Peroxynitrite inactivates prostacyclin synthase by heme-thiolate- catalyzed tyrosine nitration

Drug Metabolism Reviews

Volumn 31, Issue 2, 1999, Pages 343-349

  Zou, Minghui ^a   Yesilkaya, Akin ^a,b   Ullrich, Volker ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b AKDENIZ UNIVERSITY   (Turkey)

Author keywords

Cyochrome P450; Endothelial cell; Nitric oxide; Superoxide

Indexed keywords

CYTOCHROME P450; HEME DERIVATIVE; NITRIC OXIDE; PEROXYNITRITE; PROSTACYCLIN; PROSTACYCLIN SYNTHASE; SUPEROXIDE; TYROSINE;

ANTIOXIDANT ACTIVITY; BLOOD VESSEL TONE; CATALYSIS; CONFERENCE PAPER; ENDOTHELIUM CELL; ENZYME INACTIVATION; INFLAMMATION; MESANGIUM CELL; NITRATION; PATHOPHYSIOLOGY; REPERFUSION INJURY; TISSUE DISTRIBUTION; TISSUE INJURY; VASODILATATION;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; EPOPROSTENOL; HEME; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; NITRATES; NITRIC OXIDE; SULFHYDRYL COMPOUNDS; SUPEROXIDES; TYROSINE; VASCULAR RESISTANCE;

EID: 0032925359     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.1081/DMR-100101922     Document Type: Conference Paper

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