p38 MAP kinase drives the expression of mast cell-derived IL-9 via activation of the transcription factor GATA-1

Molecular Immunology

Volumn 44, Issue 5, 2007, Pages 926-933

  Stassen, Michael ^a   Klein, Matthias ^a   Becker, Marc ^a   Bopp, Tobias ^a   Neudörfl, Christine ^a   Richter, Christoph ^a   Heib, Valeska ^a   Klein Hessling, Stefan ^b   Serfling, Edgar ^b   Schild, Hansjörg ^a   Schmitt, Edgar ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cytokines; Mast cells; Signal transduction

Indexed keywords

INTERLEUKIN 9; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSCRIPTION FACTOR GATA 1;

ANIMAL CELL; ARTICLE; BONE MARROW; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; FEMALE; IN VITRO STUDY; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TH2 CELL;

ANIMALS; BONE MARROW CELLS; FEMALE; GATA1 TRANSCRIPTION FACTOR; GATA2 TRANSCRIPTION FACTOR; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; INTERLEUKIN-9; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; MUTATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; RNA, MESSENGER; TH2 CELLS;

MURINAE;

EID: 33748792017     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.03.019     Document Type: Article

References (47)

1. Altschmied J., and Duschl J. Set of optimized luciferase reporter gene plasmids compatible with widely used CAT vectors. Biotechniques 23 (1997) 436-438
2. Baniyash M., and Eshhar Z. Inhibition of IgE binding to mast cells and basophils by monoclonal antibodies to murine IgE. Eur. J. Immunol. 14 (1984) 799-807
3. Cherwinski H.M., Schumacher J.H., Brown K.D., and Mosmann T.R. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. J. Exp. Med. 166 (1987) 1229-1244
4. Crossley M., and Orkin S.H. Phosphorylation of the erythroid transcription factor GATA-1. J. Biol. Chem. 269 (1994) 16589-16596
5. Davies S.P., Reddy H., Caivano M., and Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351 (2000) 95-105
6. Eshhar Z., Ofarim M., and Waks T. Generation of hybridomas secreting murine reaginic antibodies of anti-DNP specificity. J. Immunol. 124 (1980) 775-780
7. Gachter T., Moritz D.R., Gheyselinck J., and Klemenz R. GATA-Dependent expression of the interleukin-1 receptor-related T1 gene in mast cells. Mol. Cell Biol. 18 (1998) 5320-5331
8. Gounni A.S., Nutku E., Koussih L., Aris F., Louahed J., Levitt R.C., Nicolaides N.C., and Hamid Q. IL-9 expression by human eosinophils: regulation by IL-1beta and TNF-alpha. J. Allergy Clin. Immunol. 106 (2000) 460-466
9. Gross J.A., Callas E., and Allison J.P. Identification and distribution of the costimulatory receptor CD28 in the mouse. J. Immunol. 149 (1992) 380-388
10. Hansen A.S., Noren O., Sjostrom H., and Werdelin O. A mouse aminopeptidase N is a marker for antigen-presenting cells and appears to be co-expressed with major histocompatibility complex class II molecules. Eur. J. Immunol. 23 (1993) 2358-2364
11. Harigae H., Takahashi S., Suwabe N., Ohtsu H., Gu L., Yang Z., Tsai F.Y., Kitamura Y., Engel J.D., and Yamamoto M. Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells. Genes Cells 3 (1998) 39-50
12. Hauber H.P., Bergeron C., and Hamid Q. IL-9 in allergic inflammation. Int. Arch. Allergy Immunol. 134 (2004) 79-87
13. Henkel G., and Brown M.A. PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 7737-7741
14. Ho I.C., and Glimcher L.H. Transcription: tantalizing times for T cells. Cell 109 Suppl. (2002) S109-S120
15. Houssiau F.A., Schandene L., Stevens M., Cambiaso C., Goldman M., Van Snick J., and Renauld J.C. A cascade of cytokines is responsible for IL-9 expression in human T cells. Involvement of IL-2, IL-4, and IL-10. J. Immunol. 154 (1995) 2624-2630
16. Hultner L., Kolsch S., Stassen M., Kaspers U., Kremer J.P., Mailhammer R., Moeller J., Broszeit H., and Schmitt E. In activated mast cells, IL-1 up-regulates the production of several Th2-related cytokines including IL-9. J. Immunol. 164 (2000) 5556-5563
17. Hultner L., Moeller J., Schmitt E., Jager G., Reisbach G., Ring J., and Dormer P. Thiol-sensitive mast cell lines derived from mouse bone marrow respond to a mast cell growth-enhancing activity different from both IL-3 and IL-4. J. Immunol. 142 (1989) 3440-3446
18. Hung H.L., Lau J., Kim A.Y., Weiss M.J., and Blobel G.A. CREB-binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites. Mol. Cell Biol. 19 (1999) 3496-3505
19. Jippo T., Mizuno H., Xu Z., Nomura S., Yamamoto M., and Kitamura Y. Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization. Blood 87 (1996) 993-998
20. Leo O., Foo M., Sachs D.H., Samelson L.E., and Bluestone J.A. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc. Natl. Acad. Sci. U.S.A. 84 (1987) 1374-1378
21. Maeda K., Nishiyama C., Tokura T., Akizawa Y., Nishiyama M., Ogawa H., Okumura K., and Ra C. Regulation of cell type-specific mouse Fc epsilon RI beta-chain gene expression by GATA-1 via four GATA motifs in the promoter. J. Immunol. 170 (2003) 334-340
22. Martin D.I., Zon L.I., Mutter G., and Orkin S.H. Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages. Nature 344 (1990) 444-447
23. Masuda A., Yoshikai Y., Kume H., and Matsuguchi T. The interaction between GATA proteins and activator protein-1 promotes the transcription of IL-13 in mast cells. J. Immunol. 173 (2004) 5564-5573
24. Mazurek N., Schindler H., Schurholz T., and Pecht I. The cromolyn binding protein constitutes the Ca2+ channel of basophils opening upon immunological stimulus. Proc. Natl. Acad. Sci. U.S.A. 81 (1984) 6841-6845
25. Migliaccio A.R., Rana R.A., Sanchez M., Lorenzini R., Centurione L., Bianchi L., Vannucchi A.M., Migliaccio G., and Orkin S.H. GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant. J. Exp. Med. 197 (2003) 281-296
26. Moeller J., Hultner L., Schmitt E., and Dormer P. Partial purification of a mast cell growth-enhancing activity and its separation from IL-3 and IL-4. J. Immunol. 142 (1989) 3447-3451
27. Nicolaides N.C., Holroyd K.J., Ewart S.L., Eleff S.M., Kiser M.B., Dragwa C.R., Sullivan C.D., Grasso L., Zhang L.Y., Messler C.J., Zhou T., Kleeberger S.R., Buetow K.H., and Levitt R.C. Interleukin 9: a candidate gene for asthma. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 13175-13180
28. Nishiyama C., Ito T., Nishiyama M., Masaki S., Maeda K., Nakano N., Ng W., Fukuyama K., Yamamoto M., Okumura K., and Ogawa H. GATA-1 is required for expression of Fc{epsilon}RI on mast cells: analysis of mast cells derived from GATA-1 knockdown mouse bone marrow. Int. Immunol. 17 (2005) 847-856
29. Nishiyama C., Yokota T., Okumura K., and Ra C. The transcription factors Elf-1 and GATA-1 bind to cell-specific enhancer elements of human high-affinity IgE receptor alpha-chain gene. J. Immunol. 163 (1999) 623-630
30. Partington G.A., and Patient R.K. Phosphorylation of GATA-1 increases its DNA-binding affinity and is correlated with induction of human K562 erythroleukaemia cells. Nucleic Acids Res. 27 (1999) 1168-1175
31. Reisbach G., Bartke I., Kempkes B., Kostka G., Ellwart J., Birner A., Thalmeier K., Mailhammer R., Bornkamm G.W., and Ullrich A. Characterization of hemopoietic cell populations from human cord blood expressing c-kit. Exp. Hematol. 21 (1993) 74-79
32. Renauld J.C. New insights into the role of cytokines in asthma. J. Clin. Pathol. 54 (2001) 577-589
33. Renauld J.C., Goethals A., Houssiau F., Merz H., Van Roost E., and Van Snick J. Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene. J. Immunol. 144 (1990) 4235-4241
34. Schmitt E., Beuscher H.U., Huels C., Monteyne P., van Brandwijk R., Van Snick J., and Ruede E. IL-1 serves as a secondary signal for IL-9 expression. J. Immunol. 147 (1991) 3848-3854
35. Schmitt E., Germann T., Goedert S., Hoehn P., Huels C., Koelsch S., Kuhn R., Muller W., Palm N., and Rude E. IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma. J. Immunol. 153 (1994) 3989-3996
36. Schmitt E., van Brandwijk R., Van Snick J., Siebold B., and Rude E. TCGF III/P40 is produced by naive murine CD4+ T cells but is not a general T cell growth factor. Eur. J. Immunol. 19 (1989) 2167-2170
37. Smith V.M., Lee P.P., Szychowski S., and Winoto A. GATA-3 dominant negative mutant. Functional redundancy of the T cell receptor alpha and beta enhancers. J. Biol. Chem. 270 (1995) 1515-1520
38. Soutoglou E., and Talianidis I. Coordination of PIC assembly and chromatin remodeling during differentiation-induced gene activation. Science 295 (2002) 1901-1904
39. Stassen M., Arnold M., Hultner L., Muller C., Neudorfl C., Reineke T., and Schmitt E. Murine bone marrow-derived mast cells as potent producers of IL-9: costimulatory function of IL-10 and kit ligand in the presence of IL-1. J. Immunol. 164 (2000) 5549-5555
40. Stassen M., Jonuleit H., Muller C., Klein M., Richter C., Bopp T., Schmitt S., and Schmitt E. Differential regulatory capacity of CD25+ T regulatory cells and preactivated CD25+ T regulatory cells on development, functional activation, and proliferation of Th2 cells. J. Immunol. 173 (2004) 267-274
41. Stassen M., Muller C., Arnold M., Hultner L., Klein-Hessling S., Neudorfl C., Reineke T., Serfling E., and Schmitt E. IL-9 and IL-13 production by activated mast cells is strongly enhanced in the presence of lipopolysaccharide: NF-kappa B is decisively involved in the expression of IL-9. J. Immunol. 166 (2001) 4391-4398
42. Tang X.B., Liu D.P., and Liang C.C. Regulation of the transcription factor GATA-1 at the gene and protein level. Cell Mol. Life Sci. 58 (2001) 2008-2017
43. Temann U.A., Geba G.P., Rankin J.A., and Flavell R.A. Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J. Exp. Med. 188 (1998) 1307-1320
44. Tsai F.Y., and Orkin S.H. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood 89 (1997) 3636-3643
45. Uyttenhove C., Simpson R.J., and Van Snick J. Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 6934-6938
46. Yamagata T., Mitani K., Oda H., Suzuki T., Honda H., Asai T., Maki K., Nakamoto T., and Hirai H. Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs. EMBO J. 19 (2000) 4676-4687
47. Zon L.I., Gurish M.F., Stevens R.L., Mather C., Reynolds D.S., Austen K.F., and Orkin S.H. GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene. J. Biol. Chem. 266 (1991) 22948-22953