-
1
-
-
0033215478
-
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
-
DOI 10.1006/jmbi.1999.3108
-
Moore, R. C., I. Y. Lee, G. L. Silverman, P. M. Harrison, R. Strome, C. Heinrich, A. Karunaratne, S. H. Pasternak, M. A. Chishti, Y. Liang, P. Mastrangelo, K. Wang, A. F. Smit, S. Katamine, G. A. Carlson, F. E. Cohen, S. B. Prusiner, D. W. Melton, P. Tremblay, L. E. Hood & D. Westaway: Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J Mol Biol, 292, 797-817 (1999) (Pubitemid 29465475)
-
(1999)
Journal of Molecular Biology
, vol.292
, Issue.4
, pp. 797-817
-
-
Moore, R.C.1
Lee, I.Y.2
Silverman, G.L.3
Harrison, P.M.4
Strome, R.5
Heinrich, C.6
Karunaratne, A.7
Pasternak, S.H.8
Chishti, M.A.9
Liang, Y.10
Mastrangelo, P.11
Wang, K.12
Smit, A.F.A.13
Katamine, S.14
Carlson, G.A.15
Cohen, F.E.16
Prusiner, S.B.17
Melton, D.W.18
Tremblay, P.19
Hood, L.E.20
Westaway, D.21
more..
-
2
-
-
8444247483
-
Evolution of vertebrate genes related to prion and shadoo proteins - Clues from comparative genomic analysis
-
DOI 10.1093/molbev/msh245
-
Premzl, M., J. E. Gready, L. S. Jermiin, T. Simonic & J. A. Marshall Graves: Evolution of vertebrate genes related to prion and Shadoo proteins-clues from comparative genomic analysis. Mol Biol Evol, 21, 2210-31 (2004) (Pubitemid 39488893)
-
(2004)
Molecular Biology and Evolution
, vol.21
, Issue.12
, pp. 2210-2231
-
-
Premzl, M.1
Gready, J.E.2
Jermiin, L.S.3
Simonic, T.4
Marshall Graves, J.A.5
-
3
-
-
0141760321
-
Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein
-
DOI 10.1016/S0378-1119(03)00707-8
-
Premzl, M., L. Sangiorgio, B. Strumbo, J. A. Marshall Graves, T. Simonic & J. E. Gready: Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein. Gene, 314, 89-102 (2003) (Pubitemid 37186922)
-
(2003)
Gene
, vol.314
, Issue.1-2
, pp. 89-102
-
-
Premzl, M.1
Sangiorgio, L.2
Strumbo, B.3
Marshall Graves, J.A.4
Simonic, T.5
Gready, J.E.6
-
4
-
-
34548384916
-
C-like protective properties and displays reduced levels in prion infections
-
DOI 10.1038/sj.emboj.7601830, PII 7601830
-
Watts, J. C., B. Drisaldi, V. Ng, J. Yang, B. Strome, P. Horne, M. S. Sy, L. Yoong, R. Young, P. Mastrangelo, C. Bergeron, P. E. Fraser, G. A. Carlson, H. T. Mount, G. Schmitt-Ulms & D. Westaway: The CNS glycoprotein Shadoo has PrP (C)-like protective properties and displays reduced levels in prion infections. Embo J, 26, 4038-50 (2007) (Pubitemid 47367498)
-
(2007)
EMBO Journal
, vol.26
, Issue.17
, pp. 4038-4050
-
-
Watts, J.C.1
Drisaldi, B.2
Ng, V.3
Yang, J.4
Strome, B.5
Horne, P.6
Sy, M.-S.7
Yoong, L.8
Young, R.9
Mastrangelo, P.10
Bergeron, C.11
Fraser, P.E.12
Carlson, G.A.13
Mount, H.T.J.14
Schmitt-Ulms, G.15
Westaway, D.16
-
5
-
-
33846844874
-
Comparative genomic analysis of prion genes
-
Premzl, M. & V. Gamulin: Comparative genomic analysis of prion genes. BMC Genomics, 8, 1 (2007)
-
(2007)
BMC Genomics
, vol.8
, pp. 1
-
-
Premzl, M.1
Gamulin, V.2
-
6
-
-
57849159034
-
Differential expression of Prnp and Sprn in scrapie infected sheep also reveals Prnp genotype specific differences
-
Gossner, A. G., N. Bennet, N. Hunter & J. Hopkins: Differential expression of Prnp and Sprn in scrapie infected sheep also reveals Prnp genotype specific differences. Biochem Biophys Res Commun, 378, 862-6 (2009)
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 862-866
-
-
Gossner, A.G.1
Bennet, N.2
Hunter, N.3
Hopkins, J.4
-
7
-
-
59049096630
-
Positive correlation between relative mRNA expression of PRNP and SPRN in cerebral and cerebellar cortex of sheep
-
Lampo, E., M. Van Poucke, J. Vandesompele, T. Erkens, A. Van Zeveren & L. J. Peelman: Positive correlation between relative mRNA expression of PRNP and SPRN in cerebral and cerebellar cortex of sheep. Mol Cell Probes, 23, 60-4 (2009)
-
(2009)
Mol Cell Probes
, vol.23
, pp. 60-64
-
-
Lampo, E.1
Van Poucke, M.2
Vandesompele, J.3
Erkens, T.4
Van Zeveren, A.5
Peelman, L.J.6
-
8
-
-
77951635216
-
Identification of polymorphisms in the ovine Shadow of prion protein (SPRN) gene and assessment of their effect on promoter activity and susceptibility for classical scrapie
-
Lampo, E., L. Duchateau, B. Schepens, M. Van Poucke, X. Saelens, T. Erkens, A. Van Zeveren & L. J. Peelman: Identification of polymorphisms in the ovine Shadow of prion protein (SPRN) gene and assessment of their effect on promoter activity and susceptibility for classical scrapie. Anim Genet, 41, 169-78 (2010)
-
(2010)
Anim Genet
, vol.41
, pp. 169-178
-
-
Lampo, E.1
Duchateau, L.2
Schepens, B.3
Van Poucke, M.4
Saelens, X.5
Erkens, T.6
Van Zeveren, A.7
Peelman, L.J.8
-
9
-
-
33751075179
-
Cloning of the bovine prion-like Shadoo (SPRN) gene by comparative analysis of the predicted genomic locus
-
DOI 10.1007/s00335-006-0078-7
-
Uboldi, C., M. Paulis, E. Guidi, A. Bertoni, G. P. Meo, A. Perucatti, L. Iannuzzi, E. Raimondi, R. M. Brunner, A. Eggen & L. Ferretti: Cloning of the bovine prion-like Shadoo (SPRN) gene by comparative analysis of the predicted genomic locus. Mamm Genome, 17, 1130-9 (2006) (Pubitemid 44764291)
-
(2006)
Mammalian Genome
, vol.17
, Issue.11
, pp. 1130-1139
-
-
Uboldi, C.1
Paulis, M.2
Guidi, E.3
Bertoni, A.4
Meo, G.P.D.5
Perucatti, A.6
Iannuzzi, L.7
Raimondi, E.8
Brunner, R.M.9
Eggen, A.10
Ferretti, L.11
-
10
-
-
30944451121
-
Prion protein-related proteins from zebrafish are complex glycosylated and contain a glycosylphosphatidylinositol anchor
-
DOI 10.1016/j.bbrc.2005.12.168, PII S0006291X05029384
-
Miesbauer, M., T. Bamme, C. Riemer, B. Oidtmann, K. F. Winklhofer, M. Baier & J. Tatzelt: Prion protein-related proteins from zebrafish are complex glycosylated and contain a glycosylphosphatidylinositol anchor. Biochem Biophys Res Commun, 341, 218-24 (2006) (Pubitemid 43117407)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.341
, Issue.1
, pp. 218-224
-
-
Miesbauer, M.1
Bamme, T.2
Riemer, C.3
Oidtmann, B.4
Winklhofer, K.F.5
Baier, M.6
Tatzelt, J.7
-
11
-
-
0028339962
-
Proposed three-dimensional structure for the cellular prion protein
-
DOI 10.1073/pnas.91.15.7139
-
Huang, Z., J. M. Gabriel, M. A. Baldwin, R. J. Fletterick, S. B. Prusiner & F. E. Cohen: Proposed threedimensional structure for the cellular prion protein. Proc Natl Acad Sci U S A, 91, 7139-43 (1994) (Pubitemid 24226818)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.15
, pp. 7139-7143
-
-
Huang, Z.1
Gabriel, J.-M.2
Baldwin, M.A.3
Fletterick, R.J.4
Prusiner, S.B.5
Cohen, F.E.6
-
12
-
-
77749264931
-
Wild-type Shadoo proteins convert to amyloid-like forms under native conditions
-
Daude, N., V. Ng, J. C. Watts, S. Genovesi, J. P. Glaves, S. Wohlgemuth, G. Schmitt-Ulms, H. Young, J. McLaurin, P. E. Fraser & D. Westaway: Wild-type Shadoo proteins convert to amyloid-like forms under native conditions. J Neurochem, 113, 92-104 (2010)
-
(2010)
J Neurochem
, vol.113
, pp. 92-104
-
-
Daude, N.1
Ng, V.2
Watts, J.C.3
Genovesi, S.4
Glaves, J.P.5
Wohlgemuth, S.6
Schmitt-Ulms, G.7
Young, H.8
McLaurin, J.9
Fraser, P.E.10
Westaway, D.11
-
13
-
-
0032488777
-
A transmembrane form of the prion protein in neurodegenerative disease
-
DOI 10.1126/science.279.5352.827
-
Hegde, R. S., J. A. Mastrianni, M. R. Scott, K. A. DeFea, P. Tremblay, M. Torchia, S. J. DeArmond, S. B. Prusiner & V. R. Lingappa: A transmembrane form of the prion protein in neurodegenerative disease. Science, 279, 827-34 (1998) (Pubitemid 28106269)
-
(1998)
Science
, vol.279
, Issue.5352
, pp. 827-834
-
-
Hegde, R.S.1
Mastrianni, J.A.2
Scott, M.R.3
DeFea, K.A.4
Tremblay, P.5
Torchia, M.6
DeArmond, S.J.7
Prusiner, S.B.8
Lingappa, V.R.9
-
14
-
-
77149179440
-
Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein
-
Rane, N. S., O. Chakrabarti, L. Feigenbaum & R. S. Hegde: Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein. J Cell Biol, 188, 515-26 (2010)
-
(2010)
J Cell Biol
, vol.188
, pp. 515-526
-
-
Rane, N.S.1
Chakrabarti, O.2
Feigenbaum, L.3
Hegde, R.S.4
-
15
-
-
0028402693
-
A dimerization motif for transmembrane alpha-helices
-
Lemmon, M. A., H. R. Treutlein, P. D. Adams, A. T. Brunger & D. M. Engelman: A dimerization motif for transmembrane alpha-helices. Nat Struct Biol, 1, 157-63 (1994)
-
(1994)
Nat Struct Biol
, vol.1
, pp. 157-163
-
-
Lemmon, M.A.1
Treutlein, H.R.2
Adams, P.D.3
Brunger, A.T.4
Engelman, D.M.5
-
16
-
-
0034711953
-
The GxxxG motif: A framework for transmembrane helix-helix association
-
Russ, W. P. & D. M. Engelman: The GxxxG motif: a framework for transmembrane helix-helix association. J Mol Biol, 296, 911-9 (2000)
-
(2000)
J Mol Biol
, vol.296
, pp. 911-919
-
-
Russ, W.P.1
Engelman, D.M.2
-
17
-
-
0034711958
-
Statistical analysis of amino acid patterns in transmembrane helices: The GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions
-
Senes, A., M. Gerstein & D. M. Engelman: Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions. J Mol Biol, 296, 921-36 (2000)
-
(2000)
J Mol Biol
, vol.296
, pp. 921-936
-
-
Senes, A.1
Gerstein, M.2
Engelman, D.M.3
-
18
-
-
14644390240
-
Structural role of glycine in amyloid fibrils formed from transmembrane α-helices
-
DOI 10.1021/bi047827g
-
Liu, W., E. Crocker, W. Zhang, J. I. Elliott, B. Luy, H. Li, S. Aimoto & S. O. Smith: Structural role of glycine in amyloid fibrils formed from transmembrane alpha-helices. Biochemistry, 44, 3591-7 (2005) (Pubitemid 40322028)
-
(2005)
Biochemistry
, vol.44
, Issue.9
, pp. 3591-3597
-
-
Liu, W.1
Crocker, E.2
Zhang, W.3
Elliott, J.I.4
Luy, B.5
Li, H.6
Aimoto, S.7
Smith, S.O.8
-
19
-
-
33749001207
-
A trimerizing GxxxG Motif is uniquely inserted in the severe acute respiratory syndrome (SARS) coronavirus spike protein transmembrane domain
-
DOI 10.1021/bi060953v
-
Arbely, E., Z. Granot, I. Kass, J. Orly & I. T. Arkin: A trimerizing GxxxG motif is uniquely inserted in the severe acute respiratory syndrome (SARS) coronavirus spike protein transmembrane domain. Biochemistry, 45, 11349-56 (2006) (Pubitemid 44453983)
-
(2006)
Biochemistry
, vol.45
, Issue.38
, pp. 11349-11356
-
-
Arbely, E.1
Granot, Z.2
Kass, I.3
Orly, J.4
Arkin, I.T.5
-
20
-
-
77956210935
-
Characterization of the GXXXG motif in the first transmembrane segment of Japanese encephalitis virus precursor membrane (prM) protein
-
Lin, Y. J., J. G. Peng & S. C. Wu: Characterization of the GXXXG motif in the first transmembrane segment of Japanese encephalitis virus precursor membrane (prM) protein. J Biomed Sci, 17, 39 (2010)
-
(2010)
J Biomed Sci
, vol.17
, pp. 39
-
-
Lin, Y.J.1
Peng, J.G.2
Wu, S.C.3
-
21
-
-
33646371260
-
Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42
-
DOI 10.1021/bi052485f
-
Sato, T., P. Kienlen-Campard, M. Ahmed, W. Liu, H. Li, J. I. Elliott, S. Aimoto, S. N. Constantinescu, J. N. Octave & S. O. Smith: Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42. Biochemistry, 45, 5503-16 (2006) (Pubitemid 43673181)
-
(2006)
Biochemistry
, vol.45
, Issue.17
, pp. 5503-5516
-
-
Sato, T.1
Kienlen-Campard, P.2
Ahmed, M.3
Liu, W.4
Li, H.5
Elliott, J.I.6
Aimoto, S.7
Constantinescu, S.N.8
Octave, J.-N.9
Smith, S.O.10
-
22
-
-
33947597857
-
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42
-
DOI 10.1038/sj.emboj.7601616, PII 7601616
-
Munter, L. M., P. Voigt, A. Harmeier, D. Kaden, K. E. Gottschalk, C. Weise, R. Pipkorn, M. Schaefer, D. Langosch & G. Multhaup: GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. Embo J, 26, 1702-12 (2007) (Pubitemid 46480941)
-
(2007)
EMBO Journal
, vol.26
, Issue.6
, pp. 1702-1712
-
-
Munter, L.-M.1
Voigt, P.2
Harmeier, A.3
Kaden, D.4
Gottschalk, K.E.5
Weise, C.6
Pipkorn, R.7
Schaefer, M.8
Langosch, D.9
Multhaup, G.10
-
23
-
-
77953775185
-
Conservation of a glycine-rich region in the prion protein is required for uptake of prion infectivity
-
Harrison, C. F., V. A. Lawson, B. M. Coleman, Y. S. Kim, C. L. Masters, R. Cappai, K. J. Barnham & A. F. Hill: Conservation of a glycine-rich region in the prion protein is required for uptake of prion infectivity. J Biol Chem, 285, 20213-23 (2010)
-
(2010)
J Biol Chem
, vol.285
, pp. 20213-20223
-
-
Harrison, C.F.1
Lawson, V.A.2
Coleman, B.M.3
Kim, Y.S.4
Masters, C.L.5
Cappai, R.6
Barnham, K.J.7
Hill, A.F.8
-
24
-
-
78651250086
-
Identification of the RGG box motif in Shadoo: RNA-binding and signaling roles?
-
Corley, S. M. & J. E. Gready: Identification of the RGG box motif in Shadoo: RNA-binding and signaling roles? Bioinform Biol Insights, 2, 383-400 (2008)
-
(2008)
Bioinform Biol Insights
, vol.2
, pp. 383-400
-
-
Corley, S.M.1
Gready, J.E.2
-
25
-
-
0037409731
-
Prion protein interactions with nucleic acid: Possible models for prion disease and prion function
-
DOI 10.1023/A:1023215207981
-
Grossman, A., B. Zeiler & V. Sapirstein: Prion protein interactions with nucleic acid: Possible models for prion disease and prion function. Neurochemical Research, 28, 955-963 (2003) (Pubitemid 36438414)
-
(2003)
Neurochemical Research
, vol.28
, Issue.6
, pp. 955-963
-
-
Grossman, A.1
Zeiler, B.2
Sapirstein, V.3
-
26
-
-
77951237351
-
PrP interactions with nucleic acids and glycosaminoglycans in function and disease
-
Silva, J. L., M. P. Gomes, T. C. Vieira & Y. Cordeiro: PrP interactions with nucleic acids and glycosaminoglycans in function and disease. Front Biosci, 15, 132-50 (2010)
-
(2010)
Front Biosci
, vol.15
, pp. 132-150
-
-
Silva, J.L.1
Gomes, M.P.2
Vieira, T.C.3
Cordeiro, Y.4
-
27
-
-
61449198575
-
HECTD2 is associated with susceptibility to mouse and human prion disease
-
Lloyd, S. E., E. G. Maytham, H. Pota, J. Grizenkova, E. Molou, J. Uphill, H. Hummerich, J. Whitfield, M. P. Alpers, S. Mead & J. Collinge: HECTD2 is associated with susceptibility to mouse and human prion disease. PLoS Genet, 5, e1000383 (2009)
-
(2009)
PLoS Genet
, vol.5
-
-
Lloyd, S.E.1
Maytham, E.G.2
Pota, H.3
Grizenkova, J.4
Molou, E.5
Uphill, J.6
Hummerich, H.7
Whitfield, J.8
Alpers, M.P.9
Mead, S.10
Collinge, J.11
-
28
-
-
0037343746
-
Identification of cryptic nuclear localization signals in the prion protein
-
DOI 10.1016/S0969-9961(02)00014-1
-
Gu, Y., J. Hinnerwisch, R. Fredricks, S. Kalepu, R. S. Mishra & N. Singh: Identification of cryptic nuclear localization signals in the prion protein. Neurobiol Dis, 12, 133-49 (2003) (Pubitemid 36349405)
-
(2003)
Neurobiology of Disease
, vol.12
, Issue.2
, pp. 133-149
-
-
Gu, Y.1
Hinnerwisch, J.2
Fredricks, R.3
Kalepu, S.4
Mishra, R.S.5
Singh, N.6
-
29
-
-
0028957320
-
In vivo and in vitro arginine methylation of RNA-binding proteins
-
Liu, Q. & G. Dreyfuss: In vivo and in vitro arginine methylation of RNA-binding proteins. Mol Cell Biol, 15, 2800-8 (1995)
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2800-2808
-
-
Liu, Q.1
Dreyfuss, G.2
-
30
-
-
33645607060
-
Protein interfaces in signaling regulated by arginine methylation
-
re2
-
Boisvert, F. M., C. A. Chenard & S. Richard: Protein interfaces in signaling regulated by arginine methylation. Sci STKE, 2005, re2 (2005)
-
(2005)
Sci STKE
, vol.2005
-
-
Boisvert, F.M.1
Chenard, C.A.2
Richard, S.3
-
31
-
-
33744516148
-
Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP
-
DOI 10.1242/jcs.02882
-
Dolzhanskaya, N., G. Merz, J. M. Aletta & R. B. Denman: Methylation regulates the intracellular proteinprotein and protein-RNA interactions of FMRP. J Cell Sci, 119, 1933-46 (2006) (Pubitemid 43811018)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.9
, pp. 1933-1946
-
-
Dolzhanskaya, N.1
Merz, G.2
Aletta, J.M.3
Denman, R.B.4
-
32
-
-
67649968054
-
The protein arginine methyltransferase family: An update about function, new perspectives and the physiological role in humans
-
Wolf, S. S.: The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans. Cell Mol Life Sci, 66, 2109-21 (2009)
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2109-2121
-
-
Wolf, S.S.1
-
33
-
-
63049099537
-
Prion protein library of recombinant constructs for structural biology
-
Hornemann, S., B. Christen, C. von Schroetter, D. R. Perez & K. Wuthrich: Prion protein library of recombinant constructs for structural biology. Febs J, 276, 2359-67 (2009)
-
(2009)
Febs J
, vol.276
, pp. 2359-2367
-
-
Hornemann, S.1
Christen, B.2
Von Schroetter, C.3
Perez, D.R.4
Wuthrich, K.5
-
34
-
-
13844255387
-
Natively unfolded proteins
-
DOI 10.1016/j.sbi.2005.01.002
-
Fink, A. L.: Natively unfolded proteins. Curr Opin Struct Biol, 15, 35-41 (2005) (Pubitemid 40249507)
-
(2005)
Current Opinion in Structural Biology
, vol.15
, Issue.1 SPEC. ISS.
, pp. 35-41
-
-
Fink, A.L.1
-
35
-
-
70349470945
-
The prion or the related Shadoo protein is required for early mouse embryogenesis
-
Young, R., B. Passet, M. Vilotte, E. P. Cribiu, V. Beringue, F. Le Provost, H. Laude & J. L. Vilotte: The prion or the related Shadoo protein is required for early mouse embryogenesis. FEBS Lett, 583, 3296-300 (2009)
-
(2009)
FEBS Lett
, vol.583
, pp. 3296-3300
-
-
Young, R.1
Passet, B.2
Vilotte, M.3
Cribiu, E.P.4
Beringue, V.5
Le Provost, F.6
Laude, H.7
Vilotte, J.L.8
-
36
-
-
77649091387
-
Axonal prion protein is required for peripheral myelin maintenance
-
Bremer, J., F. Baumann, C. Tiberi, C. Wessig, H. Fischer, P. Schwarz, A. D. Steele, K. V. Toyka, K. A. Nave, J. Weis & A. Aguzzi: Axonal prion protein is required for peripheral myelin maintenance. Nat Neurosci, 13, 310-8 (2010)
-
(2010)
Nat Neurosci
, vol.13
, pp. 310-318
-
-
Bremer, J.1
Baumann, F.2
Tiberi, C.3
Wessig, C.4
Fischer, H.5
Schwarz, P.6
Steele, A.D.7
Toyka, K.V.8
Nave, K.A.9
Weis, J.10
Aguzzi, A.11
-
37
-
-
0034634655
-
Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons
-
Vincent, B., E. Paitel, Y. Frobert, S. Lehmann, J. Grassi & F. Checler: Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons. J Biol Chem, 275, 35612-6 (2000)
-
(2000)
J Biol Chem
, vol.275
, pp. 35612-35616
-
-
Vincent, B.1
Paitel, E.2
Frobert, Y.3
Lehmann, S.4
Grassi, J.5
Checler, F.6
-
38
-
-
0035851151
-
The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein
-
Vincent, B., E. Paitel, P. Saftig, Y. Frobert, D. Hartmann, B. De Strooper, J. Grassi, E. Lopez-Perez & F. Checler: The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein. J Biol Chem, 276, 37743-6 (2001)
-
(2001)
J Biol Chem
, vol.276
, pp. 37743-37746
-
-
Vincent, B.1
Paitel, E.2
Saftig, P.3
Frobert, Y.4
Hartmann, D.5
De Strooper, B.6
Grassi, J.7
Lopez-Perez, E.8
Checler, F.9
-
39
-
-
70349783752
-
Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo
-
Endres, K., G. Mitteregger, E. Kojro, H. Kretzschmar & F. Fahrenholz: Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo. Neurobiol Dis, 36, 233-41 (2009)
-
(2009)
Neurobiol Dis
, vol.36
, pp. 233-241
-
-
Endres, K.1
Mitteregger, G.2
Kojro, E.3
Kretzschmar, H.4
Fahrenholz, F.5
-
40
-
-
0027291065
-
Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor
-
Borchelt, D. R., M. Rogers, N. Stahl, G. Telling & S. B. Prusiner: Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor. Glycobiology, 3, 319-29 (1993) (Pubitemid 23281280)
-
(1993)
Glycobiology
, vol.3
, Issue.4
, pp. 319-329
-
-
Borchelt, D.R.1
Rogers, M.2
Stahl, N.3
Telling, G.4
Prusiner, S.B.5
-
41
-
-
0025091084
-
Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein
-
Stahl, N., M. A. Baldwin, A. L. Burlingame & S. B. Prusiner: Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein. Biochemistry, 29, 8879-84 (1990) (Pubitemid 20311960)
-
(1990)
Biochemistry
, vol.29
, Issue.38
, pp. 8879-8884
-
-
Stahl, N.1
Baldwin, M.A.2
Burlingame, A.L.3
Prusiner, S.B.4
-
42
-
-
69249128689
-
Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein
-
Taylor, D. R., E. T. Parkin, S. L. Cocklin, J. R. Ault, A. E. Ashcroft, A. J. Turner & N. M. Hooper: Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein. J Biol Chem, 284, 22590-600 (2009)
-
(2009)
J Biol Chem
, vol.284
, pp. 22590-22600
-
-
Taylor, D.R.1
Parkin, E.T.2
Cocklin, S.L.3
Ault, J.R.4
Ashcroft, A.E.5
Turner, A.J.6
Hooper, N.M.7
-
43
-
-
3242661985
-
GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice
-
DOI 10.1016/j.nbd.2004.05.005, PII S096999610400110X
-
Barmada, S., P. Piccardo, K. Yamaguchi, B. Ghetti & D. A. Harris: GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice. Neurobiol Dis, 16, 527-37 (2004) (Pubitemid 38942985)
-
(2004)
Neurobiology of Disease
, vol.16
, Issue.3
, pp. 527-537
-
-
Barmada, S.1
Piccardo, P.2
Yamaguchi, K.3
Ghetti, B.4
Harris, D.A.5
-
44
-
-
67749108487
-
Alternative translation initiation generates cytoplasmic sheep prion protein
-
Lund, C., C. M. Olsen, S. Skogtvedt, H. Tveit, K. Prydz & M. A. Tranulis: Alternative translation initiation generates cytoplasmic sheep prion protein. J Biol Chem, 284, 19668-78 (2009)
-
(2009)
J Biol Chem
, vol.284
, pp. 19668-19678
-
-
Lund, C.1
Olsen, C.M.2
Skogtvedt, S.3
Tveit, H.4
Prydz, K.5
Tranulis, M.A.6
-
45
-
-
0037195647
-
Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol
-
DOI 10.1126/science.1073725
-
Ma, J., R. Wollmann & S. Lindquist: Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol. Science, 298, 1781-5 (2002) (Pubitemid 35404120)
-
(2002)
Science
, vol.298
, Issue.5599
, pp. 1781-1785
-
-
Ma, J.1
Wollmann, R.2
Lindquist, S.3
-
46
-
-
0042855745
-
Cytosolic prion protein in neurons
-
Mironov, A., Jr., D. Latawiec, H. Wille, E. Bouzamondo-Bernstein, G. Legname, R. A. Williamson, D. Burton, S. J. DeArmond, S. B. Prusiner & P. J. Peters: Cytosolic prion protein in neurons. J Neurosci, 23, 7183-93 (2003) (Pubitemid 36975883)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.18
, pp. 7183-7193
-
-
Mironov Jr., A.1
Latawiec, D.2
Wille, H.3
Bouzamondo-Bernstein, E.4
Legname, G.5
Williamson, R.A.6
Burton, D.7
DeArmond, S.J.8
Prusiner, S.B.9
Peters, P.J.10
-
47
-
-
33744961080
-
The interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity
-
DOI 10.1074/jbc.M512306200
-
Wang, X., F. Wang, L. Arterburn, R. Wollmann & J. Ma: The interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity. J Biol Chem, 281, 13559-65 (2006) (Pubitemid 43855269)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.19
, pp. 13559-13565
-
-
Wang, X.1
Wang, F.2
Arterburn, L.3
Wollmann, R.4
Ma, J.5
-
48
-
-
13244295520
-
The highways and byways of prion protein trafficking
-
DOI 10.1016/j.tcb.2004.12.002, PII S0962892404003344
-
Campana, V., D. Sarnataro & C. Zurzolo: The highways and byways of prion protein trafficking. Trends Cell Biol, 15, 102-11 (2005) (Pubitemid 40188220)
-
(2005)
Trends in Cell Biology
, vol.15
, Issue.2
, pp. 102-111
-
-
Campana, V.1
Sarnataro, D.2
Zurzolo, C.3
-
49
-
-
69149103258
-
Prion protein and RNA: A view from the cytoplasm
-
Roucou, X.: Prion protein and RNA: a view from the cytoplasm. Front Biosci, 14, 5157-64 (2009)
-
(2009)
Front Biosci
, vol.14
, pp. 5157-5164
-
-
Roucou, X.1
-
50
-
-
58149375262
-
Cryo-Immunogold Electron Microscopy for Prions: Toward Identification of a Conversion Site
-
Godsave, S. F., H. Wille, P. Kujala, D. Latawiec, S. J. Dearmond, A. Serban, S. B. Prusiner & P. J. Peters: Cryo-Immunogold Electron Microscopy for Prions: Toward Identification of a Conversion Site. J Neurosci, 28, 12489-12499 (2008)
-
(2008)
J Neurosci
, vol.28
, pp. 12489-12499
-
-
Godsave, S.F.1
Wille, H.2
Kujala, P.3
Latawiec, D.4
Dearmond, S.J.5
Serban, A.6
Prusiner, S.B.7
Peters, P.J.8
-
51
-
-
0041888516
-
Trafficking of prion proteins through a caveolae-mediated endosomal pathway
-
DOI 10.1083/jcb.200304140
-
Peters, P. J., A. Mironov, Jr., D. Peretz, E. van Donselaar, E. Leclerc, S. Erpel, S. J. DeArmond, D. R. Burton, R. A. Williamson, M. Vey & S. B. Prusiner: Trafficking of prion proteins through a caveolae-mediated endosomal pathway. J Cell Biol, 162, 703-17 (2003) (Pubitemid 37022947)
-
(2003)
Journal of Cell Biology
, vol.162
, Issue.4
, pp. 703-717
-
-
Peters, P.J.1
Mironov Jr., A.2
Peretz, D.3
Van Donselaar, E.4
Leclerc, E.5
Erpel, S.6
DeArmond, S.J.7
Burton, D.R.8
Williamson, R.A.9
Vey, M.10
Prusiner, S.B.11
-
52
-
-
73349140865
-
Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulumderived chaperones
-
Watts, J. C., H. Huo, Y. Bai, S. Ehsani, A. H. Won, T. Shi, N. Daude, A. Lau, R. Young, L. Xu, G. A. Carlson, D. Williams, D. Westaway & G. Schmitt-Ulms: Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulumderived chaperones. PLoS Pathog, 5, e1000608 (2009)
-
(2009)
PLoS Pathog
, vol.5
-
-
Watts, J.C.1
Huo, H.2
Bai, Y.3
Ehsani, S.4
Won, A.H.5
Shi, T.6
Daude, N.7
Lau, A.8
Young, R.9
Xu, L.10
Carlson, G.A.11
Williams, D.12
Westaway, D.13
Schmitt-Ulms, G.14
-
53
-
-
77955655747
-
Mapping the interaction site of prion protein and Sho
-
Jiayu, W., H. Zhu, X. Ming, W. Xiong, W. Songbo, S. Bocui, L. Wensen, L. Jiping, M. Keying, L. Zhongyi & G. Hongwei: Mapping the interaction site of prion protein and Sho. Mol Biol Rep, 37, 2295-300 (2010)
-
(2010)
Mol Biol Rep
, vol.37
, pp. 2295-2300
-
-
Jiayu, W.1
Zhu, H.2
Ming, X.3
Xiong, W.4
Songbo, W.5
Bocui, S.6
Wensen, L.7
Jiping, L.8
Keying, M.9
Zhongyi, L.10
Hongwei, G.11
-
54
-
-
18444397736
-
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection
-
DOI 10.1093/emboj/cdf325
-
Zanata, S. M., M. H. Lopes, A. F. Mercadante, G. N. Hajj, L. B. Chiarini, R. Nomizo, A. R. Freitas, A. L. Cabral, K. S. Lee, M. A. Juliano, E. de Oliveira, S. G. Jachieri, A. Burlingame, L. Huang, R. Linden, R. R. Brentani & V. R. Martins: Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. Embo J, 21, 3307-16 (2002) (Pubitemid 34760563)
-
(2002)
EMBO Journal
, vol.21
, Issue.13
, pp. 3307-3316
-
-
Zanata, S.M.1
Lopes, M.H.2
Mercadante, A.F.3
Hajj, G.N.M.4
Chiarini, L.B.5
Nomizo, R.6
Freitas, A.R.O.7
Cabral, A.L.B.8
Lee, K.S.9
Juliano, M.A.10
De Oliveira, E.11
Jachieri, S.G.12
Burlingame, A.13
Huang, L.14
Linden, R.15
Brentani, R.R.16
Martins, V.R.17
-
55
-
-
14044265063
-
A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein
-
DOI 10.1074/jbc.C400560200
-
Uelhoff, A., J. Tatzelt, A. Aguzzi, K. F. Winklhofer & C. Haass: A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein. J Biol Chem, 280, 5137-40 (2005) (Pubitemid 40279982)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.7
, pp. 5137-5140
-
-
Uelhoff, A.1
Tatzelt, J.2
Aguzzi, A.3
Winklhofer, K.F.4
Haass, C.5
-
56
-
-
22844451837
-
C complex that leads to prion propagation
-
DOI 10.1074/jbc.M413441200
-
Norstrom, E. M. & J. A. Mastrianni: The AGAAAAGA palindrome in PrP is required to generate a productive PrPSc-PrPC complex that leads to prion propagation. J Biol Chem, 280, 27236-43 (2005) (Pubitemid 41040763)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.29
, pp. 27236-27243
-
-
Norstrom, E.M.1
Mastrianni, J.A.2
-
57
-
-
0027483615
-
Neurotoxicity of a prion protein fragment
-
DOI 10.1038/362543a0
-
Forloni, G., N. Angeretti, R. Chiesa, E. Monzani, M. Salmona, O. Bugiani & F. Tagliavini: Neurotoxicity of a prion protein fragment. Nature, 362, 543-6 (1993) (Pubitemid 23113029)
-
(1993)
Nature
, vol.362
, Issue.6420
, pp. 543-546
-
-
Forloni, G.1
Angeretti, N.2
Chiesa, R.3
Monzani, E.4
Salmona, M.5
Bugiani, O.6
Tagliavini, F.7
-
58
-
-
0024473899
-
Pro-Leu change at position 102 of prion protein is the most common but not the sole mutation related to Gerstmann-Straussler syndrome
-
DOI 10.1016/0006-291X(89)92317-6
-
Doh-ura, K., J. Tateishi, H. Sasaki, T. Kitamoto & Y. Sakaki: Pro-leu change at position 102 of prion protein is the most common but not the sole mutation related to Gerstmann-Straussler syndrome. Biochem Biophys Res Commun, 163, 974-9 (1989) (Pubitemid 19236945)
-
(1989)
Biochemical and Biophysical Research Communications
, vol.163
, Issue.2
, pp. 974-979
-
-
Doh-ura, K.1
Tateishi, J.2
Sasaki, H.3
Kitamoto, T.4
Sakaki, Y.5
-
59
-
-
0037646565
-
The PrP-like protein doppel binds copper
-
DOI 10.1074/jbc.M210875200
-
Qin, K., J. Coomaraswamy, P. Mastrangelo, Y. Yang, S. Lugowski, C. Petromilli, S. B. Prusiner, P. E. Fraser, J. M. Goldberg, A. Chakrabartty & D. Westaway: The PrP-like protein Doppel binds copper. J Biol Chem, 278, 8888-96 (2003) (Pubitemid 36800364)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.11
, pp. 8888-8896
-
-
Qin, K.1
Coomaraswamy, J.2
Mastrangelo, P.3
Yang, Y.4
Lugowski, S.5
Petromilli, C.6
Prusiner, S.B.7
Fraser, P.E.8
Goldberg, J.M.9
Chakrabartty, A.10
Westaway, D.11
-
60
-
-
79959627373
-
Distribution of the Shadoo protein in the ovine brain assessed by immunohistochemistry
-
Lampo, E., W. Van den Broeck, N. Willemarck, M. Van Poucke, C. R. Casteleyn, W. De Spiegelaere, A. Van Zeveren & L. J. Peelman: Distribution of the Shadoo protein in the ovine brain assessed by immunohistochemistry. Res Vet Sci (2010)
-
(2010)
Res Vet Sci
-
-
Lampo, E.1
Van Den Broeck, W.2
Willemarck, N.3
Van Poucke, M.4
Casteleyn, C.R.5
De Spiegelaere, W.6
Van Zeveren, A.7
Peelman, L.J.8
-
62
-
-
34249937435
-
The prion protein family: Diversity, rivalry, and dysfunction
-
DOI 10.1016/j.bbadis.2007.05.001, PII S092544390700107X, Prion-Related Disorders
-
Watts, J. C. & D. Westaway: The prion protein family: Diversity, rivalry, and dysfunction. Biochim Biophys Acta, 1772, 654-72 (2007) (Pubitemid 46880210)
-
(2007)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1772
, Issue.6
, pp. 654-672
-
-
Watts, J.C.1
Westaway, D.2
-
63
-
-
70349669073
-
Evolutionary descent of prion genes from the ZIP family of metal ion transporters
-
Schmitt-Ulms, G., S. Ehsani, J. C. Watts, D. Westaway & H. Wille: Evolutionary descent of prion genes from the ZIP family of metal ion transporters. PLoS ONE, 4, e7208 (2009)
-
(2009)
PLoS ONE
, vol.4
-
-
Schmitt-Ulms, G.1
Ehsani, S.2
Watts, J.C.3
Westaway, D.4
Wille, H.5
-
64
-
-
33846543360
-
Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125
-
DOI 10.1038/sj.emboj.7601507, PII 7601507
-
Li, A., H. M. Christensen, L. R. Stewart, K. A. Roth, R. Chiesa & D. A. Harris: Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125. Embo J, 26, 548-58 (2007) (Pubitemid 46160954)
-
(2007)
EMBO Journal
, vol.26
, Issue.2
, pp. 548-558
-
-
Li, A.1
Christensen, H.M.2
Stewart, L.R.3
Roth, K.A.4
Chiesa, R.5
Harris, D.A.6
-
65
-
-
0035877756
-
Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695
-
DOI 10.1074/jbc.M100710200
-
Chishti, M. A., D. S. Yang, C. Janus, A. L. Phinney, P. Horne, J. Pearson, R. Strome, N. Zuker, J. Loukides, J. French, S. Turner, G. Lozza, M. Grilli, S. Kunicki, C. Morissette, J. Paquette, F. Gervais, C. Bergeron, P. E. Fraser, G. A. Carlson, P. S. George-Hyslop & D. Westaway: Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem, 276, 21562-70 (2001) (Pubitemid 37413154)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.24
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.-S.2
Janus, C.3
Phinney, A.L.4
Horne, P.5
Pearson, J.6
Strome, R.7
Zuker, N.8
Loukides, J.9
French, J.10
Turner, S.11
Lozza, G.12
Grilli, M.13
Kunicki, S.14
Morissette, C.15
Paquette, J.16
Gervais, F.17
Bergeron, C.18
Fraser, P.E.19
Carlson, G.A.20
St. George-Hyslop, P.21
Westawaya, D.22
more..
-
66
-
-
77249092467
-
Agent-specific Shadoo responses in transmissible encephalopathies
-
Miyazawa, K. & L. Manuelidis: Agent-specific Shadoo responses in transmissible encephalopathies. J Neuroimmune Pharmacol, 5, 155-63 (2010)
-
(2010)
J Neuroimmune Pharmacol
, vol.5
, pp. 155-163
-
-
Miyazawa, K.1
Manuelidis, L.2
-
67
-
-
67651149482
-
Shadoo (Sprn) and prion disease incubation time in mice
-
Lloyd, S. E., J. Grizenkova, H. Pota & J. Collinge: Shadoo (Sprn) and prion disease incubation time in mice. Mamm Genome, 20 (6), 367-74 (2009)
-
(2009)
Mamm Genome
, vol.20
, Issue.6
, pp. 367-374
-
-
Lloyd, S.E.1
Grizenkova, J.2
Pota, H.3
Collinge, J.4
-
68
-
-
68349128297
-
Frequent missense and insertion/deletion polymorphisms in the ovine Shadoo gene parallel species-specific variation in PrP
-
Daude, N., S. Wohlgemuth, E. Rogaeva, A. H. Farid, M. Heaton & D. Westaway: Frequent missense and insertion/deletion polymorphisms in the ovine Shadoo gene parallel species-specific variation in PrP. PLoS ONE, 4, e6538 (2009)
-
(2009)
PLoS ONE
, vol.4
-
-
Daude, N.1
Wohlgemuth, S.2
Rogaeva, E.3
Farid, A.H.4
Heaton, M.5
Westaway, D.6
-
69
-
-
57349086072
-
Association of a null allele of SPRN with variant Creutzfeldt-Jakob disease
-
Beck, J. A., T. A. Campbell, G. Adamson, M. Poulter, J. B. Uphill, E. Molou, J. Collinge & S. Mead: Association of a null allele of SPRN with variant Creutzfeldt-Jakob disease. J Med Genet, 45, 813-7 (2008)
-
(2008)
J Med Genet
, vol.45
, pp. 813-817
-
-
Beck, J.A.1
Campbell, T.A.2
Adamson, G.3
Poulter, M.4
Uphill, J.B.5
Molou, E.6
Collinge, J.7
Mead, S.8
-
70
-
-
70949091205
-
A novel protective prion protein variant that colocalizes with kuru exposure
-
Mead, S., J. Whitfield, M. Poulter, P. Shah, J. Uphill, T. Campbell, H. Al-Dujaily, H. Hummerich, J. Beck, C. A. Mein, C. Verzilli, J. Whittaker, M. P. Alpers & J. Collinge: A novel protective prion protein variant that colocalizes with kuru exposure. N Engl J Med, 361, 2056-65 (2009)
-
(2009)
N Engl J Med
, vol.361
, pp. 2056-2065
-
-
Mead, S.1
Whitfield, J.2
Poulter, M.3
Shah, P.4
Uphill, J.5
Campbell, T.6
Al-Dujaily, H.7
Hummerich, H.8
Beck, J.9
Mein, C.A.10
Verzilli, C.11
Whittaker, J.12
Alpers, M.P.13
Collinge, J.14
-
71
-
-
77952100567
-
Genomic assessment of the evolution of the prion protein gene family in vertebrates
-
Harrison, P. M., A. Khachane & M. Kumar: Genomic assessment of the evolution of the prion protein gene family in vertebrates. Genomics, 95, 268-77 (2010)
-
(2010)
Genomics
, vol.95
, pp. 268-277
-
-
Harrison, P.M.1
Khachane, A.2
Kumar, M.3
-
72
-
-
0242412541
-
Mutational Analysis of Topological Determinants in Prion Protein (PrP) and Measurement of Transmembrane and Cytosolic PrP during Prion Infection
-
DOI 10.1074/jbc.M307833200
-
Stewart, R. S. & D. A. Harris: Mutational analysis of topological determinants in prion protein (PrP) and measurement of transmembrane and cytosolic PrP during prion infection. J Biol Chem, 278, 45960-8 (2003) (Pubitemid 37432743)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.46
, pp. 45960-45968
-
-
Stewart, R.S.1
Harris, D.A.2
-
73
-
-
77649213673
-
Generating a prion with bacterially expressed recombinant prion protein
-
Wang, F., X. Wang, C. G. Yuan & J. Ma: Generating a prion with bacterially expressed recombinant prion protein. Science, 327, 1132-5 (2010)
-
(2010)
Science
, vol.327
, pp. 1132-1135
-
-
Wang, F.1
Wang, X.2
Yuan, C.G.3
Ma, J.4
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