Human gene encoding prostacyclin synthase (PTGIS): Genomic organization, chromosomal localization, and promoter activity

Genomics

Volumn 36, Issue 2, 1996, Pages 296-304

  Yokoyama, Chieko ^a   Yabuki, Tomoko ^a   Inoue, Hiroyasu ^a   Tone, Yoshinori ^a   Hara, Shuntaro ^a   Hatae, Toshihisa ^a   Nagata, Masami ^b   Takahashi, Ei Ichi ^b   Tanabe, Tadashi ^a,c  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GLUCOCORTICOID; GUANINE; MESSENGER RNA; PROSTACYCLIN SYNTHASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; AORTA; ARTERY ENDOTHELIUM; ARTICLE; CATTLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 20Q; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; GENE STRUCTURE; GENOME; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

ANIMALIA; BOS TAURUS; BOVINAE; PRIMATES;

EID: 0030248632     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0465     Document Type: Article

References (54)

1. Breathnach, R., and Chambon, P. (1981). Organization and expression of eucaryotic split genes coding for proteins. Annu. Rev. Biochem. 50: 349-383.
2. Bredt, D. S., and Snyder, S. H. (1994). Nitric oxide: A physiologic messenger molecule. Annu. Rev. Biochem. 63: 175-195.
3. Chartain, N. A., Geller, D. A., Koty, P. P., Sitrin, N. F., Nussler, A. K., Hoffman, E. P., Billiar, T. R., Hutchinson, N. I., and Mudgett, J. S. (1994). Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene. J. Biol. Chem. 269: 6765-6772.
4. Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
5. Cohen, J. C., Cali, J. J., Jelinek, D. F., Mehrabian, M., Sparkes, R. S., Lusis, A. J., Russell, D. W., and Hobbs, H. H. (1992). Cloning of the human cholesterol 7α-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12. Genomics 14: 153-161.
6. Davidson, I., Xiao, J. H., Rosales, R., Staub, A., and Chambon, P. (1988). The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence. Cell 54: 931-942.
7. Fourney, R. M., Miyakoshi, J., Day, R. S., III, and Paterson, M. C. (1988). Northern blotting: Efficient RNA staining and transfer. Focus 10: 5-7.
8. Hamberg, M., Svensson, J., and Samuelsson, B. (1975). Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides. Proc. Natl. Acad. Sci. USA 72:2994-2998.
9. Hara, S., Miyata, A., Yokoyama, C., Inoue, H., Brugger, R., Lottspeich, F., Ullrich, V., and Tanabe, T. (1994). Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells. J. Biol. Chem. 269: 19897-19903.
10. Hara, S., Morishita, R., Tone, Y., Yokoyama, C., Inoue, H., Kaneda, Y., Ogihara, T., and Tanabe, T. (1995a). Overexpression of prostacyclin synthase inhibits growth of vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 216: 862-867.
11. Hara, S., Miyata, A., Yokoyama, C., Brugger, R., Lottspeich, F., Ullrich, V., and Tanabe, T. (1995b). Molecular cloning and expression of prostacyclin synthase from endothelial cells. Adv. Prostaglandin Thromboxane Leukotriene Res. 23: 121-123.
12. Inoue, H., Nanayama, T., Kara, S., Yokoyama, C., and Tanabe, T. (1994). The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells. FEBS Lett. 350: 51-54.
13. Inoue, H., Yokoyama, C., Hara, S., Tone, Y., and Tanabe, T. (1995). Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J. Biol. Chem. 270: 24965-24971.
14. Kawashima, I., Mita-Honjo, K., and Takiguchi, Y. (1992). Characterization of the primate-specific repetitive DNA element MER1. DNA Seq. 2: 313-318.
15. Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., and Maki, R. A. (1990). The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell 61: 113-124.
16. Kosaka, T., Miyata, A., Ihara, H., Hara, S., Sugimoto, T., Takeda, O., Takahashi, E., and Tanabe, T. (1994). Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2. Eur. J. Biochem. 221: 889-897.
17. Leegwater, P. A. J., Van der Vliet, P. C., Rupp, R. A. W., Nowock, J., and Sippel, A. E. (1986). Functional homology between the sequence-specific DNA-binding proteins nuclear factor I from HeLa cells and the TGGCA protein from chicken liver. EMBO J. 5: 381-386.
18. Lichter, P., Ledbetter, S. A., Ledbetter, D. H., and Ward, D. C. (1990). Fluorescence in situ hybridization with Alu and L1 polymerase chain reaction probes for rapid characterization of human chromosomes in hybrid cell lines. Proc. Natl. Acad. Sci. USA 87: 6634-6638.
19. MacNaul, K. L., and Hutchinson, N. I. (1993). Differential expression of iNOS and cNOS mRNA in human vascular smooth muscle cells and endothelial cells under normal and inflammatory conditions. Biochem. Biophys. Res. Commun. 196: 1330-1334.
20. Marsden, P. A., Heng, H. H. Q., Scherer, S. W., Stewart, R. J., Hall, A. V., Shi, X.-M., Tsui, L.-C., and Schappert, K. T. (1993). Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J. Biol. Chem. 268: 17478-17488.
21. McLennan, I. S., and MacDonald, R. E. (1991). Prostaglandin synthetase and prostacyclin synthetase in mature rat skeletal muscles: Immunohistochemical localisation to arterioles, tendons and connective tissues. J. Anat. 179: 243-253.
22. Miyahara, K., Kawamoto, T., Sase, K., Yui, Y., Toda, K., Yang, L.-X., Hattori, R., Aoyama, T., Yamamoto, Y., Doi, Y., Ogoshi, S., Hashimoto, K., Kawai, C., Sasayama, S., and Shizuta, Y. (1994). Cloning and structural characterization of the human endothelial nitric-oxide-synthase gene. Eur. J. Biochem. 223: 719-726.
23. Miyata, A., Hara, S., Yokoyama, C., Inoue, H., Ullrich, V., and Tanabe, T. (1994a). Molecular cloning and expression of human prostacyclin synthase. Biochem. Biophys. Res. Commun. 200: 1728-1734.
24. Miyata, A., Yokoyama, C., Ihara, H., Bando, S., Takeda, O., Takahashi, E., and Tanabe, T. (1994b). Characterization of the human gene (TBXAS1) encoding thromboxane synthase. Eur. J. Biochem. 224: 273-279.
25. 2, and prostacyclin. Pharmacol Rev. 30: 293-331.
26. Moncada, S., and Vane, J. R. (1979). Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls. N. Engl. J. Med. 300: 1142-1147.
27. Nathan, C. (1992). Nitric oxide as a secretory product of mammalian cells. FASEB J. 6: 3051-3064.
28. Nathan, C., and Xie, Q.-w. (1994). Nitric oxide synthases: Roles, tolls, and controls. Cell 78: 915-918.
29. Needleman, P., Turk, J., Jakshik, B. A., Morrison, A. R., and Lefkowith, J. B. (1986). Arachidonic acid metabolism. Annu. Rev. Biochem. 55: 69-102.
30. Nimer, S., Fraser, J., Richards, J., Lynch, M., and Gasson, J. (1990). The repeated sequence CATT(A/T) is required for granulocyte-macrophage colony-stimulating factor promoter activity. J. Mol. Cell. Biol. 10: 6084-6088.
31. Nishida, K., Harrison, D. G., Navas, J. P., Fisher, A. A., Dockery, S. P., Uematsu, M., Nerem, R. M., Alexander, R. W., and Murphy, T. J. (1992). Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. J. Clin. Invest. 90: 2092-2096.
32. Nishimoto, M., Noshiro, M., and Okuda, K. (1993). Structure of the gene encoding human liver cholesterol 7α-hydroxylase. Biochim. Biophys. Acta 1172: 147-150.
33. Noshiro, M., and Okuda, K. (1990). Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7α-hydroxylase. FEBS Lett. 268: 137-140.
34. Okret, S., Poellinger, L., Dong, Y., and Gustafsson, J.-Å. (1986). Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone. Proc. Natl. Acad. Sci. USA 83: 5899-5903.
35. Orkin, S. H. (1990). Globin gene regulation and switching: Circa 1990. Cell 63: 665-672.
36. Pereira, B., Wu, K. K., and Wang, L. H. (1994). Molecular cloning and characterization of bovine prostacyclin synthase. Biochem. Biophys. Res. Commun. 203: 59-66.
37. Resnick, N., Collins, T., Atkinson, W., Bonthron, D., Dewey, C. F., Jr., and Gimbrone, M. A., Jr. (1993). Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc. Natl. Acad. Sci. USA 90: 4591-4595.
38. Reynolds, G. A., Basu, S. K., Osborne, T. F., Chin, D. J., Gil, G., Brown, M. S., Goldstein, J. L., and Luskey, K. L. (1984). HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions. Cell 38: 275-285.
39. 2 synthase antigen in smooth muscle cells. J. Biol. Chem. 258: 5922-5926.
40. Sun, F. F., Chapman, J. P., and McGuire, J. C. (1977). Metabolism of prostaglandin endoperoxide in animal tissues. Prostaglandins 14: 1055-1074.
41. Takahashi, E., Hori, T., O'Connell, P., Leppert, M., and White, R. (1990). R-banding and nonisotopic in situ hybridization: Precise localization of the human type II collagen gene (COL2A1). Hum. Genet. 86: 14-16.
42. Takahashi, E., Yamauchi, M., Tsuji, H., Hitomi, A., Meuth, M., and Hori, T. (1991). Chromosome mapping of the human cytidine-5′-triphosphate synthetase (CTPS) gene to band 1p34.1-p34.3 by fluorescence in situ hybridization. Hum. Genet. 88: 119-121.
43. Tanabe, T., and Ullrich, V. (1995). Prostacyclin and thromboxane synthases. J. Lipid Mediators Cell Signal. 12: 243-255.
44. Ullrich, V., and Nüsing, R. (1990). Thromboxane synthase. From isolation to function. Stroke 21(Suppl. IV): IV134-IV138.
45. Ullrich, V., and Brugger, R. (1994). Prostacyclin and thromboxane synthase: New aspects of hemethiolate catalysis. Angew. Chem. Int. Ed. Engl. 33: 1911-1919.
46. Vaccaro, M., Pawlak, A., and Jost, J.-P. (1990). Positive and negative regulatory elements of chicken vitellogenin II gene characterized by in vitro transcription competition assays in a homologous system. Proc. Natl. Acad. Sci. USA 87: 3047-3051.
47. Vane, J. R., and Botting, R. M. (1995). Pharmacodynamic profile of prostacyclin. Am. J. Cardiol. 75: 3A-10A.
48. Weiner, C. P., Lizasoain, I., Baylis, S. A., Knowles, R. G., Charles, I. G., and Moncada, S. (1994). Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc. Natl. Acad. Sci. USA 91: 5212-5216.
49. Xiao, J. H., Davidson, I., Macchi, M., Resales, R., Vigneron, M., Staub, A., and Chambon, P. (1987). In vitro binding of several cell-specific and ubiquitous nuclear proteins to the GT-I motif of the SV40 enhancer. Genes Dev. 1: 794-807.
50. Yamamoto, M., Ko, L. J., Leonald, M. W., Beug, H., Orkin, S. H., and Engel, J. D. (1990). Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. Genes Dev. 4: 1650-1662.
51. Yang, Z., Sugawara, M., Ponath, P. D., Wessendorf, L., Banerji, J., Li, Y., and Strominger, J. L. (1990). Interferon γ response region in the promoter of the human DPA gene. Proc. Natl. Acad. Sci. USA 87: 9226-9230.
52. Yokoyama, C., Miyata, A., Ihara, H., Ullrich, V., and Tanabe, T. (1991). Molecular cloning of human platelet thromboxane A synthase. Biochem. Biophys. Res. Commun. 178: 1479-1484.
53. Yokoyama, C., and Tanabe, T. (1989). Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme. Biochem. Biophys. Res. Commun. 165: 888-894.
54. Yoshida, K, Narita, M., and Fujinaga, K. (1989). Binding sites of HeLa cell nuclear proteins on the upstream region of adenovirus type 5 E1A gene. Nucleic Acids Res. 17: 10015-10034.