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Volumn 32, Issue 4, 2011, Pages 146-150

Regulating Il9 transcription in T helper cells

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 9; TRANSCRIPTION FACTOR;

EID: 79953096442     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2011.01.006     Document Type: Review
Times cited : (76)

References (50)
  • 1
    • 0028077321 scopus 로고
    • IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma
    • Schmitt E., et al. IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma. J. Immunol. 1994, 153:3989-3996.
    • (1994) J. Immunol. , vol.153 , pp. 3989-3996
    • Schmitt, E.1
  • 2
    • 77952584843 scopus 로고    scopus 로고
    • The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation
    • Chang H.C., et al. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat. Immunol. 2010, 11:527-534.
    • (2010) Nat. Immunol. , vol.11 , pp. 527-534
    • Chang, H.C.1
  • 3
    • 56349093347 scopus 로고    scopus 로고
    • IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells
    • Dardalhon V., et al. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat. Immunol. 2008, 9:1347-1355.
    • (2008) Nat. Immunol. , vol.9 , pp. 1347-1355
    • Dardalhon, V.1
  • 4
    • 56349154943 scopus 로고    scopus 로고
    • Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
    • Veldhoen M., et al. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat. Immunol. 2008, 9:1341-1346.
    • (2008) Nat. Immunol. , vol.9 , pp. 1341-1346
    • Veldhoen, M.1
  • 5
    • 79953107993 scopus 로고    scopus 로고
    • A Brief History of IL-9
    • Goswami R., Kaplan M.H. A Brief History of IL-9. J. Immunol. 2011, 186:3283-3288.
    • (2011) J. Immunol. , vol.186 , pp. 3283-3288
    • Goswami, R.1    Kaplan, M.H.2
  • 6
    • 77957228169 scopus 로고    scopus 로고
    • Cellular sources and immune functions of interleukin-9
    • Noelle R.J., Nowak E.C. Cellular sources and immune functions of interleukin-9. Nat. Rev. Immunol. 2010, 10:683-687.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 683-687
    • Noelle, R.J.1    Nowak, E.C.2
  • 7
    • 33748792017 scopus 로고    scopus 로고
    • P38 MAP kinase drives the expression of mast cell-derived IL-9 via activation of the transcription factor GATA-1
    • Stassen M., et al. p38 MAP kinase drives the expression of mast cell-derived IL-9 via activation of the transcription factor GATA-1. Mol. Immunol. 2007, 44:926-933.
    • (2007) Mol. Immunol. , vol.44 , pp. 926-933
    • Stassen, M.1
  • 8
    • 77952583601 scopus 로고    scopus 로고
    • PU.1 regulates TCR expression by modulating GATA-3 activity
    • Chang H.C., et al. PU.1 regulates TCR expression by modulating GATA-3 activity. J. Immunol. 2009, 183:4887-4894.
    • (2009) J. Immunol. , vol.183 , pp. 4887-4894
    • Chang, H.C.1
  • 9
    • 20444502955 scopus 로고    scopus 로고
    • PU.1 expression delineates heterogeneity in primary Th2 cells
    • Chang H.C., et al. PU.1 expression delineates heterogeneity in primary Th2 cells. Immunity 2005, 22:693-703.
    • (2005) Immunity , vol.22 , pp. 693-703
    • Chang, H.C.1
  • 10
    • 77955902281 scopus 로고    scopus 로고
    • Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
    • Staudt V., et al. Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 2010, 33:192-202.
    • (2010) Immunity , vol.33 , pp. 192-202
    • Staudt, V.1
  • 11
    • 68149125188 scopus 로고    scopus 로고
    • IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines
    • Ahyi A.N., et al. IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines. J. Immunol. 2009, 183:1598-1606.
    • (2009) J. Immunol. , vol.183 , pp. 1598-1606
    • Ahyi, A.N.1
  • 12
    • 34548128307 scopus 로고    scopus 로고
    • The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4
    • Brustle A., et al. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat. Immunol. 2007, 8:958-966.
    • (2007) Nat. Immunol. , vol.8 , pp. 958-966
    • Brustle, A.1
  • 13
    • 0037015052 scopus 로고    scopus 로고
    • Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4
    • Lohoff M., et al. Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:11808-11812.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 11808-11812
    • Lohoff, M.1
  • 14
    • 3242878193 scopus 로고    scopus 로고
    • ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes
    • Ovcharenko I., et al. ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes. Nucleic Acids Res. 2004, 32:W280-W286.
    • (2004) Nucleic Acids Res. , vol.32
    • Ovcharenko, I.1
  • 15
    • 3242888285 scopus 로고    scopus 로고
    • RVISTA 2. 0: evolutionary analysis of transcription factor binding sites
    • Loots G.G., Ovcharenko I. rVISTA 2. 0: evolutionary analysis of transcription factor binding sites. Nucleic Acids Res. 2004, 32:W217-W221.
    • (2004) Nucleic Acids Res. , vol.32
    • Loots, G.G.1    Ovcharenko, I.2
  • 16
    • 38549096565 scopus 로고    scopus 로고
    • JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update
    • Bryne J.C., et al. JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update. Nucleic Acids Res. 2008, 36:D102-D106.
    • (2008) Nucleic Acids Res. , vol.36
    • Bryne, J.C.1
  • 17
    • 18744377964 scopus 로고    scopus 로고
    • Crystal structure of PU.1/IRF-4/DNA ternary complex
    • Escalante C.R., et al. Crystal structure of PU.1/IRF-4/DNA ternary complex. Mol. Cell 2002, 10:1097-1105.
    • (2002) Mol. Cell , vol.10 , pp. 1097-1105
    • Escalante, C.R.1
  • 18
    • 0035313207 scopus 로고    scopus 로고
    • IL-9 and IL-13 production by activated mast cells is strongly enhanced in the presence of lipopolysaccharide: NF-kappa B is decisively involved in the expression of IL-9
    • Stassen M., et al. IL-9 and IL-13 production by activated mast cells is strongly enhanced in the presence of lipopolysaccharide: NF-kappa B is decisively involved in the expression of IL-9. J. Immunol. 2001, 166:4391-4398.
    • (2001) J. Immunol. , vol.166 , pp. 4391-4398
    • Stassen, M.1
  • 19
    • 0029949409 scopus 로고    scopus 로고
    • Multiple transcription factors are required for activation of human interleukin 9 gene in T cells
    • Zhu Y.X., et al. Multiple transcription factors are required for activation of human interleukin 9 gene in T cells. J. Biol. Chem. 1996, 271:15815-15822.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15815-15822
    • Zhu, Y.X.1
  • 20
    • 0027717408 scopus 로고
    • Differential regulation of IL-9-expression after infection with Leishmania major in susceptible and resistant mice
    • Gessner A., et al. Differential regulation of IL-9-expression after infection with Leishmania major in susceptible and resistant mice. Immunobiology 1993, 189:419-435.
    • (1993) Immunobiology , vol.189 , pp. 419-435
    • Gessner, A.1
  • 21
    • 77955498891 scopus 로고    scopus 로고
    • Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development
    • Takimoto T., et al. Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development. J. Immunol. 2010, 185:842-855.
    • (2010) J. Immunol. , vol.185 , pp. 842-855
    • Takimoto, T.1
  • 22
    • 0029965236 scopus 로고    scopus 로고
    • Reversibility of T helper 1 and 2 populations is lost after long-term stimulation
    • Murphy E., et al. Reversibility of T helper 1 and 2 populations is lost after long-term stimulation. J. Exp. Med. 1996, 183:901-913.
    • (1996) J. Exp. Med. , vol.183 , pp. 901-913
    • Murphy, E.1
  • 23
    • 67650650890 scopus 로고    scopus 로고
    • Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
    • Bending D., et al. Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J. Clin. Invest. 2009, 119:565-572.
    • (2009) J. Clin. Invest. , vol.119 , pp. 565-572
    • Bending, D.1
  • 24
    • 58149251898 scopus 로고    scopus 로고
    • Late developmental plasticity in the T helper 17 lineage
    • Lee Y.K., et al. Late developmental plasticity in the T helper 17 lineage. Immunity 2009, 30:92-107.
    • (2009) Immunity , vol.30 , pp. 92-107
    • Lee, Y.K.1
  • 25
    • 60549086638 scopus 로고    scopus 로고
    • Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells
    • Martin-Orozco N., et al. Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. Eur. J. Immunol. 2009, 39:216-224.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 216-224
    • Martin-Orozco, N.1
  • 26
    • 33748174156 scopus 로고    scopus 로고
    • T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype
    • Mathur A.N., et al. T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood 2006, 108:1595-1601.
    • (2006) Blood , vol.108 , pp. 1595-1601
    • Mathur, A.N.1
  • 27
    • 58149190437 scopus 로고    scopus 로고
    • Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells
    • Shi G., et al. Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells. J. Immunol. 2008, 181:7205-7213.
    • (2008) J. Immunol. , vol.181 , pp. 7205-7213
    • Shi, G.1
  • 28
    • 78649539346 scopus 로고    scopus 로고
    • IFN-gamma and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells
    • Lexberg M.H., et al. IFN-gamma and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells. Eur. J. Immunol. 2010, 40:3017-3027.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 3017-3027
    • Lexberg, M.H.1
  • 29
    • 58149216715 scopus 로고    scopus 로고
    • Th memory for interleukin-17 expression is stable in vivo
    • Lexberg M.H., et al. Th memory for interleukin-17 expression is stable in vivo. Eur. J. Immunol. 2008, 38:2654-2664.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2654-2664
    • Lexberg, M.H.1
  • 30
    • 58749105841 scopus 로고    scopus 로고
    • IL-23 promotes maintenance but not commitment to the Th17 lineage
    • Stritesky G.L., et al. IL-23 promotes maintenance but not commitment to the Th17 lineage. J. Immunol. 2008, 181:5948-5955.
    • (2008) J. Immunol. , vol.181 , pp. 5948-5955
    • Stritesky, G.L.1
  • 31
    • 77953238901 scopus 로고    scopus 로고
    • Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage
    • Mukasa R., et al. Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage. Immunity 2010, 32:616-627.
    • (2010) Immunity , vol.32 , pp. 616-627
    • Mukasa, R.1
  • 32
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • Wei G., et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 2009, 30:155-167.
    • (2009) Immunity , vol.30 , pp. 155-167
    • Wei, G.1
  • 33
    • 65549114338 scopus 로고    scopus 로고
    • IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells
    • King I.L., Mohrs M. IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J. Exp. Med. 2009, 206:1001-1007.
    • (2009) J. Exp. Med. , vol.206 , pp. 1001-1007
    • King, I.L.1    Mohrs, M.2
  • 34
    • 62849090439 scopus 로고    scopus 로고
    • Cytokine-secreting follicular T cells shape the antibody repertoire
    • Reinhardt R.L., et al. Cytokine-secreting follicular T cells shape the antibody repertoire. Nat. Immunol. 2009, 10:385-393.
    • (2009) Nat. Immunol. , vol.10 , pp. 385-393
    • Reinhardt, R.L.1
  • 35
    • 65549134481 scopus 로고    scopus 로고
    • T follicular helper cells differentiate from Th2 cells in response to helminth antigens
    • Zaretsky A.G., et al. T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J. Exp. Med. 2009, 206:991-999.
    • (2009) J. Exp. Med. , vol.206 , pp. 991-999
    • Zaretsky, A.G.1
  • 36
    • 48249084200 scopus 로고    scopus 로고
    • Flexibility accompanies commitment of memory CD4 lymphocytes derived from IL-4 locus-activated precursors
    • Adeeku E., et al. Flexibility accompanies commitment of memory CD4 lymphocytes derived from IL-4 locus-activated precursors. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:9307-9312.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 9307-9312
    • Adeeku, E.1
  • 37
    • 74549179138 scopus 로고    scopus 로고
    • Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions
    • Hegazy A.N., et al. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions. Immunity 2010, 32:116-128.
    • (2010) Immunity , vol.32 , pp. 116-128
    • Hegazy, A.N.1
  • 38
    • 34249079176 scopus 로고    scopus 로고
    • Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
    • Acosta-Rodriguez E.V., et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol. 2007, 8:639-646.
    • (2007) Nat. Immunol. , vol.8 , pp. 639-646
    • Acosta-Rodriguez, E.V.1
  • 39
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov I.I., et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006, 126:1121-1133.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1
  • 40
    • 44449136105 scopus 로고    scopus 로고
    • Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases
    • Liu X., et al. Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases. J. Immunol. 2008, 180:6070-6076.
    • (2008) J. Immunol. , vol.180 , pp. 6070-6076
    • Liu, X.1
  • 41
    • 34547734621 scopus 로고    scopus 로고
    • Phenotypic and functional features of human Th17 cells
    • Annunziato F., et al. Phenotypic and functional features of human Th17 cells. J. Exp. Med. 2007, 204:1849-1861.
    • (2007) J. Exp. Med. , vol.204 , pp. 1849-1861
    • Annunziato, F.1
  • 42
    • 73149118287 scopus 로고    scopus 로고
    • Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4
    • Cosmi L., et al. Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4. J. Allergy Clin. Immunol. 2010, 125:222-230.
    • (2010) J. Allergy Clin. Immunol. , vol.125 , pp. 222-230
    • Cosmi, L.1
  • 43
    • 78149326083 scopus 로고    scopus 로고
    • A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma
    • Wang Y.H., et al. A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J. Exp. Med. 2010, 207:2479-2491.
    • (2010) J. Exp. Med. , vol.207 , pp. 2479-2491
    • Wang, Y.H.1
  • 44
    • 77958584113 scopus 로고    scopus 로고
    • Generation of pathogenic T(H)17 cells in the absence of TGF-beta signalling
    • Ghoreschi K., et al. Generation of pathogenic T(H)17 cells in the absence of TGF-beta signalling. Nature 2010, 467:967-971.
    • (2010) Nature , vol.467 , pp. 967-971
    • Ghoreschi, K.1
  • 45
    • 69149107148 scopus 로고    scopus 로고
    • IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells
    • Elyaman W., et al. IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:12885-12890.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 12885-12890
    • Elyaman, W.1
  • 46
    • 68149179251 scopus 로고    scopus 로고
    • IL-9 as a mediator of Th17-driven inflammatory disease
    • Nowak E.C., et al. IL-9 as a mediator of Th17-driven inflammatory disease. J. Exp. Med. 2009, 206:1653-1660.
    • (2009) J. Exp. Med. , vol.206 , pp. 1653-1660
    • Nowak, E.C.1
  • 47
    • 78650666947 scopus 로고    scopus 로고
    • Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site
    • Tan C., et al. Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site. J. Immunol. 2010, 185:6795-6801.
    • (2010) J. Immunol. , vol.185 , pp. 6795-6801
    • Tan, C.1
  • 48
    • 73349109145 scopus 로고    scopus 로고
    • Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
    • Jager A., et al. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J. Immunol. 2009, 183:7169-7177.
    • (2009) J. Immunol. , vol.183 , pp. 7169-7177
    • Jager, A.1
  • 49
    • 78751701435 scopus 로고    scopus 로고
    • The transcription factor STAT3 is required for T helper 2 cell development
    • Stritesky G.L., et al. The transcription factor STAT3 is required for T helper 2 cell development. Immunity 2011, 34:39-49.
    • (2011) Immunity , vol.34 , pp. 39-49
    • Stritesky, G.L.1
  • 50
    • 0344064893 scopus 로고    scopus 로고
    • Stat5 activation plays a critical role in Th2 differentiation
    • Zhu J., et al. Stat5 activation plays a critical role in Th2 differentiation. Immunity 2003, 19:739-748.
    • (2003) Immunity , vol.19 , pp. 739-748
    • Zhu, J.1


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