Superoxide dismutase 1 knockdown induces oxidative stress and DNA methylation loss in the prostate

Epigenetics

Volumn 5, Issue 5, 2010, Pages

  Bhusari, Sachin S ^a   Dobosy, Joseph R ^a   Fu, Vivian ^a   Almassi, Nima ^a   Oberley, Terry ^a   Jarrard, David F ^a,b  

^a UNIVERSITY OF WISCONSIN   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

DNA methylation; H19; Igf2; Oxidative stress; Prostate cancer; Sod1; Superoxide dismutase 1

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; COPPER ZINC SUPEROXIDE DISMUTASE; DNA; RNA H19; SOMATOMEDIN B; TRANSCRIPTION FACTOR CTCF;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BODY WEIGHT; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIVER; LOSS OF FUNCTION MUTATION; MAMMAL; MOUSE; MUTANT; NONHUMAN; ONCOGENE; OXIDATIVE STRESS; PROMOTER REGION; PROSTATE;

MAMMALIA; MUS;

EID: 77954679759     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.5.5.11853     Document Type: Article

References (54)

1. Gluckman PD, Hanson MA, Buklijas T, Low FM, Beedle AS. Epigenetic mechanisms that underpin metabolic and cardiovascular diseases. Nat Rev Endocrinol 2009; 5:401.
2. Calvanese V, Lara E, Kahn A, Fraga MF. The role of epigenetics in aging and age-related diseases. Ageing Res Rev 2009; 8:268.
3. Dobosy JR, Roberts JL, Fu VX, Jarrard DF. The expanding role of epigenetics in the development, diagnosis and treatment of prostate cancer and benign prostatic hyperplasia. J Urol 2007; 177:822-31.
4. Waterland RA, Jirtle RL. Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. Nutrition 2004; 20:63.
5. Weitzman SA, Turk PW, Milkowski DH, Kozlowski K. Free radical adducts induce alterations in DNA cytosine methylation. P Natl Acad Sci USA 1994; 91:1261-4.
6. Turk PW, Laayoun A, Smith SS, Weitzman SA. DNA adduct 8-hydroxyl-2'-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase. Carcinogenesis 1995; 16:1253-5.
7. Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol 1997; 82:291-5.
8. Fleshner NE, Klotz LH. Diet, Androgens, Oxidative Stress and Prostate Cancer Susceptibility. Cancer Metast Rev 1998; 17:325.
9. Orr WC, Sohal RS. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 1994; 263:1128-30.
10. Gutteridge JMC, Halliwell B. Free radicals in biology and medicine. Oxford University Press Oxford 2003.
11. De Marzo AM, Marchi VL, Epstein JI, Nelson WG. Proliferative Inflammatory Atrophy of the Prostate: Implications for Prostatic Carcinogenesis. Am J Pathol 1999; 155:1985-92.
12. Morrissey C, Buser A, Scolaro J, O'Sullivan J, Moquin A, Tenniswood M. Changes in Hormone Sensitivity in the Ventral Prostate of Aging Sprague-Dawley Rats. J Androl 2002; 23:341-51.
13. Terry DO, Weixiong Z, Luke IS, Larry WO. Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium. The Prostate 2000; 44:144-55.
14. Malins DC, Johnson PM, Wheeler TM, Barker EA, Polissar NL, Vinson MA. Age-related Radical-induced DNA Damage Is Linked to Prostate Cancer. Cancer Res 2001; 61:6025-8.
15. Tunc O, Tremellen K. Oxidative DNA damage impairs global sperm DNA methylation in infertile men. J Assist Reprod Gen 2009; 26:537.
16. Guz J, Foksinski M, Siomek A, Gackowski D, Rozalski R, Dziaman T, et al. The relationship between 8-oxo-7, 8-dihydro-2-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas. Mutat Res-Fund Mol M 2008; 640:170-3.
17. McCord JM, Fridovich I. Superoxide Dismutase. An Enzymatic Function for Erythrocuprein (Hemocuprein). J Biol Chem 1969; 244:6049-55.
18. Weisiger RA, Fridovich I. Mitochondrial Superoxide Dismutase. Site of Synthesis and Intramitochondrial Localization. J Biol Chem 1973; 248:4793-6.
19. Huang T-T, Yasunami M, Carlson EJ, Gillespie AM, Reaume AG, Hoffman EK, et al. Superoxide-Mediated Cytotoxicity in Superoxide Dismutase-Deficient Fetal Fibroblasts. Arch Biochem Biophys 1997; 344:424.
20. Elchuri S, Oberley TD, Qi W, Eisenstein RS, Jackson Roberts L, Van Remmen H, et al. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene 2005; 24:367.
21. Joseph R. Dobosy, Vivian X. Fu, Joshua A. Desotelle, Rajini Srinivasan, Michelle L. Kenowski, Nima Almassi, et al. A methyl-deficient diet modifies histone methylation and alters Igf2 and H19 repression in the prostate. The Prostate 2008; 68:1187-95.
22. Hu J-F, Nguyen PH, Pham NV, Vu TH, Hoffman AR. Modulation of Igf2 Genomic Imprinting in Mice Induced by 5-Azacytidine, an Inhibitor of DNA Methylation. Mol Endocrinol 1997; 11:1891-8.
23. Ting-Ting Huang EJCIRAMGHKCJE. The Use of Transgenic and Mutant Mice to Study Oxygen Free Radical Metabolism. Ann NY Acad Sci 1999; 893:95-112.
24. Beauchamp C, Fridovich I. Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels. Anal Biochem 1971; 44:276.
25. Muller FL, Song W, Liu Y, Chaudhuri A, Pieke-Dahl S, Strong R, et al. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radical Bio Med 2006; 40:1993.
26. Ayala-Torres S, Chen Y, Svoboda T, Rosenblatt J, Van Houten B. Analysis of Gene-Specific DNA Damage and Repair Using Quantitative Polymerase Chain Reaction. Methods 2000; 22:135.
27. Santos JH, Mandavilli BS, Houten B. Measuring Oxidative mtDNA Damage and Repair Using Quantitative PCR. Mitochondr DNA 2002; 159.
28. Santos JH, Meyer JN, Mandavilli BS, Houten B. Quantitative PCR-Based Measurement of Nuclear and Mitochondrial DNA Damage and Repair in Mammalian Cells. DNA Repair Protocols 2006; 183.
29. Wu Q, Ohsako S, Ishimura R, Suzuki JS, Tohyama C. Exposure of Mouse Preimplantation Embryos to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Alters the Methylation Status of Imprinted Genes H19 and Igf2. Biol Reprod 2004; 70:1790-7.
30. Nonogaki T, Noda Y, Narimoto K, Shiotani M, Mori T, Matsuda T, et al. Localization of CuZn-superoxide dismutase in the human male genital organs. Hum Reprod 1992; 7:81-5.
31. Sabine T, Ralf N, Axel E, Harald S, Michael K. Evaluation of average life span of epithelial and stromal cells of human prostate by superoxide dismutase activity. The Prostate 1989; 15:263-71.
32. Pierson MG, Gray BH. Superoxide dismutase activity in the cochlea. Hearing Res 1982; 6:141.
33. Ghatak S, Ho SM. Age-Related Changes in the Activities of Antioxidant Enzymes and Lipid Peroxidation Status in Ventral and Dorsolateral Prostate Lobes of Noble Rats. Biochem Bioph Res Co 1996; 222:362.
34. David GB, Erik EA, Rohini S, Ailin S, Junqi Q, Regina MS, et al. Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer. Cancer 2000; 89:123-34.
35. Oberley TD. Oxidative Damage and Cancer. Am J Pathol 2002; 160:403-8.
36. Neville NCT, Abraham N, Robert RM, Grace K, Liat L, Andrew S, et al. Differential attenuation of oxidative/nitrosative injuries in early prostatic neoplastic lesions in TRAMP mice by dietary antioxidants. The Prostate 2006; 66:57-69.
37. Ouyang X, DeWeese TL, Nelson WG, Abate-Shen C. Loss-of-Function of Nkx3.1 Promotes Increased Oxidative Damage in Prostate Carcinogenesis. Cancer Res 2005; 65:6773-9.
38. Hussain SP, Harris CC. Molecular Epidemiology of Human Cancer: Contribution of Mutation Spectra Studies of Tumor Suppressor Genes. Cancer Res 1998; 58:4023-37.
39. Shibutani S, Takeshita M, Grollman AP. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 1991; 349:431.
40. Loeb LA. Mutator Phenotype May Be Required for Multistage Carcinogenesis. Cancer Res 1991; 51:3075-9.
41. Franco R, Schoneveld O, Georgakilas AG, Panayiotidis MI. Oxidative stress, DNA methylation and carcinogenesis. Cancer Lett 2008; 266:6.
42. Waterland RA, Jirtle RL. Transposable Elements: Targets for Early Nutritional Effects on Epigenetic Gene Regulation. Mol Cell Biol 2003; 23:5293-300.
43. Pogribny IP, James SJ, Jernigan S, Pogribna M. Genomic hypomethylation is specific for preneoplastic liver in folate/methyl deficient rats and does not occur in non-target tissues. Mutat Res-Fund Mol M 2004; 548:53.
44. Waterland RA, Lin J-R, Smith CA, Jirtle RL. Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus. Hum Mol Genet 2006; 15:705-16.
45. Ling JQ, Li T, Hu JF, Vu TH, Chen HL, Qiu XW, et al. CTCF Mediates Interchromosomal Colocalization Between Igf2/H19 and Wsb1/Nf1. Science 2006; 312:269-72.
46. Turk PW, Weitzman SA. Free Radical Dna Adduct 8-Oh-Deoxyguanosine Affects Activity of Hp a II and Msp I Restriction Endonucleases. Free Radical Res 1995; 23:255-8.
47. James SJ, Pogribny IP, Pogribna M, Miller BJ, Jernigan S, Melnyk S. Mechanisms of DNA Damage, DNA Hypomethylation, and Tumor Progression in the Folate/ Methyl-Deficient Rat Model of Hepatocarcinogenesis. J Nutr 2003; 133:3740-7.
48. Valinluck V, Tsai H-H, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucl Acids Res 2004; 32:4100-8.
49. Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, et al. Induction of Tumors in Mice by Genomic Hypomethylation. Science 2003; 300:489-92.
50. Wachsman JT. DNA methylation and the association between genetic and epigenetic changes: relation to carcinogenesis. Mutat Res-Fund Mol M 1997; 375:1.
51. Klein EA, Casey G, Silverman R. Genetic susceptibility and oxidative stress in prostate cancer: Integrated model with implications for prevention. Urology 2006; 68:1145.
52. Herceg Z. Epigenetics and cancer: towards an evaluation of the impact of environmental and dietary factors. Mutagenesis 2007; 22:91-103.
53. Yegnasubramanian S, Kowalski J, Gonzalgo ML, Zahurak M, Piantadosi S, Walsh PC, et al. Hypermethylation of CpG Islands in Primary and Metastatic Human Prostate Cancer. Cancer Res 2004; 64:1975-86.
54. Chaiswing L, Bourdeau-Heller JM, Zhong W, Oberley TD. Characterization of redox state of two human prostate carcinoma cell lines with different degrees of aggressiveness. Free Radical Bio and Med 2007; 43:202.