메뉴 건너뛰기




Volumn 30, Issue 12, 2009, Pages 1924-1935

Interferon-γ-dependent cytotoxic activation of human astrocytes and astrocytoma cells

Author keywords

Astrocytes; Cytotoxicity; Interferon ; Interferon receptor; Neurodegenerative diseases

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 1BETA; JANUS KINASE; JANUS KINASE INHIBITOR; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; STAT PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 70349860184     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2008.02.019     Document Type: Article
Times cited : (83)

References (39)
  • 2
    • 18144435991 scopus 로고    scopus 로고
    • Immune and inflammatory responses in the CNS: modulation by astrocytes
    • Aschner M. Immune and inflammatory responses in the CNS: modulation by astrocytes. Toxicol. Lett. 102-103 (1998) 283-287
    • (1998) Toxicol. Lett. , vol.102-103 , pp. 283-287
    • Aschner, M.1
  • 3
    • 0030889207 scopus 로고    scopus 로고
    • The IFN gamma receptor: a paradigm for cytokine receptor signaling
    • Bach E.A., Aguet M., and Schreiber RD. The IFN gamma receptor: a paradigm for cytokine receptor signaling. Annu. Rev. Immunol. 5 (1997) 563-591
    • (1997) Annu. Rev. Immunol. , vol.5 , pp. 563-591
    • Bach, E.A.1    Aguet, M.2    Schreiber, RD.3
  • 4
    • 0035449358 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity
    • Bal-Price A., and Brown G.C. Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. J. Neurosci. 21 (2001) 6480-6491
    • (2001) J. Neurosci. , vol.21 , pp. 6480-6491
    • Bal-Price, A.1    Brown, G.C.2
  • 5
    • 0035157425 scopus 로고    scopus 로고
    • Glial cells as targets for cytotoxic immune mediators
    • Benn T., Halfpenny C., and Scolding N. Glial cells as targets for cytotoxic immune mediators. Glia 36 (2001) 200-211
    • (2001) Glia , vol.36 , pp. 200-211
    • Benn, T.1    Halfpenny, C.2    Scolding, N.3
  • 6
    • 0345580623 scopus 로고    scopus 로고
    • Cytokine actions in the central nervous system
    • Benveniste E.N. Cytokine actions in the central nervous system. Cytokine Growth Factor Rev. 9 (1998) 259-275
    • (1998) Cytokine Growth Factor Rev. , vol.9 , pp. 259-275
    • Benveniste, E.N.1
  • 7
    • 33847707328 scopus 로고    scopus 로고
    • Identification of soluble CD14 as an endogenous agonist for Toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins
    • Bsibsi M., Bajramovic J.J., Van Duijvenvoorden E., Persoon C., Ravid R., Van Noort J.M., and Vogt M.H. Identification of soluble CD14 as an endogenous agonist for Toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins. Glia 55 (2007) 473-482
    • (2007) Glia , vol.55 , pp. 473-482
    • Bsibsi, M.1    Bajramovic, J.J.2    Van Duijvenvoorden, E.3    Persoon, C.4    Ravid, R.5    Van Noort, J.M.6    Vogt, M.H.7
  • 9
    • 0030108525 scopus 로고    scopus 로고
    • Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
    • Chao C.C., Hu S., Sheng W.S., Bu D., Bukrinsky M.I., and Peterson P.K. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia 16 (1996) 276-284
    • (1996) Glia , vol.16 , pp. 276-284
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Bu, D.4    Bukrinsky, M.I.5    Peterson, P.K.6
  • 11
    • 0035153212 scopus 로고    scopus 로고
    • Immune function of astrocytes
    • Dong Y., and Benveniste E.N. Immune function of astrocytes. Glia 36 (2001) 180-190
    • (2001) Glia , vol.36 , pp. 180-190
    • Dong, Y.1    Benveniste, E.N.2
  • 12
    • 0033230204 scopus 로고    scopus 로고
    • Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha
    • Downen M., Amaral T.D., Hua L.L., Zhao M.L., and Lee S.C. Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha. Glia 28 (1999) 114-127
    • (1999) Glia , vol.28 , pp. 114-127
    • Downen, M.1    Amaral, T.D.2    Hua, L.L.3    Zhao, M.L.4    Lee, S.C.5
  • 13
    • 33847099936 scopus 로고    scopus 로고
    • Astrocytes are active players in cerebral innate immunity
    • Farina C., Aloisi F., and Meinl E. Astrocytes are active players in cerebral innate immunity. Trends Immunol. 28 (2007) 138-145
    • (2007) Trends Immunol. , vol.28 , pp. 138-145
    • Farina, C.1    Aloisi, F.2    Meinl, E.3
  • 14
    • 0028219965 scopus 로고
    • A novel member of the interferon receptor family complements functionality of the murine interferon γ receptor in human cells
    • Hemmi S., Bohni R., Stark G., Di Marco F., and Aguet M. A novel member of the interferon receptor family complements functionality of the murine interferon γ receptor in human cells. Cell 76 (1994) 803-810
    • (1994) Cell , vol.76 , pp. 803-810
    • Hemmi, S.1    Bohni, R.2    Stark, G.3    Di Marco, F.4    Aguet, M.5
  • 15
    • 0023772808 scopus 로고
    • Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue
    • Itagaki S., McGeer P.L., and Akiyama H. Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue. Neurosci. Lett. 91 (1988) 259-264
    • (1988) Neurosci. Lett. , vol.91 , pp. 259-264
    • Itagaki, S.1    McGeer, P.L.2    Akiyama, H.3
  • 16
    • 15744399836 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes
    • Jana M., Anderson J.A., Saha R.N., Liu X., and Pahan K. Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radic. Biol. Med. 38 (2005) 655-664
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 655-664
    • Jana, M.1    Anderson, J.A.2    Saha, R.N.3    Liu, X.4    Pahan, K.5
  • 17
    • 0037309385 scopus 로고    scopus 로고
    • Cytokines: powerful regulators of glial cell activation
    • John G.R., Lee S.C., and Brosnan C.F. Cytokines: powerful regulators of glial cell activation. Neuroscientist 9 (2003) 10-22
    • (2003) Neuroscientist , vol.9 , pp. 10-22
    • John, G.R.1    Lee, S.C.2    Brosnan, C.F.3
  • 18
    • 0026605961 scopus 로고
    • Immunologic reactions in amyotrophic lateral scelrosis brain and spinal cord
    • Kawamata T., Akiyama H., Yamada T., and McGeer P.L. Immunologic reactions in amyotrophic lateral scelrosis brain and spinal cord. Am. J. Pathol. 140 (1992) 691-707
    • (1992) Am. J. Pathol. , vol.140 , pp. 691-707
    • Kawamata, T.1    Akiyama, H.2    Yamada, T.3    McGeer, P.L.4
  • 19
    • 0037686180 scopus 로고    scopus 로고
    • Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAP
    • Klegeris A., and McGeer P.L. Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAP. J. Leukoc. Biol. 73 (2003) 369-378
    • (2003) J. Leukoc. Biol. , vol.73 , pp. 369-378
    • Klegeris, A.1    McGeer, P.L.2
  • 20
    • 13644255246 scopus 로고    scopus 로고
    • Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system
    • Klegeris A., Bissonnette C.J., and McGeer P.L. Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system. Neurobiol. Aging 26 (2005) 673-682
    • (2005) Neurobiol. Aging , vol.26 , pp. 673-682
    • Klegeris, A.1    Bissonnette, C.J.2    McGeer, P.L.3
  • 21
    • 34248400478 scopus 로고    scopus 로고
    • Therapeutic approaches to inflammation in neurodegenerative disease
    • Klegeris A., McGeer E.G., and McGeer P.L. Therapeutic approaches to inflammation in neurodegenerative disease. Curr. Opin. Neurol. 20 (2007) 351-357
    • (2007) Curr. Opin. Neurol. , vol.20 , pp. 351-357
    • Klegeris, A.1    McGeer, E.G.2    McGeer, P.L.3
  • 22
    • 0027298505 scopus 로고
    • Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta
    • Lee S.C., Liu W., Dickson D.W., Brosnan C.F., and Berman J.W. Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J. Immunol. 150 (1993) 2659-2667
    • (1993) J. Immunol. , vol.150 , pp. 2659-2667
    • Lee, S.C.1    Liu, W.2    Dickson, D.W.3    Brosnan, C.F.4    Berman, J.W.5
  • 23
    • 0030587864 scopus 로고    scopus 로고
    • Expression of type II nitric oxide synthase in primary human astrocytes and microglia: role of IL-1beta and IL-1 receptor antagonist
    • Liu J., Zhao M.L., Brosnan C.F., and Lee S.C. Expression of type II nitric oxide synthase in primary human astrocytes and microglia: role of IL-1beta and IL-1 receptor antagonist. J. Immunol. 157 (1996) 3569-3576
    • (1996) J. Immunol. , vol.157 , pp. 3569-3576
    • Liu, J.1    Zhao, M.L.2    Brosnan, C.F.3    Lee, S.C.4
  • 25
    • 1542327277 scopus 로고    scopus 로고
    • Inhibitors of JAKs/STATs and the kinases: a possible new cluster of drugs
    • Luo C., and Laaja P. Inhibitors of JAKs/STATs and the kinases: a possible new cluster of drugs. Drug Discov. Today 15 (2004) 268-275
    • (2004) Drug Discov. Today , vol.15 , pp. 268-275
    • Luo, C.1    Laaja, P.2
  • 26
    • 0032450274 scopus 로고    scopus 로고
    • Glial cell reactions in neurodegenerative diseases: pathophysiology and therapeutic interventions
    • McGeer P.L., and McGeer E.G. Glial cell reactions in neurodegenerative diseases: pathophysiology and therapeutic interventions. Alzheimer Dis. Assoc. Disord. 12 Suppl. 2 (1998) S1-S6
    • (1998) Alzheimer Dis. Assoc. Disord. , vol.12 , Issue.SUPPL. 2
    • McGeer, P.L.1    McGeer, E.G.2
  • 27
    • 14944352071 scopus 로고    scopus 로고
    • Inflammation and the degenerative diseases of aging
    • McGeer P.L., and McGeer E.G. Inflammation and the degenerative diseases of aging. Ann. N. Y. Acad. Sci. 1035 (2004) 104-116
    • (2004) Ann. N. Y. Acad. Sci. , vol.1035 , pp. 104-116
    • McGeer, P.L.1    McGeer, E.G.2
  • 28
    • 30444443297 scopus 로고    scopus 로고
    • Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys
    • Miklossy J., Doudet D.D., Schwab C., Yu S., McGeer E.G., and McGeer P.L. Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys. Exp. Neurol. 197 (2006) 275-283
    • (2006) Exp. Neurol. , vol.197 , pp. 275-283
    • Miklossy, J.1    Doudet, D.D.2    Schwab, C.3    Yu, S.4    McGeer, E.G.5    McGeer, P.L.6
  • 30
    • 0031441350 scopus 로고    scopus 로고
    • Interferon gamma gene expression in sensory neurons: evidence for autocrine gene regulation
    • Neumann H., Schmidt H., Wilharm E., Behrens L., and Wekerle H. Interferon gamma gene expression in sensory neurons: evidence for autocrine gene regulation. J. Exp. Med. 186 (1997) 2023-2031
    • (1997) J. Exp. Med. , vol.186 , pp. 2023-2031
    • Neumann, H.1    Schmidt, H.2    Wilharm, E.3    Behrens, L.4    Wekerle, H.5
  • 31
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes: cellular and molecular cues to biological function
    • Ridet J.L., Malhotra S.K., Privat A., and Gage F.H. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci. 20 (1997) 570-577
    • (1997) Trends Neurosci. , vol.20 , pp. 570-577
    • Ridet, J.L.1    Malhotra, S.K.2    Privat, A.3    Gage, F.H.4
  • 32
    • 0024157709 scopus 로고
    • Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease
    • Rogers J., Luber-Narod J., Styren S.D., and Civin W.H. Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease. Neurobiol. Aging 9 (1988) 339-349
    • (1988) Neurobiol. Aging , vol.9 , pp. 339-349
    • Rogers, J.1    Luber-Narod, J.2    Styren, S.D.3    Civin, W.H.4
  • 33
    • 2942611429 scopus 로고    scopus 로고
    • Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease
    • Schwab C., Hosokawa M., and McGeer P.L. Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease. Exp. Neurol. 188 (2004) 52-64
    • (2004) Exp. Neurol. , vol.188 , pp. 52-64
    • Schwab, C.1    Hosokawa, M.2    McGeer, P.L.3
  • 34
    • 0027161306 scopus 로고
    • Human astrocyte production of tumour necrosis factor-alpha, interleukin-1 beta, and interleukin-6 following exposure to lipopolysaccharide endotoxin
    • Sharif S.F., Hariri R.J., Chang V.A., Barie P.S., Wang R.S., and Ghajar J.B. Human astrocyte production of tumour necrosis factor-alpha, interleukin-1 beta, and interleukin-6 following exposure to lipopolysaccharide endotoxin. Neurol. Res. 15 (1993) 109-112
    • (1993) Neurol. Res. , vol.15 , pp. 109-112
    • Sharif, S.F.1    Hariri, R.J.2    Chang, V.A.3    Barie, P.S.4    Wang, R.S.5    Ghajar, J.B.6
  • 35
    • 0242468041 scopus 로고    scopus 로고
    • Regulation of JAK-STAT signalling in the immune system
    • Shuai K., and Liu B. Regulation of JAK-STAT signalling in the immune system. Nat. Rev. Immunol. 3 (2003) 900-911
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 900-911
    • Shuai, K.1    Liu, B.2
  • 36
    • 33645210857 scopus 로고    scopus 로고
    • Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
    • Song J.H., Bellail A., Tse M.C., Yong V.W., and Hao C. Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. J. Neurosci. 26 (2006) 3299-3308
    • (2006) J. Neurosci. , vol.26 , pp. 3299-3308
    • Song, J.H.1    Bellail, A.2    Tse, M.C.3    Yong, V.W.4    Hao, C.5
  • 37
    • 0033914409 scopus 로고    scopus 로고
    • Astrocyte-derived nitric oxide causes both reversible and irreversible damage to the neuronal mitochondrial respiratory chain
    • Stewart V.C., Sharpe M.A., Clark J.B., and Heales S.J. Astrocyte-derived nitric oxide causes both reversible and irreversible damage to the neuronal mitochondrial respiratory chain. J. Neurochem. 75 (2000) 694-700
    • (2000) J. Neurochem. , vol.75 , pp. 694-700
    • Stewart, V.C.1    Sharpe, M.A.2    Clark, J.B.3    Heales, S.J.4
  • 38
    • 33745096234 scopus 로고    scopus 로고
    • Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release
    • Thornton P., Pinteaux E., Gibson R.M., Allan S.M., and Rothwell N.J. Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release. J. Neurochem. 98 (2006) 258-266
    • (2006) J. Neurochem. , vol.98 , pp. 258-266
    • Thornton, P.1    Pinteaux, E.2    Gibson, R.M.3    Allan, S.M.4    Rothwell, N.J.5
  • 39
    • 0025806367 scopus 로고
    • Temperature-dependent modulation of lipopolysaccharide-induced interleukin-1 beta and tumor necrosis factor alpha expression in cultured human astroglial cells by dexamethasone and indomethacin
    • Velasco S., Tarlow M., Olsen K., Shay J.W., McCracken Jr. G.H., and Nisen P.D. Temperature-dependent modulation of lipopolysaccharide-induced interleukin-1 beta and tumor necrosis factor alpha expression in cultured human astroglial cells by dexamethasone and indomethacin. J. Clin. Invest. 87 (1991) 1674-1680
    • (1991) J. Clin. Invest. , vol.87 , pp. 1674-1680
    • Velasco, S.1    Tarlow, M.2    Olsen, K.3    Shay, J.W.4    McCracken Jr., G.H.5    Nisen, P.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.