Pine bark extract pycnogenol downregulates IFN-γ-induced adhesion of T cells to human keratinocytes by inhibiting inducible ICAM-1 expression

Free Radical Biology and Medicine

Volumn 28, Issue 2, 2000, Pages 219-227

  Bito, Toshinori ^a   Roy, Sashwati ^a   Sen, Chandan K ^a   Packer, Lester ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Flavonoids; Free radicals; Plant polyphenols; Procyanidins; Reactive oxygen species; Skin inflammation; Stat1

Indexed keywords

FREE RADICAL; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; PLANT EXTRACT; PYCNOGENOL; REACTIVE OXYGEN METABOLITE;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ADHESION; HUMAN; HUMAN CELL; KERATINOCYTE; LEUKEMIA CELL LINE; PINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INFLAMMATION; T LYMPHOCYTE; TRANSCRIPTION REGULATION;

ANTIOXIDANTS; CELL ADHESION; CELL LINE; FLAVONOIDS; GENE EXPRESSION REGULATION; GYMNOSPERMS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; JURKAT CELLS; KERATINOCYTES; OLIGONUCLEOTIDE PROBES; RNA, MESSENGER; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC; TREES;

PINUS PINASTER;

EID: 0033950188     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00229-4     Document Type: Article

References (39)

1. Nickoloff B.J., Griffiths C.E., Barker J.N. The role of adhesion molecules, chemotactic factors, and cytokines in inflammatory and neoplastic skin disease - 1990 update. J. Invest. Dermatol. 94:(Suppl 6):1990;151S-157S.
2. Norris D.A. Cytokine modulation of adhesion molecules in the regulation of immunologic cytotoxicity of epidermal targets. J. Invest. Dermatol. 95:(Suppl 6):1990;111S-120S.
3. Singer K.H., Tuck D.T., Sampson H.A., Hall R.P. Epidermal keratinocytes express the adhesion molecule intercellular adhesion molecule-1 in inflammatory dermatoses. J. Invest. Dermatol. 92:1989;746-750.
4. Lewis R.E., Buchsbaum M., Whitaker D., Murphy G.F. Intercellular adhesion molecule expression in the evolving human cutaneous delayed hypersensitivity reaction. J. Invest. Dermatol. 93:1989;672-677.
5. Bennion S.D., Middleton M.H., David-Bajar K.M., Brice S., Norris D.A. In three types of interface dermatitis, different patterns of expression of intercellular adhesion molecule-1 (ICAM-1) indicate different triggers of disease. J. Invest. Dermatol. 105:(Suppl 1):1995;71S-79S.
6. Siu G., Springer E.A., Hedrick S.M. The biology of the T-cell antigen receptor and its role in the skin immune system. J. Invest. Dermatol. 94:(Suppl 6):1990;91S-100S.
7. Pestka S., Langer J.A., Zoon K.C., Samuel C.E. Interferons and their actions. Annu. Rev. Biochem. 56:1987;727-777.
8. Caughman S.W., Li L.J., Degitz K. Human intercellular adhesion molecule-1 gene and its expression in the skin. J. Invest. Dermatol. 98:(Suppl 6):1992;61S-65S.
9. Stuttgen, G. The present status of anti-inflammatory agents in dermatology. Drugs 36(Suppl 5):43-48; 1988 (discussion 49-50).
10. Tharp M.D. Chronic urticaria pathophysiology and treatment approaches . J. Allergy Clin. Immunol. 98:(6 Pt 3):1996;S325-S330.
11. Barnetson R.S., White A.D. The use of corticosteroids in dermatological practice. Med. J. Aust. 156:1992;428-431.
12. Dutz J.P., Ho V.C. Immunosuppressive agents in dermatology. An update. Dermatol. Clin. 16:1998;235-251.
13. Packer L., Rimbach G., Virgili F. Antioxidant activity and biological properties of a procyanidin-rich extract from pine (Pinus maritima) bark, Pycnogenol. Free Radic. Biol. Med. 27:1999;704-724.
14. Morel I., Lescoat G., Cogrel P., Sergent O., Pasdeloup N., Brissot P., Cillard P., Cillard J. Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures. Biochem. Pharmacol. 45:1993;13-19.
15. Negre-Salvayre A., Salvayre R. Quercetin prevents the cytotoxicity of oxidized LDL on lymphoid cell lines. Free Radic. Biol. Med. 12:1992;101-106.
16. Rice-Evans, C. A.; Miller, N. J.; Paganga, G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic. Biol. Med. 20:933-956; 1996 (Published erratum appears in Free Radic. Biol. Med. 21:417; 1996).
17. Rice-Evans, C. A.; Miller, N. J.; Paganga, G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic. Biol. Med. 20:933-956; 1996 (Published erratum appears in Free Radic. Biol. Med. 21:417; 1996).
18. Salah N., Miller N.J., Paganga G., Tijburg L., Bolwell G.P., Rice-Evans C. Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants. Arch. Biochem. Biophys. 322:1995;339-346.
19. Alcaraz M.J., Villar A. Anti-inflammatory effects of natural compounds. Miguel J. CRC handbook of free radicals and antioxidants in bio medicine. Vol. 2. 1989;77-85 CRC Press, Boca Raton, FL.
20. Gerritsen M.E., Carley W.W., Ranges G.E., Shen C.P., Phan S.A., Ligon G.F., Perry C.A. Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression. (see comments) Am. J. Pathol. 147:1995;278-292.
21. Kobuchi, H.; Roy, S.; Sen, K. C.; Nguyen, G. H.; Packer, L. Quercetin inhibits inducible ICAM-1 expression in human endothelial cells through the JNK pathway. Am. J. Physiol. Cell Physiol. 277(3 Pt 1):C403-C411; 1999.
22. Roy S., Sen C.K., Packer L. Determination of cell-cell adhesion in response to oxidants and antioxidants. Meth. Enzymol. 300:1999;395-401.
23. Roy S., Sen C.K., Kobuchi H., Packer L. Antioxidant regulation of phorbol ester-induced adhesion of human Jurkat T-cells to endothelial cells. Free Radic. Biol. Med. 25:1998;229-241.
24. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
25. Dustin M.L., Singer K.H., Tuck D.T., Springer T.A. Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1). J. Exp. Med. 167:1988;1323-1340.
26. Boukamp P., Petrussevska R.T., Breitkreutz D., Hornung J., Markham A., Fusenig N.E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 106:1988;761-771.
27. Winiski A.P., Foster C.A. ICAM-1 expression in a spontaneously transformed human keratinocyte cell line characterization by a simple cell-ELISA assay . J. Invest. Dermatol. 99:1992;48-52.
28. Bevilacqua M.P. Endothelial-leukocyte adhesion molecules. Annu. Rev. Immunol. 11:1993;767-804.
29. Middleton M.H., Norris D.A. Cytokine-induced ICAM-1 expression in human keratinocytes is highly variable in keratinocyte strains from different donors. J. Invest. Dermatol. 104:1995;489-496.
30. Look D.C., Pelletier M.R., Holtzman M.J. Selective interaction of a subset of interferon-gamma response element-binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells. J. Biol. Chem. 269:1994;8952-8958.
31. Krutmann J., Czech W., Parlow F., Trefzer U., Kapp A., Schopf E., Luger T.A. Ultraviolet radiation effects on human keratinocyte ICAM-1 expression UV-induced inhibition of cytokine-induced ICAM-1 mRNA expression is transient, differentially restored for IFN gamma versus TNF alpha, and followed by ICAM-1 induction via a TNF alpha-like pathway . J. Invest. Dermatol. 98:1992;923-928.
32. Naik S.M., Shibagaki N., Li L.J., Quinlan K.L., Paxton L.L., Caughman S.W. Interferon gamma-dependent induction of human intercellular adhesion molecule-1 gene expression involves activation of a distinct STAT protein complex. J. Biol. Chem. 272:1997;1283-1290.
33. Duff J.L., Quinlan K.L., Paxton L.L., Naik S.M., Caughman S.W. Pervanadate mimics IFNgamma-mediated induction of ICAM-1 expression via activation of STAT proteins. J. Invest. Dermatol. 108:1997;295-301.
34. Yuan J., Wegenka U.M., Lutticken C., Buschmann J., Decker T., Schindler C., Heinrich P.C., Horn F. The signaling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements. Mol. Cell Biol. 14:1994;1657-1668.
35. Ohmori Y., Schreiber R.D., Hamilton T.A. Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB. J. Biol. Chem. 272:1997;14899-14907.
36. Chen C.J., Lin T.T., Shively J.E. Role of interferon regulatory factor-1 in the induction of biliary glycoprotein (cell CAM-1) by interferon-gamma. J. Biol. Chem. 271:1996;28181-28188.
37. Katiyar S.K., Agarwal R., Mukhtar H. Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber officinale rhizome. Cancer Res. 56:1996;1023-1030.
38. Katiyar S.K., Matsui M.S., Elmets C.A., Mukhtar H. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin. Photochem. Photobiol. 69:1999;148-153.
39. Dreher F., Gabard B., Schwindt D.A., Maibach H.I. Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythema a human study in vivo . Br. J. Dermatol. 139:1998;332-339.