-
1
-
-
0035746917
-
Expression of a dominant negative inhibitor of NF-κB protects MIN6 beta-cells from cytokine-induced apoptosis
-
Baker M.S., Chen X., Cao X.C., and Kaufman D.B. Expression of a dominant negative inhibitor of NF-κB protects MIN6 beta-cells from cytokine-induced apoptosis. J. Surg. Res. 97 (2001) 117-122
-
(2001)
J. Surg. Res.
, vol.97
, pp. 117-122
-
-
Baker, M.S.1
Chen, X.2
Cao, X.C.3
Kaufman, D.B.4
-
2
-
-
4644233237
-
Response of human islets to isolation stress and the effect of antioxidant treatment
-
Bottino R., Balamurugan A.N., Tse H., Thirunavukkarasu C., Ge X., Profozich J., et al. Response of human islets to isolation stress and the effect of antioxidant treatment. Diabetes 53 (2004) 2559-2568
-
(2004)
Diabetes
, vol.53
, pp. 2559-2568
-
-
Bottino, R.1
Balamurugan, A.N.2
Tse, H.3
Thirunavukkarasu, C.4
Ge, X.5
Profozich, J.6
-
3
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
4
-
-
0037219411
-
Beta-cell deficit and increased cell apoptosis in humans with type 2 diabetes
-
Butler A.E., Janson J., Bonner-Weir S., Ritzel R., Rizza R.A., and Butler P.C. Beta-cell deficit and increased cell apoptosis in humans with type 2 diabetes. Diabetes 52 (2003) 102-110
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
5
-
-
0035966006
-
A comprehensive analysis of cytokine-induced and nuclear factor-kB-dependent genes in primary rat pancreatic beta-cells
-
Cardozo A.K., Heimberg H., Heremans Y., Leeman R., Kutlu B., Kruhoffer M., et al. A comprehensive analysis of cytokine-induced and nuclear factor-kB-dependent genes in primary rat pancreatic beta-cells. J. Biol. Chem. 276 (2001) 48879-48886
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48879-48886
-
-
Cardozo, A.K.1
Heimberg, H.2
Heremans, Y.3
Leeman, R.4
Kutlu, B.5
Kruhoffer, M.6
-
6
-
-
39149102105
-
A neuroprotective herbal mixture inhibits caspase-3-independent apoptosis in retinal ganglion cells
-
Cheung Z.H., Leung M.C.P., Yip H.K., Wu W., Siu F.K.W., and So K.-F. A neuroprotective herbal mixture inhibits caspase-3-independent apoptosis in retinal ganglion cells. Cell. Mol. Neurobiol. 28 (2008) 137-155
-
(2008)
Cell. Mol. Neurobiol.
, vol.28
, pp. 137-155
-
-
Cheung, Z.H.1
Leung, M.C.P.2
Yip, H.K.3
Wu, W.4
Siu, F.K.W.5
So, K.-F.6
-
7
-
-
0035656193
-
Gamma-interferon signalling in pancreatic beta-cells is persistent but can be terminated by overexpression of suppressor of cytokine signalling-1
-
Chong M.M.W., Thomas H.E., and Kay T.W.H. Gamma-interferon signalling in pancreatic beta-cells is persistent but can be terminated by overexpression of suppressor of cytokine signalling-1. Diabetes 50 (2001) 2744-2751
-
(2001)
Diabetes
, vol.50
, pp. 2744-2751
-
-
Chong, M.M.W.1
Thomas, H.E.2
Kay, T.W.H.3
-
8
-
-
0035854646
-
SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma
-
Cottet S., Dupraz P., Hamburger F., Dolci W., Jaquet M., and Thorens B. SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma. J. Biol. Chem. 276 (2001) 25862-25870
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25862-25870
-
-
Cottet, S.1
Dupraz, P.2
Hamburger, F.3
Dolci, W.4
Jaquet, M.5
Thorens, B.6
-
9
-
-
33751503444
-
Protective effect of Hypericum perforatum in zymosan-induced multiple organ dysfunction syndrome: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity
-
Di Paola R., Mazzon E., Muià C., Crisafulli C., Genovese T., Di Bella P., et al. Protective effect of Hypericum perforatum in zymosan-induced multiple organ dysfunction syndrome: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity. Nitric Oxide 16 (2007) 118-130
-
(2007)
Nitric Oxide
, vol.16
, pp. 118-130
-
-
Di Paola, R.1
Mazzon, E.2
Muià, C.3
Crisafulli, C.4
Genovese, T.5
Di Bella, P.6
-
10
-
-
0034532379
-
Dominant negative MyD88 proteins inhibit interleukin-1β/interferon-gamma-mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells
-
Dupraz P., Cottet S., Hamburger F., Dolci W., Felley-Bosco E., and Thorens B. Dominant negative MyD88 proteins inhibit interleukin-1β/interferon-gamma-mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells. J. Biol. Chem. 275 (2000) 37672-37678
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 37672-37678
-
-
Dupraz, P.1
Cottet, S.2
Hamburger, F.3
Dolci, W.4
Felley-Bosco, E.5
Thorens, B.6
-
11
-
-
0035668779
-
A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis
-
Eizirik D.L., and Mandrup-Poulsen T. A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 44 (2001) 2115-2133
-
(2001)
Diabetologia
, vol.44
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
12
-
-
0035902480
-
Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-κB
-
Ganster R.W., Taylor B.S., Shao L., and Geller D.A. Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-κB. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 8638-8643
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 8638-8643
-
-
Ganster, R.W.1
Taylor, B.S.2
Shao, L.3
Geller, D.A.4
-
13
-
-
33646810510
-
Hypericum perforatum attenuates the development of cerulein-induced acute pancreatitis in mice
-
Genovese T., Mazzon E., Di Paola R., Muià C., Crisafulli C., Menegazzi M., et al. Hypericum perforatum attenuates the development of cerulein-induced acute pancreatitis in mice. Shock 25 (2006) 161-167
-
(2006)
Shock
, vol.25
, pp. 161-167
-
-
Genovese, T.1
Mazzon, E.2
Di Paola, R.3
Muià, C.4
Crisafulli, C.5
Menegazzi, M.6
-
14
-
-
0034711250
-
Protection of human islets from the effects of interleukin-1β by adenoviral gene transfer of an IκB repressor
-
Giannoukakis N., Rudert W.A., Trucco M., and Robbins P.D. Protection of human islets from the effects of interleukin-1β by adenoviral gene transfer of an IκB repressor. J. Biol. Chem. 275 (2000) 36509-36513
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36509-36513
-
-
Giannoukakis, N.1
Rudert, W.A.2
Trucco, M.3
Robbins, P.D.4
-
15
-
-
0033595892
-
The Rel/NF-κB signal transduction pathway: Introduction
-
Gilmore T.D. The Rel/NF-κB signal transduction pathway: Introduction. Oncogene 18 (1999) 6842-6844
-
(1999)
Oncogene
, vol.18
, pp. 6842-6844
-
-
Gilmore, T.D.1
-
16
-
-
0035106685
-
St. John's wort: A review of the current pharmacological, toxicological and clinical literature
-
Greeson J.M., Sanford B., and Monti D.A. St. John's wort: A review of the current pharmacological, toxicological and clinical literature. Psychopharmacology (Berl.) 153 (2001) 402-414
-
(2001)
Psychopharmacology (Berl.)
, vol.153
, pp. 402-414
-
-
Greeson, J.M.1
Sanford, B.2
Monti, D.A.3
-
17
-
-
23644437526
-
Disruption of the γ-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells
-
Gysemans C.A., Ladrière L., Callewaert H., Rasschaert J., Flamez D., Levy D.E., et al. Disruption of the γ-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells. Diabetes 54 (2005) 2396-2403
-
(2005)
Diabetes
, vol.54
, pp. 2396-2403
-
-
Gysemans, C.A.1
Ladrière, L.2
Callewaert, H.3
Rasschaert, J.4
Flamez, D.5
Levy, D.E.6
-
18
-
-
0032832969
-
Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans
-
Heitmeier M.R., Scarim A.L., and Corbett J.A. Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans. J. Biol. Chem. 274 (1999) 29266-29273
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29266-29273
-
-
Heitmeier, M.R.1
Scarim, A.L.2
Corbett, J.A.3
-
19
-
-
0037482859
-
Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines
-
Hostanska K., Reichling J., Bommer S., Weber M., and Saller R. Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines. Eur. J. Pharm. Biopharm. 56 (2003) 121-132
-
(2003)
Eur. J. Pharm. Biopharm.
, vol.56
, pp. 121-132
-
-
Hostanska, K.1
Reichling, J.2
Bommer, S.3
Weber, M.4
Saller, R.5
-
20
-
-
0034891508
-
Hypericum perforatum: A review of clinical studies
-
Kasper S. Hypericum perforatum: A review of clinical studies. Pharmacopsychiatry 1 (2001) S51-S55
-
(2001)
Pharmacopsychiatry
, vol.1
-
-
Kasper, S.1
-
21
-
-
0033598839
-
Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway
-
Kovarik P., Stoiber D., Eyers P.A., Menghini R., Neininger A., Gaestel M., et al. Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 13956-13961
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13956-13961
-
-
Kovarik, P.1
Stoiber, D.2
Eyers, P.A.3
Menghini, R.4
Neininger, A.5
Gaestel, M.6
-
22
-
-
0242363618
-
Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells
-
Kutlu B., Cardozo A.K., Darville M.I., Kruhoffer M., Magnusson N., Orntoft T., et al. Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells. Diabetes 52 (2003) 2701-2719
-
(2003)
Diabetes
, vol.52
, pp. 2701-2719
-
-
Kutlu, B.1
Cardozo, A.K.2
Darville, M.I.3
Kruhoffer, M.4
Magnusson, N.5
Orntoft, T.6
-
23
-
-
0036315888
-
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: Evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated
-
Lupi R., Dotta F., Marselli L., Del Guerra S., Masini M., Santangelo C., et al. Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: Evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated. Diabetes 51 (2002) 1437-1442
-
(2002)
Diabetes
, vol.51
, pp. 1437-1442
-
-
Lupi, R.1
Dotta, F.2
Marselli, L.3
Del Guerra, S.4
Masini, M.5
Santangelo, C.6
-
24
-
-
0036738398
-
Glucose induced beta cell production of IL-1β contributes to glucose toxicity in human pancreatic islets
-
Maedler K., Sergeev P., Ris F., Oberholzer J., Joller-Jemelka H.I., Spinas G.A., et al. Glucose induced beta cell production of IL-1β contributes to glucose toxicity in human pancreatic islets. J. Clin. Invest. 110 (2002) 851-860
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 851-860
-
-
Maedler, K.1
Sergeev, P.2
Ris, F.3
Oberholzer, J.4
Joller-Jemelka, H.I.5
Spinas, G.A.6
-
25
-
-
0442305381
-
Apoptotic signal transduction pathways in diabetes
-
Mandrup-Poulsen T. Apoptotic signal transduction pathways in diabetes. Biochem. Pharmacol. 66 (2003) 1433-1440
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 1433-1440
-
-
Mandrup-Poulsen, T.1
-
26
-
-
0035856952
-
Beta-cell death during progression to diabetes
-
Mathis D., Vence L., and Benoist C. Beta-cell death during progression to diabetes. Nature 414 (2001) 792-798
-
(2001)
Nature
, vol.414
, pp. 792-798
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
27
-
-
0035946507
-
Metabolic and functional studies on isolated islets in a new rat model of type 2 diabetes
-
Novelli M., Fabregat M.E., Fernandez-Alvarez J., Gomis R., and Masiello P. Metabolic and functional studies on isolated islets in a new rat model of type 2 diabetes. Mol. Cell. Endocrinol. 175 (2001) 57-66
-
(2001)
Mol. Cell. Endocrinol.
, vol.175
, pp. 57-66
-
-
Novelli, M.1
Fabregat, M.E.2
Fernandez-Alvarez, J.3
Gomis, R.4
Masiello, P.5
-
28
-
-
0342742310
-
Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B
-
Osborn L., Kunkel S., and Nabel G.J. Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 2336-2340
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 2336-2340
-
-
Osborn, L.1
Kunkel, S.2
Nabel, G.J.3
-
29
-
-
0033168661
-
Interation of nuclear protein CBF1 with the κB site of the IL-6 promoter
-
Palmieri M., Sasso M.P., Monese R., Merola M., Faggioli L., Tovey M., et al. Interation of nuclear protein CBF1 with the κB site of the IL-6 promoter. Nucleic Acid Res. 27 (1999) 2785-2791
-
(1999)
Nucleic Acid Res.
, vol.27
, pp. 2785-2791
-
-
Palmieri, M.1
Sasso, M.P.2
Monese, R.3
Merola, M.4
Faggioli, L.5
Tovey, M.6
-
30
-
-
0033596121
-
Activators and target genes of Rel/NF-κB transcription factors
-
Path H.L. Activators and target genes of Rel/NF-κB transcription factors. Oncogene 18 (1999) 6853-6866
-
(1999)
Oncogene
, vol.18
, pp. 6853-6866
-
-
Path, H.L.1
-
31
-
-
0032727032
-
Signaling pathways activated by interferons
-
Platanias L.C., and Fish E.N. Signaling pathways activated by interferons. Exp. Hematol. 27 (1999) 1583-1592
-
(1999)
Exp. Hematol.
, vol.27
, pp. 1583-1592
-
-
Platanias, L.C.1
Fish, E.N.2
-
32
-
-
0034456628
-
Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhibitable pathway in rat insulin-producing cells
-
Saldeen J. Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhibitable pathway in rat insulin-producing cells. Endocrinology 141 (2000) 2003-2010
-
(2000)
Endocrinology
, vol.141
, pp. 2003-2010
-
-
Saldeen, J.1
-
33
-
-
0034658111
-
Pharmaceutical intervention in the JAK/STAT signaling pathway
-
Seidel H.M., Lamb P., and Rosen J. Pharmaceutical intervention in the JAK/STAT signaling pathway. Oncogene 19 (2000) 2645-2656
-
(2000)
Oncogene
, vol.19
, pp. 2645-2656
-
-
Seidel, H.M.1
Lamb, P.2
Rosen, J.3
-
34
-
-
0034036353
-
Synergistic activation of NF-κB and inducible isoform of nitric oxide synthase induction by interferon-gamma and tumor necrosis factor-alpha in INS-1 cells
-
Sekine N., Ishikawa T., Okazaki T., Hayashi M., Wollheim C.B., and Fujita T. Synergistic activation of NF-κB and inducible isoform of nitric oxide synthase induction by interferon-gamma and tumor necrosis factor-alpha in INS-1 cells. J. Cell. Physiol. 184 (2000) 46-57
-
(2000)
J. Cell. Physiol.
, vol.184
, pp. 46-57
-
-
Sekine, N.1
Ishikawa, T.2
Okazaki, T.3
Hayashi, M.4
Wollheim, C.B.5
Fujita, T.6
-
35
-
-
0034616164
-
Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis
-
Stephanou A., Brar B.K., Scarabelli T.M., Janassen A.K., Yellon D.M., Marber M.S., et al. Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis. J. Biol. Chem. 275 (2000) 10002-10008
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10002-10008
-
-
Stephanou, A.1
Brar, B.K.2
Scarabelli, T.M.3
Janassen, A.K.4
Yellon, D.M.5
Marber, M.S.6
-
36
-
-
0034746919
-
NF-κB: A key role in inflammatory diseases
-
Tak P.P., and Firestein G.S. NF-κB: A key role in inflammatory diseases. J. Clin. Invest. 107 (2001) 7-11
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 7-11
-
-
Tak, P.P.1
Firestein, G.S.2
-
37
-
-
0141742433
-
Anti-inflammatory actions of St. John's wort: Inhibition of human inducible nitric-oxide synthase expression by down-regulating signal transducer and activator of transcription-1alpha (STAT-1alpha) activation
-
Tedeschi E., Menegazzi M., Margotto D., Suzuki H., Forstermann U., and Kleinert H. Anti-inflammatory actions of St. John's wort: Inhibition of human inducible nitric-oxide synthase expression by down-regulating signal transducer and activator of transcription-1alpha (STAT-1alpha) activation. J. Pharmacol. Exp. Ther. 307 (2003) 254-261
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.307
, pp. 254-261
-
-
Tedeschi, E.1
Menegazzi, M.2
Margotto, D.3
Suzuki, H.4
Forstermann, U.5
Kleinert, H.6
-
38
-
-
0036068246
-
Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell nitric oxide production
-
Thomas H.E., Darwiche R., Corbett J.A., and Thomas W.H.K. Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell nitric oxide production. Diabetes 51 (2002) 311-316
-
(2002)
Diabetes
, vol.51
, pp. 311-316
-
-
Thomas, H.E.1
Darwiche, R.2
Corbett, J.A.3
Thomas, W.H.K.4
-
39
-
-
6944237757
-
Adipokines: Inflammation and the pleiotropic role of white adipose tissue
-
Trayhurn P., and Wood I.S. Adipokines: Inflammation and the pleiotropic role of white adipose tissue. Br. J. Nutr. 92 (2004) 347-355
-
(2004)
Br. J. Nutr.
, vol.92
, pp. 347-355
-
-
Trayhurn, P.1
Wood, I.S.2
-
40
-
-
0025639009
-
The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
-
Wagner B.J., Hayes T.E., Hoban C.J., and Cochran B.H. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J. 9 (1990) 4477-4484
-
(1990)
EMBO J.
, vol.9
, pp. 4477-4484
-
-
Wagner, B.J.1
Hayes, T.E.2
Hoban, C.J.3
Cochran, B.H.4
-
41
-
-
0035085242
-
Human islet cell transplantation-future prospects
-
White S.A., James R.F.L., Swift S.M., Kimber R.M., and Nicholson M.L. Human islet cell transplantation-future prospects. Diabet. Med. 18 (2001) 78-103
-
(2001)
Diabet. Med.
, vol.18
, pp. 78-103
-
-
White, S.A.1
James, R.F.L.2
Swift, S.M.3
Kimber, R.M.4
Nicholson, M.L.5
-
42
-
-
6344265234
-
Pioglitazone and sodium salicylate protect human beta-cells against apoptosis and impaired function induced by glucose and interleukin-1β
-
Zeender E., Maedler K., Bosco D., Berney T., Donath M.Y., and Halban P.A. Pioglitazone and sodium salicylate protect human beta-cells against apoptosis and impaired function induced by glucose and interleukin-1β. J. Clin. Endocrinol. Metab. 89 (2004) 5059-5066
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 5059-5066
-
-
Zeender, E.1
Maedler, K.2
Bosco, D.3
Berney, T.4
Donath, M.Y.5
Halban, P.A.6
|