HIF-1α protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6

Molecular Immunology

Volumn 45, Issue 11, 2008, Pages 3045-3049

  Lall, Harjinder ^a   Coughlan, Karen ^a   Sumbayev, Vadim V ^a  

^a MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

Author keywords

Apoptosis; HIF 1 protein; Inflammation and innate immunity; Toll like receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; COBALT; COBALT CHLORIDE; MAP3K5 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEPLETION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; EXTRACELLULAR SPACE; GENETICS; IMMUNOLOGY; METABOLISM; TUMOR CELL LINE;

NEGIBACTERIA;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CELL LINE, TUMOR; COBALT; DOWN-REGULATION; EXTRACELLULAR SPACE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MAP KINASE KINASE KINASE 5; MYELOID CELLS; TOLL-LIKE RECEPTOR 4;

EID: 43449117496     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.03.014     Document Type: Article

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