β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway

Journal of Immunology

Volumn 186, Issue 7, 2011, Pages 4443-4454

  Qian, Li ^a,b   Wu, Hungming ^b   Chen, Shih Heng ^b   Zhang, Dan ^b   Ali, Syed F ^c   Peterson, Lynda ^a   Wilson, Belinda ^b   Lu, Ru Band ^d   Hong, Jau Shyong ^b   Flood, Patrick M ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BAMBUTEROL; BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN 2; CLENBUTEROL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DOPAMINE; FORMOTEROL; G PROTEIN COUPLED RECEPTOR; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; SALMETEROL; SUPEROXIDE; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CONTINUOUS INFUSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DOSE COMPARISON; EMBRYO; ENZYME PHOSPHORYLATION; GLIA CELL; INHIBITION KINETICS; LOW DRUG DOSE; MALE; MICROGLIA; MOUSE; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ANIMALS; CELLS, CULTURED; COCULTURE TECHNIQUES; DOPAMINE; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NEURAL INHIBITION; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; RATS; RATS, INBRED F344; SIGNAL TRANSDUCTION;

EID: 79955000817     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002449     Document Type: Article

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