Structural basis for bile acid binding and activation of the nuclear receptor FXR

Molecular Cell

Volumn 11, Issue 4, 2003, Pages 1093-1100

  Mi, Li Zhi ^a   Devarakonda, Srikripa ^a   Harp, Joel M ^a   Han, Qing ^a   Pellicciari, Roberto ^b   Willson, Timothy M ^c   Khorasanizadeh, Sepideh ^a   Rastinejad, Fraydoon ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF PERUGIA   (Italy)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; FARNESOID X RECEPTOR; STEROID; UNCLASSIFIED DRUG;

ARTICLE; BINDING ASSAY; BINDING SITE; CHOLESTASIS; CRYSTAL STRUCTURE; HYPERLIPIDEMIA; LIGAND BINDING; PROTEIN CONFORMATION; PROTEIN MOTIF; RECEPTOR AFFINITY; X RAY CRYSTALLOGRAPHY;

EID: 0038752647     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(03)00112-6     Document Type: Article

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