The effect of C2-fluoro group on the biological activity of DC-81 and its dimers

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 10, 2004, Pages 2669-2672

  Kamal, Ahmed ^a   Reddy, P S M M ^a   Reddy, D Rajasekhar ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

C2 Fluoropyrrolobenzodiazepines; Cytotoxicity and DNA binding affinity

Indexed keywords

1,2,3,11A TETRAHYDRO 8 HYDROXY 7 METHOXY 5H PYRROLO[2,1 C][1,4]BENZODIAZEPIN 5 ONE; BENZODIAZEPINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DNA BINDING; DRUG EFFECT; DRUG SYNTHESIS; HUMAN; HUMAN CELL; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BENZODIAZEPINES; CELL LINE, TUMOR; CELL PROLIFERATION; DIMERIZATION; DNA; HUMANS; NUCLEIC ACID DENATURATION; ORGANOPHOSPHORUS COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 1942470112     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.063     Document Type: Article

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