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Volumn 10, Issue 10, 2010, Pages 683-687

Cellular sources and immune functions of interleukin-9

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; INTERLEUKIN 9 RECEPTOR; JANUS KINASE 1; JANUS KINASE 3; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN;

EID: 77957228169     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/nri2848     Document Type: Review
Times cited : (257)

References (48)
  • 1
    • 0026683347 scopus 로고
    • Expression cloning of the murine and human interleukin 9 receptor cDNAs
    • Renauld, J. C. et al. Expression cloning of the murine and human interleukin 9 receptor cDNAs. Proc. Natl Acad. Sci. USA 89, 5690-5694 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 5690-5694
    • Renauld, J.C.1
  • 2
    • 0032502354 scopus 로고    scopus 로고
    • Heteromerization of the γ(c) chain with the interleukin-9 receptor subunit leads to STAT activation and prevention of apoptosis
    • DOI 10.1074/jbc.273.15.9255
    • Bauer, J. H., Liu, K. D., You, Y., Lai, S. Y. and Goldsmith, M. A. Heteromerization of the β chain with the interleukin-9 receptor α subunit leads to STAT activation and prevention of apoptosis. J. Biol. Chem. 273, 9255-9260 (1998). (Pubitemid 28176218)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.15 , pp. 9255-9260
    • Bauert, J.H.1    Lui, K.D.2    You, Y.3    Lai, S.Y.4    Goldsmith, M.A.5
  • 3
    • 0029785080 scopus 로고    scopus 로고
    • A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9
    • Demoulin, J. B. et al. A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9. Mol. Cell Biol. 16, 4710-4716 (1996).
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4710-4716
    • Demoulin, J.B.1
  • 4
    • 0033520477 scopus 로고    scopus 로고
    • Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9
    • Demoulin, J. B., Van Roost, E., Stevens, M., Groner, B. and Renauld, J. C. Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9. J. Biol. Chem. 274, 25855-25861 (1999). (Pubitemid 129530765)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.36 , pp. 25855-25861
    • Demoulin, J.-B.1    Van Roost, E.2    Stevens, M.3    Groner, B.4    Renauld, J.-C.5
  • 5
    • 0027717408 scopus 로고
    • Differential regulation of IL-9-expression after infection with Leishmania major in susceptible and resistant mice
    • Gessner, A., Blum, H. and Rollinghoff, M. Differential regulation of IL-9-expression after infection with Leishmania major in susceptible and resistant mice. Immunobiology 189, 419-435 (1993). (Pubitemid 24008832)
    • (1993) Immunobiology , vol.189 , Issue.5 , pp. 419-435
    • Gessner, A.1    Blum, H.2    Rollinghoff, M.3
  • 6
    • 77952584843 scopus 로고    scopus 로고
    • The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation
    • Chang, H. C. et al. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nature Immunol. 11, 527-534 (2010).
    • (2010) Nature Immunol. , vol.11 , pp. 527-534
    • Chang, H.C.1
  • 7
    • 56349093347 scopus 로고    scopus 로고
    • IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3- effector T cells
    • Dardalhon, V. et al. IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3- effector T cells. Nature Immunol. 9, 1347-1355 (2008).
    • (2008) Nature Immunol. , vol.9 , pp. 1347-1355
    • Dardalhon, V.1
  • 8
    • 56349154943 scopus 로고    scopus 로고
    • Transforming growth factor-β reprograms the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
    • Veldhoen, M. et al. Transforming growth factor-? reprograms the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nature Immunol. 9, 1341-1346 (2008).
    • (2008) Nature Immunol. , vol.9 , pp. 1341-1346
    • Veldhoen, M.1
  • 9
    • 77955902281 scopus 로고    scopus 로고
    • Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
    • 29 Jul 2010 (doi:10.1016/j.immuni.2010.07.014)
    • Staudt, V. et al. Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 29 Jul 2010 (doi:10.1016/ j.immuni.2010.07.014).
    • Immunity
    • Staudt, V.1
  • 15
    • 77955658181 scopus 로고    scopus 로고
    • Regulation of human Th9 differentiation by type i interferons and IL-21
    • Wong, M. T. et al. Regulation of human Th9 differentiation by type I interferons and IL-21. Immunol. Cell Biol. 88, 624-631(2010).
    • (2010) Immunol. Cell Biol. , vol.88 , pp. 624-631
    • Wong, M.T.1
  • 16
    • 77956220086 scopus 로고    scopus 로고
    • TGF-β Induces IL-9 production from human Th17 cells
    • Beriou, G. et al. TGF-β Induces IL-9 production from human Th17 cells. J. Immunol. 185, 46-54 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 46-54
    • Beriou, G.1
  • 18
    • 68149179251 scopus 로고    scopus 로고
    • IL-9 as a mediator of Th17-driven inflammatory disease
    • Nowak, E. C. et al. IL-9 as a mediator of Th17-driven inflammatory disease. J. Exp. Med. 206, 1653-1660 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 1653-1660
    • Nowak, E.C.1
  • 19
    • 69149107148 scopus 로고    scopus 로고
    • IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells
    • Elyaman, W. et al. IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc. Natl Acad. Sci. USA 106, 12885-12890 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 12885-12890
    • Elyaman, W.1
  • 20
    • 33748320914 scopus 로고    scopus 로고
    • Mast cells are essential intermediaries in regulatory T-cell tolerance
    • Lu, L. F. et al. Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature 442, 997-1002 (2006).
    • (2006) Nature , vol.442 , pp. 997-1002
    • Lu, L.F.1
  • 21
    • 33646596928 scopus 로고    scopus 로고
    • Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE
    • Liu, Y., Teige, I., Birnir, B. and Issazadeh-Navikas, S. Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE. Nature Med. 12, 518-525 (2006).
    • (2006) Nature Med. , vol.12 , pp. 518-525
    • Liu, Y.1    Teige, I.2    Birnir, B.3    Issazadeh-Navikas, S.4
  • 22
    • 55549084247 scopus 로고    scopus 로고
    • Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi cells
    • Hill, J. A. et al. Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi cells. Immunity 29, 758-770 (2008).
    • (2008) Immunity , vol.29 , pp. 758-770
    • Hill, J.A.1
  • 23
    • 0034082119 scopus 로고    scopus 로고
    • Murine bone marrow-derived mast cells as potent producers of IL-9: Costimulatory function of IL-10 and kit ligand in the presence of IL-1
    • Stassen, M. et al. Murine bone marrow-derived mast cells as potent producers of IL-9: costimulatory function of IL-10 and kit ligand in the presence of IL-1. J. Immunol. 164, 5549-5555 (2000). (Pubitemid 30389793)
    • (2000) Journal of Immunology , vol.164 , Issue.11 , pp. 5549-5555
    • Stassen, M.1    Arnold, M.2    Hultner, L.3    Muller, C.4    Neudorfl, C.5    Reineke, T.6    Schmitt, E.7
  • 24
    • 2342598346 scopus 로고    scopus 로고
    • IL-9 increases the expression of several cytokines in activated mast cells, while the IL-9-induced IL-9 production is inhibited in mast cells of histamine-free transgenic mice
    • DOI 10.1016/j.cyto.2004.01.006, PII S1043466604000468
    • Wiener, Z., Falus, A. and Toth, S. IL-9 increases the expression of several cytokines in activated mast cells, while the IL-9-induced IL-9 production is inhibited in mast cells of histamine-free transgenic mice. Cytokine 26, 122-130 (2004). (Pubitemid 38596922)
    • (2004) Cytokine , vol.26 , Issue.3 , pp. 122-130
    • Wiener, Z.1    Falus, A.2    Toth, S.3
  • 25
    • 0034663813 scopus 로고    scopus 로고
    • Cytokine production and killer activity of NK/T-NK cells derived with IL-2, IL-15, or the combination of IL-12 and IL-18
    • Lauwerys, B. R., Garot, N., Renauld, J. C. and Houssiau, F. A. Cytokine production and killer activity of NK/T-NK cells derived with IL-2, IL-15, or the combination of IL-12 and IL-18. J. Immunol. 165, 1847-1853 (2000). (Pubitemid 30643135)
    • (2000) Journal of Immunology , vol.165 , Issue.4 , pp. 1847-1853
    • Lauwerys, B.R.1    Garot, N.2    Renauld, J.-C.3    Houssiau, F.A.4
  • 26
    • 75149168383 scopus 로고    scopus 로고
    • Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells
    • Jones, T. G. et al. Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells. J. Immunol. 183, 5251-5260 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 5251-5260
    • Jones, T.G.1
  • 28
    • 0025200126 scopus 로고
    • Cloning and expression of a cDNA for the human homolog of mouse T cell and mast cell growth factor P40
    • Renauld, J. C., Goethals, A., Houssiau, F., Van Roost, E. and Van Snick, J. Cloning and expression of a cDNA for the human homolog of mouse T cell and mast cell growth factor P40. Cytokine 2, 9-12 (1990).
    • (1990) Cytokine , vol.2 , pp. 9-12
    • Renauld, J.C.1    Goethals, A.2    Houssiau, F.3    Van Roost, E.4    Van Snick, J.5
  • 29
    • 0033696860 scopus 로고    scopus 로고
    • IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development
    • Townsend, J. M. et al. IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development. Immunity 13, 573-583 (2000).
    • (2000) Immunity , vol.13 , pp. 573-583
    • Townsend, J.M.1
  • 30
    • 11844254514 scopus 로고    scopus 로고
    • 1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice
    • DOI 10.1016/j.nbd.2004.09.018, PII S0969996104002323
    • Mesples, B., Fontaine, R. H., Lelievre, V., Launay, J. M. and Gressens, P. Neuronal TGF-?1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice. Neurobiol. Dis. 18, 193-205 (2005). (Pubitemid 40092909)
    • (2005) Neurobiology of Disease , vol.18 , Issue.1 , pp. 193-205
    • Mesples, B.1    Fontaine, R.H.2    Lelievre, V.3    Launay, J.-M.4    Gressens, P.5
  • 31
    • 0033562582 scopus 로고    scopus 로고
    • A novel function for transforming growth factor-β1: Upregulation of the expression and the IgE-independent extracellular release of a mucosal mast cell granule-specific β-chymase, mouse mast cell protease-1
    • Miller, H. R., Wright, S. H., Knight, P. A. and Thornton, E. M. A novel function for transforming growth factor-β1: upregulation of the expression and the IgE-independent extracellular release of a mucosal mast cell granule-specific β-chymase, mouse mast cell protease-1. Blood 93, 3473-3486 (1999).
    • (1999) Blood , vol.93 , pp. 3473-3486
    • Miller, H.R.1    Wright, S.H.2    Knight, P.A.3    Thornton, E.M.4
  • 32
    • 65249123621 scopus 로고    scopus 로고
    • IL-9 promotes IL-13-dependent paneth cell hyperplasia and up-regulation of innate immunity mediators in intestinal mucosa
    • Steenwinckel, V. et al. IL-9 promotes IL-13-dependent paneth cell hyperplasia and up-regulation of innate immunity mediators in intestinal mucosa. J. Immunol. 182, 4737-4743 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 4737-4743
    • Steenwinckel, V.1
  • 34
    • 0036141448 scopus 로고    scopus 로고
    • Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology
    • DOI 10.1172/JCI200213696
    • Temann, U. A., Ray, P. and Flavell, R. A. Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology. J. Clin. Invest. 109, 29-39 (2002). (Pubitemid 34052539)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.1 , pp. 29-39
    • Temann, U.-A.1    Ray, P.2    Flavell, R.A.3
  • 39
    • 37849013225 scopus 로고    scopus 로고
    • IL-9 is associated with an impaired Th1 immune response in patients with tuberculosis
    • Wu, B. et al. IL-9 is associated with an impaired Th1 immune response in patients with tuberculosis. Clin. Immunol. 126, 202-210 (2008).
    • (2008) Clin. Immunol. , vol.126 , pp. 202-210
    • Wu, B.1
  • 41
    • 75849157327 scopus 로고    scopus 로고
    • Differential roles for the IL-9/IL-9 receptor β-chain pathway in systemic and oral antigen-induced anaphylaxis
    • e462
    • Osterfeld, H. et al. Differential roles for the IL-9/IL-9 receptor β-chain pathway in systemic and oral antigen-induced anaphylaxis. J. Allergy Clin. Immunol. 125, 469-476, e462 (2010).
    • (2010) J. Allergy Clin. Immunol. , vol.125 , pp. 469-476
    • Osterfeld, H.1
  • 42
    • 77957230475 scopus 로고    scopus 로고
    • Neutralization of IL-9 amerliorates experimental autoimmune encephalomyelitis by decreasing the effector T cell population
    • 30 Aug 2010 (doi doi:10.4049/jimmunol.1000986)
    • Li, H. et al. Neutralization of IL-9 amerliorates experimental autoimmune encephalomyelitis by decreasing the effector T cell population. J. Immunol. 30 Aug 2010 (doi:10.4049/jimmunol.1000986).
    • J. Immunol.
    • Li, H.1
  • 43
    • 73349109145 scopus 로고    scopus 로고
    • Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
    • Jager, A., Dardalhon, V., Sobel, R. A., Bettelli, E. and Kuchroo, V. K. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J. Immunol. 183, 7169-7177 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 7169-7177
    • Jager, A.1    Dardalhon, V.2    Sobel, R.A.3    Bettelli, E.4    Kuchroo, V.K.5
  • 44
    • 77956647977 scopus 로고    scopus 로고
    • Oral tolerance reduces Th17 cells as well as the overall inflammation in the central nervous system of EAE mice
    • 25 Jun 2010 (doi doi:10.1016/j.neuroim.2010.06.002)
    • Peron, J. P. et al. Oral tolerance reduces Th17 cells as well as the overall inflammation in the central nervous system of EAE mice. J. Neuroimmunol. 25 Jun 2010 (doi:10.1016/j.neuroim.2010.06.002).
    • J. Neuroimmunol.
    • Peron, J.P.1
  • 45
    • 0242500350 scopus 로고    scopus 로고
    • Modulation of intestinal muscle contraction by interleukin-9 (IL-9) or IL-9 neutralization: Correlation with worm expulsion in murine nematode infections
    • Khan, W. I. et al. Modulation of intestinal muscle contraction by interleukin-9 (IL-9) or IL-9 neutralization: correlation with worm expulsion in murine nematode infections. Infect. Immun. 71, 2430-2438 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 2430-2438
    • Khan, W.I.1
  • 46
    • 42249098670 scopus 로고    scopus 로고
    • IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity
    • Forbes, E. E. et al. IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. J. Exp. Med. 205, 897-913 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 897-913
    • Forbes, E.E.1
  • 48
    • 70349212509 scopus 로고    scopus 로고
    • Mast cell degranulation breaks peripheral tolerance
    • de Vries, V. C. et al. Mast cell degranulation breaks peripheral tolerance. Am. J. Transplant 9, 2270-2280 (2009).
    • (2009) Am. J. Transplant , vol.9 , pp. 2270-2280
    • De Vries, V.C.1


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