메뉴 건너뛰기




Volumn 42, Issue 5, 2011, Pages 540-546

Curcumin activates Wnt/β-catenin signaling pathway through inhibiting the activity of GSK-3β in APPswe transfected SY5Y cells

Author keywords

Catenin; A ; Alzheimer's disease; Curcumin; GSK 3

Indexed keywords

BETA CATENIN; CURCUMIN; CYCLIN D1;

EID: 79954628955     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.02.009     Document Type: Article
Times cited : (109)

References (40)
  • 2
    • 33745301487 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β and Alzheimer's disease: Pathophysiological and therapeutic significance
    • Y. Balaramana, A.R. Limayea, A.I. Leveyb, and S. Srinivasan Glycogen synthase kinase 3β and Alzheimer's disease: pathophysiological and therapeutic significance Cell. Mol. Life Sci. 2006 1 10
    • (2006) Cell. Mol. Life Sci. , pp. 1-10
    • Balaramana, Y.1    Limayea, A.R.2    Leveyb, A.I.3    Srinivasan, S.4
  • 3
    • 34548036227 scopus 로고    scopus 로고
    • Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
    • DOI 10.1038/nrn2194, PII NRN2194
    • C. Ballatore, V.M. Lee, and J.Q. Trojanowski Tau-mediated neurodegeneration in Alzheimer's disease and related disorders Nat. Rev. Neurosci. 8 9 2007 663 672 (Pubitemid 47283144)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.9 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.-Y.2    Trojanowski, J.Q.3
  • 4
    • 37649023273 scopus 로고    scopus 로고
    • A beta-arrestin 2 signaling complex mediates lithium action on behavior
    • J.M. Beaulieu, S. Marion, and R.M. Rodriguiz A beta-arrestin 2 signaling complex mediates lithium action on behavior Cell 132 1 2008 125 136
    • (2008) Cell , vol.132 , Issue.1 , pp. 125-136
    • Beaulieu, J.M.1    Marion, S.2    Rodriguiz, R.M.3
  • 5
    • 0036667223 scopus 로고    scopus 로고
    • Interactions between GSK3β and caspase signalling pathways during NGF deprivation induced cell death
    • R.V. Bhat, S. Leonov, and J. Luthman Interactions between GSK3beta and caspase signalling pathways during NGF deprivation induced cell death J. Alzheimer Dis. 4 4 2002 291 301 (Pubitemid 35257147)
    • (2002) Journal of Alzheimer's Disease , vol.4 , Issue.4 , pp. 291-301
    • Bhat, R.V.1    Leonov, S.2    Luthman, J.3    Scott, C.W.4    Lee, C.-M.5
  • 6
    • 67649392145 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase by curcumin: Investigation by simulated molecular docking and subsequent in vitro/in vivo evaluation
    • Y. Bustanji, M.O. Taha, I.M. Almasri, M.A. Al-Ghussein, M.K. Mohammad, and H.S. Alkhatib Inhibition of glycogen synthase kinase by curcumin: investigation by simulated molecular docking and subsequent in vitro/in vivo evaluation Enzyme Inhib. Med. Chem. 243 1 2008 771 778
    • (2008) Enzyme Inhib. Med. Chem. , vol.243 , Issue.1 , pp. 771-778
    • Bustanji, Y.1    Taha, M.O.2    Almasri, I.M.3    Al-Ghussein, M.A.4    Mohammad, M.K.5    Alkhatib, H.S.6
  • 7
    • 13844306722 scopus 로고    scopus 로고
    • Activation of PPARγ by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR
    • A. Chen, and J. Xu Activation of PPARγ by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR Am. J. Physiol. Gastrointest. Liver Physiol. 288 3 2005 G447 G456
    • (2005) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.288 , Issue.3
    • Chen, A.1    Xu, J.2
  • 8
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-tasking kinase
    • DOI 10.1242/jcs.00384
    • B.W. Doble, and J.R. Woodgett GSK-3: tricks of the trade for a multi-tasking kinase J. Cell Sci. 116 2003 1175 1186 (Pubitemid 36410657)
    • (2003) Journal of Cell Science , vol.116 , Issue.7 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 10
    • 0034969088 scopus 로고    scopus 로고
    • A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation
    • DOI 10.1016/S1097-2765(01)00253-2
    • S. Frame, P. Cohen, and R.M. Biondi A common phosphate bingding site explains the unique substrate specificity of GSK-3 and its inactivation by phosphorylation Mol. Cell 7 6 2001 1321 1327 (Pubitemid 32607364)
    • (2001) Molecular Cell , vol.7 , Issue.6 , pp. 1321-1327
    • Frame, S.1    Cohen, P.2    Biondi, R.M.3
  • 11
    • 0033602475 scopus 로고    scopus 로고
    • HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IκB and β-catenin
    • S.Y. Fuchs, A. Chen, Y. Xiong, Z.Q. Pan, and Z. Ronai HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin Oncogene 18 12 1999 2039 2046 (Pubitemid 29178572)
    • (1999) Oncogene , vol.18 , Issue.12 , pp. 2039-2046
    • Fuchs, S.Y.1    Chen, A.2    Xiong, Y.3    Pan, Z.-Q.4    Ronai, Z.5
  • 12
    • 9644275641 scopus 로고    scopus 로고
    • Signal transduction during amyloid-β-peptide neurotoxicity: Role in Alzheimer disease
    • DOI 10.1016/j.brainresrev.2004.07.018, PII S0165017304001055, Chemical and Electrical Synapses
    • R.A. Fuentealba, G. Farias, and J. Scheu Signal transduction during amyloid-beta peptide neurotoxicity role in Alzheimer disease Brain Res. Brain Res. Rev. 47 1-3 2004 275 289 (Pubitemid 39574325)
    • (2004) Brain Research Reviews , vol.47 , Issue.1-3 , pp. 275-289
    • Fuentealba, R.A.1    Farias, G.2    Scheu, J.3    Bronfman, M.4    Marzolo, M.P.5    Inestrosa, N.C.6
  • 13
    • 27744531603 scopus 로고    scopus 로고
    • Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability
    • S. Geo, K. Zen, and B. Lia Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability J. Biol. Chem. 280 43 2005 36007 36012
    • (2005) J. Biol. Chem. , vol.280 , Issue.43 , pp. 36007-36012
    • Geo, S.1    Zen, K.2    Lia, B.3
  • 14
    • 25144472262 scopus 로고    scopus 로고
    • Phospho-β-catenin accumulation in Alzheimer's disease and in aggresomes attributable to proteasome dysfunction
    • M. Ghanevati, and C.A. Miller Phospho-beta-catenin accumulation in Alzheimer's disease and in aggresomes attributable to proteasome dysfunction J. Mol. Neurosci. 25 1 2005 79 94 (Pubitemid 41389368)
    • (2005) Journal of Molecular Neuroscience , vol.25 , Issue.1 , pp. 79-94
    • Ghanevati, M.1    Miller, C.A.2
  • 15
    • 66149127297 scopus 로고    scopus 로고
    • Mutant presenilin 1 increases the expression and the activity of bace1
    • L. Giliberto, R. Borghi, and A. Piccini Mutant presenilin 1 increases the expression and the activity of bace1 J. Biol. Chem. 284 2009 9027 9038
    • (2009) J. Biol. Chem. , vol.284 , pp. 9027-9038
    • Giliberto, L.1    Borghi, R.2    Piccini, A.3
  • 16
    • 33846101613 scopus 로고    scopus 로고
    • Filling the gaps in the Aβ cascade hypothesis of Alzheimer's disease
    • DOI 10.2174/156720506779025189
    • T.E. Golde, D. Dickson, and M. Hutton Filling the gaps in the Abeta cascade hypothesis of Alzheimer's disease Curr. Alzheimers Res. 3 5 2006 421 430 (Pubitemid 46066421)
    • (2006) Current Alzheimer Research , vol.3 , Issue.5 , pp. 421-430
    • Golde, T.E.1    Dickson, D.2    Hutton, M.3
  • 17
    • 73549106551 scopus 로고    scopus 로고
    • Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway
    • T. Hamaguchi, K. Ono, A. Murase, and M. Yamada Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway Am. J. Pathol. 175 6 2009 2557 2565
    • (2009) Am. J. Pathol. , vol.175 , Issue.6 , pp. 2557-2565
    • Hamaguchi, T.1    Ono, K.2    Murase, A.3    Yamada, M.4
  • 18
    • 58549104760 scopus 로고    scopus 로고
    • Inhibition of Alzheimer's amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo
    • H.S. Hong, S. Rana, L. Barrigan, A. Shi, Y. Zhang, F. Zhou, L.W. Jin, and D.H. Hua Inhibition of Alzheimer's amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo J. Neurochem. 108 4 2009 1097 1108
    • (2009) J. Neurochem. , vol.108 , Issue.4 , pp. 1097-1108
    • Hong, H.S.1    Rana, S.2    Barrigan, L.3    Shi, A.4    Zhang, Y.5    Zhou, F.6    Jin, L.W.7    Hua, D.H.8
  • 19
    • 58149479354 scopus 로고    scopus 로고
    • GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals
    • S. Hu, A.N. Begum, and M.R. Jones GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals Neurobiol. Dis. 33 2009 193 206
    • (2009) Neurobiol. Dis. , vol.33 , pp. 193-206
    • Hu, S.1    Begum, A.N.2    Jones, M.R.3
  • 20
    • 69249216362 scopus 로고    scopus 로고
    • Curcumin activates AMPK and suppresses gluconeogenci gene expression in hepatoma cells
    • T. Kim, J. Davis, A.J. Zhang, X. He, and S.T. Mathews Curcumin activates AMPK and suppresses gluconeogenci gene expression in hepatoma cells Biochem. Biophys. Res. Commun. 388 2 2009 377 382
    • (2009) Biochem. Biophys. Res. Commun. , vol.388 , Issue.2 , pp. 377-382
    • Kim, T.1    Davis, J.2    Zhang, A.J.3    He, X.4    Mathews, S.T.5
  • 21
    • 0029953780 scopus 로고    scopus 로고
    • Cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family
    • DOI 10.1016/S0092-8674(00)81267-2
    • E.T. Kipreos, L.E. Lander, J.P. Wing, W.W. He, and E.M. Hedgecock Cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family Cell 85 6 1996 829 839 (Pubitemid 26192134)
    • (1996) Cell , vol.85 , Issue.6 , pp. 829-839
    • Kipreos, E.T.1    Lander, L.E.2    Wing, J.P.3    He, W.W.4    Hedgecock, E.M.5
  • 22
    • 72849131596 scopus 로고    scopus 로고
    • Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression
    • J.J. Lai, K.P. Lai, K.H. Chuang, P. Chang, I.C. Yu, W.J. Lin, and C. Chang Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression J. Clin. Invest. 119 12 2009 3739 3751
    • (2009) J. Clin. Invest. , vol.119 , Issue.12 , pp. 3739-3751
    • Lai, J.J.1    Lai, K.P.2    Chuang, K.H.3    Chang, P.4    Yu, I.C.5    Lin, W.J.6    Chang, C.7
  • 24
    • 70549101361 scopus 로고    scopus 로고
    • Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress
    • J. Lin, S. Zheng, and A. Chen Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress Lab. Invest. 89 12 2009 1397 1409
    • (2009) Lab. Invest. , vol.89 , Issue.12 , pp. 1397-1409
    • Lin, J.1    Zheng, S.2    Chen, A.3
  • 25
    • 33644901007 scopus 로고    scopus 로고
    • Multiple biological activaties of curcumin: A short review
    • R.K. Maheshwari, A.K. Singh, J. Gaddipati, and R.C. Srimal Multiple biological activaties of curcumin: a short review Life Sci. 78 2006 2081 2087
    • (2006) Life Sci. , vol.78 , pp. 2081-2087
    • Maheshwari, R.K.1    Singh, A.K.2    Gaddipati, J.3    Srimal, R.C.4
  • 26
    • 79954628495 scopus 로고    scopus 로고
    • The Wnts signalling pathway
    • Miller The Wnts signalling pathway Genome Biol. 54 2002 205 215
    • (2002) Genome Biol. , vol.54 , pp. 205-215
    • Miller1
  • 27
    • 77950516262 scopus 로고    scopus 로고
    • Curcumin attenuates inflammatory response IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model
    • D.O. Moon, M.O. Kim, Y.H. Choi, Y.M. Park, and G.Y. Kim Curcumin attenuates inflammatory response IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model Int. Immunopharmacol. 10 5 2010 605 610
    • (2010) Int. Immunopharmacol. , vol.10 , Issue.5 , pp. 605-610
    • Moon, D.O.1    Kim, M.O.2    Choi, Y.H.3    Park, Y.M.4    Kim, G.Y.5
  • 29
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, β-Catenin, and Cadherin pathways
    • DOI 10.1126/science.1094291
    • W.J. Nelson, and R. Nusse Convergence of Wnt, beta-catenin, and cadherin pathways Science 303 5663 2004 1483 1487 (Pubitemid 38314410)
    • (2004) Science , vol.303 , Issue.5663 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 30
    • 19444362674 scopus 로고    scopus 로고
    • The inhibitory mechanism of curcumin and its derivative against β-catenin/Tcf signaling
    • DOI 10.1016/j.febslet.2005.04.013, PII S0014579305004734
    • C.H. Park, E.R. Hahm, and S. Park The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling FEBS Lett. 579 2005 2965 2971 (Pubitemid 40725275)
    • (2005) FEBS Letters , vol.579 , Issue.13 , pp. 2965-2971
    • Chi, H.P.1    Eun, R.H.2    Park, S.3    Kim, H.-K.4    Chul, H.Y.5
  • 31
    • 58149314221 scopus 로고    scopus 로고
    • Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models
    • H. Qing, G. He, and P.T. Ly Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models J. Exp. Med. 205 12 2008 2781 2789
    • (2008) J. Exp. Med. , vol.205 , Issue.12 , pp. 2781-2789
    • Qing, H.1    He, G.2    Ly, P.T.3
  • 32
    • 65549140727 scopus 로고    scopus 로고
    • Gamma-secretase heterogeneity in the Aph1 subunit: Relevance for Alzheimer's disease
    • L. Serneels, J. Van Biervliet, and K. Craessaerts Gamma-secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease Science 324 5927 2009 603 604
    • (2009) Science , vol.324 , Issue.5927 , pp. 603-604
    • Serneels, L.1    Van Biervliet, J.2    Craessaerts, K.3
  • 34
    • 77951711190 scopus 로고    scopus 로고
    • Curcumin protects rat myocardium against isoproterenol-induced ischemic injury: Attenuation of ventricular dysfunction through increased expression of Hsp27 along with strengthening antioxidant defense system
    • V. Tanwar, J. Sachdeva, M. Golechha, S. Kumari, and D.S. Arya Curcumin protects rat myocardium against isoproterenol-induced ischemic injury: attenuation of ventricular dysfunction through increased expression of Hsp27 along with strengthening antioxidant defense system J. Cardiovasc. Pharmacol. 55 4 2010 377 384
    • (2010) J. Cardiovasc. Pharmacol. , vol.55 , Issue.4 , pp. 377-384
    • Tanwar, V.1    Sachdeva, J.2    Golechha, M.3    Kumari, S.4    Arya, D.S.5
  • 35
    • 0034534014 scopus 로고    scopus 로고
    • GSK-3beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin
    • G. Tesco, and R.E. Tanzi GSK-3beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin Ann. N.Y. Acad. Sci. 920 2000 227 232
    • (2000) Ann. N.Y. Acad. Sci. , vol.920 , pp. 227-232
    • Tesco, G.1    Tanzi, R.E.2
  • 36
    • 48749133346 scopus 로고    scopus 로고
    • Wnt signaling in neuroprotection and stem cell differentiation
    • November 3
    • E.M. Toledo, M. Colombres, and N.C. Inestrosa Wnt signaling in neuroprotection and stem cell differentiation Prog. Neurobiol. 86 November (3) 2008 281 296
    • (2008) Prog. Neurobiol. , vol.86 , pp. 281-296
    • Toledo, E.M.1    Colombres, M.2    Inestrosa, N.C.3
  • 37
    • 33745853091 scopus 로고    scopus 로고
    • Presenilin-1 is an unprimed glycogen synthase kinase-3β substrate
    • DOI 10.1016/j.febslet.2006.06.035, PII S0014579306007423
    • C. Twomey, and J.V. McCarthy Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate FEBS Lett. 580 July (17) 2006 4015 4020 (Pubitemid 44037562)
    • (2006) FEBS Letters , vol.580 , Issue.17 , pp. 4015-4020
    • Twomey, C.1    McCarthy, J.V.2
  • 38
    • 15944378214 scopus 로고    scopus 로고
    • Beta-secretase. APP and Abeta in Alzheimer's disease
    • R. Vassar Beta-secretase. APP and Abeta in Alzheimer's disease Subcell. Biochem. 38 2005 79 103
    • (2005) Subcell. Biochem. , vol.38 , pp. 79-103
    • Vassar, R.1
  • 39
    • 51649110188 scopus 로고    scopus 로고
    • Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation
    • Q.G. Zhang, R. Wang, and M. Khan Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation J. Neurosci. 28 34 2008 8430 8441
    • (2008) J. Neurosci. , vol.28 , Issue.34 , pp. 8430-8441
    • Zhang, Q.G.1    Wang, R.2    Khan, M.3
  • 40
    • 68549101647 scopus 로고    scopus 로고
    • The regulation of curcumin on the amyloidogenic pathway of APP in Alzheimer's disease
    • H. Zhang, X. Zhang, and Y. Li The regulation of curcumin on the amyloidogenic pathway of APP in Alzheimer's disease Chin. Pharmacol. Bull. 25 3 2009 361 366
    • (2009) Chin. Pharmacol. Bull. , vol.25 , Issue.3 , pp. 361-366
    • Zhang, H.1    Zhang, X.2    Li, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.