Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 47, 2007, Pages 18754-18759

  Ghosh, Anamitra ^a   Roy, Avik ^a   Liu, Xiaojuan ^b   Kordower, Jeffrey H ^a   Mufson, Elliott J ^a   Hartley, Dean M ^a   Ghosh, Sankar ^c   Mosley, R Lee ^d   Gendelman, Howard E ^d   Pahan, Kalipada ^a,b  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

MPTP; NBD peptides; Neurodegeneration

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR RELA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; GLIA CELL; LOCOMOTION; MALE; MESENCEPHALON; MOUSE; NERVE DEGENERATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRIATONIGRAL DEGENERATION;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; BINDING SITES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DOPAMINE; GENE EXPRESSION REGULATION; HUMANS; MALE; MESENCEPHALON; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; NF-KAPPA B; PARKINSON DISEASE; PEPTIDES;

MUS;

EID: 36749015082     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0704908104     Document Type: Article

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