Curcumin and dehydrozingerone derivatives: Synthesis, radiolabeling, and evaluation for β-amyloid plaque imaging

Journal of Medicinal Chemistry

Volumn 49, Issue 20, 2006, Pages 6111-6119

  Ryu, Eun Kyoung ^a   Choe, Yearn Seong ^a   Lee, Kyung Han ^a   Choi, Yong ^a   Kim, Byung Tae ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1 [4 (3 FLUOROPROPOXY) 3 METHOXYPHENYL] 5 HYDROXY 7 (4 HYDROXY 3 METHOXYPHENYL) 1,4,6 HEPTATRIEN 3 ONE; AMYLOID BETA PROTEIN; CURCUMIN; DEHYDROZINGERONE; FLUORINE 18; LIGAND; RADIOISOTOPE; RADIOLIGAND; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; BINDING AFFINITY; CONFERENCE PAPER; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG BINDING; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; EARLY DIAGNOSIS; INDIA; ISOTOPE LABELING; LIPOPHILICITY; MALE; MOUSE; NEUROFIBRILLARY TANGLE; NEUROIMAGING; NONHUMAN; PARTITION COEFFICIENT;

AMYLOID; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CURCUMIN; FLUORINE RADIOISOTOPES; GUAIACOL; ISOTOPE LABELING; LIGANDS; MALE; MICE; MICE, INBRED ICR; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; STYRENES; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 33749265462     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0607193     Document Type: Conference Paper

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