Protective effect of a prostaglandin I2 analog, TEI-7165, on ischemic neuronal damage in gerbils

Brain Research

Volumn 769, Issue 2, 1997, Pages 321-328

  Matsuda, Seiji ^a   Wen, Tong Chun ^a   Karasawa, Yasuko ^b   Araki, Hiroaki ^c   Otsuka, Hiroki ^d   Ishihara, Ken ^d   Sakanaka, Masahiro ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

^c OKAYAMA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d OSAKA NATIONAL HOSPITAL   (Japan)

Author keywords

Brain ischemia; Delayed neuronal death; Gerbil; Passive avoidance task; Prostaglandin I2 analog; Synapse

Indexed keywords

CALCIUM CHANNEL; ISOCARBACYCLIN; ISOCARBACYCLIN METHYL ESTER; MICROSPHERE; PROSTACYCLIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN CIRCULATION; CONTROLLED STUDY; DRUG EFFECT; GERBIL; INTRAVENOUS DRUG ADMINISTRATION; ISCHEMIA; LATERAL BRAIN VENTRICLE; NERVE INJURY; NEUROPROTECTION; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RECEPTOR AFFINITY; THROMBOCYTE AGGREGATION;

ANIMALS; AVOIDANCE LEARNING; BRAIN; BRAIN ISCHEMIA; EPOPROSTENOL; GERBILLINAE; HIPPOCAMPUS; MALE; MICROSCOPY, ELECTRON; NEURONS; NEUROPROTECTIVE AGENTS; PYRAMIDAL CELLS; REACTION TIME; SYNAPSES;

EID: 0030783807     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00724-5     Document Type: Article

References (35)

1. Araki H., Nojiri M., Kawashima K., Kimura M., Aihara H. Behavioral, electroencephalographic and histopathological studies on Mongolian gerbils with occluded common carotid arteries. Physiol. Behav. 38:1986;89-94.
2. Awad I., Little J.R., Lucas F., Skrinska V., Slugg R., Lesser R.P. Treatment of acute focal cerebral ischemia with prostacyclin. Stroke. 4:1983;203-209.
3. Bonnekoh P., Barbier A., Oschlies U., Hossman K.A. Selective vulnerability in the gerbil hippocampus: Morphological changes after 5-min ischemia and long survival times. Acta Neuropathol. 80:1990;18-25.
4. Borzeix M.G., Cahn R., Cahn J. Effects of new chemically and metabolically stable prostacyclin analogues (iloprost and ZK 96480) on early consequence of a transient cerebral oligemia, in the rat. Prostaglandins. 35:1988;653-664.
5. Dusting G.J., Moncada S., Vane J.R. Disappearance of prostacyclin in the circulation of the dog. Br. J. Pharmacol. 62:1977;414-415.
6. Gryglewski R.J., Nowak S., Kostka-Trabka E., Kusmiderski J., Dembinska-Kiec A., Bieron K., Basista M., Blaszczyk B. Treatment of ischemic stroke with prostacyclin. Stroke. 14:1983;197-202.
7. 2+ levels? Eur. Neuropsychopharmacol. 6(supple):1996;195.
8. Hsu C.Y., Faught R.E. Jr., Furlan A.J., Coull B.M., Huang D.C., Hogan E.L., Linet O.I., Yatsu F.M. Intravenous prostacyclin in acute nonhemorrhagic stroke: A placebo-controlled double-blind trial. Stroke. 18:1987;352-358.
9. Karasawa Y., Nitatori T., Sato N., Araki H., Higashi S., Kominami E., Uchiyama Y. Effect of TTC-909 on apoptosis of CA1 pyramidal neurons in gerbil hippocampus after transient ischemia. Jpn. J. Pharmacol. 67(suppl.):1995;302.
10. Käser-Glanzmann R., Jakobova M., George J., Luscher E. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3′,5′-cyclic monophosphate and protein kinase. Biochim. Biophys. Acta. 466:1977;429-440.
11. Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 237:1982;57-69.
12. Kirino T., Tamura A., Sano K. Chronic maintenance of presynaptic terminals in gliotic hippocampus following ischemia. Brain Res. 510:1990;17-25.
13. Kotani Y., Matsuda S., Wen T.-C., Sakanaka M., Tanaka J., Maeda N., Kondoh K., Ueno S., Sano A. A hydrophilic peptide comprising 18 amino acid residues of the prosaposin sequence has neurotrophic activity in vitro and in vivo. J. Neurochem. 66:1996;2197-2200.
14. J.-H. Lim, T.-C. Wen, S. Matsuda, J. Tanaka, N. Maeda, H. Peng, J. Aburaya, K. Ishihara, M. Sakanaka, Protection of ischemic hippocampal neurons by ginsenoside Rb1, a main ingredient of ginseng root, Neurosci. Res. (1997) in press.
15. Martin J.F., Hamdy N., Nicholl J., Lewtas N., Bergvall U., Owen P., Syder D., Holroyd M. Double-blind controlled trial of prostacyclin in cerebral infarction. Stroke. 16:1985;386-390.
16. Matsuda S., Wen T.-C., Morita F., Otsuka H., Igase K., Yoshimura H., Sakanaka M. Interleukin-6 prevents ischemia-induced learning disability and neuronal and synaptic loss in gerbils. Neurosci. Lett. 204:1996;109-112.
17. 3H]iloprost. Neuroscience. 65:1995;493-503.
18. Miller V.T., Coull B.M., Yatsu F.M., Shan A.B., Beamer N.B. Prostacyclin infusion in acute cerebral infarction. Neurology. 34:1984;1431-1435.
19. 2 analogue. J. Pharm. Pharmacol. 48:1996;1016-1022.
20. Mitani A., Andou Y., Masuda S., Kataoka K. Transient forebrain ischemia of three-minute duration consistently induces severe neuronal damage in field CA1 of the hippocampus in the normothermic gerbil. Neurosci. Lett. 13:1991;171-174.
21. Mizushima Y., Igarashi R., Hoshi K., Sim A.K., Cleland N.E., Hayashi H., Goto J. Marked enhancement in antithrombotic activity of isocarbacyclin following its incorporation into lipid microspheres. Prostaglandins. 33:1987;161-168.
22. Moncada S. Biological importance of prostacyclin. VIIIth Gaddum Memorial Lecture. Br. J. Pharmacol. 76:1982;3-31.
23. Moncada S. Biology and therapeutic potential of prostacyclin. Stroke. 14:1983;157-168.
24. Nelson G.L. Prostaglandin oligomer: potential agents for the protection against the effects of oxygen deprivation. Adv. Exp. Med. Biol. 238:1988;359-382.
25. S. Ramón y Cajal, Histologie du Systéme Nerveux de l'Homme et des Vertebris, Tome II, Maloine, Paris, 1911.
26. Sano A., Matsuda S., Wen T.-C., Kotani Y., Kondoh K., Ueno S., Kakimoto Y., Yoshimura H., Sakanaka M. Protection by prosaposin against ischemia-induced learning disability and neuronal loss. Biochem. Biophys. Res. Commun. 204:1994;994-1000.
27. Sawada K., Aoki K., Katuura Y., Tanabe H., Kiyoki M., Araki H. Vasorelaxant effect of isocarbacycline methyl ester incorporated into lipid microspheres on isolated canine arteries. Arzneim.-Forsch./Drug Res. 45:1995;985-988.
28. Shima K., Umezawa H., Chigasaki H., Okuyama S., Araki H. Stable prostacyclin improves postischemic microcirculatory changes in hypertensive rats. Acta. Neurochir. (Wien). 137:1995;89-95.
29. Takechi H., Matsumura K., Watanabe Y., Kato K., Noyori R., Suzuki M., Watanabe Y. A novel subtype of the prostacycline receptor expressed in the central nervous system. J. Biol. Chem. 271:1996;5901-5906.
30. Tanaka K., Gotoh F., Fukuuchi Y., Amano T., Suzuki N., Uematsu D., Kawamura J., Yamawaki T., Itoh N., Obara K. Stable prostacyclin analogue preventing microcirculatory derangement in experimental cerebral ischemia in cats. Stroke. 19:1988;1267-1274.
31. D. Thiessen, Y. Yahr, The Gerbil in Behavioral Investigations, Mechanisms of Territoriality and Olfactory Communication, University of Texas Press, TX, 1977.
32. Wen T.-C., Matsuda S., Yoshimura H., Aburaya J., Kushihata F., Sakanaka M. Protective effect of basic fibroblast growth factor-heparin and neurotoxic effect of platelet factor 4 on ischemic neuronal loss and learning disability in gerbils. Neuroscience. 65:1995;513-521.
33. Wen T.-C., Matsuda S., Yoshimura H., Kawabe T., Sakanaka M. Ciliary neurotrophic factor prevents ischemia-induced learning disability and neuronal loss in gerbils. Neurosci. Lett. 191:1995;55-58.
34. Wen T.-C., Yoshimura H., Matsuda S., Lim J.-H., Sakanaka M. Ginseng root prevents learning disability and neuronal loss in gerbils with 5-minute forebrain ischemia. Acta Neuropathol. 91:1996;15-22.
35. Yamashita K., Kataoka Y., N-Nakashima M., S-Yamashita Y., Tanabe H., Araki H., Niwa M., Taniyama K. Neuroprotective effect of TTC-909, an isocarbacyclin methyl ester incorporated in lipid microspheres, on hippocampal delayed neuronal death of stroke-prone spontaneously hypertensive rats. Jpn. J. Pharmacol. 71:1996;351-355.