
Barton, W.A.6
Rajashankar, K.R.7
Lu, M.8
Hoemme, C.9
Puschel, A.W.10
Nikolov, D.B.11
-
2
-
-
34547749466
-
C-Met ectodomain shedding rate correlates with malignant potential
-
Athauda G., Giubellino A., Coleman J.A., Horak C., Steeg P.S., Lee M.J., Trepel J., Wimberly J., Sun J., Coxon A., Burgess T.L., Bottaro D.P. c-Met ectodomain shedding rate correlates with malignant potential. Clin. Cancer Res. 2006, 12:4154-4162.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 4154-4162
-
-
Athauda, G.1
Giubellino, A.2
Coleman, J.A.3
Horak, C.4
Steeg, P.S.5
Lee, M.J.6
Trepel, J.7
Wimberly, J.8
Sun, J.9
Coxon, A.10
Burgess, T.L.11
Bottaro, D.P.12
-
3
-
-
77956927514
-
Integrin receptors play a role in the internalin B-dependent entry of Listeria monocytogenes into host cells
-
Auriemma C., Viscardi M., Tafuri S., Pavone L.M., Capuano F., Rinaldi L., Della Morte R., Iovane G., Staiano N. Integrin receptors play a role in the internalin B-dependent entry of Listeria monocytogenes into host cells. Cell. Mol. Biol. Lett. 2010, 15:496-506.
-
(2010)
Cell. Mol. Biol. Lett.
, vol.15
, pp. 496-506
-
-
Auriemma, C.1
Viscardi, M.2
Tafuri, S.3
Pavone, L.M.4
Capuano, F.5
Rinaldi, L.6
Della Morte, R.7
Iovane, G.8
Staiano, N.9
-
4
-
-
1542666874
-
GW domains of the Listeria monocytogenes invasion protein InlB are required for potentiation of Met activation
-
Banerjee M., Copp J., Vuga D., Marino M., Chapman T., van der Geer P., Ghosh P. GW domains of the Listeria monocytogenes invasion protein InlB are required for potentiation of Met activation. Mol. Microbiol. 2004, 52:257-271.
-
(2004)
Mol. Microbiol.
, vol.52
, pp. 257-271
-
-
Banerjee, M.1
Copp, J.2
Vuga, D.3
Marino, M.4
Chapman, T.5
van der Geer, P.6
Ghosh, P.7
-
5
-
-
0030932842
-
Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1
-
Barleon B., Totzke F., Herzog C., Blanke S., Kremmer E., Siemeister G., Marme D., Martiny-Baron G. Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1. J. Biol. Chem. 1997, 272:10382-10388.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10382-10388
-
-
Barleon, B.1
Totzke, F.2
Herzog, C.3
Blanke, S.4
Kremmer, E.5
Siemeister, G.6
Marme, D.7
Martiny-Baron, G.8
-
6
-
-
51049117095
-
A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met
-
Basilico C., Arnesano A., Galluzzo M., Comoglio P.M., Michieli P. A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met. J. Biol. Chem. 2008, 283:21267-21277.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 21267-21277
-
-
Basilico, C.1
Arnesano, A.2
Galluzzo, M.3
Comoglio, P.M.4
Michieli, P.5
-
7
-
-
34848855124
-
The MET receptor tyrosine kinase in invasion and metastasis
-
Benvenuti S., Comoglio P.M. The MET receptor tyrosine kinase in invasion and metastasis. J. Cell. Physiol. 2007, 213:316-325.
-
(2007)
J. Cell. Physiol.
, vol.213
, pp. 316-325
-
-
Benvenuti, S.1
Comoglio, P.M.2
-
8
-
-
34548491198
-
Internalins: a complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes
-
Bierne H., Sabet C., Personnic N., Cossart P. Internalins: a complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes. Microbes Infect. 2007, 9:1156-1166.
-
(2007)
Microbes Infect.
, vol.9
, pp. 1156-1166
-
-
Bierne, H.1
Sabet, C.2
Personnic, N.3
Cossart, P.4
-
9
-
-
0345601083
-
Met, metastasis, motility and more
-
Birchmeier C., Birchmeier W., Gherardi E., Vande Woude G.F. Met, metastasis, motility and more. Nat. Rev. Mol. Cell Biol. 2003, 4:915-925.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
Birchmeier, W.2
Gherardi, E.3
Vande Woude, G.F.4
-
10
-
-
0032189977
-
Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
-
Birchmeier C., Gherardi E. Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol. 1998, 8:404-410.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 404-410
-
-
Birchmeier, C.1
Gherardi, E.2
-
11
-
-
0028890689
-
The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction
-
Blechman J.M., Lev S., Barg J., Eisenstein M., Vaks B., Vogel Z., Givol D., Yarden Y. The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction. Cell 1995, 80:103-113.
-
(1995)
Cell
, vol.80
, pp. 103-113
-
-
Blechman, J.M.1
Lev, S.2
Barg, J.3
Eisenstein, M.4
Vaks, B.5
Vogel, Z.6
Givol, D.7
Yarden, Y.8
-
12
-
-
33746504571
-
Invasive growth: a MET-driven genetic programme for cancer and stem cells
-
Boccaccio C., Comoglio P.M. Invasive growth: a MET-driven genetic programme for cancer and stem cells. Nat. Rev. Cancer 2006, 6:637-645.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 637-645
-
-
Boccaccio, C.1
Comoglio, P.M.2
-
13
-
-
24144443283
-
MET meet adaptors: functional and structural implications in downstream signalling mediated by the Met receptor
-
Bolanos-Garcia V.M. MET meet adaptors: functional and structural implications in downstream signalling mediated by the Met receptor. Mol. Cell. Biochem. 2005, 276:149-157.
-
(2005)
Mol. Cell. Biochem.
, vol.276
, pp. 149-157
-
-
Bolanos-Garcia, V.M.1
-
14
-
-
0001290687
-
Domains in plexins: links to integrins and transcription factors
-
Bork P., Doerks T., Springer T.A., Snel B. Domains in plexins: links to integrins and transcription factors. Trends Biochem. Sci. 1999, 24:261-263.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 261-263
-
-
Bork, P.1
Doerks, T.2
Springer, T.A.3
Snel, B.4
-
15
-
-
3242663197
-
Met provides essential signals for liver regeneration
-
Borowiak M., Garratt A.N., Wustefeld T., Strehle M., Trautwein C., Birchmeier C. Met provides essential signals for liver regeneration. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:10608-10613.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10608-10613
-
-
Borowiak, M.1
Garratt, A.N.2
Wustefeld, T.3
Strehle, M.4
Trautwein, C.5
Birchmeier, C.6
-
16
-
-
0025805633
-
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
-
Bottaro D.P., Rubin J.S., Faletto D.L., Chan A.M., Kmiecik T.E., Vande Woude G.F., Aaronson S.A. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 1991, 251:802-804.
-
(1991)
Science
, vol.251
, pp. 802-804
-
-
Bottaro, D.P.1
Rubin, J.S.2
Faletto, D.L.3
Chan, A.M.4
Kmiecik, T.E.5
Vande Woude, G.F.6
Aaronson, S.A.7
-
17
-
-
0030608784
-
InlB: an invasion protein of Listeria monocytogenes with a novel type of surface association
-
Braun L., Dramsi S., Dehoux P., Bierne H., Lindahl G., Cossart P. InlB: an invasion protein of Listeria monocytogenes with a novel type of surface association. Mol. Microbiol. 1997, 25:285-294.
-
(1997)
Mol. Microbiol.
, vol.25
, pp. 285-294
-
-
Braun, L.1
Dramsi, S.2
Dehoux, P.3
Bierne, H.4
Lindahl, G.5
Cossart, P.6
-
18
-
-
0034599782
-
GC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes
-
Braun L., Ghebrehiwet B., Cossart P. gC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes. EMBO J. 2000, 19:1458-1466.
-
(2000)
EMBO J.
, vol.19
, pp. 1458-1466
-
-
Braun, L.1
Ghebrehiwet, B.2
Cossart, P.3
-
19
-
-
10744230127
-
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors
-
Burgess A.W., Cho H.S., Eigenbrot C., Ferguson K.M., Garrett T.P., Leahy D.J., Lemmon M.A., Sliwkowski M.X., Ward C.W., Yokoyama S. An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. Mol. Cell 2003, 12:541-552.
-
(2003)
Mol. Cell
, vol.12
, pp. 541-552
-
-
Burgess, A.W.1
Cho, H.S.2
Eigenbrot, C.3
Ferguson, K.M.4
Garrett, T.P.5
Leahy, D.J.6
Lemmon, M.A.7
Sliwkowski, M.X.8
Ward, C.W.9
Yokoyama, S.10
-
20
-
-
52449098259
-
Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis
-
Cassano M., Biressi S., Finan A., Benedetti L., Omes C., Boratto R., Martin F., Allegretti M., Broccoli V., Cusella De Angelis G., Comoglio P.M., Basilico C., Torrente Y., Michieli P., Cossu G., Sampaolesi M. Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis. PLoS One 2008, 3:e3223.
-
(2008)
PLoS One
, vol.3
-
-
Cassano, M.1
Biressi, S.2
Finan, A.3
Benedetti, L.4
Omes, C.5
Boratto, R.6
Martin, F.7
Allegretti, M.8
Broccoli, V.9
Cusella De Angelis, G.10
Comoglio, P.M.11
Basilico, C.12
Torrente, Y.13
Michieli, P.14
Cossu, G.15
Sampaolesi, M.16
-
21
-
-
0026320865
-
Identification of a competitive HGF antagonist encoded by an alternative transcript
-
Chan A.M., Rubin J.S., Bottaro D.P., Hirschfield D.W., Chedid M., Aaronson S.A. Identification of a competitive HGF antagonist encoded by an alternative transcript. Science 1991, 254:1382-1385.
-
(1991)
Science
, vol.254
, pp. 1382-1385
-
-
Chan, A.M.1
Rubin, J.S.2
Bottaro, D.P.3
Hirschfield, D.W.4
Chedid, M.5
Aaronson, S.A.6
-
22
-
-
0032957467
-
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding
-
Chirgadze D.Y., Hepple J.P., Zhou H., Byrd R.A., Blundell T.L., Gherardi E. Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding. Nat. Struct. Biol. 1999, 6:72-79.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 72-79
-
-
Chirgadze, D.Y.1
Hepple, J.P.2
Zhou, H.3
Byrd, R.A.4
Blundell, T.L.5
Gherardi, E.6
-
23
-
-
34247142787
-
C-Met is essential for wound healing in the skin
-
Chmielowiec J., Borowiak M., Morkel M., Stradal T., Munz B., Werner S., Wehland J., Birchmeier C., Birchmeier W. c-Met is essential for wound healing in the skin. J. Cell Biol. 2007, 177:151-162.
-
(2007)
J. Cell Biol.
, vol.177
, pp. 151-162
-
-
Chmielowiec, J.1
Borowiak, M.2
Morkel, M.3
Stradal, T.4
Munz, B.5
Werner, S.6
Wehland, J.7
Birchmeier, C.8
Birchmeier, W.9
-
24
-
-
0037162799
-
Structure of the extracellular region of HER3 reveals an interdomain tether
-
Cho H.S., Leahy D.J. Structure of the extracellular region of HER3 reveals an interdomain tether. Science 2002, 297:1330-1333.
-
(2002)
Science
, vol.297
, pp. 1330-1333
-
-
Cho, H.S.1
Leahy, D.J.2
-
25
-
-
15844393132
-
Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity
-
Cioce V., Csaky K.G., Chan A.M., Bottaro D.P., Taylor W.G., Jensen R., Aaronson S.A., Rubin J.S. Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity. J. Biol. Chem. 1996, 271:13110-13115.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13110-13115
-
-
Cioce, V.1
Csaky, K.G.2
Chan, A.M.3
Bottaro, D.P.4
Taylor, W.G.5
Jensen, R.6
Aaronson, S.A.7
Rubin, J.S.8
-
26
-
-
0021241398
-
Molecular cloning of a new transforming gene from a chemically transformed human cell line
-
Cooper C.S., Park M., Blair D.G., Tainsky M.A., Huebner K., Croce C.M., Vande Woude G.F. Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature 1984, 311:29-33.
-
(1984)
Nature
, vol.311
, pp. 29-33
-
-
Cooper, C.S.1
Park, M.2
Blair, D.G.3
Tainsky, M.A.4
Huebner, K.5
Croce, C.M.6
Vande Woude, G.F.7
-
27
-
-
0037424230
-
Multiple regions of internalin B contribute to its ability to turn on the Ras-mitogen-activated protein kinase pathway
-
Copp J., Marino M., Banerjee M., Ghosh P., van der Geer P. Multiple regions of internalin B contribute to its ability to turn on the Ras-mitogen-activated protein kinase pathway. J. Biol. Chem. 2003, 278:7783-7789.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7783-7789
-
-
Copp, J.1
Marino, M.2
Banerjee, M.3
Ghosh, P.4
van der Geer, P.5
-
28
-
-
0028110068
-
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity
-
Davis S., Gale N.W., Aldrich T.H., Maisonpierre P.C., Lhotak V., Pawson T., Goldfarb M., Yancopoulos G.D. Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. Science 1994, 266:816-819.
-
(1994)
Science
, vol.266
, pp. 816-819
-
-
Davis, S.1
Gale, N.W.2
Aldrich, T.H.3
Maisonpierre, P.C.4
Lhotak, V.5
Pawson, T.6
Goldfarb, M.7
Yancopoulos, G.D.8
-
29
-
-
0022387730
-
The human met oncogene is related to the tyrosine kinase oncogenes
-
Dean M., Park M., Le Beau M.M., Robins T.S., Diaz M.O., Rowley J.D., Blair D.G., Vande Woude G.F. The human met oncogene is related to the tyrosine kinase oncogenes. Nature 1985, 318:385-388.
-
(1985)
Nature
, vol.318
, pp. 385-388
-
-
Dean, M.1
Park, M.2
Le Beau, M.M.3
Robins, T.S.4
Diaz, M.O.5
Rowley, J.D.6
Blair, D.G.7
Vande Woude, G.F.8
-
30
-
-
77958102573
-
CD44-independent activation of the Met signaling pathway by HGF and InlB
-
Dortet L., Veiga E., Bonazzi M., Cossart P. CD44-independent activation of the Met signaling pathway by HGF and InlB. Microbes Infect. 2010, 12:919-927.
-
(2010)
Microbes Infect.
, vol.12
, pp. 919-927
-
-
Dortet, L.1
Veiga, E.2
Bonazzi, M.3
Cossart, P.4
-
31
-
-
65249122512
-
Novel therapeutic inhibitors of the c-Met signaling pathway in cancer
-
Eder J.P., Vande Woude G.F., Boerner S.A., LoRusso P.M. Novel therapeutic inhibitors of the c-Met signaling pathway in cancer. Clin. Cancer Res. 2009, 15:2207-2214.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 2207-2214
-
-
Eder, J.P.1
Vande Woude, G.F.2
Boerner, S.A.3
LoRusso, P.M.4
-
32
-
-
48249158391
-
Structure-based view of epidermal growth factor receptor regulation
-
Ferguson K.M. Structure-based view of epidermal growth factor receptor regulation. Annu. Rev. Biophys. 2008, 37:353-373.
-
(2008)
Annu. Rev. Biophys.
, vol.37
, pp. 353-373
-
-
Ferguson, K.M.1
-
33
-
-
0037291769
-
EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization
-
Ferguson K.M., Berger M.B., Mendrola J.M., Cho H.S., Leahy D.J., Lemmon M.A. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol. Cell 2003, 11:507-517.
-
(2003)
Mol. Cell
, vol.11
, pp. 507-517
-
-
Ferguson, K.M.1
Berger, M.B.2
Mendrola, J.M.3
Cho, H.S.4
Leahy, D.J.5
Lemmon, M.A.6
-
34
-
-
73249142243
-
Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB
-
Ferraris D.M., Gherardi E., Di Y., Heinz D.W., Niemann H.H. Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB. J. Mol. Biol. 2010, 395:522-532.
-
(2010)
J. Mol. Biol.
, vol.395
, pp. 522-532
-
-
Ferraris, D.M.1
Gherardi, E.2
Di, Y.3
Heinz, D.W.4
Niemann, H.H.5
-
35
-
-
0034693753
-
Met receptor tyrosine kinase: enhanced signaling through adapter proteins
-
Furge K.A., Zhang Y.W., Vande Woude G.F. Met receptor tyrosine kinase: enhanced signaling through adapter proteins. Oncogene 2000, 19:5582-5589.
-
(2000)
Oncogene
, vol.19
, pp. 5582-5589
-
-
Furge, K.A.1
Zhang, Y.W.2
Vande Woude, G.F.3
-
36
-
-
18644370411
-
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha
-
Garrett T.P., McKern N.M., Lou M., Elleman T.C., Adams T.E., Lovrecz G.O., Zhu H.J., Walker F., Frenkel M.J., Hoyne P.A., Jorissen R.N., Nice E.C., Burgess A.W., Ward C.W. Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell 2002, 110:763-773.
-
(2002)
Cell
, vol.110
, pp. 763-773
-
-
Garrett, T.P.1
McKern, N.M.2
Lou, M.3
Elleman, T.C.4
Adams, T.E.5
Lovrecz, G.O.6
Zhu, H.J.7
Walker, F.8
Frenkel, M.J.9
Hoyne, P.A.10
Jorissen, R.N.11
Nice, E.C.12
Burgess, A.W.13
Ward, C.W.14
-
37
-
-
33645235265
-
Structural basis of hepatocyte growth factor/scatter factor and MET signalling
-
Gherardi E., Sandin S., Petoukhov M.V., Finch J., Youles M.E., Ofverstedt L.G., Miguel R.N., Blundell T.L., Vande Woude G.F., Skoglund U., Svergun D.I. Structural basis of hepatocyte growth factor/scatter factor and MET signalling. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:4046-4051.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 4046-4051
-
-
Gherardi, E.1
Sandin, S.2
Petoukhov, M.V.3
Finch, J.4
Youles, M.E.5
Ofverstedt, L.G.6
Miguel, R.N.7
Blundell, T.L.8
Vande Woude, G.F.9
Skoglund, U.10
Svergun, D.I.11
-
38
-
-
0142091400
-
Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor
-
Gherardi E., Youles M.E., Miguel R.N., Blundell T.L., Iamele L., Gough J., Bandyopadhyay A., Hartmann G., Butler P.J. Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:12039-12044.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 12039-12044
-
-
Gherardi, E.1
Youles, M.E.2
Miguel, R.N.3
Blundell, T.L.4
Iamele, L.5
Gough, J.6
Bandyopadhyay, A.7
Hartmann, G.8
Butler, P.J.9
-
39
-
-
0024430120
-
Biosynthesis of the protein encoded by the c-met proto-oncogene
-
Giordano S., Di Renzo M.F., Narsimhan R.P., Cooper C.S., Rosa C., Comoglio P.M. Biosynthesis of the protein encoded by the c-met proto-oncogene. Oncogene 1989, 4:1383-1388.
-
(1989)
Oncogene
, vol.4
, pp. 1383-1388
-
-
Giordano, S.1
Di Renzo, M.F.2
Narsimhan, R.P.3
Cooper, C.S.4
Rosa, C.5
Comoglio, P.M.6
-
40
-
-
66149095761
-
Decorin is a novel antagonistic ligand of the Met receptor
-
Goldoni S., Humphries A., Nystrom A., Sattar S., Owens R.T., McQuillan D.J., Ireton K., Iozzo R.V. Decorin is a novel antagonistic ligand of the Met receptor. J. Cell Biol. 2009, 185:743-754.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 743-754
-
-
Goldoni, S.1
Humphries, A.2
Nystrom, A.3
Sattar, S.4
Owens, R.T.5
McQuillan, D.J.6
Ireton, K.7
Iozzo, R.V.8
-
42
-
-
0026485023
-
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis
-
Hartmann G., Naldini L., Weidner K.M., Sachs M., Vigna E., Comoglio P.M., Birchmeier W. A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. Proc. Natl. Acad. Sci. U.S.A. 1992, 89:11574-11578.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 11574-11578
-
-
Hartmann, G.1
Naldini, L.2
Weidner, K.M.3
Sachs, M.4
Vigna, E.5
Comoglio, P.M.6
Birchmeier, W.7
-
43
-
-
13144295030
-
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo
-
Hartmann G., Prospero T., Brinkmann V., Ozcelik C., Winter G., Hepple J., Batley S., Bladt F., Sachs M., Birchmeier C., Birchmeier W., Gherardi E. Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo. Curr. Biol. 1998, 8:125-134.
-
(1998)
Curr. Biol.
, vol.8
, pp. 125-134
-
-
Hartmann, G.1
Prospero, T.2
Brinkmann, V.3
Ozcelik, C.4
Winter, G.5
Hepple, J.6
Batley, S.7
Bladt, F.8
Sachs, M.9
Birchmeier, C.10
Birchmeier, W.11
Gherardi, E.12
-
44
-
-
0035924322
-
Crystal structure of an Eph receptor-ephrin complex
-
Himanen J.P., Rajashankar K.R., Lackmann M., Cowan C.A., Henkemeyer M., Nikolov D.B. Crystal structure of an Eph receptor-ephrin complex. Nature 2001, 414:933-938.
-
(2001)
Nature
, vol.414
, pp. 933-938
-
-
Himanen, J.P.1
Rajashankar, K.R.2
Lackmann, M.3
Cowan, C.A.4
Henkemeyer, M.5
Nikolov, D.B.6
-
45
-
-
77954627688
-
Architecture of Eph receptor clusters
-
Himanen J.P., Yermekbayeva L., Janes P.W., Walker J.R., Xu K., Atapattu L., Rajashankar K.R., Mensinga A., Lackmann M., Nikolov D.B., Dhe-Paganon S. Architecture of Eph receptor clusters. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:10860-10865.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 10860-10865
-
-
Himanen, J.P.1
Yermekbayeva, L.2
Janes, P.W.3
Walker, J.R.4
Xu, K.5
Atapattu, L.6
Rajashankar, K.R.7
Mensinga, A.8
Lackmann, M.9
Nikolov, D.B.10
Dhe-Paganon, S.11
-
46
-
-
33847152551
-
Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains
-
Holmes O., Pillozzi S., Deakin J.A., Carafoli F., Kemp L., Butler P.J., Lyon M., Gherardi E. Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains. J. Mol. Biol. 2007, 367:395-408.
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 395-408
-
-
Holmes, O.1
Pillozzi, S.2
Deakin, J.A.3
Carafoli, F.4
Kemp, L.5
Butler, P.J.6
Lyon, M.7
Gherardi, E.8
-
47
-
-
1842428601
-
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
-
Huh C.G., Factor V.M., Sanchez A., Uchida K., Conner E.A., Thorgeirsson S.S. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:4477-4482.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 4477-4482
-
-
Huh, C.G.1
Factor, V.M.2
Sanchez, A.3
Uchida, K.4
Conner, E.A.5
Thorgeirsson, S.S.6
-
48
-
-
0031911137
-
NK1, a natural splice variant of hepatocyte growth factor/scatter factor, is a partial agonist in vivo
-
Jakubczak J.L., LaRochelle W.J., Merlino G. NK1, a natural splice variant of hepatocyte growth factor/scatter factor, is a partial agonist in vivo. Mol. Cell. Biol. 1998, 18:1275-1283.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1275-1283
-
-
Jakubczak, J.L.1
LaRochelle, W.J.2
Merlino, G.3
-
49
-
-
0036226347
-
Novel sequences propel familiar folds
-
Jawad Z., Paoli M. Novel sequences propel familiar folds. Structure 2002, 10:447-454.
-
(2002)
Structure
, vol.10
, pp. 447-454
-
-
Jawad, Z.1
Paoli, M.2
-
50
-
-
0033404562
-
Interaction between the protein InlB of Listeria monocytogenes and lipoteichoic acid: a novel mechanism of protein association at the surface of gram-positive bacteria
-
Jonquieres R., Bierne H., Fiedler F., Gounon P., Cossart P. Interaction between the protein InlB of Listeria monocytogenes and lipoteichoic acid: a novel mechanism of protein association at the surface of gram-positive bacteria. Mol. Microbiol. 1999, 34:902-914.
-
(1999)
Mol. Microbiol.
, vol.34
, pp. 902-914
-
-
Jonquieres, R.1
Bierne, H.2
Fiedler, F.3
Gounon, P.4
Cossart, P.5
-
51
-
-
0035171383
-
Synergy between the N- and C-terminal domains of InlB for efficient invasion of non-phagocytic cells by Listeria monocytogenes
-
Jonquieres R., Pizarro-Cerda J., Cossart P. Synergy between the N- and C-terminal domains of InlB for efficient invasion of non-phagocytic cells by Listeria monocytogenes. Mol. Microbiol. 2001, 42:955-965.
-
(2001)
Mol. Microbiol.
, vol.42
, pp. 955-965
-
-
Jonquieres, R.1
Pizarro-Cerda, J.2
Cossart, P.3
-
52
-
-
65949109051
-
Involvement of CD44v6 in InlB-dependent Listeria invasion
-
Jung C., Matzke A., Niemann H.H., Schwerk C., Tenenbaum T., Orian-Rousseau V. Involvement of CD44v6 in InlB-dependent Listeria invasion. Mol. Microbiol. 2009, 72:1196-1207.
-
(2009)
Mol. Microbiol.
, vol.72
, pp. 1196-1207
-
-
Jung, C.1
Matzke, A.2
Niemann, H.H.3
Schwerk, C.4
Tenenbaum, T.5
Orian-Rousseau, V.6
-
53
-
-
67549145398
-
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment
-
Jura N., Endres N.F., Engel K., Deindl S., Das R., Lamers M.H., Wemmer D.E., Zhang X., Kuriyan J. Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell 2009, 137:1293-1307.
-
(2009)
Cell
, vol.137
, pp. 1293-1307
-
-
Jura, N.1
Endres, N.F.2
Engel, K.3
Deindl, S.4
Das, R.5
Lamers, M.H.6
Wemmer, D.E.7
Zhang, X.8
Kuriyan, J.9
-
54
-
-
33745443328
-
Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors
-
Kemp L.E., Mulloy B., Gherardi E. Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors. Biochem. Soc. Trans. 2006, 34:414-417.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 414-417
-
-
Kemp, L.E.1
Mulloy, B.2
Gherardi, E.3
-
55
-
-
34248335027
-
Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist
-
Kirchhofer D., Lipari M.T., Santell L., Billeci K.L., Maun H.R., Sandoval W.N., Moran P., Ridgway J., Eigenbrot C., Lazarus R.A. Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:5306-5311.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 5306-5311
-
-
Kirchhofer, D.1
Lipari, M.T.2
Santell, L.3
Billeci, K.L.4
Maun, H.R.5
Sandoval, W.N.6
Moran, P.7
Ridgway, J.8
Eigenbrot, C.9
Lazarus, R.A.10
-
56
-
-
24644472051
-
CD151 forms a functional complex with c-Met in human salivary gland cancer cells
-
Klosek S.K., Nakashiro K., Hara S., Shintani S., Hasegawa H., Hamakawa H. CD151 forms a functional complex with c-Met in human salivary gland cancer cells. Biochem. Biophys. Res. Commun. 2005, 336:408-416.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.336
, pp. 408-416
-
-
Klosek, S.K.1
Nakashiro, K.2
Hara, S.3
Shintani, S.4
Hasegawa, H.5
Hamakawa, H.6
-
57
-
-
0030596012
-
Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A
-
Kobe B., Deisenhofer J. Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A. J. Mol. Biol. 1996, 264:1028-1043.
-
(1996)
J. Mol. Biol.
, vol.264
, pp. 1028-1043
-
-
Kobe, B.1
Deisenhofer, J.2
-
58
-
-
3142619403
-
The Sema domain of Met is necessary for receptor dimerization and activation
-
Kong-Beltran M., Stamos J., Wickramasinghe D. The Sema domain of Met is necessary for receptor dimerization and activation. Cancer Cell 2004, 6:75-84.
-
(2004)
Cancer Cell
, vol.6
, pp. 75-84
-
-
Kong-Beltran, M.1
Stamos, J.2
Wickramasinghe, D.3
-
59
-
-
3543004714
-
Insights into function of PSI domains from structure of the Met receptor PSI domain
-
Kozlov G., Perreault A., Schrag J.D., Park M., Cygler M., Gehring K., Ekiel I. Insights into function of PSI domains from structure of the Met receptor PSI domain. Biochem. Biophys. Res. Commun. 2004, 321:234-240.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.321
, pp. 234-240
-
-
Kozlov, G.1
Perreault, A.2
Schrag, J.D.3
Park, M.4
Cygler, M.5
Gehring, K.6
Ekiel, I.7
-
61
-
-
1442357192
-
HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma
-
Lai J.P., Chien J., Strome S.E., Staub J., Montoya D.P., Greene E.L., Smith D.I., Roberts L.R., Shridhar V. HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma. Oncogene 2004, 23:1439-1447.
-
(2004)
Oncogene
, vol.23
, pp. 1439-1447
-
-
Lai, J.P.1
Chien, J.2
Strome, S.E.3
Staub, J.4
Montoya, D.P.5
Greene, E.L.6
Smith, D.I.7
Roberts, L.R.8
Shridhar, V.9
-
62
-
-
34447535561
-
A new twist in the transmembrane signaling tool-kit
-
Lemmon M.A., Ferguson K.M. A new twist in the transmembrane signaling tool-kit. Cell 2007, 130:213-215.
-
(2007)
Cell
, vol.130
, pp. 213-215
-
-
Lemmon, M.A.1
Ferguson, K.M.2
-
63
-
-
33646889068
-
Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies
-
Li E., Hristova K. Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies. Biochemistry 2006, 45:6241-6251.
-
(2006)
Biochemistry
, vol.45
, pp. 6241-6251
-
-
Li, E.1
Hristova, K.2
-
64
-
-
0035887033
-
Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor
-
Lietha D., Chirgadze D.Y., Mulloy B., Blundell T.L., Gherardi E. Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. EMBO J. 2001, 20:5543-5555.
-
(2001)
EMBO J.
, vol.20
, pp. 5543-5555
-
-
Lietha, D.1
Chirgadze, D.Y.2
Mulloy, B.3
Blundell, T.L.4
Gherardi, E.5
-
65
-
-
45849138098
-
Listeria monocytogenes internalins bind to the human intestinal mucin MUC2
-
Linden S.K., Bierne H., Sabet C., Png C.W., Florin T.H., McGuckin M.A., Cossart P. Listeria monocytogenes internalins bind to the human intestinal mucin MUC2. Arch. Microbiol. 2008, 190:101-104.
-
(2008)
Arch. Microbiol.
, vol.190
, pp. 101-104
-
-
Linden, S.K.1
Bierne, H.2
Sabet, C.3
Png, C.W.4
Florin, T.H.5
McGuckin, M.A.6
Cossart, P.7
-
66
-
-
21144458217
-
Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function
-
Linke A., Muller P., Nurzynska D., Casarsa C., Torella D., Nascimbene A., Castaldo C., Cascapera S., Bohm M., Quaini F., Urbanek K., Leri A., Hintze T.H., Kajstura J., Anversa P. Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:8966-8971.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 8966-8971
-
-
Linke, A.1
Muller, P.2
Nurzynska, D.3
Casarsa, C.4
Torella, D.5
Nascimbene, A.6
Castaldo, C.7
Cascapera, S.8
Bohm, M.9
Quaini, F.10
Urbanek, K.11
Leri, A.12
Hintze, T.H.13
Kajstura, J.14
Anversa, P.15
-
67
-
-
33846987130
-
Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases
-
Liu H., Chen X., Focia P.J., He X. Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases. EMBO J. 2007, 26:891-901.
-
(2007)
EMBO J.
, vol.26
, pp. 891-901
-
-
Liu, H.1
Chen, X.2
Focia, P.J.3
He, X.4
-
68
-
-
0027260460
-
Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1
-
Lokker N.A., Godowski P.J. Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1. J. Biol. Chem. 1993, 268:17145-17150.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17145-17150
-
-
Lokker, N.A.1
Godowski, P.J.2
-
69
-
-
0026734672
-
Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding
-
Lokker N.A., Mark M.R., Luis E.A., Bennett G.L., Robbins K.A., Baker J.B., Godowski P.J. Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding. EMBO J. 1992, 11:2503-2510.
-
(1992)
EMBO J.
, vol.11
, pp. 2503-2510
-
-
Lokker, N.A.1
Mark, M.R.2
Luis, E.A.3
Bennett, G.L.4
Robbins, K.A.5
Baker, J.B.6
Godowski, P.J.7
-
70
-
-
0028177817
-
Mutational analysis and molecular modeling of the N-terminal kringle-containing domain of hepatocyte growth factor identifies amino acid side chains important for interaction with the c-Met receptor
-
Lokker N.A., Presta L.G., Godowski P.J. Mutational analysis and molecular modeling of the N-terminal kringle-containing domain of hepatocyte growth factor identifies amino acid side chains important for interaction with the c-Met receptor. Protein Eng. 1994, 7:895-903.
-
(1994)
Protein Eng.
, vol.7
, pp. 895-903
-
-
Lokker, N.A.1
Presta, L.G.2
Godowski, P.J.3
-
71
-
-
0028181118
-
Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor)
-
Longati P., Bardelli A., Ponzetto C., Naldini L., Comoglio P.M. Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor). Oncogene 1994, 9:49-57.
-
(1994)
Oncogene
, vol.9
, pp. 49-57
-
-
Longati, P.1
Bardelli, A.2
Ponzetto, C.3
Naldini, L.4
Comoglio, P.M.5
-
72
-
-
0141507038
-
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D
-
Love C.A., Harlos K., Mavaddat N., Davis S.J., Stuart D.I., Jones E.Y., Esnouf R.M. The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D. Nat. Struct. Biol. 2003, 10:843-848.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 843-848
-
-
Love, C.A.1
Harlos, K.2
Mavaddat, N.3
Davis, S.J.4
Stuart, D.I.5
Jones, E.Y.6
Esnouf, R.M.7
-
73
-
-
0037560892
-
Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes
-
Machner M.P., Frese S., Schubert W.D., Orian-Rousseau V., Gherardi E., Wehland J., Niemann H.H., Heinz D.W. Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes. Mol. Microbiol. 2003, 48:1525-1536.
-
(2003)
Mol. Microbiol.
, vol.48
, pp. 1525-1536
-
-
Machner, M.P.1
Frese, S.2
Schubert, W.D.3
Orian-Rousseau, V.4
Gherardi, E.5
Wehland, J.6
Niemann, H.H.7
Heinz, D.W.8
-
74
-
-
0036845352
-
GW domains of the Listeria monocytogenes invasion protein InlB are SH3-like and mediate binding to host ligands
-
Marino M., Banerjee M., Jonquieres R., Cossart P., Ghosh P. GW domains of the Listeria monocytogenes invasion protein InlB are SH3-like and mediate binding to host ligands. EMBO J. 2002, 21:5623-5634.
-
(2002)
EMBO J.
, vol.21
, pp. 5623-5634
-
-
Marino, M.1
Banerjee, M.2
Jonquieres, R.3
Cossart, P.4
Ghosh, P.5
-
75
-
-
0033256246
-
Structure of the lnlB leucine-rich repeats, a domain that triggers host cell invasion by the bacterial pathogen L. monocytogenes
-
Marino M., Braun L., Cossart P., Ghosh P. Structure of the lnlB leucine-rich repeats, a domain that triggers host cell invasion by the bacterial pathogen L. monocytogenes. Mol. Cell 1999, 4:1063-1072.
-
(1999)
Mol. Cell
, vol.4
, pp. 1063-1072
-
-
Marino, M.1
Braun, L.2
Cossart, P.3
Ghosh, P.4
-
76
-
-
77955938954
-
Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer
-
Maun H.R., Kirchhofer D., Lazarus R.A. Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer. Biol. Chem. 2010, 391:881-892.
-
(2010)
Biol. Chem.
, vol.391
, pp. 881-892
-
-
Maun, H.R.1
Kirchhofer, D.2
Lazarus, R.A.3
-
77
-
-
85047689927
-
An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice
-
Mazzone M., Basilico C., Cavassa S., Pennacchietti S., Risio M., Naldini L., Comoglio P.M., Michieli P. An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice. J. Clin. Invest. 2004, 114:1418-1432.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1418-1432
-
-
Mazzone, M.1
Basilico, C.2
Cavassa, S.3
Pennacchietti, S.4
Risio, M.5
Naldini, L.6
Comoglio, P.M.7
Michieli, P.8
-
78
-
-
33749367676
-
The Met pathway: master switch and drug target in cancer progression
-
Mazzone M., Comoglio P.M. The Met pathway: master switch and drug target in cancer progression. FASEB J. 2006, 20:1611-1621.
-
(2006)
FASEB J.
, vol.20
, pp. 1611-1621
-
-
Mazzone, M.1
Comoglio, P.M.2
-
79
-
-
67449085889
-
Deletion of the ectodomain unleashes the transforming, invasive, and tumorigenic potential of the MET oncogene
-
Merlin S., Pietronave S., Locarno D., Valente G., Follenzi A., Prat M. Deletion of the ectodomain unleashes the transforming, invasive, and tumorigenic potential of the MET oncogene. Cancer Sci. 2009, 100:633-638.
-
(2009)
Cancer Sci.
, vol.100
, pp. 633-638
-
-
Merlin, S.1
Pietronave, S.2
Locarno, D.3
Valente, G.4
Follenzi, A.5
Prat, M.6
-
80
-
-
3142512610
-
Targeting the tumor and its microenvironment by a dual-function decoy Met receptor
-
Michieli P., Mazzone M., Basilico C., Cavassa S., Sottile A., Naldini L., Comoglio P.M. Targeting the tumor and its microenvironment by a dual-function decoy Met receptor. Cancer Cell 2004, 6:61-73.
-
(2004)
Cancer Cell
, vol.6
, pp. 61-73
-
-
Michieli, P.1
Mazzone, M.2
Basilico, C.3
Cavassa, S.4
Sottile, A.5
Naldini, L.6
Comoglio, P.M.7
-
81
-
-
0024455086
-
Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor
-
Miyazawa K., Tsubouchi H., Naka D., Takahashi K., Okigaki M., Arakaki N., Nakayama H., Hirono S., Sakiyama O., Takahashi K., et al. Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor. Biochem. Biophys. Res. Commun. 1989, 163:967-973.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.163
, pp. 967-973
-
-
Miyazawa, K.1
Tsubouchi, H.2
Naka, D.3
Takahashi, K.4
Okigaki, M.5
Arakaki, N.6
Nakayama, H.7
Hirono, S.8
Sakiyama, O.9
Takahashi, K.10
-
83
-
-
0024427178
-
Molecular cloning and expression of human hepatocyte growth factor
-
Nakamura T., Nishizawa T., Hagiya M., Seki T., Shimonishi M., Sugimura A., Tashiro K., Shimizu S. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989, 342:440-443.
-
(1989)
Nature
, vol.342
, pp. 440-443
-
-
Nakamura, T.1
Nishizawa, T.2
Hagiya, M.3
Seki, T.4
Shimonishi, M.5
Sugimura, A.6
Tashiro, K.7
Shimizu, S.8
-
84
-
-
34447548559
-
Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB
-
Niemann H.H., Jager V., Butler P.J., van den Heuvel J., Schmidt S., Ferraris D., Gherardi E., Heinz D.W. Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB. Cell 2007, 130:235-246.
-
(2007)
Cell
, vol.130
, pp. 235-246
-
-
Niemann, H.H.1
Jager, V.2
Butler, P.J.3
van den Heuvel, J.4
Schmidt, S.5
Ferraris, D.6
Gherardi, E.7
Heinz, D.W.8
-
85
-
-
40249114708
-
X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB
-
Niemann H.H., Petoukhov M.V., Hartlein M., Moulin M., Gherardi E., Timmins P., Heinz D.W., Svergun D.I. X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB. J. Mol. Biol. 2008, 377:489-500.
-
(2008)
J. Mol. Biol.
, vol.377
, pp. 489-500
-
-
Niemann, H.H.1
Petoukhov, M.V.2
Hartlein, M.3
Moulin, M.4
Gherardi, E.5
Timmins, P.6
Heinz, D.W.7
Svergun, D.I.8
-
86
-
-
18644386251
-
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
-
Ogiso H., Ishitani R., Nureki O., Fukai S., Yamanaka M., Kim J.H., Saito K., Sakamoto A., Inoue M., Shirouzu M., Yokoyama S. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell 2002, 110:775-787.
-
(2002)
Cell
, vol.110
, pp. 775-787
-
-
Ogiso, H.1
Ishitani, R.2
Nureki, O.3
Fukai, S.4
Yamanaka, M.5
Kim, J.H.6
Saito, K.7
Sakamoto, A.8
Inoue, M.9
Shirouzu, M.10
Yokoyama, S.11
-
87
-
-
1242348060
-
Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors
-
Park M., Dean M., Kaul K., Braun M.J., Gonda M.A., Vande Woude G. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc. Natl. Acad. Sci. U.S.A. 1987, 84:6379-6383.
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 6379-6383
-
-
Park, M.1
Dean, M.2
Kaul, K.3
Braun, M.J.4
Gonda, M.A.5
Vande Woude, G.6
-
88
-
-
0034718796
-
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
-
Pellegrini L., Burke D.F., von Delft F., Mulloy B., Blundell T.L. Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin. Nature 2000, 407:1029-1034.
-
(2000)
Nature
, vol.407
, pp. 1029-1034
-
-
Pellegrini, L.1
Burke, D.F.2
von Delft, F.3
Mulloy, B.4
Blundell, T.L.5
-
89
-
-
33745697763
-
Targeting the c-Met signaling pathway in cancer
-
Peruzzi B., Bottaro D.P. Targeting the c-Met signaling pathway in cancer. Clin. Cancer Res. 2006, 12:3657-3660.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 3657-3660
-
-
Peruzzi, B.1
Bottaro, D.P.2
-
90
-
-
0037075606
-
The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met
-
Petrelli A., Gilestro G.F., Lanzardo S., Comoglio P.M., Migone N., Giordano S. The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. Nature 2002, 416:187-190.
-
(2002)
Nature
, vol.416
, pp. 187-190
-
-
Petrelli, A.1
Gilestro, G.F.2
Lanzardo, S.3
Comoglio, P.M.4
Migone, N.5
Giordano, S.6
-
91
-
-
0034640103
-
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity
-
Plotnikov A.N., Hubbard S.R., Schlessinger J., Mohammadi M. Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity. Cell 2000, 101:413-424.
-
(2000)
Cell
, vol.101
, pp. 413-424
-
-
Plotnikov, A.N.1
Hubbard, S.R.2
Schlessinger, J.3
Mohammadi, M.4
-
92
-
-
0033520472
-
Structural basis for FGF receptor dimerization and activation
-
Plotnikov A.N., Schlessinger J., Hubbard S.R., Mohammadi M. Structural basis for FGF receptor dimerization and activation. Cell 1999, 98:641-650.
-
(1999)
Cell
, vol.98
, pp. 641-650
-
-
Plotnikov, A.N.1
Schlessinger, J.2
Hubbard, S.R.3
Mohammadi, M.4
-
93
-
-
0028351702
-
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
-
Ponzetto C., Bardelli A., Zhen Z., Maina F., dalla Zonca P., Giordano S., Graziani A., Panayotou G., Comoglio P.M. A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 1994, 77:261-271.
-
(1994)
Cell
, vol.77
, pp. 261-271
-
-
Ponzetto, C.1
Bardelli, A.2
Zhen, Z.3
Maina, F.4
dalla Zonca, P.5
Giordano, S.6
Graziani, A.7
Panayotou, G.8
Comoglio, P.M.9
-
94
-
-
0031906957
-
Agonistic monoclonal antibodies against the Met receptor dissect the biological responses to HGF
-
Prat M., Crepaldi T., Pennacchietti S., Bussolino F., Comoglio P.M. Agonistic monoclonal antibodies against the Met receptor dissect the biological responses to HGF. J. Cell Sci. 1998, 111:237-247.
-
(1998)
J. Cell Sci.
, vol.111
, pp. 237-247
-
-
Prat, M.1
Crepaldi, T.2
Pennacchietti, S.3
Bussolino, F.4
Comoglio, P.M.5
-
95
-
-
0027369598
-
Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase
-
Rodrigues G.A., Park M. Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase. Mol. Cell. Biol. 1993, 13:6711-6722.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6711-6722
-
-
Rodrigues, G.A.1
Park, M.2
-
96
-
-
0034683667
-
Essential role of Gab1 for signaling by the c-Met receptor in vivo
-
Sachs M., Brohmann H., Zechner D., Muller T., Hulsken J., Walther I., Schaeper U., Birchmeier C., Birchmeier W. Essential role of Gab1 for signaling by the c-Met receptor in vivo. J. Cell Biol. 2000, 150:1375-1384.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1375-1384
-
-
Sachs, M.1
Brohmann, H.2
Zechner, D.3
Muller, T.4
Hulsken, J.5
Walther, I.6
Schaeper, U.7
Birchmeier, C.8
Birchmeier, W.9
-
97
-
-
30444433575
-
Structural basis for Gas6-Axl signalling
-
Sasaki T., Knyazev P.G., Clout N.J., Cheburkin Y., Gohring W., Ullrich A., Timpl R., Hohenester E. Structural basis for Gas6-Axl signalling. EMBO J. 2006, 25:80-87.
-
(2006)
EMBO J.
, vol.25
, pp. 80-87
-
-
Sasaki, T.1
Knyazev, P.G.2
Clout, N.J.3
Cheburkin, Y.4
Gohring, W.5
Ullrich, A.6
Timpl, R.7
Hohenester, E.8
-
98
-
-
0023686033
-
Signal transduction by allosteric receptor oligomerization
-
Schlessinger J. Signal transduction by allosteric receptor oligomerization. Trends Biochem. Sci. 1988, 13:443-447.
-
(1988)
Trends Biochem. Sci.
, vol.13
, pp. 443-447
-
-
Schlessinger, J.1
-
99
-
-
0037145061
-
Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
-
Schlessinger J. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 2002, 110:669-672.
-
(2002)
Cell
, vol.110
, pp. 669-672
-
-
Schlessinger, J.1
-
100
-
-
0033635299
-
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization
-
Schlessinger J., Plotnikov A.N., Ibrahimi O.A., Eliseenkova A.V., Yeh B.K., Yayon A., Linhardt R.J., Mohammadi M. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol. Cell 2000, 6:743-750.
-
(2000)
Mol. Cell
, vol.6
, pp. 743-750
-
-
Schlessinger, J.1
Plotnikov, A.N.2
Ibrahimi, O.A.3
Eliseenkova, A.V.4
Yeh, B.K.5
Yayon, A.6
Linhardt, R.J.7
Mohammadi, M.8
-
101
-
-
0035965120
-
Internalins from the human pathogen Listeria monocytogenes combine three distinct folds into a contiguous internalin domain
-
Schubert W.D., Gobel G., Diepholz M., Darji A., Kloer D., Hain T., Chakraborty T., Wehland J., Domann E., Heinz D.W. Internalins from the human pathogen Listeria monocytogenes combine three distinct folds into a contiguous internalin domain. J. Mol. Biol. 2001, 312:783-794.
-
(2001)
J. Mol. Biol.
, vol.312
, pp. 783-794
-
-
Schubert, W.D.1
Gobel, G.2
Diepholz, M.3
Darji, A.4
Kloer, D.5
Hain, T.6
Chakraborty, T.7
Wehland, J.8
Domann, E.9
Heinz, D.W.10
-
102
-
-
0347417963
-
Structural aspects of adhesion to and invasion of host cells by the human pathogen Listeria monocytogenes
-
Schubert W.D., Heinz D.W. Structural aspects of adhesion to and invasion of host cells by the human pathogen Listeria monocytogenes. Chembiochem 2003, 4:1285-1291.
-
(2003)
Chembiochem
, vol.4
, pp. 1285-1291
-
-
Schubert, W.D.1
Heinz, D.W.2
-
103
-
-
0037074015
-
Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin
-
Schubert W.D., Urbanke C., Ziehm T., Beier V., Machner M.P., Domann E., Wehland J., Chakraborty T., Heinz D.W. Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin. Cell 2002, 111:825-836.
-
(2002)
Cell
, vol.111
, pp. 825-836
-
-
Schubert, W.D.1
Urbanke, C.2
Ziehm, T.3
Beier, V.4
Machner, M.P.5
Domann, E.6
Wehland, J.7
Chakraborty, T.8
Heinz, D.W.9
-
104
-
-
0029897025
-
Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2
-
Schwall R.H., Chang L.Y., Godowski P.J., Kahn D.W., Hillan K.J., Bauer K.D., Zioncheck T.F. Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2. J. Cell Biol. 1996, 133:709-718.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 709-718
-
-
Schwall, R.H.1
Chang, L.Y.2
Godowski, P.J.3
Kahn, D.W.4
Hillan, K.J.5
Bauer, K.D.6
Zioncheck, T.F.7
-
105
-
-
8144221077
-
Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
-
Scott P.G., McEwan P.A., Dodd C.M., Bergmann E.M., Bishop P.N., Bella J. Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:15633-15638.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 15633-15638
-
-
Scott, P.G.1
McEwan, P.A.2
Dodd, C.M.3
Bergmann, E.M.4
Bishop, P.N.5
Bella, J.6
-
106
-
-
77950516909
-
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly
-
Seiradake E., Harlos K., Sutton G., Aricescu A.R., Jones E.Y. An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Nat. Struct. Mol. Biol. 2010, 17:398-402.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 398-402
-
-
Seiradake, E.1
Harlos, K.2
Sutton, G.3
Aricescu, A.R.4
Jones, E.Y.5
-
107
-
-
0034721647
-
InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase
-
Shen Y., Naujokas M., Park M., Ireton K. InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase. Cell 2000, 103:501-510.
-
(2000)
Cell
, vol.103
, pp. 501-510
-
-
Shen, Y.1
Naujokas, M.2
Park, M.3
Ireton, K.4
-
108
-
-
3142595278
-
Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor
-
Stamos J., Lazarus R.A., Yao X., Kirchhofer D., Wiesmann C. Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor. EMBO J. 2004, 23:2325-2335.
-
(2004)
EMBO J.
, vol.23
, pp. 2325-2335
-
-
Stamos, J.1
Lazarus, R.A.2
Yao, X.3
Kirchhofer, D.4
Wiesmann, C.5
-
110
-
-
0023661693
-
Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
-
Stoker M., Gherardi E., Perryman M., Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 1987, 327:239-242.
-
(1987)
Nature
, vol.327
, pp. 239-242
-
-
Stoker, M.1
Gherardi, E.2
Perryman, M.3
Gray, J.4
-
111
-
-
0023790119
-
Structure of the met protein and variation of met protein kinase activity among human tumour cell lines
-
Tempest P.R., Stratton M.R., Cooper C.S. Structure of the met protein and variation of met protein kinase activity among human tumour cell lines. Br. J. Cancer 1988, 58:3-7.
-
(1988)
Br. J. Cancer
, vol.58
, pp. 3-7
-
-
Tempest, P.R.1
Stratton, M.R.2
Cooper, C.S.3
-
112
-
-
77955810458
-
Structural basis for agonism and antagonism of hepatocyte growth factor
-
Tolbert W.D., Daugherty-Holtrop J., Gherardi E., Vande Woude G., Xu H.E. Structural basis for agonism and antagonism of hepatocyte growth factor. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:13264-13269.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 13264-13269
-
-
Tolbert, W.D.1
Daugherty-Holtrop, J.2
Gherardi, E.3
Vande Woude, G.4
Xu, H.E.5
-
113
-
-
35548953605
-
A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist
-
Tolbert W.D., Daugherty J., Gao C., Xie Q., Miranti C., Gherardi E., Woude G.V., Xu H.E. A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:14592-14597.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 14592-14597
-
-
Tolbert, W.D.1
Daugherty, J.2
Gao, C.3
Xie, Q.4
Miranti, C.5
Gherardi, E.6
Woude, G.V.7
Xu, H.E.8
-
114
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich A., Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell 1990, 61:203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
115
-
-
0032533765
-
Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 A resolution
-
Ultsch M., Lokker N.A., Godowski P.J., de Vos A.M. Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 A resolution. Structure 1998, 6:1383-1393.
-
(1998)
Structure
, vol.6
, pp. 1383-1393
-
-
Ultsch, M.1
Lokker, N.A.2
Godowski, P.J.3
de Vos, A.M.4
-
116
-
-
26244460357
-
Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival
-
Urbanek K., Rota M., Cascapera S., Bearzi C., Nascimbene A., De Angelis A., Hosoda T., Chimenti S., Baker M., Limana F., Nurzynska D., Torella D., Rotatori F., Rastaldo R., Musso E., Quaini F., Leri A., Kajstura J., Anversa P. Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival. Circ. Res. 2005, 97:663-673.
-
(2005)
Circ. Res.
, vol.97
, pp. 663-673
-
-
Urbanek, K.1
Rota, M.2
Cascapera, S.3
Bearzi, C.4
Nascimbene, A.5
De Angelis, A.6
Hosoda, T.7
Chimenti, S.8
Baker, M.9
Limana, F.10
Nurzynska, D.11
Torella, D.12
Rotatori, F.13
Rastaldo, R.14
Musso, E.15
Quaini, F.16
Leri, A.17
Kajstura, J.18
Anversa, P.19
-
117
-
-
26944438047
-
Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells
-
Veiga E., Cossart P. Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells. Nat. Cell Biol. 2005, 7:894-900.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 894-900
-
-
Veiga, E.1
Cossart, P.2
-
118
-
-
35848959730
-
Invasive and adherent bacterial pathogens co-Opt host clathrin for infection
-
Veiga E., Guttman J.A., Bonazzi M., Boucrot E., Toledo-Arana A., Lin A.E., Enninga J., Pizarro-Cerda J., Finlay B.B., Kirchhausen T., Cossart P. Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host Microbe 2007, 2:340-351.
-
(2007)
Cell Host Microbe
, vol.2
, pp. 340-351
-
-
Veiga, E.1
Guttman, J.A.2
Bonazzi, M.3
Boucrot, E.4
Toledo-Arana, A.5
Lin, A.E.6
Enninga, J.7
Pizarro-Cerda, J.8
Finlay, B.B.9
Kirchhausen, T.10
Cossart, P.11
-
119
-
-
0036304963
-
A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping
-
Watanabe K., Chirgadze D.Y., Lietha D., de Jonge H., Blundell T.L., Gherardi E. A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping. J. Mol. Biol. 2002, 319:283-288.
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 283-288
-
-
Watanabe, K.1
Chirgadze, D.Y.2
Lietha, D.3
de Jonge, H.4
Blundell, T.L.5
Gherardi, E.6
-
120
-
-
0030782410
-
Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor
-
Wiesmann C., Fuh G., Christinger H.W., Eigenbrot C., Wells J.A., de Vos A.M. Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Cell 1997, 91:695-704.
-
(1997)
Cell
, vol.91
, pp. 695-704
-
-
Wiesmann, C.1
Fuh, G.2
Christinger, H.W.3
Eigenbrot, C.4
Wells, J.A.5
de Vos, A.M.6
-
121
-
-
40849135544
-
Engineering the NK1 fragment of hepatocyte growth factor/scatter factor as a MET receptor antagonist
-
Youles M., Holmes O., Petoukhov M.V., Nessen M.A., Stivala S., Svergun D.I., Gherardi E. Engineering the NK1 fragment of hepatocyte growth factor/scatter factor as a MET receptor antagonist. J. Mol. Biol. 2008, 377:616-622.
-
(2008)
J. Mol. Biol.
, vol.377
, pp. 616-622
-
-
Youles, M.1
Holmes, O.2
Petoukhov, M.V.3
Nessen, M.A.4
Stivala, S.5
Svergun, D.I.6
Gherardi, E.7
-
122
-
-
34447531743
-
Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor
-
Yuzawa S., Opatowsky Y., Zhang Z., Mandiyan V., Lax I., Schlessinger J. Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. Cell 2007, 130:323-334.
-
(2007)
Cell
, vol.130
, pp. 323-334
-
-
Yuzawa, S.1
Opatowsky, Y.2
Zhang, Z.3
Mandiyan, V.4
Lax, I.5
Schlessinger, J.6
-
123
-
-
0029034348
-
Sulfated oligosaccharides promote hepatocyte growth factor association and govern its mitogenic activity
-
Zioncheck T.F., Richardson L., Liu J., Chang L., King K.L., Bennett G.L., Fugedi P., Chamow S.M., Schwall R.H., Stack R.J. Sulfated oligosaccharides promote hepatocyte growth factor association and govern its mitogenic activity. J. Biol. Chem. 1995, 270:16871-16878.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16871-16878
-
-
Zioncheck, T.F.1
Richardson, L.2
Liu, J.3
Chang, L.4
King, K.L.5
Bennett, G.L.6
Fugedi, P.7
Chamow, S.M.8
Schwall, R.H.9
Stack, R.J.10
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