PI3K-mTORC1 attenuates stress response by inhibiting cap-independent Hsp70 translation

Journal of Biological Chemistry

Volumn 286, Issue 8, 2011, Pages 6791-6800

  Sun, Jun ^a   Conn, Crystal S ^a   Han, Yan ^a   Yeung, Vincent ^a   Qian, Shu Bing ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGE-RELATED; CAP-INDEPENDENT TRANSLATION; CELLULAR PROCESS; CELLULAR PROTEINS; HEAT SHOCK PROTEIN; IN-CELL; INTERNAL RIBOSOME ENTRY SITE; NUTRIENT AVAILABILITY; PLAUSIBLE MECHANISMS; PROTEIN SYNTHESIS; REGULATORY MECHANISM; STRESS CONDITION; STRESS RESISTANCE; STRESS RESPONSE; STRESS-INDUCED; TRANSCRIPTIONAL REGULATION; TUBEROUS SCLEROSIS; UP-REGULATION;

GENES; MACHINERY; NUCLEIC ACIDS; SIGNALING;

PROTEINS;

HEAT SHOCK PROTEIN 70; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; TUBERIN;

5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE; GENETIC REGULATION; HSP70 GENE; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA CAPPING; RNA TRANSLATION; SIGNAL TRANSDUCTION; STRESS; UPREGULATION;

5' UNTRANSLATED REGIONS; ANIMALS; CELL LINE; HSP70 HEAT-SHOCK PROTEINS; MICE; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BIOSYNTHESIS; PROTEINS; RNA CAPS; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 79953171531     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.172882     Document Type: Article

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