Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-x-receptor

Journal of Medicinal Chemistry

Volumn 54, Issue 5, 2011, Pages 1314-1320

  Sepe, Valentina ^a   Bifulco, Giuseppe ^b   Renga, Barbara ^c   D'Amore, Claudio ^c   Fiorucci, Stefano ^c   Zampella, Angela ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FARNESOID X RECEPTOR; STEROL DERIVATIVE;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; GENE EXPRESSION; LIVER CELL; MOLECULAR DOCKING; PROMOTER REGION; PROTEIN SECRETION;

ANIMALS; BINDING SITES; ECHINODERMATA; HEP G2 CELLS; HUMANS; HYDROXYSTEROIDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STEROLS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFURIC ACID ESTERS; TRANSCRIPTION FACTORS;

EID: 79952274483     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm101336m     Document Type: Article

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