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Volumn 306, Issue 5704, 2004, Pages 2093-2097

Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CARBON MONOXIDE; OXYGEN; SENSORS; TISSUE;

EID: 10844248490     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1105010     Document Type: Article
Times cited : (411)

References (24)
  • 15
    • 10844241587 scopus 로고    scopus 로고
    • note
    • Western blot analysis of wild-type and BKαβ cells.
  • 17
    • 10844248527 scopus 로고    scopus 로고
    • note
    • Application of 30 μM of CO donor did not activate channels in wild-type cells.
  • 18
    • 0141963861 scopus 로고    scopus 로고
    • X. D. Tang et al., Nature 425, 531 (2003).
    • (2003) Nature , vol.425 , pp. 531
    • Tang, X.D.1
  • 19
    • 10844254954 scopus 로고    scopus 로고
    • note
    • Heme (1 nM) did not activate BKαβ channels; n = 8 patches; P > 0.25.
  • 20
    • 10844245637 scopus 로고    scopus 로고
    • note
    • CO donor (30 μM) increased NPo by a factor of 25 in membrane patches from carotid body glomus cells; n = 7 patches.
  • 24
    • 10844288051 scopus 로고    scopus 로고
    • note
    • We thank J. Keen and A. Ashcroft for technical and scientific input into the 2D and spectroscopic analyses; S. Bourke, S. Calaghan, and T. Batten for microscopy; J. Kennedy for advice on inorganic syntheses; and M. Ashford for providing the BKαβ HEK293 cells. S.E.J.W. held a Commonwealth Scholarship. Funded by British Heart Foundation and Wellcome Trust.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.