A novel protective prion protein variant that colocalizes with kuru exposure

New England Journal of Medicine

Volumn 361, Issue 21, 2009, Pages 2056-2065

  Mead, Simon ^a   Whitfield, Jerome ^a   Poulter, Mark ^a   Shah, Paresh ^a   Uphill, James ^a   Campbell, Tracy ^a   Al Dujaily, Huda ^a   Hummerich, Holger ^a   Beck, Jon ^a   Mein, Charles A ^b   Verzilli, Claudio ^c   Whittaker, John ^c,d   Alpers, Michael P ^a,d,e   Collinge, John ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

^e CURTIN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

METHIONINE; PRION PROTEIN;

ADULT; ALLELE; ARTICLE; CODON; CONTROLLED STUDY; EPIDEMIC; FEMALE; GEOGRAPHIC DISTRIBUTION; HETEROZYGOTE; HUMAN; KURU; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PAPUA NEW GUINEA; PREVALENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN VARIANT;

ADOLESCENT; ADULT; AGED; CANNIBALISM; DISEASE OUTBREAKS; FEMALE; GENE FREQUENCY; GENETIC FITNESS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; KURU; MALE; MIDDLE AGED; PAPUA NEW GUINEA; POLYMORPHISM, GENETIC; PRIONS; YOUNG ADULT;

EID: 70949091205     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa0809716     Document Type: Article

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