Synthesis and structure-affinity relationships of novel dibenzylideneacetone derivatives as probes for ß-Amyloid Plaques

Journal of Medicinal Chemistry

Volumn 54, Issue 7, 2011, Pages 2225-2240

  Cui, Mengchao ^a,b   Ono, Masahiro ^a   Kimura, Hiroyuki ^a   Liu, Boli ^b   Saji, Hideo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b BEIJING NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLIDENEACETONE; DIBENZYLIDENEACETONE DERIVATIVE; RADIOACTIVE IODINE; RADIOLIGAND; UNCLASSIFIED DRUG;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; CONTROLLED STUDY; LIGAND BINDING; MOUSE; NEUROIMAGING; NONHUMAN; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION;

AGED; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; DRUG DESIGN; FEMALE; FLUORINE RADIOISOTOPES; HUMANS; LIGANDS; MALE; MICE; MOLECULAR PROBES; PENTANONES; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; POSITRON-EMISSION TOMOGRAPHY; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; RADIOCHEMISTRY; STRUCTURE-ACTIVITY RELATIONSHIP; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 79953794599     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm101404k     Document Type: Article

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