Novel chalcones as probes for in vivo imaging of β-amyloid plaques in Alzheimer's brains

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 21, 2007, Pages 6802-6809

  Ono, Masahiro ^a   Haratake, Mamoru ^a   Mori, Hiroshi ^b   Nakayama, Morio ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Amyloid; Alzheimer's disease; Imaging; PET; SPECT

Indexed keywords

1 (4 IODOPHENYL) 3 (4 METHOXYPHENYL)PROP 2 EN 1 ONE I 125; 1 (4 IODOPHENYL) 3 [4 (METHYLAMINO)PHENYL]PROP 2 EN 1 ONE I 125; 3 (4 AMINOPHENYL) 1 (4 IODOPHENYL)PROP 2 EN 1 ONE I 125; 3 (4 HYDROXYPHENYL) 1 (4 IODOPHENYL)PROP 2 EN 1 ONE I 125; 3 [4 (DIMETHYLAMINO)PHENYL] 1 (4 IODOPHENYL)PROP 2 EN 1 ONE I 125; AMYLOID BETA PROTEIN; CHALCONE DERIVATIVE; HYDROGEN PEROXIDE; TRIBUTYLTIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CHEMICAL REACTION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG STRUCTURE; DRUG SYNTHESIS; IN VIVO STUDY; MOUSE; NEUROIMAGING; NONHUMAN; RADIOACTIVITY; RADIOIODINATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CHALCONES; IODINE RADIOISOTOPES; MICE; MICE, TRANSGENIC; MOLECULAR PROBES; SENILE PLAQUES; SOLUTIONS;

MUS;

EID: 34548535442     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.07.052     Document Type: Article

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