15(S)-HETE production in human retinal microvascular endothelial cells by hypoxia: Novel role for MEK1 in 15(S)-HETE-induced angiogenesis

Investigative Ophthalmology and Visual Science

Volumn 48, Issue 11, 2007, Pages 4930-4938

  Bajpai, Arun K ^a   Blaskova, Eva ^a   Pakala, Suresh B ^a   Zhao, Tieqiang ^a   Glasgow, Wayne C ^b   Penn, John S ^c   Johnson, Dianna A ^a   Rao, Gadiparthi N ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; 15 LIPOOXYGENASE 1; 15 LIPOOXYGENASE 2; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONIC ACID; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 15 HYDROXY 5,8,11,13 ICOSATETRAENOIC ACID; 15-HYDROXY-5,8,11,13-EICOSATETRAENOIC ACID; ALOX15B PROTEIN, HUMAN; ENZYME INHIBITOR; HYDROXYICOSATETRAENOIC ACID; MAP2K1 PROTEIN, HUMAN; STRESS ACTIVATED PROTEIN KINASE 1;

ARTICLE; BASEMENT MEMBRANE; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HYPOXIA; METABOLITE; MUTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RETINA CELL; RETINA NEOVASCULARIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VASCULAR ENDOTHELIUM; ADENOVIRUS; ANOXIA; BIOSYNTHESIS; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG ANTAGONISM; GENE VECTOR; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RETINA BLOOD VESSEL; TIME;

ADENOVIRIDAE; ANOXIA; ARACHIDONATE 15-LIPOXYGENASE; BASEMENT MEMBRANE; CELL MOVEMENT; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENETIC VECTORS; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 8; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS;

EID: 38449100614     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.07-0617     Document Type: Article

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