17α-Estradiol arrests cell cycle progression at G2/M and induces apoptotic cell death in human acute leukemia Jurkat T cells

Toxicology and Applied Pharmacology

Volumn 231, Issue 3, 2008, Pages 401-412

  Jun, Do Youn ^a   Park, Hae Sun ^a   Kim, Jun Seok ^a   Kim, Jong Sik ^b   Park, Wan ^a   Song, Bang Ho ^c   Kim, Hee Sook ^c   Taub, Dennis ^d   Kim, Young Ho ^a  

^a Laboratory of Immunobiology   (South Korea)

^b Andong National University   (South Korea)

^c Kyungpook National University   (South Korea)

^d NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

17 Estradiol, G2 M arrest; Apoptosis; Bcl 2; Caspase cascade; Leukemia cells; Mitochondrial cytochrome c

Indexed keywords

17ALPHA ESTRADIOL; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8 INHIBITOR; CASPASE 9; CASPASE INHIBITOR; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYTOCHROME C; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ANTAGONIST; FAS ANTIBODY; FULVESTRANT; HYDROXYUREA; MIFEPRISTONE; NEUTRALIZING ANTIBODY ZB 4; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; THREONINE; TYROSINE; UNCLASSIFIED DRUG; CASPASE; ESTRADIOL;

ACUTE LEUKEMIA; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CELL STRAIN U937; CONTROLLED STUDY; CYTOTOXICITY; DEPHOSPHORYLATION; ESTROGEN ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NUCLEOTIDE SEQUENCE; PROTEIN PHOSPHORYLATION; CELL DEATH; CELL DIVISION; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; T CELL LEUKEMIA LYMPHOMA;

APOPTOSIS; CASPASES; CELL DEATH; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; G2 PHASE; HUMANS; JURKAT CELLS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; U937 CELLS;

EID: 51049099168     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.05.023     Document Type: Article

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