Synergistic up-regulation of Hexokinase-2, glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia

Experimental Cell Research

Volumn 313, Issue 15, 2007, Pages 3337-3348

  Natsuizaka, Mitsuteru ^a   Ozasa, Mariko ^a   Darmanin, Stephanie ^b   Miyamoto, Masaki ^a   Kondo, Satoshi ^a   Kamada, Suguru ^b   Shindoh, Masanobu ^b   Higashino, Fumihiro ^b   Suhara, Wakako ^c   Koide, Hideyuki ^c   Aita, Kiyoshi ^c   Nakagawa, Koji ^c   Kondo, Takeshi ^a   Asaka, Masahiro ^a   Okada, Futoshi ^d   Kobayashi, Masanobu ^a,b,c  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c Oncorex Inc   (Japan)

^d YAMAGATA UNIVERSITY   (Japan)

Author keywords

AMPK; Glucose deprivation; HIF; Hypoxia

Indexed keywords

ADENYLATE KINASE; ADRENOMEDULLIN; ENZYME ANTIBODY; ENZYME INHIBITOR; GLUCOSE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 3; HEXOKINASE; HEXOKINASE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; BIOACCUMULATION; CANCER CELL; CARCINOGENESIS; CELL STRESS; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOHISTOCHEMISTRY; MOLECULAR BIOLOGY; PANCREAS CANCER; PANCREAS CELL; PRIORITY JOURNAL; UPREGULATION;

EID: 34548044509     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.06.013     Document Type: Article

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