-
2
-
-
34547106018
-
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
-
Hideshima T., Mitsiades C., Tonon G., Richardson P.G., Anderson K.C. Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets. Nat Rev Cancer 2007, 7:585-598.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 585-598
-
-
Hideshima, T.1
Mitsiades, C.2
Tonon, G.3
Richardson, P.G.4
Anderson, K.C.5
-
4
-
-
67249086097
-
Infections in patients with multiple myeloma
-
Nucci M., Anaissie E. Infections in patients with multiple myeloma. Semin Hematol 2009, 46(3):277-288.
-
(2009)
Semin Hematol
, vol.46
, Issue.3
, pp. 277-288
-
-
Nucci, M.1
Anaissie, E.2
-
5
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira Sh, Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
6
-
-
31344453943
-
Immune suppression in cancer: effects on immune cells, mechanisms and future therapeutic intervention
-
Whiteside T.L. Immune suppression in cancer: effects on immune cells, mechanisms and future therapeutic intervention. Semin Cancer Biol 2006, 16:3-15.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 3-15
-
-
Whiteside, T.L.1
-
7
-
-
37849035627
-
TLR signaling by tumor and immune cells: a double-edged sword
-
Huang B., Zhao J., Unkeless J.C., Feng Z.H., Xiong H. TLR signaling by tumor and immune cells: a double-edged sword. Oncogene 2008, 27:218-224.
-
(2008)
Oncogene
, vol.27
, pp. 218-224
-
-
Huang, B.1
Zhao, J.2
Unkeless, J.C.3
Feng, Z.H.4
Xiong, H.5
-
9
-
-
20444432334
-
Toll-like receptors on tumor cells facilitates evasion of immune surveillance
-
Huang B., Zhao J., Li H., et al. Toll-like receptors on tumor cells facilitates evasion of immune surveillance. Cancer Res 2005, 65:5009-5014.
-
(2005)
Cancer Res
, vol.65
, pp. 5009-5014
-
-
Huang, B.1
Zhao, J.2
Li, H.3
-
10
-
-
34347400169
-
Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-γ and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway
-
Liu J., Hamrouni A., Wolowiec D., et al. Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-γ and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway. Blood 2007, 110:296-304.
-
(2007)
Blood
, vol.110
, pp. 296-304
-
-
Liu, J.1
Hamrouni, A.2
Wolowiec, D.3
-
11
-
-
33744465220
-
Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptors
-
Jego G., Bataillie R., Geffroy-Leuseau A., Descamps G., Pellat-Deceunynck C. Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptors. Leukemia 2006, 20:1130-1137.
-
(2006)
Leukemia
, vol.20
, pp. 1130-1137
-
-
Jego, G.1
Bataillie, R.2
Geffroy-Leuseau, A.3
Descamps, G.4
Pellat-Deceunynck, C.5
-
12
-
-
33744459726
-
Toll-like receptors mediate proliferation and survival of multiple myeloma cells
-
Bohnhorst J., Rasmussen T., Moen S.H., et al. Toll-like receptors mediate proliferation and survival of multiple myeloma cells. Leukemia 2006, 20:1138-1144.
-
(2006)
Leukemia
, vol.20
, pp. 1138-1144
-
-
Bohnhorst, J.1
Rasmussen, T.2
Moen, S.H.3
-
13
-
-
78149361152
-
Toll-like receptors: expression and involvement in multiple myeloma
-
Chiron D., Jego G., Pellat-Deuceunynck C. Toll-like receptors: expression and involvement in multiple myeloma. Leukemia Res 2010, 10.1016/j.leukres.2010.06.002.
-
(2010)
Leukemia Res
-
-
Chiron, D.1
Jego, G.2
Pellat-Deuceunynck, C.3
-
14
-
-
77955804238
-
Expression and function of toll-like receptors in multiple myeloma patients: Toll-like receptor ligands promote multiple myeloma cell growth and survival via activation of nuclear factor-κB
-
Xu Y., Zhao Y., Huang H., et al. Expression and function of toll-like receptors in multiple myeloma patients: Toll-like receptor ligands promote multiple myeloma cell growth and survival via activation of nuclear factor-κB. Brit J Haematol 2010, 150:543-553.
-
(2010)
Brit J Haematol
, vol.150
, pp. 543-553
-
-
Xu, Y.1
Zhao, Y.2
Huang, H.3
-
15
-
-
77955475327
-
Crosstalk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells
-
Li H., Hong S., Qian J., Zheng Y., Yang J., Yi Q. Crosstalk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells. Blood 2010, 116:210-217.
-
(2010)
Blood
, vol.116
, pp. 210-217
-
-
Li, H.1
Hong, S.2
Qian, J.3
Zheng, Y.4
Yang, J.5
Yi, Q.6
-
16
-
-
45149127782
-
Osteoimmunology: interactions of the bone and immune system
-
Lorenzo J., Horowitz M., Choi Y. Osteoimmunology: interactions of the bone and immune system. Endocr Rev 2008, 29(4):403-440.
-
(2008)
Endocr Rev
, vol.29
, Issue.4
, pp. 403-440
-
-
Lorenzo, J.1
Horowitz, M.2
Choi, Y.3
-
17
-
-
0035253370
-
Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa in B activation
-
Faure E., Thomas L., Xu H., Medvedev A.E., Equils O., Arditi M. Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa in B activation. J Immunol 2001, 66:2018-2024.
-
(2001)
J Immunol
, vol.66
, pp. 2018-2024
-
-
Faure, E.1
Thomas, L.2
Xu, H.3
Medvedev, A.E.4
Equils, O.5
Arditi, M.6
-
18
-
-
3142724031
-
Toll-like receptor signaling
-
Akiras Sh., Takeda K. Toll-like receptor signaling. Nat Rev Immunol 2004, 4:499-511.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akiras, S.1
Takeda, K.2
-
19
-
-
36049033394
-
Signalling to NFκB by Toll-like receptors
-
Kawai T., Akiro Sh. Signalling to NFκB by Toll-like receptors. Trends Mol Med 2007, 13(11):460-469.
-
(2007)
Trends Mol Med
, vol.13
, Issue.11
, pp. 460-469
-
-
Kawai, T.1
Akiro, S.2
-
20
-
-
33646147362
-
Toll-like receptor function and signalling
-
Kaisho T., Akiro Sh. Toll-like receptor function and signalling. J Allergy Clin Immunol 2006, 117:979-987.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 979-987
-
-
Kaisho, T.1
Akiro, S.2
-
21
-
-
0742324860
-
TLR signalling pathways
-
Takeda K., Akiro Sh. TLR signalling pathways. Semin Immunol 2004, 16:3-9.
-
(2004)
Semin Immunol
, vol.16
, pp. 3-9
-
-
Takeda, K.1
Akiro, S.2
-
22
-
-
37549058765
-
Toll-like receptors' two-edged sword: when immunity meets apoptosis
-
Salaun B., Romero P., Lebecque S. Toll-like receptors' two-edged sword: when immunity meets apoptosis. Eur J Immunol 2007, 37:3311-3318.
-
(2007)
Eur J Immunol
, vol.37
, pp. 3311-3318
-
-
Salaun, B.1
Romero, P.2
Lebecque, S.3
-
23
-
-
5444254408
-
Toll-like receptors in the pathogenesis of human disease
-
Cook D.N., Pisetsky D.S., Schwartz D.A. Toll-like receptors in the pathogenesis of human disease. Nat Immunol 2004, 5(10):975-979.
-
(2004)
Nat Immunol
, vol.5
, Issue.10
, pp. 975-979
-
-
Cook, D.N.1
Pisetsky, D.S.2
Schwartz, D.A.3
-
24
-
-
33846967820
-
Gene polymorphisms in Toll-like receptors, interleukin-10 and interleukin-10 receptor alpha and lymphoma risk
-
Nieters A., Beckmann L., Deeg E., Becker N. Gene polymorphisms in Toll-like receptors, interleukin-10 and interleukin-10 receptor alpha and lymphoma risk. Genes Immun 2006, 7(8):615-624.
-
(2006)
Genes Immun
, vol.7
, Issue.8
, pp. 615-624
-
-
Nieters, A.1
Beckmann, L.2
Deeg, E.3
Becker, N.4
-
25
-
-
0037057521
-
Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion
-
Harmey J.H., Bucana C.D., Lu W., et al. Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. Int J Cancer 2002, 101(5):415-422.
-
(2002)
Int J Cancer
, vol.101
, Issue.5
, pp. 415-422
-
-
Harmey, J.H.1
Bucana, C.D.2
Lu, W.3
-
26
-
-
35948972112
-
Activation of Toll-like receptor 4 on tumor cells in vitro inhibits subsequent tumor growth in vivo
-
Andreani V., Gatti G., Simonella L., Rivero V., Maccioni M. Activation of Toll-like receptor 4 on tumor cells in vitro inhibits subsequent tumor growth in vivo. Cancer Res 2007, 67:10519-10527.
-
(2007)
Cancer Res
, vol.67
, pp. 10519-10527
-
-
Andreani, V.1
Gatti, G.2
Simonella, L.3
Rivero, V.4
Maccioni, M.5
-
27
-
-
33645727988
-
TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer
-
Kelly M.G., Alvero A.B., Chen R., et al. TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer. Cancer Res 2006, 66:3859-3868.
-
(2006)
Cancer Res
, vol.66
, pp. 3859-3868
-
-
Kelly, M.G.1
Alvero, A.B.2
Chen, R.3
-
28
-
-
0035992782
-
Antitumor Mechanisms of oligodeoxynucleotides with CpG and polyG motifs in murine prostate cancer cells: decrease of NF-kB and AP-1 binding activities and induction of apoptosis
-
Shen W., Waldschemidt M., Zhao X., Ratilff T., Krieg A.M. Antitumor Mechanisms of oligodeoxynucleotides with CpG and polyG motifs in murine prostate cancer cells: decrease of NF-kB and AP-1 binding activities and induction of apoptosis. Antisense Nucl Drug Dev 2002, 12:155-164.
-
(2002)
Antisense Nucl Drug Dev
, vol.12
, pp. 155-164
-
-
Shen, W.1
Waldschemidt, M.2
Zhao, X.3
Ratilff, T.4
Krieg, A.M.5
-
29
-
-
39449118809
-
Poly I:C enhances cycloheximide-induced apoptosis of tumor cells through TLR3 pathway
-
Jiang Q., Wei H., Tian Zh. Poly I:C enhances cycloheximide-induced apoptosis of tumor cells through TLR3 pathway. BMC Cancer 2008, 8:12.
-
(2008)
BMC Cancer
, vol.8
, pp. 12
-
-
Jiang, Q.1
Wei, H.2
Tian, Z.3
-
30
-
-
33746882098
-
Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity
-
Merrell M.A., Ilvesaro J.M., Lehtonen N., et al. Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity. Mol Cancer Res 2006, 4:437-447.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 437-447
-
-
Merrell, M.A.1
Ilvesaro, J.M.2
Lehtonen, N.3
-
31
-
-
25444470242
-
Human lung cancer cells express functionally active Toll-like receptor 9
-
Droemann D., Albrecht D., Gerdes J., et al. Human lung cancer cells express functionally active Toll-like receptor 9. Resp Res 2005, 6:1-10.
-
(2005)
Resp Res
, vol.6
, pp. 1-10
-
-
Droemann, D.1
Albrecht, D.2
Gerdes, J.3
-
32
-
-
0041743207
-
The Toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells
-
Bourke E., Bosisio D., Golay J., Polentarutti N., Mantovani A. The Toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood 2003, 102:956-963.
-
(2003)
Blood
, vol.102
, pp. 956-963
-
-
Bourke, E.1
Bosisio, D.2
Golay, J.3
Polentarutti, N.4
Mantovani, A.5
-
33
-
-
55249107642
-
Toll-like receptors: lessons to learn from normal and malignant B cells
-
Chiron D., Bekeredjian-Ding I., Pellat-Deceunynck C., Bataille R., Jego G. Toll-like receptors: lessons to learn from normal and malignant B cells. Blood 2008, 112:2205-2213.
-
(2008)
Blood
, vol.112
, pp. 2205-2213
-
-
Chiron, D.1
Bekeredjian-Ding, I.2
Pellat-Deceunynck, C.3
Bataille, R.4
Jego, G.5
-
34
-
-
0038142387
-
A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naïve B cells and constitutive expression in memory B cells
-
Bernasconi N.L., Onai N., Lanzavecchia A. A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naïve B cells and constitutive expression in memory B cells. Blood 2003, 101:4500-4504.
-
(2003)
Blood
, vol.101
, pp. 4500-4504
-
-
Bernasconi, N.L.1
Onai, N.2
Lanzavecchia, A.3
-
35
-
-
0037073930
-
Maintenance of serological memory by polyclonal activation of human memory B cells
-
Bernasconi N.L., Onai N., Lanzavecchia A. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 2002, 298:2199-2202.
-
(2002)
Science
, vol.298
, pp. 2199-2202
-
-
Bernasconi, N.L.1
Onai, N.2
Lanzavecchia, A.3
-
36
-
-
70449371316
-
Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production
-
Dorner M., Brandt S., Tinguely M., et al. Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production. Immunology 2009, 128:573-579.
-
(2009)
Immunology
, vol.128
, pp. 573-579
-
-
Dorner, M.1
Brandt, S.2
Tinguely, M.3
-
37
-
-
45849130522
-
Toll-like receptors expressed in tumour cells: targets for therapy
-
Yu L., Chen Sh. Toll-like receptors expressed in tumour cells: targets for therapy. Cancer Immunol Immunother 2008, 57:1271-1278.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1271-1278
-
-
Yu, L.1
Chen, S.2
-
38
-
-
36348953188
-
Expression of functional Toll-like receptors by B-chronic lymphocytic leukemia cells
-
Grandjenette C., Kennel A., Faure G.C., Bene M.C., Feugier P. Expression of functional Toll-like receptors by B-chronic lymphocytic leukemia cells. Haematologica 2007, 92:1279-1281.
-
(2007)
Haematologica
, vol.92
, pp. 1279-1281
-
-
Grandjenette, C.1
Kennel, A.2
Faure, G.C.3
Bene, M.C.4
Feugier, P.5
-
39
-
-
33644850641
-
Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphocytic leukemia
-
Corthals S.L., Wynne K., She K., et al. Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphocytic leukemia. Brit J Haematol 2005, 132:452-458.
-
(2005)
Brit J Haematol
, vol.132
, pp. 452-458
-
-
Corthals, S.L.1
Wynne, K.2
She, K.3
-
40
-
-
20044371011
-
B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides
-
Jahrsdorfer B., Muhlenhoff L., Blackwell S.E., et al. B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides. Clin Cancer Res 2005, 11:1490-1499.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1490-1499
-
-
Jahrsdorfer, B.1
Muhlenhoff, L.2
Blackwell, S.E.3
-
41
-
-
68549103458
-
A threshold level of TLR9 mRNA predicts cellular responsiveness to CpG-ODN in haematological and non-haematological tumour cell lines
-
Assaf A., Esteves H., Curnow S.J., Browning M.J. A threshold level of TLR9 mRNA predicts cellular responsiveness to CpG-ODN in haematological and non-haematological tumour cell lines. Cell Immunol 2009, 259(1):90-99.
-
(2009)
Cell Immunol
, vol.259
, Issue.1
, pp. 90-99
-
-
Assaf, A.1
Esteves, H.2
Curnow, S.J.3
Browning, M.J.4
-
42
-
-
0027133422
-
Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion
-
Uchiyama H., Barut B.A., Mohrbacher A.F., Chauhan D., Anderson K.C. Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion. Blood 1993, 82:3712-3720.
-
(1993)
Blood
, vol.82
, pp. 3712-3720
-
-
Uchiyama, H.1
Barut, B.A.2
Mohrbacher, A.F.3
Chauhan, D.4
Anderson, K.C.5
-
43
-
-
0028101292
-
Primary tumor cells of myeloma patients induce interleukin-6 secretion in long-term bone marrow cultures
-
Lokhorst H.M., Lamme T., de Smet K.S., de Weger R.A., van Oers R., Bloem A.C. Primary tumor cells of myeloma patients induce interleukin-6 secretion in long-term bone marrow cultures. Blood 1994, 84:2269-2277.
-
(1994)
Blood
, vol.84
, pp. 2269-2277
-
-
Lokhorst, H.M.1
Lamme, T.2
de Smet, K.S.3
de Weger, R.A.4
van Oers, R.5
Bloem, A.C.6
-
44
-
-
0035195019
-
Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications
-
Gupta D., Treon S.P., Shima Y., et al. Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications. Leukemia 2001, 15:1950-1961.
-
(2001)
Leukemia
, vol.15
, pp. 1950-1961
-
-
Gupta, D.1
Treon, S.P.2
Shima, Y.3
-
45
-
-
0038446643
-
Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma
-
Bisping G., Leo R., Wenning D., et al. Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma. Blood 2003, 101:2775-2783.
-
(2003)
Blood
, vol.101
, pp. 2775-2783
-
-
Bisping, G.1
Leo, R.2
Wenning, D.3
-
46
-
-
0038369758
-
Cell adhesion-mediated drug resistance (CAM-DR) is associated with activation of NF-κB (RelB/p50) in myeloma cells
-
Landowski T.H., Olashaw N.E., Agrawal D., Dalton W.S. Cell adhesion-mediated drug resistance (CAM-DR) is associated with activation of NF-κB (RelB/p50) in myeloma cells. Oncogene 2003, 22:2417-2421.
-
(2003)
Oncogene
, vol.22
, pp. 2417-2421
-
-
Landowski, T.H.1
Olashaw, N.E.2
Agrawal, D.3
Dalton, W.S.4
-
47
-
-
34547660308
-
Promiscuous mutations activate the non-canonical NF-kB pathway in multiple myeloma
-
Keats J.J., Fonseca R., Chesi M., et al. Promiscuous mutations activate the non-canonical NF-kB pathway in multiple myeloma. Cancer Cell 2007, 12:131-144.
-
(2007)
Cancer Cell
, vol.12
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
-
48
-
-
77951719556
-
Classical and/or alternative NFκB pathway activation in multiple myeloma
-
Demchenko Y.N., Glebov O.K., Zingone A., Keats J.J., Bergsagel P.L., Kuehl W.M. Classical and/or alternative NFκB pathway activation in multiple myeloma. Blood 2010, 115(17):3541-3552.
-
(2010)
Blood
, vol.115
, Issue.17
, pp. 3541-3552
-
-
Demchenko, Y.N.1
Glebov, O.K.2
Zingone, A.3
Keats, J.J.4
Bergsagel, P.L.5
Kuehl, W.M.6
-
49
-
-
49249088078
-
Comparison of human B cell activation by TLR7 and TLR9 agonists
-
Hanten J.A., Vasilakos J.P., Riter Ch.L., et al. Comparison of human B cell activation by TLR7 and TLR9 agonists. BMC Immunol 2008, 9:39.
-
(2008)
BMC Immunol
, vol.9
, pp. 39
-
-
Hanten, J.A.1
Vasilakos, J.P.2
Riter, C.3
-
50
-
-
27844541797
-
Control of B cell responses by Toll-like receptors
-
Pasare Ch, Medzhitov R. Control of B cell responses by Toll-like receptors. Nature 2005, 438:364-368.
-
(2005)
Nature
, vol.438
, pp. 364-368
-
-
Pasare, C.1
Medzhitov, R.2
-
51
-
-
45449094567
-
Activation-dependent induction of Blimp-1
-
Calame K. Activation-dependent induction of Blimp-1. Curr Opin Immunol 2008, 20:259-264.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 259-264
-
-
Calame, K.1
-
52
-
-
14944362858
-
Regulation of plasma cell development
-
Shapiro-Shelef M., Calame K. Regulation of plasma cell development. Nature 2005, 5:230-242.
-
(2005)
Nature
, vol.5
, pp. 230-242
-
-
Shapiro-Shelef, M.1
Calame, K.2
-
53
-
-
28544444025
-
Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow
-
Shapiro-Shelef M., Lin K.I., Savitsky D., Liao J., Calame K. Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow. J Exp Med 2005, 202:1471-1476.
-
(2005)
J Exp Med
, vol.202
, pp. 1471-1476
-
-
Shapiro-Shelef, M.1
Lin, K.I.2
Savitsky, D.3
Liao, J.4
Calame, K.5
-
54
-
-
34247154497
-
MyD88 is required for the formation of long-term humoral immunity to virus infection
-
Guay H.M., Andreyeva T.A., Garcea R.L., Welsh R.M., Szomolanyi-Tsuda E. MyD88 is required for the formation of long-term humoral immunity to virus infection. J Immunol 2007, 178:5124-5131.
-
(2007)
J Immunol
, vol.178
, pp. 5124-5131
-
-
Guay, H.M.1
Andreyeva, T.A.2
Garcea, R.L.3
Welsh, R.M.4
Szomolanyi-Tsuda, E.5
-
55
-
-
65649123377
-
Toll-like receptors and their role in hematologic malignancies
-
Wolska A., Lech-Maranda E., Robak T. Toll-like receptors and their role in hematologic malignancies. Curr Mol Med 2009, 9(3):324-335.
-
(2009)
Curr Mol Med
, vol.9
, Issue.3
, pp. 324-335
-
-
Wolska, A.1
Lech-Maranda, E.2
Robak, T.3
-
56
-
-
0347626018
-
Interleukin-18 in multiple myeloma patients: serum levels in relation to response to treatment and survival
-
Alexandrakis M.G., Passam F.H., Sfiridaki K., et al. Interleukin-18 in multiple myeloma patients: serum levels in relation to response to treatment and survival. Leukemia Res 2004, 28:259-266.
-
(2004)
Leukemia Res
, vol.28
, pp. 259-266
-
-
Alexandrakis, M.G.1
Passam, F.H.2
Sfiridaki, K.3
-
57
-
-
0037484922
-
Growth mechanism of human myeloma cells by interleukin-6
-
Kawano M.M., Ishikawa H., Tsuyama N., et al. Growth mechanism of human myeloma cells by interleukin-6. Int J Hematol 2002, 76 Supplement I.
-
(2002)
Int J Hematol
, vol.76
, Issue.SUPPL. I
-
-
Kawano, M.M.1
Ishikawa, H.2
Tsuyama, N.3
-
58
-
-
0032711250
-
IL-6 up-regulates Mcl-1 in human myeloma cells through JAK/STAT rather than Ras/MAP kinase pathway
-
Puthier D., Bataille R., Amiot M. IL-6 up-regulates Mcl-1 in human myeloma cells through JAK/STAT rather than Ras/MAP kinase pathway. Eur J Immunol 1999, 29:3945-3950.
-
(1999)
Eur J Immunol
, vol.29
, pp. 3945-3950
-
-
Puthier, D.1
Bataille, R.2
Amiot, M.3
-
59
-
-
0027960892
-
Interleukin-6 prevents dexamethasone-induced myeloma cell death
-
Hardin J., MacLeod S., Grigorieva L., et al. Interleukin-6 prevents dexamethasone-induced myeloma cell death. Blood 1994, 84(9):3063-3070.
-
(1994)
Blood
, vol.84
, Issue.9
, pp. 3063-3070
-
-
Hardin, J.1
MacLeod, S.2
Grigorieva, L.3
-
60
-
-
0031029911
-
Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells
-
Chauhan Dh., Kharbanda S., Ogata A., et al. Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells. Blood 1997, 89(1):227-234.
-
(1997)
Blood
, vol.89
, Issue.1
, pp. 227-234
-
-
Chauhan, D.1
Kharbanda, S.2
Ogata, A.3
-
61
-
-
0035863942
-
Autocrine interleukin-6 production and highly malignant multiple myeloma: relation with resistance to drug-induced apoptosis
-
Frassanito M.A., Cusmai A., Iodice G., Dammacco F. Autocrine interleukin-6 production and highly malignant multiple myeloma: relation with resistance to drug-induced apoptosis. Blood 2001, 97:483-489.
-
(2001)
Blood
, vol.97
, pp. 483-489
-
-
Frassanito, M.A.1
Cusmai, A.2
Iodice, G.3
Dammacco, F.4
-
62
-
-
0031911838
-
Interleukin-6 in multiple myeloma and related plasma cell dyscrasias
-
Treon S.P., Anderson K.C. Interleukin-6 in multiple myeloma and related plasma cell dyscrasias. Curr Opin Hematol 1998, 5:42-48.
-
(1998)
Curr Opin Hematol
, vol.5
, pp. 42-48
-
-
Treon, S.P.1
Anderson, K.C.2
-
63
-
-
77951224783
-
Lymphoma and myeloma cell resistance to cytotoxic agents and ionizing radiations is not affected by exposure to anti-IL-6 antibody
-
Gougelet A.L., Mansuy A., Blay J.Y., Alberti L., Vermot-Desroches C. Lymphoma and myeloma cell resistance to cytotoxic agents and ionizing radiations is not affected by exposure to anti-IL-6 antibody. PLoS ONE 2009, 4(11):e8026.
-
(2009)
PLoS ONE
, vol.4
, Issue.11
-
-
Gougelet, A.L.1
Mansuy, A.2
Blay, J.Y.3
Alberti, L.4
Vermot-Desroches, C.5
-
64
-
-
0030742741
-
The effect on growth and survival of IL-6 can be dissociated in the U-266-1970/U-266-1984 and HL407E/HL407L human multiple myeloma cell lines
-
Spets H., Jernberg-Wiklund H., Sambade C., Söderberg O., Nilsson K. The effect on growth and survival of IL-6 can be dissociated in the U-266-1970/U-266-1984 and HL407E/HL407L human multiple myeloma cell lines. Br J Haematol 1997, 98:126-133.
-
(1997)
Br J Haematol
, vol.98
, pp. 126-133
-
-
Spets, H.1
Jernberg-Wiklund, H.2
Sambade, C.3
Söderberg, O.4
Nilsson, K.5
-
65
-
-
0030292721
-
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of Stat-3 in anti-apoptosis
-
Fukada T., Hibi M., Yamanaka Y., et al. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of Stat-3 in anti-apoptosis. Immunity 1996, 5:449-460.
-
(1996)
Immunity
, vol.5
, pp. 449-460
-
-
Fukada, T.1
Hibi, M.2
Yamanaka, Y.3
-
66
-
-
0030948787
-
Blockade of mitogen-activated protein kinase cascade signalling in interleukin 6-independent multiple myeloma cells
-
Ogata A., Chauhan Dh, Urashima M., Teoh G., Treon S.P., Anderson K.C. Blockade of mitogen-activated protein kinase cascade signalling in interleukin 6-independent multiple myeloma cells. Clin Cancer Res 1997, 3:1017-1022.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 1017-1022
-
-
Ogata, A.1
Chauhan, D.2
Urashima, M.3
Teoh, G.4
Treon, S.P.5
Anderson, K.C.6
-
67
-
-
0031225483
-
IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade
-
Ogata A., Chauhan Dh, Teoh G., et al. IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade. J Immunol 1997, 159(221):2-2221.
-
(1997)
J Immunol
, vol.159
, Issue.221
, pp. 2-2221
-
-
Ogata, A.1
Chauhan, D.2
Teoh, G.3
-
68
-
-
1942454400
-
Bacterial lipopolysacharide induces proliferation of IL-6-dependent plasmacytoma cells by MAPK pathway activation
-
Iankov I., Atanasova G., Praskova M., et al. Bacterial lipopolysacharide induces proliferation of IL-6-dependent plasmacytoma cells by MAPK pathway activation. Immunobiology 2004, 208:445-454.
-
(2004)
Immunobiology
, vol.208
, pp. 445-454
-
-
Iankov, I.1
Atanasova, G.2
Praskova, M.3
-
69
-
-
0034353524
-
The interleukin-6 receptor alpha-chain (CD126) is expressed by neoplastic but not normal plasma cells
-
Rawstron A.C., Fenton J.A.L., Ashcroft J., et al. The interleukin-6 receptor alpha-chain (CD126) is expressed by neoplastic but not normal plasma cells. Blood 2000, 96:3880-3886.
-
(2000)
Blood
, vol.96
, pp. 3880-3886
-
-
Rawstron, A.C.1
Fenton, J.A.L.2
Ashcroft, J.3
-
70
-
-
64249114110
-
TLR3 ligand induces NF-κB activation and various fates of multiple myeloma cells depending on IFN-α production
-
Chiron D., Pellat-Deceunynck C., Amiot M., Bataille R., Jego G. TLR3 ligand induces NF-κB activation and various fates of multiple myeloma cells depending on IFN-α production. J Immunol 2009, 182:4471-4478.
-
(2009)
J Immunol
, vol.182
, pp. 4471-4478
-
-
Chiron, D.1
Pellat-Deceunynck, C.2
Amiot, M.3
Bataille, R.4
Jego, G.5
-
71
-
-
33646581238
-
Classical and alternative NF-kB activation pathways and their roles in lymphoid malignancies
-
Nishikori M. Classical and alternative NF-kB activation pathways and their roles in lymphoid malignancies. J Clin Exp Hematopathol 2005, 45:15-24.
-
(2005)
J Clin Exp Hematopathol
, vol.45
, pp. 15-24
-
-
Nishikori, M.1
-
72
-
-
0038217997
-
Anti-tumour activity of interferon-alpha in multiple myeloma: role of interleukin 6 and tumor cell differentiation
-
Matsui W., Ann Huff C., Vala M., Barber J., Smith B.D., Jones R.J. Anti-tumour activity of interferon-alpha in multiple myeloma: role of interleukin 6 and tumor cell differentiation. Brit J Haematol 2003, 121:251-258.
-
(2003)
Brit J Haematol
, vol.121
, pp. 251-258
-
-
Matsui, W.1
Ann Huff, C.2
Vala, M.3
Barber, J.4
Smith, B.D.5
Jones, R.J.6
-
73
-
-
0034672243
-
Interferon alpha down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells
-
Xu D., Erickson S., Szeps M.L., et al. Interferon alpha down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells. Blood 2000, 96:4313-4318.
-
(2000)
Blood
, vol.96
, pp. 4313-4318
-
-
Xu, D.1
Erickson, S.2
Szeps, M.L.3
-
74
-
-
0033045756
-
Interferon-a protects myeloma cell lines from dexamethasone-induced apoptosis
-
Liu P., Oken M., Ness B.V. Interferon-a protects myeloma cell lines from dexamethasone-induced apoptosis. Leukemia 1999, 13:473-480.
-
(1999)
Leukemia
, vol.13
, pp. 473-480
-
-
Liu, P.1
Oken, M.2
Ness, B.V.3
-
75
-
-
77952214698
-
Anti-proliferative properties of type I and type II interferon
-
Bekisz J., Baron S., Balinsky C., Morrow A., Zoon K.C. Anti-proliferative properties of type I and type II interferon. Pharmaceuticals 2010, 3:994-1015.
-
(2010)
Pharmaceuticals
, vol.3
, pp. 994-1015
-
-
Bekisz, J.1
Baron, S.2
Balinsky, C.3
Morrow, A.4
Zoon, K.C.5
-
76
-
-
0036659945
-
Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6
-
Ratta M., Fagnoni F., Curti A., et al. Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6. Blood 2002, 100:230-237.
-
(2002)
Blood
, vol.100
, pp. 230-237
-
-
Ratta, M.1
Fagnoni, F.2
Curti, A.3
-
77
-
-
43749089136
-
NK resistance of tumor cells from multiple myeloma and chronic lymphocytic leukemia patients: implication of HLA-G
-
Maki G., Hayes G.M., Naji A., et al. NK resistance of tumor cells from multiple myeloma and chronic lymphocytic leukemia patients: implication of HLA-G. Leukemia 2008, 22:998-1006.
-
(2008)
Leukemia
, vol.22
, pp. 998-1006
-
-
Maki, G.1
Hayes, G.M.2
Naji, A.3
-
78
-
-
30144444962
-
Dysfunctional T regulatory cells in multiple myeloma
-
Prabhala R.H., Neri P., Bae J.E., et al. Dysfunctional T regulatory cells in multiple myeloma. Blood 2006, 107:301-304.
-
(2006)
Blood
, vol.107
, pp. 301-304
-
-
Prabhala, R.H.1
Neri, P.2
Bae, J.E.3
-
79
-
-
0030884240
-
Myeloma bone marrow plasma cells: evidence for their capacity as antigen-presenting cells
-
Yi Q., Dabadghao S., Sterborg A.Ö., Bergenbrant S., Holm G. Myeloma bone marrow plasma cells: evidence for their capacity as antigen-presenting cells. Blood 1997, 90(5):1960-1967.
-
(1997)
Blood
, vol.90
, Issue.5
, pp. 1960-1967
-
-
Yi, Q.1
Dabadghao, S.2
Sterborg, A.Ö.3
Bergenbrant, S.4
Holm, G.5
-
80
-
-
70349577375
-
Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target
-
Chauhan Dh., Singh A.V., Brahmandam M., et al. Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target. Cancer Cell 2009, 16:309-323.
-
(2009)
Cancer Cell
, vol.16
, pp. 309-323
-
-
Chauhan, D.1
Singh, A.V.2
Brahmandam, M.3
-
81
-
-
33745779502
-
The molecular classification of multiple myeloma
-
Zhan F., Huang Y., Colla S., et al. The molecular classification of multiple myeloma. Blood 2006, 108(6):2020-2028.
-
(2006)
Blood
, vol.108
, Issue.6
, pp. 2020-2028
-
-
Zhan, F.1
Huang, Y.2
Colla, S.3
-
82
-
-
42649114059
-
The IRF family transcription factors in immunity and oncogenesis
-
Tamura T., Yanai H., Savitsky D., Taniguchi T. The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol 2008, 26:535-584.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 535-584
-
-
Tamura, T.1
Yanai, H.2
Savitsky, D.3
Taniguchi, T.4
-
83
-
-
77449101221
-
Regulation of immunity and oncogenesis by the IRF transcription factor family
-
Savitsky D., Tamura T., Yanai H., Taniguchi T. Regulation of immunity and oncogenesis by the IRF transcription factor family. Cancer Immunol Immunother 2010, 59:489-510.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 489-510
-
-
Savitsky, D.1
Tamura, T.2
Yanai, H.3
Taniguchi, T.4
-
84
-
-
77950554962
-
Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration
-
Grote K., Schuett H., Salguero G., et al. Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration. Blood 2010, 115:2543-2552.
-
(2010)
Blood
, vol.115
, pp. 2543-2552
-
-
Grote, K.1
Schuett, H.2
Salguero, G.3
-
85
-
-
0037057521
-
Lipopolysaccaride-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion
-
Harmey J.H., Bucana C.D., Lu W., et al. Lipopolysaccaride-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. Int J Cancer 2002, 101:415-422.
-
(2002)
Int J Cancer
, vol.101
, pp. 415-422
-
-
Harmey, J.H.1
Bucana, C.D.2
Lu, W.3
-
86
-
-
41649115210
-
Sequence-and target-independent angiogenesis suppression by siRNA via TLR3
-
Kleinman M.E., Yamada K., Takeda A., et al. Sequence-and target-independent angiogenesis suppression by siRNA via TLR3. Nature 2008, 452(3):591-598.
-
(2008)
Nature
, vol.452
, Issue.3
, pp. 591-598
-
-
Kleinman, M.E.1
Yamada, K.2
Takeda, A.3
-
87
-
-
33645217264
-
Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway
-
Korherr Ch., Gille H., Schafer R., et al. Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway. PNAS 2006, 103(11):4240-4245.
-
(2006)
PNAS
, vol.103
, Issue.11
, pp. 4240-4245
-
-
Korherr, C.1
Gille, H.2
Schafer, R.3
-
88
-
-
21244460271
-
Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression
-
Asosingh K., De Raeve H., de Ridder M., et al. Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression. Haematologica 2005, 90:810-817.
-
(2005)
Haematologica
, vol.90
, pp. 810-817
-
-
Asosingh, K.1
De Raeve, H.2
de Ridder, M.3
-
89
-
-
68849096240
-
Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myeloma cells to melphalan
-
Hu Y., Kirito K., Yoshida K., et al. Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myeloma cells to melphalan. Mol Cancer Ther 2009, 8(8):2329-2338.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.8
, pp. 2329-2338
-
-
Hu, Y.1
Kirito, K.2
Yoshida, K.3
-
90
-
-
78149468597
-
Low bone marrow oxygen tension and hypoxia-inducible factor-1a overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells
-
Colla S., Storti P., Donofrio G., et al. Low bone marrow oxygen tension and hypoxia-inducible factor-1a overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells. Leukemia 2010, 10.1038/leu.2010.193.
-
(2010)
Leukemia
-
-
Colla, S.1
Storti, P.2
Donofrio, G.3
-
91
-
-
77954995650
-
Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia inducible factor-1α
-
Paone A., Galli R., Gabellini Ch., et al. Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia inducible factor-1α. Neoplasia 2010, 12(7):539-549.
-
(2010)
Neoplasia
, vol.12
, Issue.7
, pp. 539-549
-
-
Paone, A.1
Galli, R.2
Gabellini, C.3
-
92
-
-
36849076158
-
Hypoxia inducible factor (HIF) function in innate immunity and infection
-
Zinkernagel A.S., Johnson R.S., Nizet V. Hypoxia inducible factor (HIF) function in innate immunity and infection. J Mol Med 2007, 85:1339-1346.
-
(2007)
J Mol Med
, vol.85
, pp. 1339-1346
-
-
Zinkernagel, A.S.1
Johnson, R.S.2
Nizet, V.3
-
93
-
-
68749113798
-
The involvement of hypoxia-inducible factor 1 alpha in Toll-like receptor 7/8-mediated inflammatory response
-
Nicholas S.A., Sumbayev V.V. The involvement of hypoxia-inducible factor 1 alpha in Toll-like receptor 7/8-mediated inflammatory response. Cell Res 2009, 19:973-983.
-
(2009)
Cell Res
, vol.19
, pp. 973-983
-
-
Nicholas, S.A.1
Sumbayev, V.V.2
-
94
-
-
43449117496
-
HIF-1α protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6
-
Lall H., Coughlan K., Sumbayev V.V. HIF-1α protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6. Mol Immunol 2008, 45:3045-3049.
-
(2008)
Mol Immunol
, vol.45
, pp. 3045-3049
-
-
Lall, H.1
Coughlan, K.2
Sumbayev, V.V.3
-
95
-
-
31544436323
-
Anti-myeloma activity of heat shock protein-90 inhibition
-
Mitsiades C.S., Mitsiades N.S., McMullan C.J., et al. Anti-myeloma activity of heat shock protein-90 inhibition. Blood 2006, 107:1092-1100.
-
(2006)
Blood
, vol.107
, pp. 1092-1100
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
-
96
-
-
59649086503
-
SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK
-
Okawa Y., Hideshima T., Steed P., et al. SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK. Blood 2009, 113:846-855.
-
(2009)
Blood
, vol.113
, pp. 846-855
-
-
Okawa, Y.1
Hideshima, T.2
Steed, P.3
-
97
-
-
44449174536
-
Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia
-
Kuhlicke J., Frick J.S., Morote-Garcia J.C., Rosenberger P., Eltzschig H.K. Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia. PLoS One 2007, 2(12):e1364.
-
(2007)
PLoS One
, vol.2
, Issue.12
-
-
Kuhlicke, J.1
Frick, J.S.2
Morote-Garcia, J.C.3
Rosenberger, P.4
Eltzschig, H.K.5
-
98
-
-
75749134893
-
Modulation of bone marrow stromal cell functions in infectious diseases by toll-like receptor ligands
-
Nemeth K., Mayer B., Mezey E. Modulation of bone marrow stromal cell functions in infectious diseases by toll-like receptor ligands. J Mol Med 2010, 88:5-10.
-
(2010)
J Mol Med
, vol.88
, pp. 5-10
-
-
Nemeth, K.1
Mayer, B.2
Mezey, E.3
-
99
-
-
0345268793
-
Hsp90 binds CpG oligonucleotides directly: implications for hsp90 as a missing link in CpG signaling and recognition
-
Bandholtz L., Guo Y., Palmberg C., et al. Hsp90 binds CpG oligonucleotides directly: implications for hsp90 as a missing link in CpG signaling and recognition. Cell Mol Life Sci 2003, 60(2):422-429.
-
(2003)
Cell Mol Life Sci
, vol.60
, Issue.2
, pp. 422-429
-
-
Bandholtz, L.1
Guo, Y.2
Palmberg, C.3
-
100
-
-
15444381172
-
A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by Toll-like receptors
-
De Nardo D., Masendycz P., Ho S., et al. A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by Toll-like receptors. J Biol Chem 2005, 280(11):9813-9822.
-
(2005)
J Biol Chem
, vol.280
, Issue.11
, pp. 9813-9822
-
-
De Nardo, D.1
Masendycz, P.2
Ho, S.3
-
101
-
-
1642432081
-
IL-6, RANKL, TNF-alpha/IL-1: interrelations in bone resorption pathophysiology
-
Steeve K.T., Marc P., Sandrine Th., Dominique H., Yannick F. IL-6, RANKL, TNF-alpha/IL-1: interrelations in bone resorption pathophysiology. Cytokine Growth F Rev 2004, 15:49-60.
-
(2004)
Cytokine Growth F Rev
, vol.15
, pp. 49-60
-
-
Steeve, K.T.1
Marc, P.2
Sandrine, T.3
Dominique, H.4
Yannick, F.5
-
102
-
-
0034284970
-
Bone resorption by osteoclasts
-
Teitelbaum S.L. Bone resorption by osteoclasts. Science 2000, 289:1504-1508.
-
(2000)
Science
, vol.289
, pp. 1504-1508
-
-
Teitelbaum, S.L.1
-
103
-
-
33846828518
-
Hyaluronan inhibits osteoclast differentiation via Toll-like receptor 4
-
Chang E.J., Kim H.J., Ha J., et al. Hyaluronan inhibits osteoclast differentiation via Toll-like receptor 4. J Cell Sci 2007, 120:166-176.
-
(2007)
J Cell Sci
, vol.120
, pp. 166-176
-
-
Chang, E.J.1
Kim, H.J.2
Ha, J.3
-
104
-
-
0033398996
-
Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kB (RANK) receptors
-
Arai F., Miyamoto T., Ohneda O., et al. Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kB (RANK) receptors. J Exp Med 1999, 190(12):1741-1754.
-
(1999)
J Exp Med
, vol.190
, Issue.12
, pp. 1741-1754
-
-
Arai, F.1
Miyamoto, T.2
Ohneda, O.3
-
105
-
-
0035284871
-
Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors
-
Kikuchi T., Matsuguchi T., Tsuboi N., et al. Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. J Immunol 2001, 166:3574-3579.
-
(2001)
J Immunol
, vol.166
, pp. 3574-3579
-
-
Kikuchi, T.1
Matsuguchi, T.2
Tsuboi, N.3
-
106
-
-
0033931495
-
Toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection
-
Hou L., Sasaki H., Stashenko Ph. Toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection. Infect Immun 2000, 68:4681-4687.
-
(2000)
Infect Immun
, vol.68
, pp. 4681-4687
-
-
Hou, L.1
Sasaki, H.2
Stashenko, P.3
-
107
-
-
0038269023
-
CpG oligodeoxynucleotides modulate the osteoclastogenic activity of osteoblasts via Toll-like receptor 9
-
Zou W., Amcheslavsky A., Bar-Shavit Z. CpG oligodeoxynucleotides modulate the osteoclastogenic activity of osteoblasts via Toll-like receptor 9. J Biol Chem 2003, 278:16732-16740.
-
(2003)
J Biol Chem
, vol.278
, pp. 16732-16740
-
-
Zou, W.1
Amcheslavsky, A.2
Bar-Shavit, Z.3
-
108
-
-
0036681842
-
Stimulation by toll-like receptors inhibits osteoclast differentiation
-
Takami M., Kim N., Rho J., Choi Y. Stimulation by toll-like receptors inhibits osteoclast differentiation. J Immunol 2002, 169:1516-1523.
-
(2002)
J Immunol
, vol.169
, pp. 1516-1523
-
-
Takami, M.1
Kim, N.2
Rho, J.3
Choi, Y.4
-
109
-
-
41749104586
-
The inflammatory response to cell death
-
Rock K.L., Kono H. The inflammatory response to cell death. Annu Rev Pathol Mech Dis 2008, 3:99-126.
-
(2008)
Annu Rev Pathol Mech Dis
, vol.3
, pp. 99-126
-
-
Rock, K.L.1
Kono, H.2
-
110
-
-
0036839577
-
Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses
-
Beg A.A. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol 2002, 23:509-511.
-
(2002)
Trends Immunol
, vol.23
, pp. 509-511
-
-
Beg, A.A.1
-
111
-
-
0037066427
-
The danger model: a renewed sense of self
-
Matzinger P. The danger model: a renewed sense of self. Science 2002, 296:301-305.
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
112
-
-
0033134764
-
Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma
-
Vacca A., Ribatti D., Presta M., et al. Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. Blood 1999, 93:3064-3073.
-
(1999)
Blood
, vol.93
, pp. 3064-3073
-
-
Vacca, A.1
Ribatti, D.2
Presta, M.3
-
113
-
-
0035986760
-
αvβ3 Integrin engagement enhances cell invasiveness in human multiple myeloma
-
Ria R., Vacca A., Ribatti D., Di Raimondo F., Merchionne F., Dammacco F. αvβ3 Integrin engagement enhances cell invasiveness in human multiple myeloma. Haematologica 2002, 87:836-845.
-
(2002)
Haematologica
, vol.87
, pp. 836-845
-
-
Ria, R.1
Vacca, A.2
Ribatti, D.3
Di Raimondo, F.4
Merchionne, F.5
Dammacco, F.6
-
114
-
-
33745840859
-
Hyaluronan fragments act as an endogenous danger signal by engaging TLR2
-
Scheibner K.A., Lutz M.A., Boodoo S., Fenton M.J., Powell J.D., Horton M.R. Hyaluronan fragments act as an endogenous danger signal by engaging TLR2. J Immunol 2006, 177:1272-1281.
-
(2006)
J Immunol
, vol.177
, pp. 1272-1281
-
-
Scheibner, K.A.1
Lutz, M.A.2
Boodoo, S.3
Fenton, M.J.4
Powell, J.D.5
Horton, M.R.6
-
115
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura Y., Watari M., Jerud E.S., et al. The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem 2001, 276(13):10229-10233.
-
(2001)
J Biol Chem
, vol.276
, Issue.13
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
-
116
-
-
33744479425
-
Inflammation and multiple myeloma: the Toll connection
-
Mantovani A., Garlanda C. Inflammation and multiple myeloma: the Toll connection. Leukemia 2006, 20:937-938.
-
(2006)
Leukemia
, vol.20
, pp. 937-938
-
-
Mantovani, A.1
Garlanda, C.2
-
117
-
-
33645461206
-
High mobility group box 1 protein interacts with multiple Toll-like receptors
-
Park J.S., Gamboni-Robertson F., He Q., et al. High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 2006, 290:C917-C924.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Park, J.S.1
Gamboni-Robertson, F.2
He, Q.3
-
118
-
-
1542380035
-
Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
Park J.S., Svetkauskaite D., He Q., et al. Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004, 279(9):7370-7377.
-
(2004)
J Biol Chem
, vol.279
, Issue.9
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
-
119
-
-
47649111320
-
HSP70 inhibition reverses cell adhesion mediated and acquired drug resistance in multiple myeloma
-
Nimmanapalli R., Gerbino E., Dalton W.S., Gandhi V., Alsina M. HSP70 inhibition reverses cell adhesion mediated and acquired drug resistance in multiple myeloma. Brit J Haematol 2008, 142:551-561.
-
(2008)
Brit J Haematol
, vol.142
, pp. 551-561
-
-
Nimmanapalli, R.1
Gerbino, E.2
Dalton, W.S.3
Gandhi, V.4
Alsina, M.5
-
120
-
-
0025757212
-
Medical history and the risk of multiple myeloma
-
Gramenzil A., Buttinol I., D'Avanzol B., Negri E., Franceschi S., Vecchia C.L. Medical history and the risk of multiple myeloma. Brit J Cancer 1991, 63:769-772.
-
(1991)
Brit J Cancer
, vol.63
, pp. 769-772
-
-
Gramenzil, A.1
Buttinol, I.2
D'Avanzol, B.3
Negri, E.4
Franceschi, S.5
Vecchia, C.L.6
-
121
-
-
43549084625
-
Risk of multiple myeloma and monoclonal gammopathy of undetermined significance among white and black male United States veterans with prior autoimmune, infectious, inflammatory, and allergic disorders
-
Brown L.M., Gridley G., Check D., Landgren O. Risk of multiple myeloma and monoclonal gammopathy of undetermined significance among white and black male United States veterans with prior autoimmune, infectious, inflammatory, and allergic disorders. Blood 2008, 111:3388-3394.
-
(2008)
Blood
, vol.111
, pp. 3388-3394
-
-
Brown, L.M.1
Gridley, G.2
Check, D.3
Landgren, O.4
-
123
-
-
0006893431
-
Human herpesvirus 8 in hematologic diseases
-
Mikala G., Xie J., Berencsi G., et al. Human herpesvirus 8 in hematologic diseases. Pathol Oncol Res 1999, 5(1).
-
(1999)
Pathol Oncol Res
, vol.5
, Issue.1
-
-
Mikala, G.1
Xie, J.2
Berencsi, G.3
-
124
-
-
55249114624
-
Toll-like receptor 4 mediates innate immunity to Kaposi sarcoma herpesvirus
-
Lagos D., Vart R.J., Gratrix F., et al. Toll-like receptor 4 mediates innate immunity to Kaposi sarcoma herpesvirus. Cell Host Microbe 2008, 4:470-483.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 470-483
-
-
Lagos, D.1
Vart, R.J.2
Gratrix, F.3
-
125
-
-
3242740205
-
Human cytomegalovirus protects multiple myeloma cell line KM3 from apoptosis induced by growth factor withdrawal
-
Guo-qing W., Mao-fang L., He H., Zhen C. Human cytomegalovirus protects multiple myeloma cell line KM3 from apoptosis induced by growth factor withdrawal. Chin Med J 2004, 117(6):903-907.
-
(2004)
Chin Med J
, vol.117
, Issue.6
, pp. 903-907
-
-
Guo-qing, W.1
Mao-fang, L.2
He, H.3
Zhen, C.4
-
126
-
-
0037180757
-
Inflammation and cancer
-
Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002, 420(6917):860-867.
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
127
-
-
33846211375
-
Inflammation, cancer and chemoresistance: taking advantage of toll-like receptor signaling pathway
-
Chen R., Alvero A.B., Silasi D.A., Mor G. Inflammation, cancer and chemoresistance: taking advantage of toll-like receptor signaling pathway. Am J Reprod Immunol 2007, 57:93-107.
-
(2007)
Am J Reprod Immunol
, vol.57
, pp. 93-107
-
-
Chen, R.1
Alvero, A.B.2
Silasi, D.A.3
Mor, G.4
-
128
-
-
4644324186
-
NF-kB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E., Porat R.M., Stein I., et al. NF-kB functions as a tumour promoter in inflammation-associated cancer. Nature 2004, 431:461-466.
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
-
129
-
-
0033121314
-
Role of NF-kappa B in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by Bcl-2
-
Feinman R., Koury J., Thames M., Barlogie B., Epstein J., Siegel D.S. Role of NF-kappa B in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by Bcl-2. Blood 1999, 93:3044-3052.
-
(1999)
Blood
, vol.93
, pp. 3044-3052
-
-
Feinman, R.1
Koury, J.2
Thames, M.3
Barlogie, B.4
Epstein, J.5
Siegel, D.S.6
-
130
-
-
34249677845
-
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
-
Kanzler H., Barrat F.J., Hessel E.M., Coffman R.L. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med 2007, 13(5):552-559.
-
(2007)
Nat Med
, vol.13
, Issue.5
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
Coffman, R.L.4
-
131
-
-
33845542139
-
Toll-like receptor agonists in the treatment of chronic lymphocytic leukemia
-
Spaner D.E., Masellis A. Toll-like receptor agonists in the treatment of chronic lymphocytic leukemia. Leukemia 2007, 21:53-60.
-
(2007)
Leukemia
, vol.21
, pp. 53-60
-
-
Spaner, D.E.1
Masellis, A.2
-
132
-
-
70449719118
-
Myeloma cell line derived, pooled heat shock proteins as a universal vaccine for immunotherapy of multiple myeloma
-
Qian J., Hong S., Wang S., et al. Myeloma cell line derived, pooled heat shock proteins as a universal vaccine for immunotherapy of multiple myeloma. Blood 2009, 114:3880-3889.
-
(2009)
Blood
, vol.114
, pp. 3880-3889
-
-
Qian, J.1
Hong, S.2
Wang, S.3
-
133
-
-
33750208645
-
Interference with nuclear factor kappa B and c-Jun NH2-terminal kinase signaling by TRAF6C small interfering RNA inhibits myeloma cell proliferation and enhances apoptosis
-
Chen H., Li M., Campbell R.A., et al. Interference with nuclear factor kappa B and c-Jun NH2-terminal kinase signaling by TRAF6C small interfering RNA inhibits myeloma cell proliferation and enhances apoptosis. Oncogene 2006, 25:6520-6527.
-
(2006)
Oncogene
, vol.25
, pp. 6520-6527
-
-
Chen, H.1
Li, M.2
Campbell, R.A.3
-
134
-
-
18544367201
-
NFκB as a therapeutic target in multiple myeloma
-
Hideshima T., Chauhan Dh., Richardson P., et al. NFκB as a therapeutic target in multiple myeloma. J Biol Chem 2002, 277(19):16639-16647.
-
(2002)
J Biol Chem
, vol.277
, Issue.19
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
-
135
-
-
0041381364
-
SIGIRR puts the brakes on Toll-like receptors
-
Luke A.J.O. SIGIRR puts the brakes on Toll-like receptors. Nat Immunol 2003, 4:823-824.
-
(2003)
Nat Immunol
, vol.4
, pp. 823-824
-
-
Luke, A.J.O.1
-
136
-
-
0042733592
-
SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling
-
Wald D., Qin J., Zhao Zh., et al. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol 2003, 4:920-927.
-
(2003)
Nat Immunol
, vol.4
, pp. 920-927
-
-
Wald, D.1
Qin, J.2
Zhao, Z.3
-
137
-
-
33644847257
-
Sensitization of IL-2 signaling through TLR-7 enhances B lymphoma cell immunogenicity
-
Tomic J., White D., Shi Y., et al. Sensitization of IL-2 signaling through TLR-7 enhances B lymphoma cell immunogenicity. J Immunol 2006, 176:3830-3839.
-
(2006)
J Immunol
, vol.176
, pp. 3830-3839
-
-
Tomic, J.1
White, D.2
Shi, Y.3
-
138
-
-
80053941090
-
Expression and function of toll like receptors in chronic lymphocytic leukaemia cells
-
Muzio M., Scielzo C., Bertilaccio M.T.S., Frenquelli M., Ghia P., Caligaris-Cappio F. Expression and function of toll like receptors in chronic lymphocytic leukaemia cells. Exp Hematol 2008, 28:558-568.
-
(2008)
Exp Hematol
, vol.28
, pp. 558-568
-
-
Muzio, M.1
Scielzo, C.2
Bertilaccio, M.T.S.3
Frenquelli, M.4
Ghia, P.5
Caligaris-Cappio, F.6
-
139
-
-
14244268126
-
Immunostimulatory oligodeoxynucleotides induce apoptosis of B cell chronic lymphocytic leukemia cells
-
Jahrsdörfer B., Wooldridge J.E., Blackwell S.E., et al. Immunostimulatory oligodeoxynucleotides induce apoptosis of B cell chronic lymphocytic leukemia cells. J Leukocyte Biol 2005, 77:378-387.
-
(2005)
J Leukocyte Biol
, vol.77
, pp. 378-387
-
-
Jahrsdörfer, B.1
Wooldridge, J.E.2
Blackwell, S.E.3
-
140
-
-
0035155134
-
CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens
-
Jahrsdörfer B., Hartmann G., Racila E., et al. CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens. J Leukocyte Biol 2001, 69:81-88.
-
(2001)
J Leukocyte Biol
, vol.69
, pp. 81-88
-
-
Jahrsdörfer, B.1
Hartmann, G.2
Racila, E.3
-
141
-
-
38949136279
-
Combined treatment of CpG-oligodeoxynucleotide with Nutlin-3 induces strong immune stimulation coupled to cytotoxicity in B-chronic lymphocytic leukemic (B-CLL) cells
-
Secchiero P., Melloni E., Tiribelli M., Gonelli A., Zauli G. Combined treatment of CpG-oligodeoxynucleotide with Nutlin-3 induces strong immune stimulation coupled to cytotoxicity in B-chronic lymphocytic leukemic (B-CLL) cells. J Leukocyte Biol 2008, 83:434-437.
-
(2008)
J Leukocyte Biol
, vol.83
, pp. 434-437
-
-
Secchiero, P.1
Melloni, E.2
Tiribelli, M.3
Gonelli, A.4
Zauli, G.5
-
142
-
-
33847702017
-
Toll-like receptor-7 tolerizes malignant B cells and enhances killing by cytotoxic agents
-
Shi Y., White D., He L., Miller R.L., Spaner D.E. Toll-like receptor-7 tolerizes malignant B cells and enhances killing by cytotoxic agents. Cancer Res 2007, 67(4):1823-1831.
-
(2007)
Cancer Res
, vol.67
, Issue.4
, pp. 1823-1831
-
-
Shi, Y.1
White, D.2
He, L.3
Miller, R.L.4
Spaner, D.E.5
-
143
-
-
31444457097
-
Immunomodulatory effects of Toll-like receptor-7 activation on chronic lymphocytic leukemia cells
-
Spaner D.E., Shi Y., White D., et al. Immunomodulatory effects of Toll-like receptor-7 activation on chronic lymphocytic leukemia cells. Leukaemia 2006, 20:286-295.
-
(2006)
Leukaemia
, vol.20
, pp. 286-295
-
-
Spaner, D.E.1
Shi, Y.2
White, D.3
-
144
-
-
33644850641
-
Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia
-
Corthals S.L., Wynne K., She K., et al. Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia. Brit J Haematol 2005, 132:452-458.
-
(2005)
Brit J Haematol
, vol.132
, pp. 452-458
-
-
Corthals, S.L.1
Wynne, K.2
She, K.3
-
145
-
-
18244390243
-
CpG stimulation of precursor B-lineage acute lymphoblastic leukemia induces a distinct change in costimulatory molecule expression and shifts allogeneic T cells toward a Th1 response
-
Reid G.S., She K., Terrett L., Food M.R., Trudeau J.D., Schultz K.R. CpG stimulation of precursor B-lineage acute lymphoblastic leukemia induces a distinct change in costimulatory molecule expression and shifts allogeneic T cells toward a Th1 response. Blood 2005, 105(9):3641-3647.
-
(2005)
Blood
, vol.105
, Issue.9
, pp. 3641-3647
-
-
Reid, G.S.1
She, K.2
Terrett, L.3
Food, M.R.4
Trudeau, J.D.5
Schultz, K.R.6
|