The PrP-like protein doppel binds copper

Journal of Biological Chemistry

Volumn 278, Issue 11, 2003, Pages 8888-8896

  Qin, Kefeng ^a   Coomaraswamy, Janaky ^a   Mastrangelo, Peter ^a   Yang, Ying ^b   Lugowski, Stan ^b   Petromilli, Chris ^d   Prusiner, Stanley B ^d   Fraser, Paul E ^a,c   Goldberg, Jonathan M ^e   Chakrabartty, Avijit ^c   Westaway, David ^a,c,f  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^f CRND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; DATA REDUCTION; FLUORESCENCE; FREE RADICALS; MASS SPECTROMETRY; QUENCHING;

COPPER-BINDING DOMAIN;

PROTEINS;

COPPER; DIETHYL PYROCARBONATE; PRION PROTEIN; PROTEIN; PROTEIN DOPPEL; UNCLASSIFIED DRUG; 3 NITROTYROSINE; 3-NITROTYROSINE; CARBON; CHYMOTRYPSIN; DRUG DERIVATIVE; FREE RADICAL; HISTIDINE; NITROGEN; PEPTIDE; PRND PROTEIN, MOUSE; RECOMBINANT PROTEIN; TYROSINE;

ALPHA HELIX; ARTICLE; BINDING SITE; EQUILIBRIUM DIALYSIS; FLUORESCENCE; IN VIVO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METAL BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN STABILITY; TESTIS; ANIMAL; BINDING COMPETITION; CHEMISTRY; CIRCULAR DICHROISM; DOSE RESPONSE; KINETICS; MASS SPECTROMETRY; METABOLISM; PRION; SPECTROFLUOROMETRY; WESTERN BLOTTING;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BLOTTING, WESTERN; CARBON; CHYMOTRYPSIN; CIRCULAR DICHROISM; COPPER; DIETHYL PYROCARBONATE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; HISTIDINE; KINETICS; MICE; NITROGEN; PEPTIDES; PRIONS; PROTEIN BINDING; PROTEINS; PRPC PROTEINS; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TYROSINE;

EID: 0037646565     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210875200     Document Type: Article

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