-
1
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000;100:655-669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
3
-
-
0345358584
-
The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses
-
Trinchieri G, Pflanz S, Kastelein RA. The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity. 2003;19:641-644.
-
(2003)
Immunity
, vol.19
, pp. 641-644
-
-
Trinchieri, G.1
Pflanz, S.2
Kastelein, R.A.3
-
4
-
-
0034661356
-
Lineage commitment in the immune system: The T helper lymphocyte grows up
-
Glimcher LH, Murphy KM. Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes Dev. 2000;14:1693-1711.
-
(2000)
Genes Dev
, vol.14
, pp. 1693-1711
-
-
Glimcher, L.H.1
Murphy, K.M.2
-
5
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell. 1997;89:587-596.
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
6
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol. 2005;6:1219-1227.
-
(2005)
Nat Immunol
, vol.6
, pp. 1219-1227
-
-
Kretschmer, K.1
Apostolou, I.2
Hawiger, D.3
Khazaie, K.4
Nussenzweig, M.C.5
von Boehmer, H.6
-
7
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T- helper cells
-
Ivanov II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T- helper cells. Cell. 2006;126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
-
8
-
-
0029847368
-
Functional diver- sity of helper T lymphocytes
-
Abbas AK, Murphy KM, Sher A. Functional diver- sity of helper T lymphocytes. Nature. 1996;383:787-793.
-
(1996)
Nature
, vol.383
, pp. 787-793
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
9
-
-
0032033419
-
Cytokines induce the development of functionally heterogeneous T-helper cell subsets
-
O'Garra A. Cytokines induce the development of functionally heterogeneous T-helper cell subsets. Immunity. 1998;8:275-283.
-
(1998)
Immunity
, vol.8
, pp. 275-283
-
-
O'Garra, A.1
-
10
-
-
3242792378
-
In vivo generated Th1 cells can migrate to B cell follicles to support B cell responses
-
Smith KM, Brewer JM, Rush CM, Riley J, Garside P. In vivo generated Th1 cells can migrate to B cell follicles to support B cell responses. J Immunol. 2004;173:1640-1646.
-
(2004)
J Immunol
, vol.173
, pp. 1640-1646
-
-
Smith, K.M.1
Brewer, J.M.2
Rush, C.M.3
Riley, J.4
Garside, P.5
-
11
-
-
0023733838
-
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells
-
Stevens TL, Bossie A, Sanders VM, et al. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature. 1988;334:255-258.
-
(1988)
Nature
, vol.334
, pp. 255-258
-
-
Stevens, T.L.1
Bossie, A.2
Sanders, V.M.3
-
12
-
-
0032550353
-
T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching
-
Toellner KM, Luther SA, Sze DM, et al. T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching. J Exp Med. 1998;187:1193-1204.
-
(1998)
J Exp Med
, vol.187
, pp. 1193-1204
-
-
Toellner, K.M.1
Luther, S.A.2
Sze, D.M.3
-
13
-
-
0033152267
-
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines
-
Kim JI, Ho IC, Grusby MJ, Glimcher LH. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity. 1999;10:745-751.
-
(1999)
Immunity
, vol.10
, pp. 745-751
-
-
Kim, J.I.1
Ho, I.C.2
Grusby, M.J.3
Glimcher, L.H.4
-
14
-
-
0029414786
-
Immune responses of IL-4, IL-5, IL-6 deficient mice
-
Kopf M, Le Gros G, Coyle AJ, Kosco-Vilbois M, Brombacher F. Immune responses of IL-4, IL-5, IL-6 deficient mice. Immunol Rev. 1995;148:45-69.
-
(1995)
Immunol Rev
, vol.148
, pp. 45-69
-
-
Kopf, M.1
Le Gros, G.2
Coyle, A.J.3
Kosco-Vilbois, M.4
Brombacher, F.5
-
15
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda K, van Deursen J, Sangster MY, et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature. 1996;380:630-633.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
van Deursen, J.2
Sangster, M.Y.3
-
16
-
-
0034606359
-
Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
-
Breitfeld D, Ohl L, Kremmer E, et al. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J Exp Med. 2000;192:1545-1552.
-
(2000)
J Exp Med
, vol.192
, pp. 1545-1552
-
-
Breitfeld, D.1
Ohl, L.2
Kremmer, E.3
-
17
-
-
0035908122
-
Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells
-
Kim CH, Rott LS, Clark-Lewis I, Campbell DJ, Wu L, Butcher EC. Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells. J Exp Med. 2001;193:1373-1381.
-
(2001)
J Exp Med
, vol.193
, pp. 1373-1381
-
-
Kim, C.H.1
Rott, L.S.2
Clark-Lewis, I.3
Campbell, D.J.4
Wu, L.5
Butcher, E.C.6
-
18
-
-
0034606348
-
CXC chemokine receptor 5 expression defines follicular homing T cells with B-cell helper function
-
Schaerli P, Willimann K, Lang AB, Lipp M, Loetscher P, Moser B. CXC chemokine receptor 5 expression defines follicular homing T cells with B-cell helper function. J Exp Med. 2000;192:1553-1562.
-
(2000)
J Exp Med
, vol.192
, pp. 1553-1562
-
-
Schaerli, P.1
Willimann, K.2
Lang, A.B.3
Lipp, M.4
Loetscher, P.5
Moser, B.6
-
19
-
-
2942755979
-
T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
-
Chtanova T, Tangye SG, Newton R, et al. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J Immunol. 2004;173:68-78.
-
(2004)
J Immunol
, vol.173
, pp. 68-78
-
-
Chtanova, T.1
Tangye, S.G.2
Newton, R.3
-
20
-
-
0032701695
-
In vivo-acti-vated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines
-
Ansel KM, McHeyzer-Williams LJ, Ngo VN, McHeyzer-Williams MG, Cyster JG. In vivo-acti-vated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines. J Exp Med. 1999;190:1123-1134.
-
(1999)
J Exp Med
, vol.190
, pp. 1123-1134
-
-
Ansel, K.M.1
McHeyzer-Williams, L.J.2
Ngo, V.N.3
McHeyzer-Williams, M.G.4
Cyster, J.G.5
-
21
-
-
25444434157
-
Interleukin-21: A modulator of lymphoid proliferation, apoptosis and differentiation
-
Leonard WJ, Spolski R. Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation. Nat Rev Immunol. 2005;5:688-698.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 688-698
-
-
Leonard, W.J.1
Spolski, R.2
-
22
-
-
0034040751
-
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
-
Follenzi A, Ailles LE, Bakovic S, Geuna M, Naldini L. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat Genet. 2000;25:217-222.
-
(2000)
Nat Genet
, vol.25
, pp. 217-222
-
-
Follenzi, A.1
Ailles, L.E.2
Bakovic, S.3
Geuna, M.4
Naldini, L.5
-
23
-
-
0842312143
-
Lentivirally transduced dendritic cells as a tool for cancer immunotherapy
-
Breckpot K, Dullaers M, Bonehill A, et al. Lentivirally transduced dendritic cells as a tool for cancer immunotherapy. J Gene Med. 2003;5:654-667.
-
(2003)
J Gene Med
, vol.5
, pp. 654-667
-
-
Breckpot, K.1
Dullaers, M.2
Bonehill, A.3
-
24
-
-
0023840199
-
cDNA cloning of murine interleukin-HP1: Homology with human interleukin 6
-
Van Snick J, Cayphas S, Szikora JP, et al. cDNA cloning of murine interleukin-HP1: homology with human interleukin 6. Eur J Immunol. 1988;18:193-197.
-
(1988)
Eur J Immunol
, vol.18
, pp. 193-197
-
-
Van Snick, J.1
Cayphas, S.2
Szikora, J.P.3
-
25
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
Liu F, Song Y, Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther. 1999;6:1258-1266.
-
(1999)
Gene Ther
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
26
-
-
33645928754
-
CD4+ CD25+ regulatory T cells control the magnitude of T-dependent humoral immune responses to exogenous antigens
-
Eddahri F, Oldenhove G, Denanglaire S, Urbain J, Leo O, ndris F. CD4+ CD25+ regulatory T cells control the magnitude of T-dependent humoral immune responses to exogenous antigens. Eur J Immunol. 2006;36:855-863.
-
(2006)
Eur J Immunol
, vol.36
, pp. 855-863
-
-
Eddahri, F.1
Oldenhove, G.2
Denanglaire, S.3
Urbain, J.4
Leo, O.5
ndris, F.6
-
27
-
-
3442900502
-
Depending on their maturation state, splenic dendritic cells induce the differentiation of CD4(+)T lymphocytes into memory and/or effector cells in vivo
-
de Heusch M, Oldenhove G, Urbain J, et al. Depending on their maturation state, splenic dendritic cells induce the differentiation of CD4(+)T lymphocytes into memory and/or effector cells in vivo. Eur J Immunol. 2004;34:1861-1869.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1861-1869
-
-
de Heusch, M.1
Oldenhove, G.2
Urbain, J.3
-
28
-
-
0031927264
-
CD28 co-stimulation stabilizes the expression of the CD40 ligand on T cells
-
Johnson-Leger C, Christensen J, Klaus GG. CD28 co-stimulation stabilizes the expression of the CD40 ligand on T cells. Int Immunol. 1998;10:1083-1091.
-
(1998)
Int Immunol
, vol.10
, pp. 1083-1091
-
-
Johnson-Leger, C.1
Christensen, J.2
Klaus, G.G.3
-
29
-
-
0035554935
-
Separable effector T cell populations specialized for B-cell help or tissue inflammation
-
Campbell DJ, Kim CH, Butcher EC. Separable effector T cell populations specialized for B-cell help or tissue inflammation. Nat Immunol. 2001;2: 876-881.
-
(2001)
Nat Immunol
, vol.2
, pp. 876-881
-
-
Campbell, D.J.1
Kim, C.H.2
Butcher, E.C.3
-
30
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva R, Yang XO, Martinez G, et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature. 2007;448:480-483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
-
31
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, Ivanov II, Spolski R, et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol. 2007;8:967-974.
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov II, S.R.2
-
32
-
-
0037159687
-
A critical role for IL-21 in regulating immunoglobulin production
-
Ozaki K, Spolski R, Feng CG, et al. A critical role for IL-21 in regulating immunoglobulin production. Science. 2002;298:1630-1634.
-
(2002)
Science
, vol.298
, pp. 1630-1634
-
-
Ozaki, K.1
Spolski, R.2
Feng, C.G.3
-
34
-
-
0036156077
-
Endogenous pro- and anti-inflammatory cytokines differentially regulate an in vivo humoral response to Streptococcus pneumoniae
-
Khan AQ, Shen Y, Wu ZQ, Wynn TA, Snapper CM. Endogenous pro- and anti-inflammatory cytokines differentially regulate an in vivo humoral response to Streptococcus pneumoniae. Infect Immun. 2002;70:749-761.
-
(2002)
Infect Immun
, vol.70
, pp. 749-761
-
-
Khan, A.Q.1
Shen, Y.2
Wu, Z.Q.3
Wynn, T.A.4
Snapper, C.M.5
-
36
-
-
40749123066
-
Autocrine regulation of IL-21 production in human T lymphocytes
-
Caprioli F, Sarra M, Caruso R, et al. Autocrine regulation of IL-21 production in human T lymphocytes. J Immunol. 2008;180:1800-1807.
-
(2008)
J Immunol
, vol.180
, pp. 1800-1807
-
-
Caprioli, F.1
Sarra, M.2
Caruso, R.3
-
37
-
-
38049101408
-
Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5+ T follicular helper cells
-
Bryant VL, Ma CS, Avery DT, et al. Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.J Immunol. 2007;179:8180-8190.
-
(2007)
J Immunol
, vol.179
, pp. 8180-8190
-
-
Bryant, V.L.1
Ma, C.S.2
Avery, D.T.3
-
38
-
-
41549131849
-
T follicular helper (T(FH)) cells in normal and dysregulated immune responses
-
King C, Tangye SG, Mackay CR. T follicular helper (T(FH)) cells in normal and dysregulated immune responses. Annu Rev Immunol. 2008;26:741-766.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 741-766
-
-
King, C.1
Tangye, S.G.2
Mackay, C.R.3
-
39
-
-
33847412873
-
IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo
-
Frohlich A, Marsland BJ, Sonderegger I, et al. IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood. 2007;109:2023-2031.
-
(2007)
Blood
, vol.109
, pp. 2023-2031
-
-
Frohlich, A.1
Marsland, B.J.2
Sonderegger, I.3
-
40
-
-
41549135632
-
The biological functions of T helper 17 cell effector cytokines in inflammation
-
Ouyang W, Kolls JK, Zheng Y. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity. 2008;28:454-467.
-
(2008)
Immunity
, vol.28
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
41
-
-
36849036211
-
-
Wei L, LaurenceA, Elias KM, O'Shea JJ. IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J Biol Chem. 2007;282:34605-34610.
-
Wei L, LaurenceA, Elias KM, O'Shea JJ. IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J Biol Chem. 2007;282:34605-34610.
-
-
-
-
42
-
-
0037037544
-
Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells
-
Wurster AL, Rodgers VL, Satoskar AR, et al. Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells. J Exp Med. 2002;196:969-977.
-
(2002)
J Exp Med
, vol.196
, pp. 969-977
-
-
Wurster, A.L.1
Rodgers, V.L.2
Satoskar, A.R.3
-
43
-
-
46749151286
-
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
-
Nurieva RI, Chung Y, Hwang D, et al. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity. 2008;29:138-149.
-
(2008)
Immunity
, vol.29
, pp. 138-149
-
-
Nurieva, R.I.1
Chung, Y.2
Hwang, D.3
-
44
-
-
46749115446
-
A fundamental role for interleukin-21 in the generation of T follicular helper cells
-
Vogelzang A, McGuire HM, Yu D, Sprent J, Mackay CR, King C. A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity. 2008;29:127-137.
-
(2008)
Immunity
, vol.29
, pp. 127-137
-
-
Vogelzang, A.1
McGuire, H.M.2
Yu, D.3
Sprent, J.4
Mackay, C.R.5
King, C.6
|