-
1
-
-
34648828532
-
AMP-activated/SNF1 protein kinases: Conserved guardians of cellular energy
-
DOI 10.1038/nrm2249, PII NRM2249
-
Hardie DG. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol 2007;8:774-85. (Pubitemid 47462132)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.10
, pp. 774-785
-
-
Hardie, D.G.1
-
2
-
-
50049105823
-
The regulation of AMP-activated protein kinase by upstream kinases
-
Carling D, Sanders MJ, Woods A. The regulation of AMP-activated protein kinase by upstream kinases. Int J Obes (Lond) 2008;32 (Suppl 4):S55-9
-
(2008)
Int J Obes (Lond)
, vol.32
, Issue.SUPPL. 4
-
-
Carling, D.1
Sanders, M.J.2
Woods, A.3
-
3
-
-
56449117024
-
AMPK: A metabolic gauge regulating whole-body energy homeostasis
-
Lage R, Dieguez C, Vidal-Puig A, Lopez M. AMPK: a metabolic gauge regulating whole-body energy homeostasis. Trends Mol Med 2008;14:539-49.
-
(2008)
Trends Mol Med
, vol.14
, pp. 539-549
-
-
Lage, R.1
Dieguez, C.2
Vidal-Puig, A.3
Lopez, M.4
-
4
-
-
63849301000
-
AMPK: Lessons from transgenic and knockout animals
-
Viollet B, Athea Y, Mounier R, Guigas B, Zarrinpashneh E, Horman S, Lantier L, Hebrard S, Devin-Leclerc J, Beauloye C, Foretz M, Andreelli F, et al. AMPK: Lessons from transgenic and knockout animals. Front Biosci 2009;14:19-44.
-
(2009)
Front Biosci
, vol.14
, pp. 19-44
-
-
Viollet, B.1
Athea, Y.2
Mounier, R.3
Guigas, B.4
Zarrinpashneh, E.5
Horman, S.6
Lantier, L.7
Hebrard, S.8
Devin-Leclerc, J.9
Beauloye, C.10
Foretz, M.11
Andreelli, F.12
-
5
-
-
33645123894
-
Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment
-
Cairns R, Papandreou I, Denko N. Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment. Mol Cancer Res 2006;4:61-70.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 61-70
-
-
Cairns, R.1
Papandreou, I.2
Denko, N.3
-
6
-
-
39749114978
-
Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability
-
Bristow RG, Hill RP. Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability. Nat Rev Cancer 2008;8:180-92.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 180-192
-
-
Bristow, R.G.1
Hill, R.P.2
-
7
-
-
33745840203
-
5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
-
DOI 10.1128/MCB.00166-06
-
Laderoute KR, Amin K, Calaoagan JM, Knapp M, Le T, Orduna J, Foretz M, Viollet B. 5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol Cell Biol 2006;26:5336-47. (Pubitemid 44036203)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.14
, pp. 5336-5347
-
-
Laderoute, K.R.1
Amin, K.2
Calaoagan, J.M.3
Knapp, M.4
Le, T.5
Orduna, J.6
Foretz, M.7
Viollet, B.8
-
8
-
-
33748570853
-
Semi-quantitative fluorescent PCR analysis identifies PRKAA1 on chromosome 5 as a potential candidate cancer gene of cervical cancer
-
DOI 10.1016/j.ygyno.2006.02.028, PII S0090825806002083
-
Huang FY, Chiu PM, Tam KF, Kwok YK, Lau ET, Tang MH, Ng TY, Liu VW, Cheung AN, Ngan HY. Semi-quantitative fluorescent PCR analysis identifies PRKAA1 on chromosome 5 as a potential candidate cancer gene of cervical cancer. Gynecol Oncol 2006;103:219-25. (Pubitemid 44374692)
-
(2006)
Gynecologic Oncology
, vol.103
, Issue.1
, pp. 219-225
-
-
Huang, F.Y.1
Chiu, P.M.2
Tam, K.F.3
Kwok, Y.K.Y.4
Lau, E.T.5
Tang, M.H.Y.6
Ng, T.Y.7
Liu, V.W.S.8
Cheung, A.N.Y.9
Ngan, H.Y.S.10
-
9
-
-
66449117931
-
AMP-activated protein kinase promotes human prostate cancer cell growth and survival
-
Park HU, Suy S, Danner M, Dailey V, Zhang Y, Li H, Hyduke DR, Collins BT, Gagnon G, Kallakury B, Kumar D, Brown ML, et al. AMP-activated protein kinase promotes human prostate cancer cell growth and survival. Mol Cancer Ther 2009;8:733-41.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 733-741
-
-
Park, H.U.1
Suy, S.2
Danner, M.3
Dailey, V.4
Zhang, Y.5
Li, H.6
Hyduke, D.R.7
Collins, B.T.8
Gagnon, G.9
Kallakury, B.10
Kumar, D.11
Brown, M.L.12
-
10
-
-
62449138276
-
Mitotic kinase dynamics of the active form of AMPK (phospho- AMPKalphaThr172) in human cancer cells
-
Vazquez-Martin A, Lopez-Bonet E, Oliveras-Ferraros C, Perez-Martinez MC, Bernado L, Menendez JA. Mitotic kinase dynamics of the active form of AMPK (phospho-AMPKalphaThr172) in human cancer cells. Cell Cycle 2009;8:788-91.
-
(2009)
Cell Cycle
, vol.8
, pp. 788-791
-
-
Vazquez-Martin, A.1
Lopez-Bonet, E.2
Oliveras-Ferraros, C.3
Perez-Martinez, M.C.4
Bernado, L.5
Menendez, J.A.6
-
11
-
-
70349883650
-
Histological evaluation of AMPK signalling in primary breast cancer
-
Hadad SM, Baker L, Quinlan PR, Robertson KE, Bray SE, Thomson G, Kellock D, Jordan LB, Purdie CA, Hardie DG, Fleming S, Thompson AM. Histological evaluation of AMPK signalling in primary breast cancer. BMC Cancer 2009;9:307.
-
(2009)
BMC Cancer
, vol.9
, pp. 307
-
-
Hadad, S.M.1
Baker, L.2
Quinlan, P.R.3
Robertson, K.E.4
Bray, S.E.5
Thomson, G.6
Kellock, D.7
Jordan, L.B.8
Purdie, C.A.9
Hardie, D.G.10
Fleming, S.11
Thompson, A.M.12
-
12
-
-
0033950187
-
Evaluation of ENU-induced gliomas in rats: Nomenclature, immunochemistry, and malignancy
-
Zook BC, Simmens SJ, Jones RV. Evaluation of ENU-induced gliomas in rats: nomenclature, immunochemistry, and malignancy. Toxicol Pathol 2000;28:193-201. (Pubitemid 30078222)
-
(2000)
Toxicologic Pathology
, vol.28
, Issue.1
, pp. 193-201
-
-
Zook, B.C.1
Simmens, S.J.2
Jones, R.V.3
-
13
-
-
33646494666
-
Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea
-
Jang T, Savarese T, Low HP, Kim S, Vogel H, Lapointe D, Duong T, Litofsky NS, Weimann JM, Ross AH, Recht L. Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. Am J Pathol 2006;168:1676-85.
-
(2006)
Am J Pathol
, vol.168
, pp. 1676-1685
-
-
Jang, T.1
Savarese, T.2
Low, H.P.3
Kim, S.4
Vogel, H.5
Lapointe, D.6
Duong, T.7
Litofsky, N.S.8
Weimann, J.M.9
Ross, A.H.10
Recht, L.11
-
14
-
-
33747178432
-
Hypoxia in the tumorigenesis of gliomas and as a potential target for therapeutic measures
-
Jensen RL Hypoxia in the tumorigenesis of gliomas and as a potential target for therapeutic measures. Neurosurg Focus 20:E24, 2006.
-
(2006)
Neurosurg Focus
, vol.20
-
-
Jensen, R.L.1
-
15
-
-
33746696738
-
'Pseudopalisading' necrosis in glioblastoma: A familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis
-
Rong Y, Durden DL, Van Meir EG, Brat DJ. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. J Neuropathol Exp Neurol 2006;65:529-39.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 529-539
-
-
Rong, Y.1
Durden, D.L.2
Van Meir, E.G.3
Brat, D.J.4
-
17
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009;324:1029-33.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
18
-
-
36849071229
-
Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake
-
DOI 10.1073/pnas.0708385104
-
Gao S, Kinzig KP, Aja S, Scott KA, Keung W, Kelly S, Strynadka K, Chohnan S, Smith WW, Tamashiro KL, Ladenheim EE, Ronnett GV, et al. Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake. Proc Natl Acad Sci USA 2007;104:17358-63. (Pubitemid 350219847)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.44
, pp. 17358-17363
-
-
Gao, S.1
Kinzig, K.P.2
Aja, S.3
Scott, K.A.4
Keung, W.5
Kelly, S.6
Strynadka, K.7
Chohnan, S.8
Smith, W.W.9
Tamashiro, K.L.K.10
Ladenheim, E.E.11
Ronnett, G.V.12
Tu, Y.13
Birnbaum, M.J.14
Lopaschuk, G.D.15
Moran, T.H.16
-
19
-
-
13844281729
-
Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure
-
Savarese TM, Jang T, Low HP, Salmonsen R, Litofsky NS, Matuasevic Z, Ross AH, Recht LD. Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure. J Neurosurg 2005;102:98-108. (Pubitemid 43186702)
-
(2005)
Journal of Neurosurgery
, vol.102
, Issue.1
, pp. 98-108
-
-
Savarese, T.M.1
Jang, T.2
Hoi, P.L.3
Salmonsen, R.4
Litofsky, N.S.5
Matijasevic, Z.6
Ross, A.H.7
Recht, L.D.8
-
20
-
-
0031056475
-
TrkA expression decreases the in vivo aggressiveness of C6 glioma cells
-
Lachyankar MB, Ross AH, Litofsky NS, Condon PJ, Quesenberry PJ, Recht LD. TrkA expression decreases the in vivo aggressiveness of C6 glioma cells. Cancer Res 1997;57:532-6. (Pubitemid 27081675)
-
(1997)
Cancer Research
, vol.57
, Issue.3
, pp. 532-536
-
-
Lachyankar, M.B.1
Ross, A.H.2
Scott, L.N.3
Condon, P.J.4
Quesenberry, P.J.5
Recht, L.D.6
-
21
-
-
0036864358
-
Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase
-
DOI 10.1042/BST0301064
-
Hardie DG, Pan DA. Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase. Biochem Soc Trans 2002;30:1064-70. (Pubitemid 36002407)
-
(2002)
Biochemical Society Transactions
, vol.30
, Issue.6
, pp. 1064-1070
-
-
Hardie, D.G.1
Pan, D.A.2
-
22
-
-
0028092988
-
Critical phosphorylation sites for acetyl-CoA carboxylase activity
-
Ha J, Daniel S, Broyles SS, Kim KH. Critical phosphorylation sites for acetyl-CoA carboxylase activity. J Biol Chem 1994;269:22162-8. (Pubitemid 24282143)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.35
, pp. 22162-22168
-
-
Ha, J.1
Daniel, S.2
Broyles, S.S.3
Kim, K.-H.4
-
23
-
-
0030939116
-
Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms
-
Abu-Elheiga L, Almarza-Ortega DB, Baldini A, Wakil SJ. Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms. J Biol Chem 1997;272:10669-77.
-
(1997)
J Biol Chem
, vol.272
, pp. 10669-10677
-
-
Abu-Elheiga, L.1
Almarza-Ortega, D.B.2
Baldini, A.3
Wakil, S.J.4
-
24
-
-
0014430979
-
Differentiated rat glial cell strain in tissue culture
-
Benda P, Lightbody J, Sato G, Levine L, Sweet W. Differentiated rat glial cell strain in tissue culture. Science 1968;161:370-1.
-
(1968)
Science
, vol.161
, pp. 370-371
-
-
Benda, P.1
Lightbody, J.2
Sato, G.3
Levine, L.4
Sweet, W.5
-
25
-
-
1842524041
-
Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis
-
DOI 10.1016/j.nbd.2003.11.016, PII S0969996103002511
-
Jang T, Litofsky NS, Smith TW, Ross AH, Recht LD. Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis. Neurobiol Dis 2004;15:544-52. (Pubitemid 38429969)
-
(2004)
Neurobiology of Disease
, vol.15
, Issue.3
, pp. 544-552
-
-
Jang, T.1
Litofsky, N.S.2
Smith, T.W.3
Ross, A.H.4
Recht, L.D.5
-
26
-
-
0017092790
-
The origin of experimental brain tumours: A sequential study
-
Lantos PL, Cox DJ. The origin of experimental brain tumours: a sequential study. Experientia 1976;32:1467-1468.
-
(1976)
Experientia
, vol.32
, pp. 1467-1468
-
-
Lantos, P.L.1
Cox, D.J.2
-
27
-
-
0018874565
-
Experimental brain tumors by transplacental ENU. Multifactorial study of the latency period
-
Schiffer D, Giordana MT, Mauro A, Racagni G, Bruno F, Pezzotta S, Paoletti P. Experimental brain tumors by transplacental ENU. Multifactorial study of the latency period. Acta Neuropathol 1980;49:117-22.
-
(1980)
Acta Neuropathol
, vol.49
, pp. 117-122
-
-
Schiffer, D.1
Giordana, M.T.2
Mauro, A.3
Racagni, G.4
Bruno, F.5
Pezzotta, S.6
Paoletti, P.7
-
28
-
-
0024435610
-
A sequential ultrastructural and histoautoradiographic study of early neoplastic lesions in ethylnitrosourea-induced rat glioma
-
Ikeda T, Mashimoto H, Iwasaki K, Shimokawa I, Matsuo T. A sequential ultrastructural and histoautoradiographic study of early neoplastic lesions in ethylnitrosourea-induced rat glioma. Acta Pathol Jpn 1989;39:487-95. (Pubitemid 19246265)
-
(1989)
Acta Pathologica Japonica
, vol.39
, Issue.8
, pp. 487-495
-
-
Ikeda, T.1
Mashimoto, H.2
Iwasaki, K.3
Shimokawa, I.4
Matsuo, T.5
-
29
-
-
0034652297
-
The subcellular localization of acetyl-CoA carboxylase 2
-
DOI 10.1073/pnas.97.4.1444
-
Abu-Elheiga L, Brinkley WR, Zhong L, Chirala SS, Woldegiorgis G, Wakil SJ. The subcellular localization of acetyl-CoA carboxylase 2. Proc Natl Acad Sci U S A 2000;97:1444-9. (Pubitemid 30118460)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.4
, pp. 1444-1449
-
-
Abu-Elheiga, L.1
Brinkley, W.R.2
Zhong, L.3
Chirala, S.S.4
Woldegiorgis, G.5
Wakil, S.J.6
-
30
-
-
34147152841
-
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
-
DOI 10.1042/BJ20061520
-
Sanders MJ, Grondin PO, Hegarty BD, Snowden MA, Carling D. Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade. Biochem J 2007;403:139-48. (Pubitemid 46569875)
-
(2007)
Biochemical Journal
, vol.403
, Issue.1
, pp. 139-148
-
-
Sanders, M.J.1
Grondin, P.O.2
Hegarty, B.D.3
Snowden, M.A.4
Carling, D.5
-
31
-
-
68449094064
-
The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis
-
Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA. The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis. Cell Cycle 2009;8:2385-98.
-
(2009)
Cell Cycle
, vol.8
, pp. 2385-2398
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Menendez, J.A.3
-
32
-
-
52149101812
-
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
-
Papandreou I, Lim AL, Laderoute K, Denko NC. Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L. Cell Death Differ 2008;15:1572-81.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1572-1581
-
-
Papandreou, I.1
Lim, A.L.2
Laderoute, K.3
Denko, N.C.4
-
34
-
-
33745199458
-
Developing a head for energy sensing: AMP-activated protein kinase as a multifunctional metabolic sensor in the brain
-
DOI 10.1113/jphysiol.2006.110122
-
Ramamurthy S, Ronnett GV. Developing a head for energy sensing: AMP-activated protein kinase as a multifunctional metabolic sensor in the brain. J Physiol 2006;574:85-93. (Pubitemid 43905799)
-
(2006)
Journal of Physiology
, vol.574
, Issue.1
, pp. 85-93
-
-
Ramamurthy, S.1
Ronnett, G.V.2
-
35
-
-
49749107589
-
Role of hypothalamic AMP-kinase in food intake regulation
-
Minokoshi Y, Shiuchi T, Lee S, Suzuki A, Okamoto S. Role of hypothalamic AMP-kinase in food intake regulation. Nutrition 2008;24:786-90.
-
(2008)
Nutrition
, vol.24
, pp. 786-790
-
-
Minokoshi, Y.1
Shiuchi, T.2
Lee, S.3
Suzuki, A.4
Okamoto, S.5
-
36
-
-
49649122302
-
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
-
Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschop MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, et al. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature 2008;454:846-51.
-
(2008)
Nature
, vol.454
, pp. 846-851
-
-
Andrews, Z.B.1
Liu, Z.W.2
Walllingford, N.3
Erion, D.M.4
Borok, E.5
Friedman, J.M.6
Tschop, M.H.7
Shanabrough, M.8
Cline, G.9
Shulman, G.I.10
Coppola, A.11
Gao, X.B.12
-
37
-
-
39149107803
-
Mechanisms and Functional Implications of Adult Neurogenesis
-
DOI 10.1016/j.cell.2008.01.033, PII S0092867408001347
-
Zhao C, Deng W, Gage FH. Mechanisms and functional implications of adult neurogenesis. Cell 2008;132:645-60. (Pubitemid 351253687)
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 645-660
-
-
Zhao, C.1
Deng, W.2
Gage, F.H.3
-
38
-
-
41849124536
-
A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection: Laboratory investigation
-
DOI 10.3171/JNS/2008/108/4/0782
-
Jang T, Sathy B, Hsu YH, Merchant M, Recht B, Chang C, Recht L. A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection. J Neurosurg 2008;108:782-90. (Pubitemid 351498975)
-
(2008)
Journal of Neurosurgery
, vol.108
, Issue.4
, pp. 782-790
-
-
Jang, T.1
Sathy, B.2
Hsu, Y.-H.3
Merchant, M.4
Recht, B.5
Chang, C.6
Recht, L.7
-
39
-
-
61449106744
-
AMPK and the biochemistry of exercise: Implications for human health and disease
-
Richter EA, Ruderman NB. AMPK and the biochemistry of exercise: implications for human health and disease. Biochem J 2009;418:261-75.
-
(2009)
Biochem J
, vol.418
, pp. 261-275
-
-
Richter, E.A.1
Ruderman, N.B.2
-
40
-
-
33745213627
-
AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer
-
DOI 10.1113/jphysiol.2006.108324
-
Motoshima H, Goldstein BJ, Igata M, Araki E. AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer. J Physiol 2006;574:63-71. (Pubitemid 43905797)
-
(2006)
Journal of Physiology
, vol.574
, Issue.1
, pp. 63-71
-
-
Motoshima, H.1
Goldstein, B.J.2
Igata, M.3
Araki, E.4
-
41
-
-
33947250696
-
kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
-
DOI 10.1038/ncb1537, PII NCB1537
-
Liang J, Shao SH, Xu ZX, Hennessy B, Ding Z, Larrea M, Kondo S, Dumont DJ, Gutterman JU, Walker CL, Slingerland JM, Mills GB. The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat Cell Biol 2007;9:218-24. (Pubitemid 46420865)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.2
, pp. 218-224
-
-
Liang, J.1
Shao, S.H.2
Xu, Z.-X.3
Hennessy, B.4
Ding, Z.5
Larrea, M.6
Kondo, S.7
Dumont, D.J.8
Gutterman, J.U.9
Walker, C.L.10
Slingerland, J.M.11
Mills, G.B.12
-
42
-
-
42949152052
-
Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress
-
Okoshi R, Ozaki T, Yamamoto H, Ando K, Koida N, Ono S, Koda T, Kamijo T, Nakagawara A, Kizaki H. Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress. J Biol Chem 2008;283:3979-87.
-
(2008)
J Biol Chem
, vol.283
, pp. 3979-3987
-
-
Okoshi, R.1
Ozaki, T.2
Yamamoto, H.3
Ando, K.4
Koida, N.5
Ono, S.6
Koda, T.7
Kamijo, T.8
Nakagawara, A.9
Kizaki, H.10
-
44
-
-
50849113768
-
Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain
-
Mirzadeh Z, Merkle FT, Soriano-Navarro M, Garcia-Verdugo JM, Alvarez-Buylla A. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 2008;3:265-278.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 265-278
-
-
Mirzadeh, Z.1
Merkle, F.T.2
Soriano-Navarro, M.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
45
-
-
33645993596
-
Regulation of acetyl-CoA carboxylase
-
Brownsey RW, Boone AN, Elliott JE, Kulpa JE, Lee WM. Regulation of acetyl-CoA carboxylase. Biochem Soc Trans 2006;34:223-7.
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 223-227
-
-
Brownsey, R.W.1
Boone, A.N.2
Elliott, J.E.3
Kulpa, J.E.4
Lee, W.M.5
-
46
-
-
34147174943
-
Changes in the expression of hypothalamic lipid sensing genes in rat model of intrauterine growth retardation (IUGR)
-
DOI 10.1203/pdr.0b013e3180332d4e
-
Puglianiello A, Germani D, Antignani S, Tomba GS, Cianfarani S. Changes in the expression of hypothalamic lipid sensing genes in rat model of intrauterine growth retardation (IUGR). Pediatr Res 2007;61:433-7. (Pubitemid 46569296)
-
(2007)
Pediatric Research
, vol.61
, Issue.4
, pp. 433-437
-
-
Puglianiello, A.1
Germani, D.2
Antignani, S.3
Tomba, G.S.4
Cianfarani, S.5
-
47
-
-
40949142209
-
The role of hypoxia-inducible factors in tumorigenesis
-
DOI 10.1038/cdd.2008.21, PII CDD200821, The biology of Hypoxia-inducible factors
-
Rankin EB, Giaccia AJ. The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ 2008;15:678-85. (Pubitemid 351405072)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.4
, pp. 678-685
-
-
Rankin, E.B.1
Giaccia, A.J.2
-
48
-
-
33646247392
-
AMP-dependent protein kinase alpha 2 isoform promotes hypoxia-induced VEGF expression in human glioblastoma
-
Neurath KM, Keough MP, Mikkelsen T, Claffey KP. AMP-dependent protein kinase alpha 2 isoform promotes hypoxia-induced VEGF expression in human glioblastoma. Glia 2006;53:733-43.
-
(2006)
Glia
, vol.53
, pp. 733-743
-
-
Neurath, K.M.1
Keough, M.P.2
Mikkelsen, T.3
Claffey, K.P.4
-
49
-
-
0036048395
-
Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5
-
DOI 10.1016/S0076-6879(02)52003-6, 1, Redox Cell Biology and Genetics Part A
-
Koch CJ. Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5. Methods Enzymol 2002;352:3-31. (Pubitemid 41103167)
-
(2002)
Methods in Enzymology
, vol.352
, pp. 3-31
-
-
Koch, C.J.1
-
50
-
-
34547121206
-
Hypoxia in cancer: Significance and impact on clinical outcome
-
DOI 10.1007/s10555-007-9055-1, Special issue on Hypoxia and Cancer, Guest Editor: Gregg L. Semenza
-
Vaupel P, Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 2007;26:225-39. (Pubitemid 47101660)
-
(2007)
Cancer and Metastasis Reviews
, vol.26
, Issue.2
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
51
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008;132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
52
-
-
67549131188
-
Energy homeostasis and cancer prevention: The AMP-activated protein kinase
-
Fay JR, Steele V, Crowell JA. Energy homeostasis and cancer prevention: the AMP-activated protein kinase. Cancer Prev Res (Phila Pa) 2009;2:301-9.
-
(2009)
Cancer Prev Res (Phila Pa)
, vol.2
, pp. 301-309
-
-
Fay, J.R.1
Steele, V.2
Crowell, J.A.3
-
53
-
-
0037026608
-
Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation
-
Kato K, Ogura T, Kishimoto A, Minegishi Y, Nakajima N, Miyazaki M, Esumi H. Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation. Oncogene 2002;21:6082-90.
-
(2002)
Oncogene
, vol.21
, pp. 6082-6090
-
-
Kato, K.1
Ogura, T.2
Kishimoto, A.3
Minegishi, Y.4
Nakajima, N.5
Miyazaki, M.6
Esumi, H.7
-
54
-
-
24744451416
-
Involvement of transforming growth factor-beta1 signaling in hypoxia-induced tolerance to glucose starvation
-
DOI 10.1074/jbc.M503714200
-
Suzuki A, Kusakai GI, Shimojo Y, Chen J, Ogura T, Kobayashi M, Esumi H. Involvement of TGF-beta1 signaling in hypoxia-induced tolerance to glucose starvation. J Biol Chem 2005;280:31557-63. (Pubitemid 41291899)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.36
, pp. 31557-31563
-
-
Suzuki, A.1
Kusakai, G.-I.2
Shimojo, Y.3
Chen, J.4
Ogura, T.5
Kobayashi, M.6
Esumi, H.7
-
55
-
-
42949088694
-
Inhibition of AMP-activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53
-
Kim HS, Hwang JT, Yun H, Chi SG, Lee SJ, Kang I, Yoon KS, Choe WJ, Kim SS, Ha J. Inhibition of AMP-activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53. J Biol Chem 2008;283:3731-42.
-
(2008)
J Biol Chem
, vol.283
, pp. 3731-3742
-
-
Kim, H.S.1
Hwang, J.T.2
Yun, H.3
Chi, S.G.4
Lee, S.J.5
Kang, I.6
Yoon, K.S.7
Choe, W.J.8
Kim, S.S.9
Ha, J.10
-
56
-
-
34548044509
-
Synergistic up-regulation of Hexokinase-2, glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia
-
DOI 10.1016/j.yexcr.2007.06.013, PII S0014482707002856
-
Natsuizaka M, Ozasa M, Darmanin S, Miyamoto M, Kondo S, Kamada S, Shindoh M, Higashino F, Suhara W, Koide H, Aita K, Nakagawa K, et al. Synergistic up-regulation of hexokinase-2, glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia. Exp Cell Res 2007;313:3337-48. (Pubitemid 47284060)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.15
, pp. 3337-3348
-
-
Natsuizaka, M.1
Ozasa, M.2
Darmanin, S.3
Miyamoto, M.4
Kondo, S.5
Kamada, S.6
Shindoh, M.7
Higashino, F.8
Suhara, W.9
Koide, H.10
Aita, K.11
Nakagawa, K.12
Kondo, T.13
Asaka, M.14
Okada, F.15
Kobayashi, M.16
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