Interaction of carbon monoxide with transition metals: Evolutionary insights into drug target discovery

Current Drug Targets

Volumn 11, Issue 12, 2010, Pages 1595-1604

  Foresti, Roberta ^a   Motterlini, Roberto ^a  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

Carbon monoxide; Carbon monoxide releasing molecules; Hemoglobin; Mitochondria; Transition metals

Indexed keywords

CARBON MONOXIDE; CARBON MONOXIDE RELEASING MOLECULE; CARBOXYHEMOGLOBIN; CYTOCHROME C OXIDASE; DRUG VEHICLE; HEME; HEMOGLOBIN; TRANSITION ELEMENT; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; HEME OXYGENASE; IRON; ORGANOMETALLIC COMPOUND;

ANTIINFLAMMATORY ACTIVITY; COMPLEX FORMATION; DRUG DELIVERY SYSTEM; DRUG TARGETING; HUMAN; IRON BINDING CAPACITY; MITOCHONDRIAL RESPIRATION; MOLECULAR INTERACTION; NONHUMAN; REVIEW; SYNTHESIS; VASODILATATION; ANIMAL; BIOSYNTHESIS; BLOOD; CARBON MONOXIDE INTOXICATION; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; BIOLOGICAL MARKERS; CARBON MONOXIDE; CARBON MONOXIDE POISONING; CARBOXYHEMOGLOBIN; DRUG DESIGN; ELECTRON TRANSPORT COMPLEX IV; HEME OXYGENASE (DECYCLIZING); HUMANS; IRON; ORGANOMETALLIC COMPOUNDS; SIGNAL TRANSDUCTION; TRANSITION ELEMENTS;

EID: 79952278599     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/1389450111009011595     Document Type: Review

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