Flaxseed: A potential source of food, feed and fiber

Critical Reviews in Food Science and Nutrition

Volumn 51, Issue 3, 2011, Pages 210-222

  Singh, K K ^a   Mridula, D ^a   Rehal, Jagbir ^a   Barnwal, P ^a  

^a CENTRAL INSTITUTE OF POST HARVEST ENGINEERING AND TECHNOLOGY   (India)

Author keywords

Dehulling; Flaxseed; Health benefits; Nutritional composition; Oil expelling

Indexed keywords

DEHULLING; FLAXSEED; HEALTH BENEFITS; NUTRITIONAL COMPOSITIONS; OIL EXPELLING;

ANIMALS; FIBERS; FLAX; HEALTH; PHENOLS; UNSATURATED FATTY ACIDS;

OILSEEDS;

ANIMALS; FATTY ACIDS; FEEDS; FIBERS; LIGNANS; LINSEED OIL; OIL; PHENOLS;

ANIMALIA;

LIGNAN; LINOLENIC ACID;

ANIMAL; ANIMAL FOOD; CHEMISTRY; DIETARY FIBER; FLAX; HEALTH FOOD; HUMAN; PLANT SEED; REVIEW;

ALPHA-LINOLENIC ACID; ANIMAL FEED; ANIMALS; DIETARY FIBER; FLAX; HEALTH FOOD; HUMANS; LIGNANS; SEEDS;

EID: 79952427799     PISSN: 10408398     EISSN: 15497852     Source Type: Journal    
DOI: 10.1080/10408390903537241     Document Type: Article

References (160)

1. Aldercreutz, H. (2007). Lignans and human health. Critical Review Clinical Lab. Science. 44(5): 483-525.
2. Adlercreutz, H. (1988). Lignans and phytoestrogens. Possible preventative role in cancer. In: Frontiers of Gastrointestinal Research. pp. 165-176. Rozen, P., Ed., Karger, Basel.
3. Adlercreutz, H. (1990). Western diet and Western Diseases: Some hormonal and biochemical mechanisms and associations. Scand. J. Clin. Lab Inves. 50: 3-23.
4. Adlercreutz, H. (1995). Phytoestrogens: Epidemiology and a possible role in cancer protection. Environ. Health Perspect.103:103-112.
5. Adlercreutz, H. (1996a). Lignans and isoflavonoids: Epidemiology and a possible role in prevention of cancer. In: Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention. pp. 349-355. Kumpulainen, and Salonen, J.T., Eds., The Royal Society of Chemistry, London.
6. Adlercreutz, H. (1996b). Phytoestrogens from biochemistry to prevention of cancer and other diseases. In: The 8th International Congress on Menopause, Sydney, Australia, Maturitas, pp. 12-13.
7. Adlercreutz, H. (1990). Diet, breast cancer, and sex hormone metabolism. Annuals New York Academy of Sciences. 595: 281-290.
8. Adlercreutz, H., Fotsis, T., Bannwart, C., Hämäläinen, E., Bloigu, S., and Ollus, A. (1986). Urinary estrogen profile determination in young Finnish vegetarian and omnivorous women. Journal of Steroid Biochemistry and Molecular Biology. 24: 289-296.
9. Adlercreutz, H., Honjo, H., Higashi, A., Fotsis, T., Hämäläinen, E., Hasegawa, T., and Okada H. (1991). Urinary excretion of lignans and isoflavanoid phytoestrogens in Japanese men and women consuming a traditional Japansese diet. American Journal of Clinical Nutrition. 54: 1093-1100.
10. Adlercreutz, H., Widlt, vander J., Kinzel, J., Attalla, H., Wahala, K., Makela, T., Hase, T., and Fotsis, T. (1995). Lignan and isoflavonoid conjugates in human urine. J. Steroid Biochem. Mol. Biol. 52: 97-103.
11. Agricultural Marketing Service (2000). USDA, National Organic Program Final Rule, Federal Register 65: 80547-80684.
12. Akin, D. (2006). Developing standards to judge flax fiber quality. 28th International Cotton Conference, Bremen, Germany, pp. 177-187.
13. Anonymous (1962). The Wealth of India, Raw Materials, Vol. 6 (L.M). Council of Scientific and Industrial Research, New Delhi, India, p. 119.
14. Anonymous. (2000). Oil world statistics update. In: Oil World, 31, pp. 9-10.
15. Axelson, M., Sjovall, J., Gustafsson, B.E., and Setchell, K.D.R. (1982). Origin of lignans in mammals and identification of a precursor from plants. Nature. 298: 659-660.
16. Bell, J.M. and Keith, M.O. (1993). Nutritional evaluation of linseed meals from flax with yellow or brown hulls, using mice and pigs. Animal Feed Science and Technology 43:1-18.
17. Berglund, D.R. (2002). Flax: News uses and demands. In: Trends in New Crops and New Uses. pp. 358-360. Janick, J. and Whipkey, A., Eds., ASHS Press, Alexandria, VA.
18. Bergman Jungestrom, M., Thompson, L.U., and Dabrosin, C. (2007). Flaxseed and its lignans inhibit Estradiol-induced growth: Angiogenesis and secretion of vascular endothelial growth factor in Human Breast Cancer Xenografts in vivo. Clin. Cancer Research. 13(3): 1061-1067.
19. Best, D. (2004). Low-Carb revolution fuels innovation with flaxseed. http://www.functionalingredientsmag.com/fimag/articleDisplay.asp?strArticleId=514andstrSite=FFNSite.
20. Bhatty, R.S. (1995). Nutritional composition of whole flaxseed and flaxseed meal. In: Flaxseedin Human Nutrition, pp. 22-45. Cunnane, S.C. and Thompson, L.H., Eds., AOCS Press, Champaign, IL.
21. Bhatty, R.S. and Cherdkiagumchai, P (1990). Compositional analysis of laboratory-prepared and commercial samples of linseed meal and of hull isolated from flax. Journal of the American Oil Chemists Society 67: 79-84.
22. Bloedon, Le Anne. T., Balikai, Shilpa., Chittams, J., Cunnane, S.C., Berlin, J.A., Rader, D.J., and Szapary, P.O. (2008). Flaxseed and cardiovascular risk Factors: Results from a double blind, randomized, controlled clinical trail. Journal of the American College of Nutrition 27(1): 67-74.
23. Boghossian E. and Wegner, L.D. (2008). Use of flax fibers to reduce plastic shrinkage cracking in concrete. Cement and Concrete Composites 30(10): 929-937.
24. 2 extraction of flaxseed. Journal of the American Oil Chemists Society 79(3): 231-235.
25. Brown, F. (1953). The tocopherol content of farm-feeding stuffs. Journal Science Food Agricultural 4: 161.
26. Budavari, S. (1996). The Merck Index: An Encyclopaedia of Chemical, Drugs and Biologicals, 12th ed., Merck and Co, Inc., Whitehouse Station, NJ, p. 5511.
27. Burckhardt, A. (1989). Flax bread is a rising star of Wisconsin bakery. Minneapolis Star Tribune p. 45, 1/18/89.
28. Care, A.D. (1954). Goitrogenic properties of linseed. Nature. 173(4395): 172-173.
29. Carter, J.F. (1993).Potential of flaxseed and flaxseed oil in baked goodsandother products in human nutrition. Cereal Foods World 38(10): 753-759.
30. Charlet, K., Jernot, J.P., Gomina, M., Briad, J., Morvan, C. and Baley, C. (2006). Proceedings of ECCM 12, Biarritz.
31. Chen, Z.Y., Ratnayake, W.M.N., and Cunnane, S.C. (1994). Oxidative stability of flaxseed lipids during baking. Journal of the American Oil Chemists' Society 71 (6): 629-632.
32. Clark, W.F., Muir, A.D., Westcott, N.D., and Parbtani, A. (2000). A novel treatment for lupus nephritis: lignan precursor derived from flax. Lupus. 9: 429-436.
33. Clark, W.F., Kortas, C., Heidenhiem, A.P., Garland, J., Spanner, E., and Parbtani, A. (2001). Flaxseed in Lupus Nephritis: A Two-Year Nonplacebo-Controlled Crossover Study. Journal of the American College of Nutrition. 20(2):143-148.
34. Cui, W., Mazza, G., and Biliaderis, C.G. (1994). Chemical structure, molecular size distributions, and rheological properties of flaxseed gum. Journal of Agricultural and Food Chemistry 42: 1811-1895.
35. Cunnane, S.C., Ganguli, S., Menard, C., Liede, A.C., Hamadeh, M.J., Chen, Z.Y., Wolever, T.M.S., and Jenkins, D.J.A. (1993). High α-linolenic acid flaxseed (Linumusitatissimum): some nutritional properties in humans. British Journal of Nutrition. 49: 443-453.
36. Cunnane, S.C., Hamadeh, M.J., Liede, A.C., Thompson, L.U., Wolever, T.M., and Jenkins, D.J. (1995). Nutritional attributes of traditional flaxseed in healthy young adults. American Journal of Clinical Nutrition. 61: 62-68.
37. Daun, J.K., Barthet, V.J., Chornick, T.L., and Duguid, S. (2003). Structure, composition, and variety development of flaxseed. In: Flaxseed in Human Nutrition, pp.1-41. Cunnane, S.C. and Thompson, L.H., Eds., AOCS Press, Champaign, IL.
38. Dedio, W., and Dorrell, D.G. (1977). Factors affecting the pressure extraction of oil from flaxseed. Journal of the American Oil Chemists' Society 54(8): 313-315.
39. Demark-Wahnefried, W., Price, D.T., Polascik, T.J., Robertson, C.N., Anderson, E.E., Paulson, D.F., Walther, P.J., Gannon, M., and Vollmer, R.T. (2001). Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features. Urology 58: 47-52.
40. Dev, D.K., and Quensel, E. (1988). Preparation and functional properties of linseed protein products containing differing levels of mucilage. Journal of Food Sciences. 53: 1834-1837, 1857.
41. Dixit, S., Kendurkar, P.S., Vajpeyi, M., and Prasad, R.N. (2007). Variability in Elite Linseed (Linum usitatissimum L) Germplasm for oil content and fatty acid composition. Indian Journal of Agricultural Biochemistry. 20(1): 35-37.
42. Domier, K. and Kerr, N. (2000). The potential for agricultural fibers. Proceedings of the 58th Flax Inst., pp. 138-140.
43. Dorrell, D.G. (1970). Distribution of fatty acids in the seed of flax. Canadian Journal of Plant Science 50: 71-75.
44. Drouillard, J.S., Farran, T.B., Blasi, D.A., LaBrune, H.J., Montgomery, S.P., Sindt, J.J., Coetzer, C.M., Hunter, R.D., Spire, M.F., Elasasser, T.H., and Higgans, J.J. (2000). Modulation of immune response in feeder cattle with flaxseed. Proc. 58th Flax Institute, pp. 53-62.
45. Eastwood, L. (2008). The Nutritional Value of Flaxseed Meal for Swine, M.Sc. Thesis, University of Saskatchwan, Saskatoon, Saskatchwan.
46. Fedenuik, R.W. and Biliaderis, C.G. (1994). Composition and physicochemical properties of linseed (Linum usitatissimum L.) mucilage. Journal of Agricultural and Food Chemistry 42: 240-247.
47. Ford, J.D., Davin, L.B., and Lewis, N.G. (1999). Plant lignans and health: Cancer chemoprevention and biotechnological opportunities. Basic Life Science 66: 675-694.
48. Freeman, T.P. (1995). Structure of flaxseed. In: Flaxseed in Human Nutrition, pp.11-21. Cunnane, S.C. and Thompson, L.H., Eds., AOCS Press, Champaign, IL.
49. Garden-Robinson, J. (1994). Flaxseed gum: Extraction, composition, and selected applications. Proceedings of the 55th Flax Institute of the United States, Fargo, ND, pp. 154-165.
50. Gay, D. (1997). Materiaux Composites. Hermes, Paris.
51. Gonthier, C., Mustafa, A.F., Berthiaume, R., Petit, H.V., Martineau, R., and Ouellet, D.R. (2004). Effects of feeding micronized and extruded flaxseed on ruminal fermentation and nutrient utilization by dairy cows. Journal of Dairy Science 87: 1854-1863.
52. Gonzalez -Esquerra, R., and Lesson, S. (2000). Studies on the metabolizable energy content of ground full fat flaxseed fed in mash, pellet and crumbled diets assayed with birds of different ages. Poultry Science 79: 1603-1607.
53. Gopalan, C., Ramasastri, B.V., Subramanian, S.C. (2007). Nutritive Value of Indian Foods. National Institute of Nutrition, Hyderabad, India.
54. Gorder, D.D., Dolecek, T.A., Coleman, G.G., Tillotson, J.L., Brown, H.B., Lenz-Litzow, K., Bartsch, G.E., and Grandits, G. (1986). Dietary Intake in the Multiple Risk Factor Intervention Trial (MRFIT): Nutrient and food group changes over 6 years. Journal of American Dietetic Association 86: 744-751.
55. Gros, C., Lanoiselle, J.-L., and Vorobiev, E. (2003). Towards on alternative extraction process for linseed oil. Chemical Engineering Research and Design. 81(A9): 1059-1065.
56. Haggans, C.J., Hutchins, A.M., Olson, B.A., Thomas, W., Martini, M.C., and Slavin, J.L. (1999). Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Nutr. Cancer 33: 188-195.
57. Hall, A.A., III, Manthey, F.A., Lee, R.E., and Niehaus, M. (2005). Stability of α-Linolenic acid and secoisolariciresinol diglusoside in flaxseed fortified macaroni. Journal of Food Chemistry 70: C483-C489.
58. Hasler, C.M. (1998). Functional foods: Their role in disease prevention and health promotion. Food Technology 52(11): 63-70.
59. rd Flax Institute, pp. 26-40.
60. Holstun, J. and Zetocha, D. (1994). An Analysis of Flaxseed Utilization in the Health Food Industry. Institute for Business and Industry Development, North Dakota State University, Fargo, ND.
61. Hussain, S., Anjum, F.M., Butt, M.S., Khan, M.I., and Asghar, A. (2006). Physical and sensoric attributes of flaxseed flour supplemented cookies. Turkish Journal of Biology 30: 87-92.
62. Hutchins, A.M., Martini, M.C., Olson, B.A., Thomas, W., and Slavin, J.L. (2000). Flaxseed influences urinary lignan excretion in a dose-dependent manner in postmenopausal women. Cancer Epidemiology Biomarkers and Prevention 9: 1113-1118.
63. Ingram, D., Sanders, K., Kolybaba, M., and Lopez, D. (1997). Case-control study of phyto-oestrogens and breast cancer. Lancet 350: 990-994.
64. Javed, F. (1999). Flaxseed a boon to our life. Journal of Diabetic Association of India 39: 50-51.
65. Jenab, M. and Thompson, L.U. (1996). The influence of flaxseed and lignans on colon carcinogenesis and beta-glucuronidase activity. Carcinogenesis 17:1343-1348.
66. Jenkins, D.J., Kendall, C.W., Vidgen, E., Agarwal, S., Rao, A.V., Rosenberg, R.S., Diamandis, E.P., Novokmet, R., Mehling, C.C., Perera, T., Griffin, L.C., and Cunnane, S.C. (1999). Health aspects of partially defatted flaxseed, including effects on serum lipids, oxidative measures, and ex vivo androgen and progestin activity: a controlled crossover trial. American Journal of Clinical Nutrition. 69:395-402.
67. Johnsson, P., Kamal-Eldin, A., Lundgren, L.N., and Aaman, P. (2000). HPLC method for analysis of secoisolariciresinol diglucoside in flaxseeds. Journal of Agricultural and Food Chemistry 48(11): 5216-5219.
68. Kangas, N., Niehaus, M., and Hall, C.A., III. (2006). Utlization of flaxseed gum in dairy foods. In: Proceedings of the 61st Flax Institute of the U.S., Carter, J.F., Ed., pp. 205-212, North Dakota State University, Fargo, ND.
69. Kashtan, H., Stern, H.S., Jenkins, D.J., Jenkins, A.L., Thompson, L.U., Hay, K., Marcon, N., Minkin, S., and Bruce, W.R. (1992). Colonic fermentation and markers of colorectal-cancer risk. American Journal of Clinical Nutrition. 55: 723-728.
70. Kettler, D.B. Flax Seed Oil Research. http://www.gaiaresearch.co.za/flaxsee-doil.html. (Accessed June, 2006).
71. Kitts, D.D., Y.V. Yuan, A.N. Wijewickreme, and L.U. Thompson. (1999). Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. Molecular and Cellular Biochemistry 202(1-2): 91-100.
72. Kozlowska, J., Munoz, G.A., and Kolodziejczyk, P.P. (2008). Food and feed applications for flaxseed components. In: 2008 International Conference on Flax and other Bast Plants, pp. 299-307. Saskatoon, Canada.
73. Kuijsten, A., Arts, I.C., van't Veer P., and Hollman, P.C. (2005). The relative bioavailibility of enterolignansin humans is enhanced by milling and crushing of flaxseed. J. Nutr. 135(12): 2812-2816.
74. Kurzer, M.S., Slavin, J.L., and Adlercreutz, H. (1995). Flaxseed, lignans and sex hormones. In: Flaxseed in Human Nutrition, pp.136-144. Cunnane, S.C., and Thompson, L.U., Eds., AOCS Press, Champaign, IL.
75. Lay, C.L. and Dybing, D.D. (1989). Linseed. In: oil crops of the world, pp. 416-430. Robbelen, G., Downey, R.K., and Ashri, A., Eds., McGraw Hill, New York.
76. Lee, R.E., Manthey, F.A., and Hall, C.A., III (2004). Content and stability of hexane extractable lipid at various steps of producing macaroni containing ground flaxseed. Journal of Food Processing and Perseveration. 28: 133-144.
77. Leskanich, C.O. and Noble, R.C. (1997). Manipulation of the n-3 polysaturated fatty acid composition of avian eggs and meat. World's Poult. Sci. 15:183-189.
78. Li, D., Sinclair, A., Wilson, A., Nakkote, S., Kelly, F., Abedin, L., Mann, N., and Turner, A. (1999). Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men. The American Journal of Clinical Nutrition 69(5): 872-882.
79. Madhusudhan, B., Wiesenborn, D., Schwarz, J., Tostenson, K. and Gillespie, J. (2000). A dry mechanical method for concentrating the lignan secoisolariciresinol diglucoside in flaxseed. Lebensmittel-Wissenschaft und Technologie 33: 268-275.
80. Malcolmson, L.J., Przybylski, R., and J.K. Daun. (2000). Storage stability of milled flaxseed. Journal of the American Oil Chemists' Society 77(3): 235-238.
81. Mente, O. (2008). Effect of the use of ground flaxseed on quality and chemical properties of bread. Food Science and Technology International 14(4):299-306.
82. Manthey, F.A., Sinha, S., Wolf-Hall, C.E., and Hall, C.A. III (2008). Effects of flaxseed flour and packaging on shelf life of refrigerated pasta. Journal of Food Processing and Preservation 32: 75-87.
83. Mantzioris, E., Cleland, L.G., Gibson, R.A., Neumann, M.A., Demasi, M., and James, M.J. (2000). Biochemical effects of a diet containing foods enriched with n-3 fatty acids. The American Journal of Clinical Nutrition 72(1): 42-48.
84. Marconi, E. and Carcea, M. (2001). Pasta from non-traditional raw materials. Cereal Foods World 46: 522-530.
85. Mazur, W., Fotsis, T., Wähälä, K., Ojala, S., Salakka, A., and Adlercreutz, H. (1996). Isotope dilution gas chromatographic-mass spectrometric method for the determination of isoflavonoids, coumestrol, and lignans in food samples. Analytical Biochemistry 233: 169-180.
86. Mazza, G. (2008). Production, Processing and Uses of Canadian Flax. First CGNA International Workshop, Temuco, Chile, August 3-6.
87. Mazza, G. and C.G. Biliaderis. (1989). Functional properties of flax seed mucilage. Journal of Food Science 54(5): 1302-1305.
88. Mazza, G., and Oomah, B.D. (1995). Flaxseed, Dietary Fiber and Cyanogens. In: Flaxseed in Human Nutrition, pp. 56-81. Cunnane, S.C. and Thompson, L.U., Eds., AOCS Press, Champaign, IL.
89. Mazza, G., Biliaderis, C.G., and Oomah, B.D. (1992). Extraction and functional properties of flaxseed gum. Proceedings of the 54th Flax Institute of the United States, Fargo, ND, pp. 84-92.
90. Morris, D.H. (2001). Essential nutrients and other functional compounds in flaxseed. Nutrition Today. 36: 159-162.
91. Morris, D.H. (2003). Flax - A Health and Nutrition Primer. Winnipeg, Manitoba: Flax Council of Canada. http://www.flaxcouncil.ca.
92. Morris, D.H. Flax reduces inflammation leading to athesoslerosis: New flax facts. Flax Council of Canada. http://www.flaxcouncil.ca/english/pdf/FFAtherosclerosR3.pdf
93. Mousavi, Y. and Adlercreutz, H. (1992). Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. Journal of Steroid Biochemistry and Molecular Biology 41: 615-619.
94. Muir, A.D., Westcott, N.D. and Prasad K. (1999). Extraction, purification and animal model testing of an anti-artherosclerotic lignan secoisolariciresinol digluoside from flaxseed (Linum usitatissmum). Acta Hort.(ISHS) 501:245-248.
95. Nesbitt, P.D. and Thompson, L.U. (1997). Lignans in homemade and commercial products containing flaxseed. Nutr. Cancer. 29: 222-227.
96. Ogborn, M.R., Nitschmann, E., and Weiler, H. (1999). Flaxseed ameliorates interstitial nephritis in rat polycystic kidney disease. Kidney Int. 55: 417-423.
97. Ohr, M.L. (2002). A growing arnesal against cancer. Food Technology. 56: 67-71.
98. Oomah, B.D. (2001). Flaxseed as a functional food source. Journal of the Science of Food and Agricultural. 81(9): 889-894.
99. Oomah, B.D. and Mazza, G. (1998a). Flaxseed products for disease prevention. In: Functional Foods: Biochemical and Processing Aspects, pp. 91-138. Mazza, G., Ed., Technomic Publishing Co, Inc., Lancaster, PA.
100. Oomah, B.D. and Mazza, G. (1998b). Fractionation of flaxseed with a batch dehuller. Industrial Crops and Products. 9 (1):19-27.
101. Oomah, B.D. and Sitter, L. (2009). Characteristics of flaxseed hull oil. Food Chemistry 114 (2):623-628.
102. Oomah, B.D., Reichert, R.D., and Youngs, C.G. (1981). A novel, multisample, Tangertial Abrasive dehulling device (TADD). Cereal Chemistry 58: 392-395.
103. Oomah, D.B. and Mazza, G. (1997). Effect of dehulling on chemical composition and physical properties of flaxseed. Lebensmittel-Wissenschaft and Und Technologies 30(2): 135-140.
104. Oomah, D.B., Mazza, G., and Kenaschuk, E.O. (1996). Dehulling characteristics of flaxseed. Lebensmittel-Wissenschaft and Und Technologies 29(3): 245-250.
105. Petit, Helene V. (2002). Digestion, Milk production, Milk composition and blood composition of dairy cows fed whole flaxseed. Journal of Dairy Science 85(6): 1482-1490.
106. Phipps, W.R., Martini, M.C., Lampe, J.W., Slavin, J.L., and Kurzer, M.S. (1993). Effect of flax seed ingestion on the menstrual cycle. Journal of Clinical Endocrinology and Metabolism. 77: 1215-1219.
107. Pohjanheimo, T.A., Hakala, M.A., Tahvonen, R.L., Salminen, S.J., and Kallio, H.P. (2006). Flaxseed in breed making: Effects on sensory quality, aging, and composition of bakery products. Journal of Food Science 71: 5343-5348.
108. Power, K.A. and Thompson, L.U. (2007). Can the combination of flaxseed and its lignans with soy and its isoflavones reduce the growth stimulatory effect of soy and its isoflavones on established breast cancer. Mol Nutr Food Res. 51(7):845-856.
109. Prasad, K. (1997). Hydroxyl radical-scavenging property of secoisolariciresinol diglycoside (SDG) isolated from flax-seed. Molecular and Cellular Biochemistry. 168(1-2): 117-123.
110. Prasad, K. (2000a). Flaxseed: A source of hypocholesterolemic and anti atherogenic agents. Drug News Perspect 13(2): 99.
111. Prasad, K. (2000b). Antioxidant activity of secoisolariciresinol diglucoside-derived metabolites, secoisolariciresinol, enterodiol, and enterolactone. Internatl. J. Angiol. 9:220-225.
112. Prasad, K., Mantha, S.V., Muir, A.D., and Westcott, N.D. (1998). Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alphalinolenic acid. Atherosclerosis. 136: 367-375.
113. Ramcharitar, A., Badrie, N., Mattfeldt-Beman, M., Matsuo, H., and Ridley, C. (2005). Consumer acceptability of muffins with flaxseed (Linum usitatissimum) Journal of Food Science 70(7):S504-S507.
114. Reichert, R.D., Tyler York, A.E., Schwab, D.J., Tatarynovich, J.E., and Mwasaru, M.A. (1986). Description of a production model of the tangential abrasive dehulling device and its application to breeders' samples. Cereal Chemistry.63: 201-207.
115. Rickard, S.E., Yuan, Y.V., and Thompson, L.U. (2000). Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. Cancer Letters 161: 47-55.
116. Ridges, L., Sunderland, R., Moerman, K., Meyer, B., Astheimer, L., Howe, P. (2001). Cholesterol lowering benefits of soy and linseed enriched foods. Asia Pacific Journal of Clinical Nutrition 10(3): 204-211.
117. Sahu, A., Vajpeyi, M., and Mohan, M. (2006). A simple technique for the removal of linamarin from linseed (Linum usitatissimum.L) meal. International Conferenceon Post-Harvest Technology and Value Additionin Cereals, Pulses and Oilseeds, Nov 27-30, 2006, Kanpur, India.
118. Salunke, D.K. and Desai, B.B. (1986). Linseed, niger and cottonseed. In: Post harvest Biotechnology of Oil seeds. pp. 171-186. CRC Press, Boca Raton, FL.
119. Sathyamoorthy, N., Wang, T.T., and Phang, J.M. (1994). Stimulation of pS2 expression by diet-derived compounds. Cancer Research 54: 957-961.
120. Scholljegerdes, E. and Kronberg, S. (2007). Effects of supplemental ground flaxseed on the growth performance of steers grazing summer native pasture in the northern great plains. Proceedings, Western Section, American Society of Animal Science 58: 248-251.
121. Serraino, M. and Thompson, L.U. (1992). The effect of flaxseed supplementation on the initiation and promotional stages of mammary tumorigenesis. Nutrition and Cancer 17: 153-159.
122. Setchell, K.D., Lawson, A.M., Mitchell, F.L., Adlercreutz, H., Kirk, D.N., and Axelson, M. (1980). Lignans in man and in animal species. Nature 287: 740-742.
123. Setchell, K.D., Lawson, A.M., Borriello, S.P., Harkness, R., Gordon, H., Morgan, D.M., Kirk, D.N., Adlercreutz, H., Anderson, L.C., and Axelson, M. (1981). Lignan formation in man-microbial involvement and possible roles in relation to cancer. Lancet 2: 4-7.
124. Shahidi, F. and Naczk, M. (2004). Biosynthesis, classification, and nomenclature of phenolics in food and nutraceuticals. In: Phenolics in Food and Nutraceuticals, pp. 1-16. CRC Press, Boca Raton, FL.
125. Shen, Y., Feng, D., and Chavez, E.R. (2004). Effect of flaxseed processing on its true metabolizable energy values for adult chicken. Journal of the Science of Food and Agriculture 84(6): 551-555.
126. Shen, Y., Feng, D., Oresanya, T.F. and Chavez, E.R. (2005). Fatty acid and nitrogen utilization of processed flaxseed by adult chickens. Journal of the Science of Food and Agriculture 85(7): 1137-1142.
127. Shukla, V.K. S. (2003). A designer oil for better health. International News on Fats, Oils and Related Materials. 14(6): 340-341.
128. Simopoulos, A.P. (1999). Essential fatty acids in health and chronic disease. The American Journal of Clinical Nutrition 70(3): 560-569.
129. Singh, J. and Bargale, P.C. (2000). Development of a small capacity double stage compression screw press for oil expression. Journal of Food Engineering 43: 75-82.
130. Singh, K.K., Wiesenborn, D., Kangas, N., and Tostenson, K. (2002a). Characterization of cooking parameters for improved screw pressing of crambe seed. Transactions of the ASAE 45(4): 1029-1035.
131. Singh, K.K., Wiesenborn, D., Tostenson, K., and Kangas, N. (2002b). Influence of moisture content on pressing characteristics of crambe. Journal of American Oil Chemists' Society 79 (2): 165-170.
132. Smith, A.K., Johnsen, V.L., and Berkel, A.C. (1946). Linseed proteins alkali dispersion and acid precipitation. Industrial and Engineering Chemistry 38: 353-356.
133. Soita, H.W., Meier, J.A., Fehr, M., Christensen, D.A., Mckinon, J.J., Yu, P., Mustafa, A.F. (2003). Effect sofflax seed supplementation on milk production, milk fatty acid composition and nutrient utilization by lactating dairy cows. Archives of Animal Nutrition 57(2): 107-116.
134. Sosulski, F.W. and Cadden, A.M. (1982). Composition and physiological properties of several sources of dietary fiber. Journal of Food Science 47:1472-1477.
135. Spence, J.D., Thornton, T., Muir, A.D., and Westcott, N.D. (2003). The effect of flax seed cultivars with differing content of alpha-linolenic acid and lignans on responses to mental stress. J. Am. Coll. Nutr. 22: 494-501.
136. rd Flax Institute, pp. 20-24.
137. Susheelamma, N.S. (1987). Isolation and properties of linseed mucilage. Lebensmittel-Wissenschaft Und-Technologie 24: 103-106.
138. Tarpila, S., Tarpila, A., Grhn, P., Silvennoinen, T., and Lindberg, L. (2004). Efficacy of ground flaxseed on constipation in patients with irritable bowel syndrome. Current Topics in Nutraceutical Research 2(2):119-125.
139. Thiessen, D. (2004). Optimization of feed peas, canola and flaxseed for aqua feeds: The Canadian prairie perspective. In: Advances en Nutricion Acuicola VII. Memorial del VII Simposium Internacional de Nutricion. Cruz Suarez, L.E., Ricque, M., D., Lopez, N., Villarreal, M.G., Scholz, D., Gonzalez, U., and Acuicola, M. 16-19 November, 2004 Hermosillo, Sonora, Mexico.
140. Thiessen, D.L., Campbell, G.L., and Addizi, P.D. (2003). Digestibility and growth performance of juvenile rainbow trout (Oncohychus mykiss) fed with pea and canola products. Aqua. Nutr. 9: 67-75.
141. Thiessen, D.L., Maenz, D.D., Newkrik, R.W., Classen, H.L., and Drew M.D. (2004). Replacement of fish meal by canola protein concentrate in diets fed to rainbow trout (Oncorhychus mykiss). Aqua. Nutr. 10(6):379-388.
142. Thompson, L.U., T. Li, J. Chen, and Goss, P.E. (2000). Biological effects of dietary flaxseed in patients with breast cancer. Breast Cancer Research and Treatment 64(1): 50.
143. Thompson, L.U. (1999). Role of lignans in carcinogenesis, in phytochemicals in human health protection, nutrition, and plant defense. In: Recent Advance in Phytochemistry, p. 33. Romeo, J.T, Ed., Kluwer, New York.
144. Thompson, L.U., Seidl, M.M., Rickard, S.E., Orcheson, L.J., and Fong, H.H. (1996). Antitumorigenic effect of a mammalian lignan precursor from flaxseed. Nutrition and Cancer. 26:159-165.
145. Tou, J.C. and Thompson, L.U. (1999). Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures. Carcinogenesis 20: 1831-1835.
146. Turner, J. (1987). Linseed Law. BASF Ltd., UK.
147. Tzen, J.T. C., Y.Z. Cao, P. Laurent, C. Ratnayake, and Huang, A.H.C. (1993). Lipids, proteins, and structure of seed oil bodies from diverse species. Plant Physiology 101: 267-276.
148. Vaisey-Genser, M. (2003). Introduction: History of the cultivation and uses of flaxseed. In: Flax, the Genus Linum. pp. 1-21. Muir, A.D. and Westcott, N.D., Eds., Taylor and Francis, London.
149. Van De Wayberg, I. and Verpoest, I. (2002). Knitted flax fiber polyester composites. Proceedings of the International Symposium on Material Science, Sustainable Natural and Polymeric Composites-Science and Technology, Roskilde, 2-5 September, 2002, pp. 341-348.
150. Vassel, B. and Nesbitt, L.L. (1945). The nitrogenous constituents of flaxseed. II. The isolation of a purified protein fraction. Journal of Biological Chemistry 159: 571-584.
151. Wang, H.H., Drummond, J.G., Reath, S.M., Hunt, K. and Watson, P.A. (2001). An improved fibril angle measurement method for wood fibers. Wood Science and Technology 34: 493-503.
152. Wannerberger, K., Nylander, T., and Nyman, M. (1991). Rheological and chemical properties of mucilage in different varieties from linseed (Linum usitatissimum). Acta Agriculturea Scandinavica 41: 311-319.
153. Westcott, N.D. and Muir, A.D. (2003). Chemical studies on the constituents of Linuum spp. In: Flax, The Genus Linum, pp. 55-73. Muir, A.D. and Westcott, N.D., Eds., Taylor and Francis, London.
154. Westcott, N.D. and Muir, A.D. (1996). Variation in the concentration of the flax seed lignan concentration with variety, location and year. In: Proceedings of the 56th Flax Institute of the United States Conference, Flax Institute of the United States, Fargo, ND, pp. 77-80.
155. Westcott, N.D. and Muir, A.D. (1997). Medicinal Lignan from Flaxseed. In: Prairie Medicinal and Aromatic Plants Conference, pp. 71-76. Brandon, Manitoba.
156. Wiesenborn, D., Tostenson, K., Kangas, N., Zheng, Y., Hall, Clifford., Niehaus, M., Jarvis, P., Schwaz, J., and Twombly, W. (2005). Processing flaxseed for food and feed uses. Food Science Biotechnology 14(1): 1-6.
157. Xu, Y., Hall, C., III, Wolf-Hall, C. and Manthey, F. (2006). Antifungal activity of flaxseed flours. In: Proocedings of the 61st Flax Institute of the U.S. pp. 177-185. Carter, J.F., Ed., North Dakota State University, Fargo, ND.
158. Zhang, Z.S., Wang Li, J., Li, D., Jiao, S.S., Chen, D.X., and Mao, Z.H. (2008). Ultrasound -assisted extraction of oil from flaxseed. Separation and Purification Technology.62(1): 192-198.
159. Zheng, Y.L., Wiesenborn, D.P., Tostenson, K., and Kangas, N. (2005). Energy analysis in the screw pressing of whole and dehulled flaxseed. Journal of Food Engineering 66: 193-202.
160. Zheng, Y.L., Wiesenborn, D., Tostenson, K., and Kangas, N. (2003). Screw pressing of whole and dehulled flaxseed for organic oil. Journal of American Oil Chemists Society. 80(10): 1039-1045.