Use of STAT1 inhibitors in the treatment of brain I/R injury and neurodegenerative diseases

Central Nervous System Agents in Medicinal Chemistry

Volumn 11, Issue 1, 2011, Pages 2-7

  Ebner, F H ^a   Darra, E ^a   Mariotto, S ^a   Suzuki, H ^a   Cavalieri, E ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Ageing; Anti inflammatory drug; Arbutus unedo; Blood brain barrier; Brain; Endothelial NOS; Epigallocatechin 3 gallate; Flavonoids; Hyperfptin; Inducible NOS; Inflammation; Inhibitor; Injury; Ischemia; JAK STAT pathway; Microglia; Neurodegenerative diseases; Neuronal NOS; NF kappaB; Nitric oxide (NO); NO synthase (NOS); Pro and anti inflammatory cytokines; Reperfusion; STAT1; Stroke

Indexed keywords

EPIGALLOCATECHIN GALLATE; ERYTHROPOIETIN; GAMMA INTERFERON; GINKGO BILOBA EXTRACT; GREEN TEA EXTRACT; HYPERFORIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 4; JANUS KINASE; NEURONAL NITRIC OXIDE SYNTHASE; STAT1 PROTEIN; STAT2 PROTEIN; STAT3 PROTEIN; STAT4 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; STAT6 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; BICYCLO COMPOUND; CATECHIN; NEUROPROTECTIVE AGENT; PHLOROGLUCINOL; TERPENE;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CELL DEATH; DEGENERATIVE DISEASE; DOWN REGULATION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; NONHUMAN; PANCREAS ISLET BETA CELL; REPERFUSION INJURY; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; NEURODEGENERATIVE DISEASES; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; BICYCLO COMPOUNDS; BRAIN; CATECHIN; HUMANS; JANUS KINASES; MOLECULAR STRUCTURE; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; PHLOROGLUCINOL; REPERFUSION INJURY; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TERPENES;

EID: 79953034160     PISSN: 18715249     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152411794961077     Document Type: Article

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