Farnesoid X-activated receptor antagonists from a marine sponge Spongia sp.

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 20, 2006, Pages 5398-5402

  Nam, Sang Jip ^a   Ko, Hyunsil ^a   Shin, Mihee ^a   Ham, Jungyeob ^a   Chin, Jungwook ^a   Kim, Youngshin ^a   Kim, Heeyoung ^a   Shin, Kyoungjin ^a   Choi, Hyukjae ^a   Kang, Heonjoong ^a  

^a Seoul National University   (South Korea)

Author keywords

Farnesoid X activated receptor; Guggulsterone; Hypercholesterolemia; Marine sponge; Scalarane sesterterpene

Indexed keywords

FARNESOID X RECEPTOR; FARNESOID X RECEPTOR BLOCKING AGENT; GUGGULSTERONE; RECEPTOR BLOCKING AGENT; SCALARANE DERIVATIVE; SESTERTERPENE; UNCLASSIFIED DRUG;

ARTICLE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; DRUG TARGETING; HYPERCHOLESTEROLEMIA; NONHUMAN; RECEPTOR BLOCKING; SPONGE (PORIFERA); SPONGIA; STRUCTURE ANALYSIS; TRANSACTIVATION;

ANIMALS; CELL LINE; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; DNA-BINDING PROTEINS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PORIFERA; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REFERENCE STANDARDS; SESTERTERPENES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION;

SPONGIA;

EID: 33748302808     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.07.079     Document Type: Article

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