Carbon monoxide prevents multiple organ injury in a model of hemorrhagic shock and resuscitation

Shock

Volumn 23, Issue 6, 2005, Pages 527-532

  Zuckerbraun, Brian S ^a   McCloskey, Carol A ^a   Gallo, David ^a   Liu, Fang ^a   Ifedigbo, Emeka ^a   Otterbein, Leo E ^a,b,c   Billiar, Timothy R ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Carbon monoxide; Circulatory collapse; Heme oxygenase; Hemorrhagic shock; Inflammation; Nitric oxide

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBON MONOXIDE; HEME OXYGENASE; INTERLEUKIN 10; NITRIC OXIDE; RINGER LACTATE SOLUTION;

ANESTHESIA INDUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLEEDING; CANNULATION; CELL HYPOXIA; CELL PROTECTION; CELL VIABILITY; ENZYME ACTIVITY; HEMORRHAGIC SHOCK; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIVER CELL; MEAN ARTERIAL PRESSURE; MOUSE; MOUSE STRAIN; MULTIPLE ORGAN FAILURE; NONHUMAN; PROTEIN BLOOD LEVEL; RESUSCITATION;

ADENOSINE TRIPHOSPHATE; AIR; ANIMALS; ANOXIA; CARBON MONOXIDE; CELL DEATH; CELL SURVIVAL; CYTOKINES; DISEASE MODELS, ANIMAL; HEMORRHAGE; HEPATOCYTES; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-6; INTESTINES; LIVER; LUNG; MICE; MICE, INBRED C57BL; OXYGEN CONSUMPTION; PEROXIDASE; PRESSURE; RESUSCITATION; SHOCK, HEMORRHAGIC; TIME FACTORS;

EID: 18744380991     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000163206.22032.a1     Document Type: Article

References (26)

1. Injury facts. In. Itasca, IL: National Safety Council, 2000.
2. Peitzman AB, Billiar TR, Harbrecht BG, Kelly E, Udekwu AO, Simmons RL: Hemorrhagic shock. Curr Probl Surg 32:925-1002, 1995.
3. Bond RF, Manley ES Jr, Green HD: Cutaneous and skeletal muscle vascular responses to hemorrhage and irreversible shock. Am J Physiol 212:488-497, 1967.
4. Rensing H, Bauer I, Datene V, Patau C, Pannen BH, Bauer M: Differential expression pattern of heme oxygenase-1/heat shock protein 32 and nitric oxide synthase-II and their impact on liver injury in a rat model of hemorrhage and resuscitation. Crit Care Med 27:2766-2775, 1999.
5. Otterbein LE, Choi AM: Heme oxygenase: colors of defense against cellular stress. Am J Physiol Lung Cell Mol Physiol 279:L1029-LI037, 2000.
6. Otterbein LE, Soares MP, Yamashita K, Bach FH: Heme oxygenase-1: unleashing the protective properties of heme. Trends Immunol 24:449-455, 2003.
7. Otterbein LE, Zuckerbraun BS, Haga M, Liu F, Song R, Usheva A, Stachulak C, Bodyak N, Smith RN, Csizmadia E, Tyagi S, Akamatsu Y, Flavell RJ, Billiar TR, Tzeng E, Bach FH, Choi AM, Soares MP: Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nat Med 9:183-190, 2003.
8. Zuckerbraun BS, Billiar TR, Otterbein SL, Kim PK, Liu F, Choi AM, Bach FH, Otterbein LE: Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1. J Exp Med 198:1707-1716, 2003.
9. Otterbein LE, Bach FH, Alam J, Soares M, Tao Lu H, Wysk M, Davis RJ, Flavell RA, Choi AM: Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 6:422-428, 2000.
10. Brouard S, Otterbein LE, Anrather J, Tobiasch E, Bach FH, Choi AM, Soares MP: Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J Exp Med 192:1015-1026, 2000.
11. Sato K, Balla J, Otterbein L, Smith RN, Brouard S, Lin Y, Csizmadia E, Sevigny J, Robson SC, Vercellotti G, Choi AM, Bach FH, Soares MP: Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants. J Immunol 166:4185-4194, 2001.
12. Fujita T, Toda K, Karimova A, Yan SF, Naka Y, Yet SF, Pinsky DJ: Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis. Nat Med 7:598-604, 2001.
13. McCloskey CA, Zuckerbraun BS, Gallo DJ, Vodovotz Y, Billiar TR: A role for angiotensin II in the activation of extracellular signal-regulated kinases in the liver during hemorrhagic shock. Shock 20:316-319, 2003.
14. Anderson BO, Brown JM, Bensard DD, Grosso MA, Banerjee A, Patt A, Whitman GJ, Harken AH: Reversible lung neutrophil accumulation can cause lung injury by elastase-mediated mechanisms. Surgery 108:262-267, 1990; discussion 267-268.
15. Koch CJ, Lord EM, Shapiro IM, Clyman RI, Evans SM: Imaging hypoxia and blood flow in normal tissues. Adv Exp Med Biol 428:585-593, 1997.
16. Imai T, Morita T, Shindo T, Nagai R, Yazaki Y, Kurihara H, Suematsu M, Katayama S: Vascular smooth muscle cell-directed overexpression of heme oxygenase-1 elevates blood pressure through attenuation of nitric oxide-induced vasodilation in mice. Circ Res 89:55-62, 2001.
17. Kajimura M, Goda N, Suematsu M: Organ design for generation and reception of CO: lessons from the liver. Antioxid Redox Signal 4:633-637, 2002.
18. Suematsu M, Suganuma K, Kashiwagi S: Mechanistic probing of gaseous signal transduction in microcirculation. Antioxid Redox Signal 5:485-492, 2003.
19. Meng ZH, Dyer K, Billiar TR, Tweardy DJ: Distinct effects of systemic infusion of G-CSF versus IL-6 on lung and liver inflammation and injury in hemorrhagic shock. Shock 14:41-48, 2000.
20. Hierholzer C, Kalff JC, Chakraborty A, Watkins SC, Billiar TR, Bauer AJ, Tweardy DJ: Impaired gut contractility following hemorrhagic shock is accompanied by IL-6 and G-CSF production and neutrophil infiltration. Dig Dis Sci 46:230-241, 2001.
21. Kahlke V, Dohm C, Mees T, Brotzmann K, Schreibet S, Schroder J: Early interleukin 10 treatment improves survival and enhances immune function only in males after hemorrhage and subsequent sepsis. Shock 18:24-28, 2002.
22. Nakao A, Moore BA, Murase N, Liu F, Zuckerbraun BS, Bach FH, Choi AM, Nalesnik MA, Otterbein LE, Bauer AJ: Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility. Gut 52:1278-1285, 2003.
23. Suematsu M, Kashiwagi S, Sano T, Goda N, Shinoda Y, Ishimura Y: Carbon monoxide as an endogenous modulator of hepatic vascular perfusion. Biochem Biophys Res Commun 205:1333-1337, 1994.
24. Suematsu M, Goda N, Sano T, Kashiwagi S, Egawa T, Shinoda Y, Ishimura Y: Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver. J Clin Invest 96:2431-2437, 1995.
25. Suematsu M, Wakabayashi Y, Ishimura Y: Gaseous monoxides: a new class of microvascular regulator in the liver. Cardiovasc Res 32:679-686, 1996.
26. Lavitrano M, Smolenski RT, Musumeci A, Maccherini M, Slominska E, Di Florio E, Bracco A, Mancini A, Stassi G, Patti M, Giovannoni R, Froio A, Simeone F, Forni M, Bacci ML, D'Alise G, Cozzi E, Otterbein LE, Yacoub MH, Bach FH, Calise F: Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs. FASEB J 18:1093-1095, 2004.