-
1
-
-
0025932984
-
Apoptosis: mechanisms and roles in pathology
-
Arends M.J., Wyllie A.H. Apoptosis: mechanisms and roles in pathology. Int. Rev. Exp. Pathol. 1991, 32:223-254.
-
(1991)
Int. Rev. Exp. Pathol.
, vol.32
, pp. 223-254
-
-
Arends, M.J.1
Wyllie, A.H.2
-
2
-
-
0842281645
-
Cell death: critical control points
-
Danial N.N., Korsmeyer S.J. Cell death: critical control points. Cell 2004, 116:205-219.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
3
-
-
0030931876
-
Caspases: the executioners of apoptosis
-
Cohen G.M. Caspases: the executioners of apoptosis. Biochem. J. 1997, 326(Pt 1):1-16.
-
(1997)
Biochem. J.
, vol.326
, Issue.PART 1
, pp. 1-16
-
-
Cohen, G.M.1
-
4
-
-
0034630330
-
Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis
-
Bratton S.B., MacFarlane M., Cain K., Cohen G.M. Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis. Exp. Cell Res. 2000, 256:27-33.
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 27-33
-
-
Bratton, S.B.1
MacFarlane, M.2
Cain, K.3
Cohen, G.M.4
-
5
-
-
0036598992
-
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
-
Ashkenazi A. Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat. Rev. Cancer 2002, 2:420-430.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 420-430
-
-
Ashkenazi, A.1
-
6
-
-
3442886811
-
The pathophysiology of mitochondrial cell death
-
Green D.R., Kroemer G. The pathophysiology of mitochondrial cell death. Science 2004, 305:626-629.
-
(2004)
Science
, vol.305
, pp. 626-629
-
-
Green, D.R.1
Kroemer, G.2
-
7
-
-
0036478928
-
The Apaf-1 apoptosome: a large caspase-activating complex
-
Cain K., Bratton S.B., Cohen G.M. The Apaf-1 apoptosome: a large caspase-activating complex. Biochimie 2002, 84:203-214.
-
(2002)
Biochimie
, vol.84
, pp. 203-214
-
-
Cain, K.1
Bratton, S.B.2
Cohen, G.M.3
-
8
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis J.M., Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 2001, 81:807-869.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
9
-
-
0031044561
-
MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?
-
Fanger G.R., Gerwins P., Widmann C., Jarpe M.B., Johnson G.L. MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?. Curr. Opin. Genet. Dev. 1997, 7:67-74.
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 67-74
-
-
Fanger, G.R.1
Gerwins, P.2
Widmann, C.3
Jarpe, M.B.4
Johnson, G.L.5
-
10
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis R.J. Signal transduction by the JNK group of MAP kinases. Cell 2000, 103:239-252.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
11
-
-
0034164455
-
(review)
-
Chen Y.R., Tan T.H. The c-Jun N-terminal kinase pathway and apoptotic signaling. Int. J. Oncol. 2000, 16:651-662.
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 651-662
-
-
Chen, Y.R.1
Tan, T.H.2
-
12
-
-
0034658384
-
JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation
-
MacFarlane M., Cohen G.M., Dickens M. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation. Biochem. J. 2000, 348(Pt 1):93-101.
-
(2000)
Biochem. J.
, vol.348
, Issue.PART 1
, pp. 93-101
-
-
MacFarlane, M.1
Cohen, G.M.2
Dickens, M.3
-
13
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z., Dickens M., Raingeaud J., Davis R.J., Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995, 270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
14
-
-
0035033952
-
Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38
-
Harper S.J., LoGrasso P. Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38. Cell. Signal. 2001, 13:299-310.
-
(2001)
Cell. Signal.
, vol.13
, pp. 299-310
-
-
Harper, S.J.1
LoGrasso, P.2
-
15
-
-
0036269755
-
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase
-
Lei K., Nimnual A., Zong W.X., Kennedy N.J., Flavell R.A., Thompson C.B., Bar-Sagi D., Davis R.J. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol. Cell. Biol. 2002, 22:4929-4942.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4929-4942
-
-
Lei, K.1
Nimnual, A.2
Zong, W.X.3
Kennedy, N.J.4
Flavell, R.A.5
Thompson, C.B.6
Bar-Sagi, D.7
Davis, R.J.8
-
16
-
-
13944262137
-
JNK is associated with Bcl-2 and PP1 in mitochondria: paclitaxel induces its activation and its association with the phosphorylated form of Bcl-2
-
Brichese L., Cazettes G., Valette A. JNK is associated with Bcl-2 and PP1 in mitochondria: paclitaxel induces its activation and its association with the phosphorylated form of Bcl-2. Cell Cycle 2004, 3:1312-1319.
-
(2004)
Cell Cycle
, vol.3
, pp. 1312-1319
-
-
Brichese, L.1
Cazettes, G.2
Valette, A.3
-
17
-
-
0034614658
-
Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage
-
Kharbanda S., Saxena S., Yoshida K., Pandey P., Kaneki M., Wang Q., Cheng K., Chen Y.N., Campbell A., Sudha T., Yuan Z.M., Narula J., Weichselbaum R., Nalin C., Kufe D. Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage. J. Biol. Chem. 2000, 275:322-327.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 322-327
-
-
Kharbanda, S.1
Saxena, S.2
Yoshida, K.3
Pandey, P.4
Kaneki, M.5
Wang, Q.6
Cheng, K.7
Chen, Y.N.8
Campbell, A.9
Sudha, T.10
Yuan, Z.M.11
Narula, J.12
Weichselbaum, R.13
Nalin, C.14
Kufe, D.15
-
18
-
-
0141953270
-
A JNK-dependent pathway is required for TNFalpha-induced apoptosis
-
Deng Y., Ren X., Yang L., Lin Y., Wu X. A JNK-dependent pathway is required for TNFalpha-induced apoptosis. Cell 2003, 115:61-70.
-
(2003)
Cell
, vol.115
, pp. 61-70
-
-
Deng, Y.1
Ren, X.2
Yang, L.3
Lin, Y.4
Wu, X.5
-
19
-
-
0034607702
-
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
-
Tournier C., Hess P., Yang D.D., Xu J., Turner T.K., Nimnual A., Bar-Sagi D., Jones S.N., Flavell R.A., Davis R.J. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 2000, 288:870-874.
-
(2000)
Science
, vol.288
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
Xu, J.4
Turner, T.K.5
Nimnual, A.6
Bar-Sagi, D.7
Jones, S.N.8
Flavell, R.A.9
Davis, R.J.10
-
20
-
-
13444301318
-
Specific pathophysiological functions of JNK isoforms in the brain
-
Brecht S., Kirchhof R., Chromik A., Willesen M., Nicolaus T., Raivich G., Wessig J., Waetzig V., Goetz M., Claussen M., Pearse D., Kuan C.Y., Vaudano E., Behrens A., Wagner E., Flavell R.A., Davis R.J., Herdegen T. Specific pathophysiological functions of JNK isoforms in the brain. Eur. J. Neurosci. 2005, 21:363-377.
-
(2005)
Eur. J. Neurosci.
, vol.21
, pp. 363-377
-
-
Brecht, S.1
Kirchhof, R.2
Chromik, A.3
Willesen, M.4
Nicolaus, T.5
Raivich, G.6
Wessig, J.7
Waetzig, V.8
Goetz, M.9
Claussen, M.10
Pearse, D.11
Kuan, C.Y.12
Vaudano, E.13
Behrens, A.14
Wagner, E.15
Flavell, R.A.16
Davis, R.J.17
Herdegen, T.18
-
21
-
-
33746379603
-
JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells
-
Kim B.J., Ryu S.W., Song B.J. JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. J. Biol. Chem. 2006, 281:21256-21265.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 21256-21265
-
-
Kim, B.J.1
Ryu, S.W.2
Song, B.J.3
-
22
-
-
0037418238
-
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
-
Lei K., Davis R.J. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc. Natl Acad. Sci. USA 2003, 100:2432-2437.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 2432-2437
-
-
Lei, K.1
Davis, R.J.2
-
23
-
-
0032724021
-
Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2
-
Sabapathy K., Jochum W., Hochedlinger K., Chang L., Karin M., Wagner E.F. Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2. Mech. Dev. 1999, 89:115-124.
-
(1999)
Mech. Dev.
, vol.89
, pp. 115-124
-
-
Sabapathy, K.1
Jochum, W.2
Hochedlinger, K.3
Chang, L.4
Karin, M.5
Wagner, E.F.6
-
24
-
-
0034194714
-
Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase
-
Almeida E.A., Ilic D., Han Q., Hauck C.R., Jin F., Kawakatsu H., Schlaepfer D.D., Damsky C.H. Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase. J. Cell Biol. 2000, 149:741-754.
-
(2000)
J. Cell Biol.
, vol.149
, pp. 741-754
-
-
Almeida, E.A.1
Ilic, D.2
Han, Q.3
Hauck, C.R.4
Jin, F.5
Kawakatsu, H.6
Schlaepfer, D.D.7
Damsky, C.H.8
-
25
-
-
0033969883
-
Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner
-
Potapova O., Gorospe M., Dougherty R.H., Dean N.M., Gaarde W.A., Holbrook N.J. Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner. Mol. Cell. Biol. 2000, 20:1713-1722.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1713-1722
-
-
Potapova, O.1
Gorospe, M.2
Dougherty, R.H.3
Dean, N.M.4
Gaarde, W.A.5
Holbrook, N.J.6
-
26
-
-
0038433303
-
JunD mediates survival signaling by the JNK signal transduction pathway
-
Lamb J.A., Ventura J.J., Hess P., Flavell R.A., Davis R.J. JunD mediates survival signaling by the JNK signal transduction pathway. Mol. Cell 2003, 11:1479-1489.
-
(2003)
Mol. Cell
, vol.11
, pp. 1479-1489
-
-
Lamb, J.A.1
Ventura, J.J.2
Hess, P.3
Flavell, R.A.4
Davis, R.J.5
-
27
-
-
1242316958
-
JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD
-
Yu C., Minemoto Y., Zhang J., Liu J., Tang F., Bui T.N., Xiang J., Lin A. JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. Mol. Cell 2004, 13:329-340.
-
(2004)
Mol. Cell
, vol.13
, pp. 329-340
-
-
Yu, C.1
Minemoto, Y.2
Zhang, J.3
Liu, J.4
Tang, F.5
Bui, T.N.6
Xiang, J.7
Lin, A.8
-
28
-
-
23744437996
-
C-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells
-
Gururajan M., Chui R., Karuppannan A.K., Ke J., Jennings C.D., Bondada S. c-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells. Blood 2005, 106:1382-1391.
-
(2005)
Blood
, vol.106
, pp. 1382-1391
-
-
Gururajan, M.1
Chui, R.2
Karuppannan, A.K.3
Ke, J.4
Jennings, C.D.5
Bondada, S.6
-
29
-
-
0035808769
-
C-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation
-
Sabapathy K., Kallunki T., David J.P., Graef I., Karin M., Wagner E.F. c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation. J. Exp. Med. 2001, 193:317-328.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 317-328
-
-
Sabapathy, K.1
Kallunki, T.2
David, J.P.3
Graef, I.4
Karin, M.5
Wagner, E.F.6
-
30
-
-
0036730122
-
Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts
-
Hess P., Pihan G., Sawyers C.L., Flavell R.A., Davis R.J. Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts. Nat. Genet. 2002, 32:201-205.
-
(2002)
Nat. Genet.
, vol.32
, pp. 201-205
-
-
Hess, P.1
Pihan, G.2
Sawyers, C.L.3
Flavell, R.A.4
Davis, R.J.5
-
31
-
-
0030826412
-
A cytoplasmic inhibitor of the JNK signal transduction pathway
-
Dickens M., Rogers J.S., Cavanagh J., Raitano A., Xia Z., Halpern J.R., Greenberg M.E., Sawyers C.L., Davis R.J. A cytoplasmic inhibitor of the JNK signal transduction pathway. Science 1997, 277:693-696.
-
(1997)
Science
, vol.277
, pp. 693-696
-
-
Dickens, M.1
Rogers, J.S.2
Cavanagh, J.3
Raitano, A.4
Xia, Z.5
Halpern, J.R.6
Greenberg, M.E.7
Sawyers, C.L.8
Davis, R.J.9
-
32
-
-
0032825497
-
The JIP group of mitogen-activated protein kinase scaffold proteins
-
Yasuda J., Whitmarsh A.J., Cavanagh J., Sharma M., Davis R.J. The JIP group of mitogen-activated protein kinase scaffold proteins. Mol. Cell. Biol. 1999, 19:7245-7254.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7245-7254
-
-
Yasuda, J.1
Whitmarsh, A.J.2
Cavanagh, J.3
Sharma, M.4
Davis, R.J.5
-
33
-
-
0033971177
-
Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3
-
Kelkar N., Gupta S., Dickens M., Davis R.J. Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. Mol. Cell. Biol. 2000, 20:1030-1043.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1030-1043
-
-
Kelkar, N.1
Gupta, S.2
Dickens, M.3
Davis, R.J.4
-
34
-
-
0344393408
-
Regulation of MAP kinase signaling modules by scaffold proteins in mammals
-
Morrison D.K., Davis R.J. Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu. Rev. Cell Dev. Biol. 2003, 19:91-118.
-
(2003)
Annu. Rev. Cell Dev. Biol.
, vol.19
, pp. 91-118
-
-
Morrison, D.K.1
Davis, R.J.2
-
35
-
-
0031915453
-
IB1, a JIP-1-related nuclear protein present in insulin-secreting cells
-
Bonny C., Nicod P., Waeber G. IB1, a JIP-1-related nuclear protein present in insulin-secreting cells. J. Biol. Chem. 1998, 273:1843-1846.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1843-1846
-
-
Bonny, C.1
Nicod, P.2
Waeber, G.3
-
36
-
-
0342858815
-
CDNA cloning and mapping of a novel islet-brain/JNK-interacting protein
-
Negri S., Oberson A., Steinmann M., Sauser C., Nicod P., Waeber G., Schorderet D.F., Bonny C. cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein. Genomics 2000, 64:324-330.
-
(2000)
Genomics
, vol.64
, pp. 324-330
-
-
Negri, S.1
Oberson, A.2
Steinmann, M.3
Sauser, C.4
Nicod, P.5
Waeber, G.6
Schorderet, D.F.7
Bonny, C.8
-
37
-
-
0032694245
-
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway
-
Ito M., Yoshioka K., Akechi M., Yamashita S., Takamatsu N., Sugiyama K., Hibi M., Nakabeppu Y., Shiba T., Yamamoto K.I. JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway. Mol. Cell. Biol. 1999, 19:7539-7548.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7539-7548
-
-
Ito, M.1
Yoshioka, K.2
Akechi, M.3
Yamashita, S.4
Takamatsu, N.5
Sugiyama, K.6
Hibi, M.7
Nakabeppu, Y.8
Shiba, T.9
Yamamoto, K.I.10
-
38
-
-
33751274234
-
The JIP family of MAPK scaffold proteins
-
Whitmarsh A.J. The JIP family of MAPK scaffold proteins. Biochem. Soc. Trans. 2006, 34:828-832.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 828-832
-
-
Whitmarsh, A.J.1
-
39
-
-
0032508714
-
A mammalian scaffold complex that selectively mediates MAP kinase activation
-
Whitmarsh A.J., Cavanagh J., Tournier C., Yasuda J., Davis R.J. A mammalian scaffold complex that selectively mediates MAP kinase activation. Science 1998, 281:1671-1674.
-
(1998)
Science
, vol.281
, pp. 1671-1674
-
-
Whitmarsh, A.J.1
Cavanagh, J.2
Tournier, C.3
Yasuda, J.4
Davis, R.J.5
-
40
-
-
0035883958
-
Requirement of the JIP1 scaffold protein for stress-induced JNK activation
-
Whitmarsh A.J., Kuan C.Y., Kennedy N.J., Kelkar N., Haydar T.F., Mordes J.P., Appel M., Rossini A.A., Jones S.N., Flavell R.A., Rakic P., Davis R.J. Requirement of the JIP1 scaffold protein for stress-induced JNK activation. Genes Dev. 2001, 15:2421-2432.
-
(2001)
Genes Dev.
, vol.15
, pp. 2421-2432
-
-
Whitmarsh, A.J.1
Kuan, C.Y.2
Kennedy, N.J.3
Kelkar, N.4
Haydar, T.F.5
Mordes, J.P.6
Appel, M.7
Rossini, A.A.8
Jones, S.N.9
Flavell, R.A.10
Rakic, P.11
Davis, R.J.12
-
41
-
-
15044357454
-
Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways
-
Kelkar N., Standen C.L., Davis R.J. Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways. Mol. Cell. Biol. 2005, 25:2733-2743.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2733-2743
-
-
Kelkar, N.1
Standen, C.L.2
Davis, R.J.3
-
42
-
-
0037195113
-
JLP: a scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors
-
Lee C.M., Onesime D., Reddy C.D., Dhanasekaran N., Reddy E.P. JLP: a scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors. Proc. Natl Acad. Sci. USA 2002, 99:14189-14194.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 14189-14194
-
-
Lee, C.M.1
Onesime, D.2
Reddy, C.D.3
Dhanasekaran, N.4
Reddy, E.P.5
-
43
-
-
0032473569
-
A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways
-
Tapon N., Nagata K., Lamarche N., Hall A. A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways. EMBO J. 1998, 17:1395-1404.
-
(1998)
EMBO J.
, vol.17
, pp. 1395-1404
-
-
Tapon, N.1
Nagata, K.2
Lamarche, N.3
Hall, A.4
-
44
-
-
33744950092
-
Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs
-
Kukekov N.V., Xu Z., Greene L.A. Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs. J. Biol. Chem. 2006, 281:15517-15524.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15517-15524
-
-
Kukekov, N.V.1
Xu, Z.2
Greene, L.A.3
-
45
-
-
0034009390
-
Signal transduction: hanging on a scaffold
-
Burack W.R., Shaw A.S. Signal transduction: hanging on a scaffold. Curr. Opin. Cell Biol. 2000, 12:211-216.
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 211-216
-
-
Burack, W.R.1
Shaw, A.S.2
-
46
-
-
0034705227
-
Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties
-
Levchenko A., Bruck J., Sternberg P.W. Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties. Proc. Natl Acad. Sci. USA 2000, 97:5818-5823.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 5818-5823
-
-
Levchenko, A.1
Bruck, J.2
Sternberg, P.W.3
-
47
-
-
0038345695
-
Increased vulnerability to kainic acid-induced epileptic seizures in mice underexpressing the scaffold protein Islet-Brain 1/JIP-1
-
Magara F., Haefliger J.A., Thompson N., Riederer B., Welker E., Nicod P., Waeber G. Increased vulnerability to kainic acid-induced epileptic seizures in mice underexpressing the scaffold protein Islet-Brain 1/JIP-1. Eur. J. Neurosci. 2003, 17:2602-2610.
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 2602-2610
-
-
Magara, F.1
Haefliger, J.A.2
Thompson, N.3
Riederer, B.4
Welker, E.5
Nicod, P.6
Waeber, G.7
-
48
-
-
0038068111
-
The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells
-
Haefliger J.A., Tawadros T., Meylan L., Gurun S.L., Roehrich M.E., Martin D., Thorens B., Waeber G. The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells. J. Cell Sci. 2003, 116:1463-1469.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1463-1469
-
-
Haefliger, J.A.1
Tawadros, T.2
Meylan, L.3
Gurun, S.L.4
Roehrich, M.E.5
Martin, D.6
Thorens, B.7
Waeber, G.8
-
49
-
-
0034596017
-
IB1 reduces cytokine-induced apoptosis of insulin-secreting cells
-
Bonny C., Oberson A., Steinmann M., Schorderet D.F., Nicod P., Waeber G. IB1 reduces cytokine-induced apoptosis of insulin-secreting cells. J. Biol. Chem. 2000, 275:16466-16472.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16466-16472
-
-
Bonny, C.1
Oberson, A.2
Steinmann, M.3
Schorderet, D.F.4
Nicod, P.5
Waeber, G.6
-
50
-
-
0037081646
-
The scaffold protein IB1/JIP-1 controls the activation of JNK in rat stressed urothelium
-
Tawadros T., Formenton A., Dudler J., Thompson N., Nicod P., Leisinger H.J., Waeber G., Haefliger J.A. The scaffold protein IB1/JIP-1 controls the activation of JNK in rat stressed urothelium. J. Cell Sci. 2002, 115:385-393.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 385-393
-
-
Tawadros, T.1
Formenton, A.2
Dudler, J.3
Thompson, N.4
Nicod, P.5
Leisinger, H.J.6
Waeber, G.7
Haefliger, J.A.8
-
51
-
-
19344378845
-
IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation
-
Tawadros T., Martin D., Abderrahmani A., Leisinger H.J., Waeber G., Haefliger J.A. IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation. Cell. Signal. 2005, 17:929-939.
-
(2005)
Cell. Signal.
, vol.17
, pp. 929-939
-
-
Tawadros, T.1
Martin, D.2
Abderrahmani, A.3
Leisinger, H.J.4
Waeber, G.5
Haefliger, J.A.6
-
52
-
-
17044369165
-
JIP1 regulates neuronal apoptosis in response to stress
-
Dong Z., Zhou L., Del Villar K., Ghanevati M., Tashjian V., Miller C.A. JIP1 regulates neuronal apoptosis in response to stress. Brain Res. Mol. Brain Res. 2005, 134:282-293.
-
(2005)
Brain Res. Mol. Brain Res.
, vol.134
, pp. 282-293
-
-
Dong, Z.1
Zhou, L.2
Del Villar, K.3
Ghanevati, M.4
Tashjian, V.5
Miller, C.A.6
-
53
-
-
0030770614
-
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL
-
MacFarlane M., Ahmad M., Srinivasula S.M., Fernandes-Alnemri T., Cohen G.M., Alnemri E.S. Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL. J. Biol. Chem. 1997, 272:25417-25420.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25417-25420
-
-
MacFarlane, M.1
Ahmad, M.2
Srinivasula, S.M.3
Fernandes-Alnemri, T.4
Cohen, G.M.5
Alnemri, E.S.6
-
54
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
55
-
-
1842472483
-
Caspase activation inhibits proteasome function during apoptosis
-
Sun X.M., Butterworth M., MacFarlane M., Dubiel W., Ciechanover A., Cohen G.M. Caspase activation inhibits proteasome function during apoptosis. Mol. Cell 2004, 14:81-93.
-
(2004)
Mol. Cell
, vol.14
, pp. 81-93
-
-
Sun, X.M.1
Butterworth, M.2
MacFarlane, M.3
Dubiel, W.4
Ciechanover, A.5
Cohen, G.M.6
-
56
-
-
0035663673
-
Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway
-
Ikeda A., Hasegawa K., Masaki M., Moriguchi T., Nishida E., Kozutsumi Y., Oka S., Kawasaki T. Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway. J. Biochem. (Tokyo) 2001, 130:773-781.
-
(2001)
J. Biochem. (Tokyo)
, vol.130
, pp. 773-781
-
-
Ikeda, A.1
Hasegawa, K.2
Masaki, M.3
Moriguchi, T.4
Nishida, E.5
Kozutsumi, Y.6
Oka, S.7
Kawasaki, T.8
-
57
-
-
0035809914
-
Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules
-
Verhey K.J., Meyer D., Deehan R., Blenis J., Schnapp B.J., Rapoport T.A., Margolis B. Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. J. Cell Biol. 2001, 152:959-970.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 959-970
-
-
Verhey, K.J.1
Meyer, D.2
Deehan, R.3
Blenis, J.4
Schnapp, B.J.5
Rapoport, T.A.6
Margolis, B.7
-
58
-
-
0038701654
-
The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK
-
Willoughby E.A., Perkins G.R., Collins M.K., Whitmarsh A.J. The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK. J. Biol. Chem. 2003, 278:10731-10736.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10731-10736
-
-
Willoughby, E.A.1
Perkins, G.R.2
Collins, M.K.3
Whitmarsh, A.J.4
-
59
-
-
0032549670
-
Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals
-
Widmann C., Gibson S., Johnson G.L. Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals. J. Biol. Chem. 1998, 273:7141-7147.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7141-7147
-
-
Widmann, C.1
Gibson, S.2
Johnson, G.L.3
-
60
-
-
0035796481
-
Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components
-
Nihalani D., Meyer D., Pajni S., Holzman L.B. Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components. EMBO J. 2001, 20:3447-3458.
-
(2001)
EMBO J.
, vol.20
, pp. 3447-3458
-
-
Nihalani, D.1
Meyer, D.2
Pajni, S.3
Holzman, L.B.4
-
61
-
-
34548832749
-
Caspase-dependent cleavage disrupts the ERK cascade scaffolding function of KSR1
-
McKay M.M., Morrison D.K. Caspase-dependent cleavage disrupts the ERK cascade scaffolding function of KSR1. J. Biol. Chem. 2007, 282:26225-26234.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 26225-26234
-
-
McKay, M.M.1
Morrison, D.K.2
-
62
-
-
0031954631
-
MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis
-
Widmann C., Gerwins P., Johnson N.L., Jarpe M.B., Johnson G.L. MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis. Mol. Cell. Biol. 1998, 18:2416-2429.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2416-2429
-
-
Widmann, C.1
Gerwins, P.2
Johnson, N.L.3
Jarpe, M.B.4
Johnson, G.L.5
-
63
-
-
0032510794
-
Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1
-
Deak J.C., Cross J.V., Lewis M., Qian Y., Parrott L.A., Distelhorst C.W., Templeton D.J. Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1. Proc. Natl Acad. Sci. USA 1998, 95:5595-5600.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 5595-5600
-
-
Deak, J.C.1
Cross, J.V.2
Lewis, M.3
Qian, Y.4
Parrott, L.A.5
Distelhorst, C.W.6
Templeton, D.J.7
-
64
-
-
0034928845
-
Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP
-
Yang J.Y., Widmann C. Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP. Mol. Cell. Biol. 2001, 21:5346-5358.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5346-5358
-
-
Yang, J.Y.1
Widmann, C.2
-
65
-
-
13344259987
-
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells
-
Emoto Y., Manome Y., Meinhardt G., Kisaki H., Kharbanda S., Robertson M., Ghayur T., Wong W.W., Kamen R., Weichselbaum R., Kufe D. Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J. 1995, 14:6148-6156.
-
(1995)
EMBO J.
, vol.14
, pp. 6148-6156
-
-
Emoto, Y.1
Manome, Y.2
Meinhardt, G.3
Kisaki, H.4
Kharbanda, S.5
Robertson, M.6
Ghayur, T.7
Wong, W.W.8
Kamen, R.9
Weichselbaum, R.10
Kufe, D.11
-
66
-
-
0033966264
-
Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis
-
Irmler M., Steiner V., Ruegg C., Wajant H., Tschopp J. Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis. FEBS Lett. 2000, 468:129-133.
-
(2000)
FEBS Lett.
, vol.468
, pp. 129-133
-
-
Irmler, M.1
Steiner, V.2
Ruegg, C.3
Wajant, H.4
Tschopp, J.5
-
67
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin Y., Devin A., Rodriguez Y., Liu Z.G. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 1999, 13:2514-2526.
-
(1999)
Genes Dev.
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
68
-
-
0033955634
-
Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP
-
Martinon F., Holler N., Richard C., Tschopp J. Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP. FEBS Lett. 2000, 468:134-136.
-
(2000)
FEBS Lett.
, vol.468
, pp. 134-136
-
-
Martinon, F.1
Holler, N.2
Richard, C.3
Tschopp, J.4
-
69
-
-
0035860696
-
Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases
-
Harper N., Farrow S.N., Kaptein A., Cohen G.M., MacFarlane M. Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases. J. Biol. Chem. 2001, 276:34743-34752.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34743-34752
-
-
Harper, N.1
Farrow, S.N.2
Kaptein, A.3
Cohen, G.M.4
MacFarlane, M.5
-
70
-
-
0033975366
-
Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis
-
Rokudai S., Fujita N., Hashimoto Y., Tsuruo T. Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis. J. Cell. Physiol. 2000, 182:290-296.
-
(2000)
J. Cell. Physiol.
, vol.182
, pp. 290-296
-
-
Rokudai, S.1
Fujita, N.2
Hashimoto, Y.3
Tsuruo, T.4
-
71
-
-
0030867842
-
Cleavage of focal adhesion kinase by caspases during apoptosis
-
Wen L.P., Fahrni J.A., Troie S., Guan J.L., Orth K., Rosen G.D. Cleavage of focal adhesion kinase by caspases during apoptosis. J. Biol. Chem. 1997, 272:26056-26061.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26056-26061
-
-
Wen, L.P.1
Fahrni, J.A.2
Troie, S.3
Guan, J.L.4
Orth, K.5
Rosen, G.D.6
-
72
-
-
0032479435
-
Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide
-
Gervais F.G., Thornberry N.A., Ruffolo S.C., Nicholson D.W., Roy S. Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide. J. Biol. Chem. 1998, 273:17102-17108.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17102-17108
-
-
Gervais, F.G.1
Thornberry, N.A.2
Ruffolo, S.C.3
Nicholson, D.W.4
Roy, S.5
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