Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 37, 2005, Pages 13075-13080

  Chan, Betty ^a   Greenan, Garrett ^a   McKeon, Frank ^a   Ellenberger, Tom ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Calcipressin; Inhibitor; Phosphatase

Indexed keywords

CALCINEURIN; CALCINEURIN INHIBITOR; CYCLOPHILIN A; CYCLOSPORIN A; FK 506 BINDING PROTEIN; PROTEIN DSCR1; TACROLIMUS; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME REGULATION; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION INITIATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANILINE COMPOUNDS; ANIMALS; BINDING SITES; CALCINEURIN; CELL LINE; CRICETINAE; DNA-BINDING PROTEINS; EXONS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; MUSCLE PROTEINS; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; ORGANOPHOSPHORUS COMPOUNDS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; TRANSCRIPTION FACTORS;

EID: 24944484976     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0503846102     Document Type: Article

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