Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates

Journal of Medicinal Chemistry

Volumn 44, Issue 12, 2001, Pages 1905-1914

  Zhuang, Z P ^a   Kung, M P ^a   Hou, C ^a   Skovronsky, D M ^a   Gur, T L ^a   Plossl K ^a   Trojanowski, J Q ^a   Lee, V M Y ^a   Kung, H F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 IODO 2,5 BIS(3 HYDROXYCARBONYL 4 HYDROXY)STYRYLBENZENE; 1 IODO 2,5 BIS(3 HYDROXYCARBONYL 4 METHOXY)STYRYLBENZENE; 2 [4' (4'' METHYLPIPERAZIN 1 YL)PHENYL] 6 IODOBENZOTHIAZOLE; 2 [4' (DIMETHYLAMINO)PHENYL] 6 IODOBENZOTHIAZOLE; AMYLOID BETA PROTEIN; BENZOTHIAZOLE DERIVATIVE; IODINE 125; STYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING COMPETITION; BRAIN REGION; DOWN SYNDROME; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; DRUG SYNTHESIS; DRUG UPTAKE; HUMAN; HUMAN TISSUE; LIGAND BINDING; MOUSE; NONHUMAN; RADIOIODINATION; SENILE PLAQUE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; AUTORADIOGRAPHY; BENZENE DERIVATIVES; BLOOD-BRAIN BARRIER; BRAIN; DOWN SYNDROME; HUMANS; INDICATORS AND REAGENTS; IODINE RADIOISOTOPES; ISOTOPE LABELING; KINETICS; LIGANDS; MICE; PEPTIDE FRAGMENTS; STRUCTURE-ACTIVITY RELATIONSHIP; STYRENES; THIAZOLES; TISSUE DISTRIBUTION;

EID: 0035821603     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010045q     Document Type: Article

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