-
1
-
-
77954901331
-
Decision checkpoints in the thymus
-
Carpenter AC, Bosselut R. Decision checkpoints in the thymus. Nat Immunol. 2010;11(8):666-73.
-
(2010)
Nat Immunol.
, vol.11
, Issue.8
, pp. 666-673
-
-
Carpenter, A.C.1
Bosselut, R.2
-
2
-
-
67651155980
-
RAG: A recombinase diversified
-
Matthews AG, Oettinger MA. RAG: a recombinase diversified. Nat Immunol. 2009;10(8):817-21.
-
(2009)
Nat Immunol.
, vol.10
, Issue.8
, pp. 817-821
-
-
Matthews, A.G.1
Oettinger, M.A.2
-
3
-
-
0033581935
-
Selecting and maintaining a diverse T-cell repertoire
-
Goldrath AW, Bevan MJ. Selecting and maintaining a diverse T-cell repertoire. Nature. 1999;402(6759):255-62. (Pubitemid 129516254)
-
(1999)
Nature
, vol.402
, Issue.6759
, pp. 255-262
-
-
Goldrath, A.W.1
Bevan, M.J.2
-
4
-
-
57249094263
-
The long road to the thymus: The generation, mobilization, and circulation of T-cell progenitors in mouse and man
-
Zlotoff DA, Schwarz BA, Bhandoola A. The long road to the thymus: the generation, mobilization, and circulation of T-cell progenitors in mouse and man. Semin Immunopathol. 2008;30(4):371-82.
-
(2008)
Semin Immunopathol.
, vol.30
, Issue.4
, pp. 371-382
-
-
Zlotoff, D.A.1
Schwarz, B.A.2
Bhandoola, A.3
-
5
-
-
0028178440
-
Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8-thymocyte differentiation
-
Godfrey DI, Kennedy J, Mombaerts P, Tonegawa S, Zlotnik A. Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. J Immunol. 1994;152(10):4783-92.
-
(1994)
J Immunol.
, vol.152
, Issue.10
, pp. 4783-4792
-
-
Godfrey, D.I.1
Kennedy, J.2
Mombaerts, P.3
Tonegawa, S.4
Zlotnik, A.5
-
6
-
-
0032514764
-
Kinetics of T cell receptor beta, gamma, and delta rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44(+)CD25(+) Pro- T thymocytes
-
Capone M, Hockett RD Jr, Zlotnik A. Kinetics of T cell receptor beta, gamma, and delta rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44(+)CD25(+) Pro- T thymocytes. Proc Natl Acad Sci USA. 1998;95(21):12522-7.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.21
, pp. 12522-12527
-
-
Capone, M.1
Hockett Jr., R.D.2
Zlotnik, A.3
-
8
-
-
33645099763
-
Thymic microenvironments for T cell differentiation and selection
-
Ladi E, Yin X, Chtanova T, Robey EA. Thymic microenvironments for T cell differentiation and selection. Nat Immunol. 2006;7(4):338-43.
-
(2006)
Nat Immunol.
, vol.7
, Issue.4
, pp. 338-343
-
-
Ladi, E.1
Yin, X.2
Chtanova, T.3
Robey, E.A.4
-
9
-
-
33645069145
-
Negative selection of the T-cell repertoire: Where and when does it occur?
-
von Boehmer H, Kisielow P. Negative selection of the T-cell repertoire: where and when does it occur? Immunol Rev. 2006;209:284-9.
-
(2006)
Immunol Rev.
, vol.209
, pp. 284-289
-
-
Von Boehmer, H.1
Kisielow, P.2
-
10
-
-
0024554495
-
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
-
DOI 10.1016/0092-8674(89)90682-X
-
Murre C, McCaw PS, Baltimore D. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell. 1989;56(5):777-83. (Pubitemid 19082513)
-
(1989)
Cell
, vol.56
, Issue.5
, pp. 777-783
-
-
Murre, C.1
Schonleber, M.C.P.2
Baltimore, D.3
-
11
-
-
33745321679
-
The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of t cell precursors
-
Wang D, Claus CL, Vaccarelli G, Braunstein M, Schmitt TM, Zuniga-Pflucker JC, et al. The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors. J Immunol. 2006;177(1):109-19. (Pubitemid 43939122)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 109-119
-
-
Wang, D.1
Claus, C.L.2
Vaccarelli, G.3
Braunstein, M.4
Schmitt, T.M.5
Zuniga-Pflucker, J.C.6
Rothenberg, E.V.7
Anderson, M.K.8
-
12
-
-
0025034673
-
Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif
-
Henthorn P, Kiledjian M, Kadesch T. Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif. Science. 1990;247(4941):467-70.
-
(1990)
Science
, vol.247
, Issue.4941
, pp. 467-470
-
-
Henthorn, P.1
Kiledjian, M.2
Kadesch, T.3
-
13
-
-
0026512017
-
HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors
-
Hu JS, Olson EN, Kingston RE. HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors. Mol Cell Biol. 1992;12(3):1031-42.
-
(1992)
Mol Cell Biol.
, vol.12
, Issue.3
, pp. 1031-1042
-
-
Hu, J.S.1
Olson, E.N.2
Kingston, R.E.3
-
14
-
-
0033980393
-
Helix-loop-helix proteins: Regulators of transcription in eucaryotic organisms
-
DOI 10.1128/MCB.20.2.429-440.2000
-
Massari ME, Murre C. Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol Cell Biol. 2000;20(2):429-40. (Pubitemid 30023084)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.2
, pp. 429-440
-
-
Massari, M.E.1
Murre, C.2
-
15
-
-
0025238437
-
The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
-
Benezra R, Davis RL, Lockshon D, Turner DL, Weintraub H. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell. 1990;61(1):49-59.
-
(1990)
Cell.
, vol.61
, Issue.1
, pp. 49-59
-
-
Benezra, R.1
Davis, R.L.2
Lockshon, D.3
Turner, D.L.4
Weintraub, H.5
-
16
-
-
27544442994
-
Helix-loop-helix proteins and lymphocyte development
-
DOI 10.1038/ni1260, PII N1260
-
Murre C. Helix-loop-helix proteins and lymphocyte development. Nat Immunol. 2005;6(11):1079-86. (Pubitemid 41541785)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1079-1086
-
-
Murre, C.1
-
17
-
-
1142285361
-
Regulation of E2A gene expression in B-lymphocyte development
-
DOI 10.1016/j.molimm.2003.11.031
-
Zhuang Y, Jackson A, Pan L, Shen K, Dai M. Regulation of E2A gene expression in B-lymphocyte development. Mol Immunol. 2004;40(16):1165-77. (Pubitemid 38210269)
-
(2004)
Molecular Immunology
, vol.40
, Issue.16
, pp. 1165-1177
-
-
Zhuang, Y.1
Jackson, A.2
Pan, L.3
Shen, K.4
Dai, M.5
-
18
-
-
0035903286
-
Early thymocyte development is regulated by modulation of E2A protein activity
-
DOI 10.1084/jem.194.6.733
-
Engel I, Johns C, Bain G, Rivera RR, Murre C. Early thymocyte development is regulated by modulation of E2A protein activity. J Exp Med. 2001;194(6):733-45. (Pubitemid 32983010)
-
(2001)
Journal of Experimental Medicine
, vol.194
, Issue.6
, pp. 733-745
-
-
Engel, I.1
Johns, C.2
Bain, G.3
Rivera, R.R.4
Murre, C.5
-
19
-
-
33645057683
-
Progression of regulatory gene expression states in fetal and adult pro-T-cell development
-
David-Fung ES, Yui MA, Morales M, Wang H, Taghon T, Diamond RA, et al. Progression of regulatory gene expression states in fetal and adult pro-T-cell development. Immunol Rev. 2006;209:212-36.
-
(2006)
Immunol Rev.
, vol.209
, pp. 212-236
-
-
David-Fung, E.S.1
Yui, M.A.2
Morales, M.3
Wang, H.4
Taghon, T.5
Diamond, R.A.6
-
21
-
-
0037090164
-
An analysis of T cell intrinsic roles of E2a by conditional gene disruption in the thymus
-
Pan L, Hanrahan J, Li J, Hale LP, Zhuang Y. An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus. J Immunol. 2002;168(8):3923-32. (Pubitemid 34298396)
-
(2002)
Journal of Immunology
, vol.168
, Issue.8
, pp. 3923-3932
-
-
Pan, L.1
Hanrahan, J.2
Li, J.3
Hale, L.P.4
Zhuang, Y.5
-
22
-
-
0035260791
-
Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade
-
DOI 10.1038/84273
-
Bain G, Cravatt CB, Loomans C, Alberola-Ila J, Hedrick SM, Murre C. Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade. Nat Immunol. 2001;2(2):165-71. (Pubitemid 33707937)
-
(2001)
Nature Immunology
, vol.2
, Issue.2
, pp. 165-171
-
-
Bain, G.1
Cravatt, C.B.2
Loomans, C.3
Alberola-Ila, J.4
Hedrick, S.M.5
Murre, C.6
-
23
-
-
59849096559
-
Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint
-
Koltsova EK, Ciofani M, Benezra R, Miyazaki T, Clipstone N, Zuniga-Pflucker JC, et al. Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint. J Immunol. 2007;179(7):4694-703.
-
(2007)
J Immunol.
, vol.179
, Issue.7
, pp. 4694-4703
-
-
Koltsova, E.K.1
Ciofani, M.2
Benezra, R.3
Miyazaki, T.4
Clipstone, N.5
Zuniga-Pflucker, J.C.6
-
24
-
-
0033984819
-
Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3
-
Rivera RR, Johns CP, Quan J, Johnson RS, Murre C. Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity. 2000;12(1):17-26.
-
(2000)
Immunity
, vol.12
, Issue.1
, pp. 17-26
-
-
Rivera, R.R.1
Johns, C.P.2
Quan, J.3
Johnson, R.S.4
Murre, C.5
-
25
-
-
0027992622
-
E2A proteins are required for proper b cell development and initiation of immunoglobulin gene rearrangements
-
DOI 10.1016/0092-8674(94)90077-9
-
Bain G, Maandag EC, Izon DJ, Amsen D, Kruisbeek AM, Weintraub BC, et al. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell. 1994;79(5):885-92. (Pubitemid 24371978)
-
(1994)
Cell
, vol.79
, Issue.5
, pp. 885-892
-
-
Bain, G.1
Maandag, E.C.R.2
Izon, D.J.3
Amsen, D.4
Kruisbeek, A.M.5
Weintraub, B.C.6
Krop, I.7
Schlissel, M.S.8
Feeney, A.J.9
Van Roon, M.10
Van Der, V.M.11
Te, R.H.P.J.12
Berns, A.13
Murre, C.14
-
26
-
-
0028148938
-
The helix-loop-helix gene E2A is required for B cell formation
-
DOI 10.1016/0092-8674(94)90076-0
-
Zhuang Y, Soriano P, Weintraub H. The helix-loop-helix gene E2A is required for B cell formation. Cell. 1994;79(5):875-84. (Pubitemid 24371977)
-
(1994)
Cell
, vol.79
, Issue.5
, pp. 875-884
-
-
Zhuang, Y.1
Soriano, P.2
Weintraub, H.3
-
27
-
-
0030752361
-
E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas
-
Bain G, Engel I, Robanus Maandag EC, te Riele HP, Voland JR, Sharp LL, et al. E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol Cell Biol. 1997;17(8):4782-91.
-
(1997)
Mol Cell Biol.
, vol.17
, Issue.8
, pp. 4782-4791
-
-
Bain, G.1
Engel, I.2
Robanus Maandag, E.C.3
Te Riele, H.P.4
Voland, J.R.5
Sharp, L.L.6
-
28
-
-
0033568023
-
A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alphabeta thymopoiesis
-
Barndt R, Dai MF, Zhuang Y. A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis. J Immunol. 1999;163(6):3331-43. (Pubitemid 29431835)
-
(1999)
Journal of Immunology
, vol.163
, Issue.6
, pp. 3331-3343
-
-
Barndt, R.1
Dai, M.-F.2
Zhuang, Y.3
-
29
-
-
0029896451
-
B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB
-
Zhuang Y, Cheng P, Weintraub H. B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. Mol Cell Biol. 1996;16(6):2898-905. (Pubitemid 26161295)
-
(1996)
Molecular and Cellular Biology
, vol.16
, Issue.6
, pp. 2898-2905
-
-
Zhuang, Y.1
Cheng, P.2
Weintraub, H.3
-
30
-
-
30444454357
-
Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus
-
DOI 10.1016/j.immuni.2005.11.012, PII S1074761305004073
-
Taghon T, Yui MA, Pant R, Diamond RA, Rothenberg EV. Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus. Immunity. 2006;24(1):53-64. (Pubitemid 43077200)
-
(2006)
Immunity
, vol.24
, Issue.1
, pp. 53-64
-
-
Taghon, T.1
Yui, M.A.2
Pant, R.3
Diamond, R.A.4
Rothenberg, E.V.5
-
31
-
-
0033811622
-
Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB
-
Barndt RJ, Dai M, Zhuang Y. Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB. Mol Cell Biol. 2000;20(18):6677-85.
-
(2000)
Mol Cell Biol.
, vol.20
, Issue.18
, pp. 6677-6685
-
-
Barndt, R.J.1
Dai, M.2
Zhuang, Y.3
-
32
-
-
0027237711
-
A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines
-
Sawada S, Littman DR. A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines. Mol Cell Biol. 1993;13(9):5620-8. (Pubitemid 23260664)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.9
, pp. 5620-5628
-
-
Sawada, S.1
Littman, D.R.2
-
33
-
-
0031867289
-
Functional replacement of the mouse E2A gene with a human HEB cDNA
-
Zhuang Y, Barndt RJ, Pan L, Kelley R, Dai M. Functional replacement of the mouse E2A gene with a human HEB cDNA. Mol Cell Biol. 1998;18(6):3340-9. (Pubitemid 28240506)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.6
, pp. 3340-3349
-
-
Zhuang, Y.1
Barndt, R.J.2
Pan, L.3
Kelley, R.4
Dai, M.5
-
34
-
-
34247627897
-
E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression
-
Wojciechowski J, Lai A, Kondo M, Zhuang Y. E2A and HEB Are Required to Block Thymocyte Proliferation Prior to Pre-TCR Expression. J Immunol. 2007;178(9):5717-26. (Pubitemid 46674368)
-
(2007)
Journal of Immunology
, vol.178
, Issue.9
, pp. 5717-5726
-
-
Wojciechowski, J.1
Lai, A.2
Kondo, M.3
Zhuang, Y.4
-
35
-
-
34247630198
-
Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion
-
DOI 10.1038/sj.emboj.7601671, PII 7601671
-
Jia J, Kondo M, Zhuang Y. Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion. EMBO J. 2007;26(9):2387-99. (Pubitemid 46685854)
-
(2007)
EMBO Journal
, vol.26
, Issue.9
, pp. 2387-2399
-
-
Jia, J.1
Kondo, M.2
Zhuang, Y.3
-
36
-
-
70449113023
-
A tamoxifen inducible knock-in allele for investigation of E2A function
-
Jones ME, Kondo M, Zhuang Y. A tamoxifen inducible knock-in allele for investigation of E2A function. BMC Dev Biol. 2009;9:51.
-
(2009)
BMC Dev Biol.
, vol.9
, pp. 51
-
-
Jones, M.E.1
Kondo, M.2
Zhuang, Y.3
-
37
-
-
33746900091
-
E2A promotes the survival of precursor and mature B lymphocytes
-
Lazorchak AS, Wojciechowski J, Dai M, Zhuang Y. E2A promotes the survival of precursor and mature B lymphocytes. J Immunol. 2006;177(4):2495-504. (Pubitemid 44201009)
-
(2006)
Journal of Immunology
, vol.177
, Issue.4
, pp. 2495-2504
-
-
Lazorchak, A.S.1
Wojciechowski, J.2
Dai, M.3
Zhuang, Y.4
-
38
-
-
21844440323
-
Unique features of the pre-T-cell receptor alpha-chain: Not just a surrogate
-
von Boehmer H. Unique features of the pre-T-cell receptor alpha-chain: not just a surrogate. Nat Rev Immunol. 2005;5(7):571-7.
-
(2005)
Nat Rev Immunol.
, vol.5
, Issue.7
, pp. 571-577
-
-
Von Boehmer, H.1
-
39
-
-
58149250582
-
E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene
-
Jia J, Dai M, Zhuang Y. E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene. Eur J Immunol. 2008;38(10):2806-20.
-
(2008)
Eur J Immunol.
, vol.38
, Issue.10
, pp. 2806-2820
-
-
Jia, J.1
Dai, M.2
Zhuang, Y.3
-
40
-
-
3543011330
-
The T-cell receptor beta variable gene promoter is required for efficient Vbeta rearrangement but not allelic exclusion
-
DOI 10.1128/MCB.24.16.7015-7023.2004
-
Ryu CJ, Haines BB, Lee HR, Kang YH, Draganov DD, Lee M, et al. The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion. Mol Cell Biol. 2004;24(16):7015-23. (Pubitemid 39014429)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.16
, pp. 7015-7023
-
-
Ryu, C.J.1
Haines, B.B.2
Lee, H.R.3
Kang, Y.H.4
Draganov, D.D.5
Lee, M.6
Whitehurst, C.E.7
Hong, H.J.8
Chen, J.9
-
41
-
-
0029983727
-
Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements
-
DOI 10.1146/annurev.immunol.14.1.459
-
Sleckman BP, Gorman JR, Alt FW. Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements. Annu Rev Immunol. 1996;14:459-81. (Pubitemid 26130191)
-
(1996)
Annual Review of Immunology
, vol.14
, pp. 459-481
-
-
Sleckman, B.P.1
Gorman, J.R.2
Alt, F.W.3
-
42
-
-
33748850103
-
Regulation of T cell receptor-alpha gene recombination by transcription
-
Abarrategui I, Krangel MS. Regulation of T cell receptor-alpha gene recombination by transcription. Nat Immunol. 2006;7(10):1109-15.
-
(2006)
Nat Immunol.
, vol.7
, Issue.10
, pp. 1109-1115
-
-
Abarrategui, I.1
Krangel, M.S.2
-
43
-
-
0035253709
-
Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement
-
Chen F, Rowen L, Hood L, Rothenberg EV. Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement. J Immunol. 2001;166(3):1771-80. (Pubitemid 32114662)
-
(2001)
Journal of Immunology
, vol.166
, Issue.3
, pp. 1771-1780
-
-
Chen, F.1
Rowen, L.2
Hood, L.3
Rothenberg, E.V.4
-
44
-
-
0035911252
-
Induction of a diverse T cell receptor gamma/delta repertoire by the helix-loop-helix proteins E2A and HEB in nonlymphoid cells
-
Ghosh JK, Romanow WJ, Murre C. Induction of a diverse T cell receptor gamma/delta repertoire by the helix-loop-helix proteins E2A and HEB in nonlymphoid cells. J Exp Med. 2001;193(6):769-76.
-
(2001)
J Exp Med.
, vol.193
, Issue.6
, pp. 769-776
-
-
Ghosh, J.K.1
Romanow, W.J.2
Murre, C.3
-
45
-
-
0025036184
-
Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: Common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes
-
Gottschalk LR, Leiden JM. Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes. Mol Cell Biol. 1990;10(10):5486-95.
-
(1990)
Mol Cell Biol.
, vol.10
, Issue.10
, pp. 5486-5495
-
-
Gottschalk, L.R.1
Leiden, J.M.2
-
46
-
-
0024342647
-
A T-cell-specific transcriptional enhancer element 3' of C(alpha) in the human T-cell receptor alpha locus
-
Ho IC, Yang LH, Morle G, Leiden JM. A T-cell-specific transcriptional enhancer element 3′ of C alpha in the human T-cell receptor alpha locus. Proc Natl Acad Sci USA. 1989;86(17):6714-8. (Pubitemid 19236334)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.17
, pp. 6714-6718
-
-
Ho, I.-C.1
Yang, L.-H.2
Morle, G.3
Leiden, J.M.4
-
47
-
-
0024997739
-
Functional analysis of the murine T-cell receptor beta enhancer and characteristics of its DNA-binding proteins
-
Takeda J, Cheng A, Mauxion F, Nelson CA, Newberry RD, Sha WC, et al. Functional analysis of the murine T-cell receptor beta enhancer and characteristics of its DNA-binding proteins. Mol Cell Biol. 1990;10(10):5027-35.
-
(1990)
Mol Cell Biol.
, vol.10
, Issue.10
, pp. 5027-5035
-
-
Takeda, J.1
Cheng, A.2
Mauxion, F.3
Nelson, C.A.4
Newberry, R.D.5
Sha, W.C.6
-
48
-
-
0031040278
-
Specific transcription of the unrearranged TCR Vbeta8.2 gene in lymphoid tissues occurs independently of V(D)J rearrangement
-
Jolly CJ, O'Neill HC. Specific transcription of the unrearranged TCR V beta 8.2 gene in lymphoid tissues occurs independently of V(D)J rearrangement. Immunol Cell Biol. 1997;75(1):13-20. (Pubitemid 27101402)
-
(1997)
Immunology and Cell Biology
, vol.75
, Issue.1
, pp. 13-20
-
-
Jolly, C.J.1
O'Neill, H.C.2
-
49
-
-
37049009268
-
Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47
-
Agata Y, Tamaki N, Sakamoto S, Ikawa T, Masuda K, Kawamoto H, et al. Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47. Immunity. 2007;27(6):871-84.
-
(2007)
Immunity
, vol.27
, Issue.6
, pp. 871-884
-
-
Agata, Y.1
Tamaki, N.2
Sakamoto, S.3
Ikawa, T.4
Masuda, K.5
Kawamoto, H.6
-
50
-
-
70349569246
-
Regulation of V(D)J recombination by E-protein transcription factors
-
Jones ME, Zhuang Y. Regulation of V(D)J recombination by E-protein transcription factors. Adv Exp Med Biol. 2009;650:148-56.
-
(2009)
Adv Exp Med Biol.
, vol.650
, pp. 148-156
-
-
Jones, M.E.1
Zhuang, Y.2
-
51
-
-
0034252945
-
SCL and LMO1 alter thymocyte differentiation: Inhibition of E2A-HEB function and pre-T alpha chain expression
-
Herblot S, Steff AM, Hugo P, Aplan PD, Hoang T. SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression. Nat Immunol. 2000;1(2):138-44.
-
(2000)
Nat Immunol.
, vol.1
, Issue.2
, pp. 138-144
-
-
Herblot, S.1
Steff, A.M.2
Hugo, P.3
Aplan, P.D.4
Hoang, T.5
-
52
-
-
0035881544
-
E2A and HEB activate the pre-TCRalpha promoter during immature T cell development
-
Takeuchi A, Yamasaki S, Takase K, Nakatsu F, Arase H, Onodera M, et al. E2A and HEB activate the pre-TCR alpha promoter during immature T cell development. J Immunol. 2001;167(4):2157-63. (Pubitemid 32747525)
-
(2001)
Journal of Immunology
, vol.167
, Issue.4
, pp. 2157-2163
-
-
Takeuchi, A.1
Yamasaki, S.2
Takase, K.3
Nakatsu, F.4
Arase, H.5
Onodera, M.6
Saito, T.7
-
53
-
-
0036201826
-
The pTalpha promoter and enhancer are direct targets for transactivation by e box-binding proteins
-
DOI 10.1002/1521-4141(200203)32:3<911::AID-IMMU911>3.0.CO;2-H
-
Petersson K, Ivars F, Sigvardsson M. The pT alpha promoter and enhancer are direct targets for transactivation by E box-binding proteins. Eur J Immunol. 2002;32(3):911-20. (Pubitemid 34257569)
-
(2002)
European Journal of Immunology
, vol.32
, Issue.3
, pp. 911-920
-
-
Petersson, K.1
Ivars, F.2
Sigvardsson, M.3
-
54
-
-
0038805207
-
Regulation of pTalpha gene expression by a dosage of E2A, HEB, and SCL
-
DOI 10.1074/jbc.M209870200
-
Tremblay M, Herblot S, Lecuyer E, Hoang T. Regulation of pT alpha gene expression by a dosage of E2A, HEB, and SCL. J Biol Chem. 2003;278(15):12680-7. (Pubitemid 36800028)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.15
, pp. 12680-12687
-
-
Tremblay, M.1
Herblot, S.2
Lecuyer, E.3
Hoang, T.4
-
55
-
-
0033103833
-
Essential role of LAT in T cell development
-
Zhang W, Sommers CL, Burshtyn DN, Stebbins CC, DeJarnette JB, Trible RP, et al. Essential role of LAT in T cell development. Immunity. 1999;10(3):323-32. (Pubitemid 29165287)
-
(1999)
Immunity
, vol.10
, Issue.3
, pp. 323-332
-
-
Zhang, W.1
Sommers, C.L.2
Burshtyn, D.N.3
Stebbins, C.C.4
DeJarnette, J.B.5
Trible, R.P.6
Grinberg, A.7
Tsay, H.C.8
Jacobs, H.M.9
Kessler, C.M.10
Long, E.O.11
Love, P.E.12
Samelson, L.E.13
-
56
-
-
0029065488
-
Crucial role of the pre-T-cell receptor alpha gene in development of alpha beta but not gamma delta T cells
-
Fehling HJ, Krotkova A, Saint-Ruf C, von Boehmer H. Crucial role of the pre-T-cell receptor alpha gene in development of alpha beta but not gamma delta T cells. Nature. 1995;375(6534):795-8.
-
(1995)
Nature
, vol.375
, Issue.6534
, pp. 795-798
-
-
Fehling, H.J.1
Krotkova, A.2
Saint-Ruf, C.3
Von Boehmer, H.4
-
57
-
-
0842285394
-
E2A proteins enforce a proliferation checkpoint in developing thymocytes
-
DOI 10.1038/sj.emboj.7600017
-
Engel I, Murre C. E2A proteins enforce a proliferation checkpoint in developing thymocytes. EMBO J. 2004;23(1):202-11. (Pubitemid 38165760)
-
(2004)
EMBO Journal
, vol.23
, Issue.1
, pp. 202-211
-
-
Engel, I.1
Murre, C.2
-
58
-
-
0029924217
-
Productive T-cell receptor beta-chain gene rearrangement: Coincident regulation of cell cycle and clonality during development in vivo
-
Hoffman ES, Passoni L, Crompton T, Leu TM, Schatz DG, Koff A, et al. Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo. Genes Dev. 1996;10(8):948-62. (Pubitemid 26138706)
-
(1996)
Genes and Development
, vol.10
, Issue.8
, pp. 948-962
-
-
Hoffman, E.S.1
Passoni, L.2
Crompton, T.3
Leu, T.M.J.4
Schatz, D.G.5
Koff, A.6
Owen, M.J.7
Hayday, A.C.8
-
59
-
-
0030911340
-
T cell receptor (TCR)-beta gene recombination: Dissociation from cell cycle regulation and developmental progression during T cell ontogeny
-
DOI 10.1084/jem.185.9.1549
-
Tourigny MR, Mazel S, Burtrum DB, Petrie HT. T cell receptor (TCR)-beta gene recombination: dissociation from cell cycle regulation and developmental progression during T cell ontogeny. J Exp Med. 1997;185(9):1549-56. (Pubitemid 27203251)
-
(1997)
Journal of Experimental Medicine
, vol.185
, Issue.9
, pp. 1549-1556
-
-
Tourigny, M.R.1
Mazel, S.2
Burtrum, D.B.3
Petrie, H.T.4
-
60
-
-
22544452762
-
Cell biology of IL-7, a key lymphotrophin
-
DOI 10.1016/j.cytogfr.2005.05.004, PII S1359610105000626
-
Jiang Q, Li WQ, Aiello FB, Mazzucchelli R, Asefa B, Khaled AR, et al. Cell biology of IL-7, a key lymphotrophin. Cytokine Growth Factor Rev. 2005;16(4-5):513-33. (Pubitemid 41022015)
-
(2005)
Cytokine and Growth Factor Reviews
, vol.16
, Issue.4-5
, pp. 513-533
-
-
Jiang, Q.1
Wen, Q.L.2
Aiello, F.B.3
Mazzucchelli, R.4
Asefa, B.5
Khaled, A.R.6
Durum, S.K.7
-
61
-
-
52949145604
-
Lineage fate and intense debate: Myths, models and mechanisms of CD4- Versus CD8-lineage choice
-
Singer A, Adoro S, Park JH. Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice. Nat Rev Immunol. 2008;8(10):788-801.
-
(2008)
Nat Rev Immunol.
, vol.8
, Issue.10
, pp. 788-801
-
-
Singer, A.1
Adoro, S.2
Park, J.H.3
-
62
-
-
0033405692
-
Thymocyte maturation is regulated by the activity of the helix-loop- Helix protein, E47
-
DOI 10.1084/jem.190.11.1605
-
Bain G, Quong MW, Soloff RS, Hedrick SM, Murre C. Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47. J Exp Med. 1999;190(11):1605-16. (Pubitemid 30002342)
-
(1999)
Journal of Experimental Medicine
, vol.190
, Issue.11
, pp. 1605-1616
-
-
Bain, G.1
Quong, M.W.2
Soloff, R.S.3
Hedrick, S.M.4
Murre, C.5
-
63
-
-
37049034259
-
Acquisition of a Functional T Cell Receptor during T Lymphocyte Development Is Enforced by HEB and E2A Transcription Factors
-
DOI 10.1016/j.immuni.2007.10.014, PII S1074761307005511
-
Jones ME, Zhuang Y. Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors. Immunity. 2007;27(6):860-70. (Pubitemid 350251224)
-
(2007)
Immunity
, vol.27
, Issue.6
, pp. 860-870
-
-
Jones, M.E.1
Zhuang, Y.2
-
64
-
-
0030663194
-
Function of the TCRalpha enhancer in alphabeta and gammadelta T cells
-
Sleckman BP, Bardon CG, Ferrini R, Davidson L, Alt FW. Function of the TCR alpha enhancer in alphabeta and gammadelta T cells. Immunity. 1997;7(4):505-15. (Pubitemid 27508702)
-
(1997)
Immunity
, vol.7
, Issue.4
, pp. 505-515
-
-
Sleckman, B.P.1
Bardon, C.G.2
Ferrini, R.3
Davidson, L.4
Alt, F.W.5
-
65
-
-
0029024913
-
T cell receptor gene recombination patterns and mechanisms: Cell death, rescue, and T cell production
-
Petrie HT, Livak F, Burtrum D, Mazel S. T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production. J Exp Med. 1995;182(1):121-7.
-
(1995)
J Exp Med.
, vol.182
, Issue.1
, pp. 121-127
-
-
Petrie, H.T.1
Livak, F.2
Burtrum, D.3
Mazel, S.4
-
66
-
-
0025054662
-
First T cell receptor alpha gene rearrangements during T cell ontogeny skew to the 5' region of the Jalpha locus
-
Thompson SD, Pelkonen J, Hurwitz JL. First T cell receptor alpha gene rearrangements during T cell ontogeny skew to the 5′ region of the J alpha locus. J Immunol. 1990;145(7):2347-52. (Pubitemid 20343405)
-
(1990)
Journal of Immunology
, vol.145
, Issue.7
, pp. 2347-2352
-
-
Thompson, S.D.1
Pelkonen, J.2
Hurwitz, J.L.3
-
67
-
-
0032578459
-
Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: Role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation
-
Wang F, Huang CY, Kanagawa O. Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation. Proc Natl Acad Sci USA. 1998;95(20):11834-9.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.20
, pp. 11834-11839
-
-
Wang, F.1
Huang, C.Y.2
Kanagawa, O.3
-
68
-
-
0035999828
-
+ thymocytes
-
DOI 10.1038/ni791
-
Guo J, Hawwari A, Li H, Sun Z, Mahanta SK, Littman DR, et al. Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. Nat Immunol. 2002;3(5):469-76. (Pubitemid 34520797)
-
(2002)
Nature Immunology
, vol.3
, Issue.5
, pp. 469-476
-
-
Guo, J.1
Hawwari, A.2
Li, H.3
Sun, Z.4
Mahanta, S.K.5
Littman, D.R.6
Krangel, M.S.7
He, Y.-W.8
-
69
-
-
0034730131
-
Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis
-
Kurebayashi S, Ueda E, Sakaue M, Patel DD, Medvedev A, Zhang F, et al. Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis. Proc Natl Acad Sci USA. 2000;97(18):10132-7.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.18
, pp. 10132-10137
-
-
Kurebayashi, S.1
Ueda, E.2
Sakaue, M.3
Patel, D.D.4
Medvedev, A.5
Zhang, F.6
-
70
-
-
0034733039
-
Requirement for RORgamma in thymocyte survival and lymphoid organ development
-
DOI 10.1126/science.288.5475.2369
-
Sun Z, Unutmaz D, Zou YR, Sunshine MJ, Pierani A, Brenner-Morton S, et al. Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science. 2000;288(5475):2369-73. (Pubitemid 30448162)
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2369-2373
-
-
Sun, Z.1
Unutmaz, D.2
Zou, Y.-R.3
Sunshine, M.J.4
Pierani, A.5
Brenner-Morton, S.6
Mebius, R.E.7
Littman, D.R.8
-
71
-
-
76949089741
-
An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells
-
D'Cruz LM, Knell J, Fujimoto JK, Goldrath AW. An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells. Nature Immunol. 2010;11(3):240-9.
-
(2010)
Nature Immunol.
, vol.11
, Issue.3
, pp. 240-249
-
-
D'Cruz, L.M.1
Knell, J.2
Fujimoto, J.K.3
Goldrath, A.W.4
-
72
-
-
33744977004
-
Interplay between RORgammat, Egr3, and e proteins controls proliferation in response to pre-TCR signals
-
Xi H, Schwartz R, Engel I, Murre C, Kersh GJ. Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals. Immunity. 2006;24(6):813-26.
-
(2006)
Immunity
, vol.24
, Issue.6
, pp. 813-826
-
-
Xi, H.1
Schwartz, R.2
Engel, I.3
Murre, C.4
Kersh, G.J.5
-
73
-
-
17644443312
-
+ T cell progenitors and CD4/CD8 lineage decision in the thymus
-
DOI 10.1084/jem.20021417
-
Yucel R, Karsunky H, Klein-Hitpass L, Moroy T. The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymus. J Exp Med. 2003;197(7):831-44. (Pubitemid 36437861)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.7
, pp. 831-844
-
-
Yucel, R.1
Karsunky, H.2
Klein-Hitpass, L.3
Moroy, T.4
-
74
-
-
0033785487
-
Role of the forkhead transcription family member, FKHR, in thymocyte differentiation
-
Leenders H, Whiffield S, Benoist C, Mathis D. Role of the forkhead transcription family member, FKHR, in thymocyte differentiation. Eur J Immunol. 2000;30(10):2980-90.
-
(2000)
Eur J Immunol.
, vol.30
, Issue.10
, pp. 2980-2990
-
-
Leenders, H.1
Whiffield, S.2
Benoist, C.3
Mathis, D.4
-
75
-
-
33746334804
-
Kruppel-like factor 2 regulates thymocyte and T-cell migration
-
DOI 10.1038/nature04882, PII NATURE04882
-
Carlson CM, Endrizzi BT, Wu J, Ding X, Weinreich MA, Walsh ER, et al. Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature. 2006;442(7100):299-302. (Pubitemid 44114904)
-
(2006)
Nature
, vol.442
, Issue.7100
, pp. 299-302
-
-
Carlson, C.M.1
Endrizzi, B.T.2
Wu, J.3
Ding, X.4
Weinreich, M.A.5
Walsh, E.R.6
Wani, M.A.7
Lingrel, J.B.8
Hogquist, K.A.9
Jameson, S.C.10
-
76
-
-
32244432265
-
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance
-
DOI 10.1016/j.immuni.2005.12.011, PII S1074761306000021
-
Kurobe H, Liu C, Ueno T, Saito F, Ohigashi I, Seach N, et al. CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. Immunity. 2006;24(2):165-77. (Pubitemid 43214586)
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 165-177
-
-
Kurobe, H.1
Liu, C.2
Ueno, T.3
Saito, F.4
Ohigashi, I.5
Seach, N.6
Arakaki, R.7
Hayashi, Y.8
Kitagawa, T.9
Lipp, M.10
Boyd, R.L.11
Takahama, Y.12
-
77
-
-
0036624721
-
Interleukin-7: From bench to clinic
-
DOI 10.1182/blood.V99.11.3892
-
Fry TJ, Mackall CL. Interleukin-7: from bench to clinic. Blood. 2002;99(11):3892-904. (Pubitemid 35332024)
-
(2002)
Blood
, vol.99
, Issue.11
, pp. 3892-3904
-
-
Fry, T.J.1
Mackall, C.L.2
-
78
-
-
0142149043
-
Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus
-
Plotkin J, Prockop SE, Lepique A, Petrie HT. Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus. J Immunol. 2003;171(9):4521-7. (Pubitemid 37310567)
-
(2003)
Journal of Immunology
, vol.171
, Issue.9
, pp. 4521-4527
-
-
Plotkin, J.1
Prockop, S.E.2
Lepique, A.3
Petrie, H.T.4
-
79
-
-
61349152914
-
E and ID proteins branch out
-
Kee BL. E and ID proteins branch out. Nat Rev Immunol. 2009;9(3):175-84.
-
(2009)
Nat Rev Immunol.
, vol.9
, Issue.3
, pp. 175-184
-
-
Kee, B.L.1
-
80
-
-
43449111178
-
A role for E2-2 at the DN3 stage of early thymopoiesis
-
Wikstrom I, Forssell J, Penha-Goncalves MN, Bergqvist I, Holmberg D. A role for E2-2 at the DN3 stage of early thymopoiesis. Mol Immunol. 2008;45(11):3302-11.
-
(2008)
Mol Immunol.
, vol.45
, Issue.11
, pp. 3302-3311
-
-
Wikstrom, I.1
Forssell, J.2
Penha-Goncalves, M.N.3
Bergqvist, I.4
Holmberg, D.5
-
81
-
-
0035924703
-
The regulation and function of the Id proteins in lymphocyte development
-
DOI 10.1038/sj/onc/1205091
-
Rivera R, Murre C. The regulation and function of the Id proteins in lymphocyte development. Oncogene. 2001;20(58):8308-16. (Pubitemid 34121901)
-
(2001)
Oncogene
, vol.20
, Issue.58 REV. ISS. 8
, pp. 8308-8316
-
-
Rivera, R.1
Murre, C.2
|