Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 11, 2010, Pages 3310-3313

  Kamal, Ahmed ^a   Vijaya Bharathi, E ^a   Janaki Ramaiah, M ^a   Surendranadha Reddy, J ^a   Dastagiri, D ^a   Viswanath, A ^a   Sultana, Farheen ^a   Pushpavalli, S N C V L ^a   Pal Bhadra, Manika ^a   Juvekar, Aarti ^b   Sen, Subrata ^b   Zingde, Surekha ^b  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b Research and Education in Cancer   (India)

Author keywords

Active caspase 3; Anthranilamide; Anticancer activity; Apoptosis; p53; Pyrrolobenzodiazepine

Indexed keywords

2 AMINOBENZAMIDE; CASPASE 3; PROTEIN P53; PYRROLO[2,1 C][1,4]BENZODIAZEPINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL LYSATE; DRUG INHIBITION; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; MELANOMA CELL; PROTEIN EXPRESSION;

ANTHRANILIC ACIDS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZODIAZEPINES; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; FLOW CYTOMETRY; HUMANS; PYRROLES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77953291575     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.037     Document Type: Article

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