Review of pharmacological effects of antrodia camphorata and its bioactive compounds

Evidence-based Complementary and Alternative Medicine

Volumn 2011, Issue , 2011, Pages

  Tzeng, Yew Min ^a   Geethangili, Madamanchi ^a  

^a CHAOYANG UNIVERSITY OF TECHNOLOGY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIMETHOXY 2,3 METHYLENEDIOXY 5 METHYLBENZENE; 11,12 DIDEHYDRO 14 DEOXYANDROGRAPHOLIDE; 19 HYDROXYLABDA 8(17),13 DIEN 16,15 OLIDE; 2 METHOXY 5 METHYL(1,4)BENZOQUINONE; 2,3 DIMETHOXY 5 METHYL(1,4)BENZOQUINONE; 2,4 DIMETHOXY 6 METHYLBENZENE 1,3 DIOL; 2,4,5 TRIMETHOXYBENZALDEHYDE; 3 (4 HYDROXYPHENYL) 4 ISOBUTYL 1H PYRROLE 2,5 DIONE; 4 ACETYLANTROQUINONOL B; ANTCIN A; ANTCIN C; ANTROCAMPHIN A; ANTROCINNAMOMIN C; ANTRODIA CAMPHORATA EXTRACT; ANTRODIN D; ANTROQUINONOL; ANTROQUINONOL B; AROMATIC COMPOUND; BENZOQUINONE DERIVATIVE; CAMPHORATAIMIDE E; DEHYDROEBURICOIC ACID; DIMETHYL 2 (4 HYDROXYPHENYL) 3 ISOBUTYLMALEATE; LIGNAN DERIVATIVE; MALEIC ACID DERIVATIVE; METHYL ANTCINATE B; PLANT EXTRACT; SUCCINIC ACID DERIVATIVE; SULPHURENIC ACID; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ABDOMINAL PAIN; ANTIANGIOGENIC ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIVIRAL ACTIVITY; ANTRODIA CAMPHORATA; APOPTOSIS; CYTOKINE PRODUCTION; CYTOTOXICITY; DIABETES MELLITUS; DIARRHEA; ENZYME INHIBITION; HEPATITIS B VIRUS; HUMAN; HYPERTENSION; IC 50; IMMUNOMODULATION; INFLUENZA; LEUKEMIA CELL; LIPID PEROXIDATION; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER PROTECTION; METABOLIC SYNDROME X; MOTION SICKNESS; MUSCLE INJURY; NEPHRITIS; NEUROPROTECTION; NONHUMAN; PHYTOCHEMISTRY; PRIORITY JOURNAL; PROTEINURIA; PRURITUS; REVIEW; STOMATITIS; TRADITIONAL MEDICINE; VASODILATATION; VIRUS INFECTION; VIRUS REPLICATION;

EID: 79952231175     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nep108     Document Type: Review

References (110)

1. Zhang X., WHO Traditional Medicine Strategy 20022005 2002 Geneva, Switzerland World Health Organization
2. Tsao J. C. I., Zeltzer L. K., Complementary and alternative medicine approaches for pediatric pain: a review of the state-of-the-science Evidence-Based Complementary (Pubitemid 41399487)
3. Patwardhan B., Warude D., Pushpangadan P., Bhatt N., Ayurveda and traditional Chinese medicine: a comparative overview Evidence-Based Complementary and Alternative Medicine 2005 2 4 465 473 (Pubitemid 41752482)
4. Chang T. T., Chou W. N., Antrodia cinnamomea sp. nov. on Cinnamomum kanehirai in Taiwan Mycological Research 1995 99 6 756 758
5. Wu S.-H., Ryvarden L., Chang T.-T., Antrodia camphorata ('niu-chang-chih'), new combination of a medicinal fungus in Taiwan Botanical Bulletin of Academia Sinica 1997 38 4 273 275 (Pubitemid 27496370)
6. Chen J. C., Lin W. H., Chen C. N., Sheu S. J., Huang S. J., Chen Y. L., Development of Antrodia camphorata mycelium with submerged culture Fungal Sciences 2001 16 7 22
7. Tsai Z. T., Liaw S. L., The Use and the Effect of Ganoderma 1985 Taichung, Taiwan San Yun Press 116 17
8. Chen C. J., Su C. H., Lan M. H., Study on solid cultivation and bioactivity of Antrodia camphorata Fungal Sciences 2001 16 65 72
9. Zang M., Su Q. H., Ganoderma comphoratum, a new taxon in genus Ganoderma from Taiwan, China Acta Botanica Yunnanica 1990 12 395 396
10. Chang T.-T., Chou W.-N., Antrodia cinnamomea reconsidered and A. salmonea sp. nov. on Cunninghamia konishii in Taiwan Botanical Bulletin of Academia Sinica 2004 45 4 347 352 (Pubitemid 39547720)
11. Wu S. H., Yu Z. H., Dai Y. C., Taiwanofungus, a polypore new genus Fungal Sciences 2004 19 109 116
12. Chiu H.-H., Phylogenetic analysis of Antrodia species and Antrodia camphorata inferred from internal transcribed spacer region Antonie van Leeuwenhoek 2007 91 3 267 276 (Pubitemid 46431842)
13. Hawksworth D. L., Kirk P. M., Sutton B. C., Pegler D. N., Ainsworth and Bisby's Dictionary of the Fungi 1995 8th Egham, UK International Mycological Institute
14. Su C. H., Health Guardian Angel: Antrodia camphorata 2002 1st Taipei, Taiwan EKS Book Publishing
15. Chen J. C., King of Ganoderma: Antrodia camphorata in Taiwan 2008 2nd Taipei, Taiwan Yuen Chi Jai Book Publishing
16. Cheng J.-J., Yang C.-J., Cheng C.-H., Wang Y.-T., Huang N.-K., Lu M.-K., Characterization and functional study of Antrodia camphorata lipopolysaccharide Journal of Agricultural and Food Chemistry 2005 53 2 469 474 (Pubitemid 40129943)
17. Cherng I.-H., Chiang H.-C., Cheng M.-C., Wang Y. U., Three new triterpenoids from Antrodia cinnamomea Journal of Natural Products 1995 58 3 365 371
18. Chen C.-H., Yang S.-W., Shen Y.-C., New steroid acids from Antrodia cinnamomea, a fungal parasite of Cinnamomum micranthum Journal of Natural Products 1995 58 11 1655 1661 (Pubitemid 26051586)
19. Chiang C. H., Wu D. P., Cherng I. W., Ueng U. C., A sesquiterpene lactone, phenyl and biphenyl compounds from Antrodia cinnamomea Phytochemistry 1995 39 3 613 616
20. Wu D. P., Chiang C. H., Constituents of Antrodia cinnamomea Journal of the Chinese Chemical Society 1995 42 797 800
21. Cherng I.-H., Wu D.-P., Chiang H.-C., Triterpenoids from Antrodia cinnamomea Phytochemistry 1996 41 1 263 267 (Pubitemid 126685894)
22. Yang S.-W., Shen Y.-C., Chen C.-H., Steroids and triterpenoids of Antrodia cinnamomea a fungus parasitic on Cinnamomum micranthum Phytochemistry 1996 41 5 1389 1392 (Pubitemid 126686098)
23. Shen Y.-C., Yang S.-W., Lin C.-S., Chen C.-H., Kuo Y.-H., Chen C.-F., Zhankuic acid F: a new metabolite from a formosan fungus Antrodia cinnamomea Planta Medica 1997 63 1 86 88 (Pubitemid 27112450)
24. Huang K.-F., Huang W.-M., Chiang H.-C., Phenyl compounds from Antrodia cinnamomea Chinese Pharmaceutical Journal 2001 53 6 327 331 (Pubitemid 33761113)
25. Shen C. C., Kuo Y. C., Huang R. L., New ergostane and lanostane from Antrodia camphorata The Journal of Chinese Medicine 2003 14 247 58
26. Nakamura N., Hirakawa A., Gao J.-J., Kakuda H., Shiro M., Komatsu Y., Sheu C.-C., Hattori M., Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line Journal of Natural Products 2004 67 1 46 48 (Pubitemid 38141309)
27. Shen C. C., Yang H. C., Huang R. L., Chen J. C., Chen C. C., Anti-HBV principle from the culture broth of Antrodia camphorata (strain # CCRC-35396) The Journal of Chinese Medicine 2005 16 57 61
28. Chen C.-C., Shiao Y.-J., Lin R.-D., Shao Y.-Y., Lai M.-N., Lin C.-C., Ng L.-T., Kuo Y.-H., Neuroprotective diterpenes from the fruiting body of Antrodia camphorata Journal of Natural Products 2006 69 4 689 691 (Pubitemid 43798130)
29. Hattori M., Sheu C. C., Compounds from Antrodia camphorata having anti-inflammatory and anti-tumor activity. US 7109232-2006-9-19, 2006
30. Chen J.-J., Lin W.-J., Liao C.-H., Shieh P.-C., Anti-inflammatory benzenoids from Antrodia camphorata Journal of Natural Products 2007 70 6 989 992 (Pubitemid 47056115)
31. Chen C.-C., Chyau C.-C., Hseu T.-H., Production of a COX-2 inhibitor, 2,4,5-trimethoxybenzaldehyde, with submerged cultured Antrodia camphorata Letters in Applied Microbiology 2007 44 4 387 392 (Pubitemid 46496373)
32. Lee T.-H., Lee C.-K., Tsou W.-L., Liu S.-Y., Kuo M.-T., Wen W.-C., A new cytotoxic agent from solid-state fermented mycelium of Antrodia camphorata Planta Medica 2007 73 13 1412 1415 (Pubitemid 350084463)
33. Chien S.-C., Chen M.-L., Kuo H.-T., Tsai Y.-C., Lin B.-F., Kuo Y.-H., Anti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata Journal of Agricultural and Food Chemistry 2008 56 16 7017 7022
34. Wu M.-D., Cheng M.-J., Wang B.-C., Wang W.-Y., Lai J.-T., Yuan G.-F., Chemical constituents from the mycelia of Antrodia cinnamomea Journal of the Chilean Chemical Society 2007 52 4 1338 1340
35. Wu M.-D., Cheng M.-J., Wang B.-C., Yech Y.-J., Lai J.-T., Kuo Y.-H., Yuan G.-F., Chen I.-S., Maleimide and maleic anhydride derivatives from the mycelia of Antrodia cinnamomea and their nitric oxide inhibitory activities in macrophages Journal of Natural Products 2008 71 7 1258 1261
36. Yang S.-S., Wang G.-J., Wang S.-Y., Lin Y.-Y., Kuo Y.-H., Lee T.-H., New constituents with iNOS inhibitory activity from mycelium of Antrodia camphorata Planta Medica 2009 75 5 512 516
37. Lu M.-K., Cheng J.-J., Lai W.-L., Lin Y.-R., Huang N.-K., Adenosine as an active component of Antrodia cinnamomea that prevents rat PC12 cells from serum deprivation-induced apoptosis through the activation of adenosine A2A receptors Life Sciences 2006 79 3 252 258 (Pubitemid 43796205)
38. Lee I.-H., Huang R.-L., Chen C.-T., Chen H.-C., Hsu W.-C., Lu M.-K., Antrodia camphorata polysaccharides exhibit anti-hepatitis B virus effects FEMS Microbiology Letters 2002 209 1 63 67 (Pubitemid 34457983)
39. Chen S. C., Lu M. K., Cheng J. J., Wang D. L., Antiangiogenic activities of polysaccharides isolated from medicinal fungi FEMS Microbiology Letters 2005 249 2 247 254
40. Chen C.-C., Liu Y.-W., Ker Y.-B., Wu Y.-Y., Lai E. Y., Chyau C.-C., Hseu T.-H., Peng R. Y., Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia Journal of Agricultural and Food Chemistry 2007 55 13 5007 5012 (Pubitemid 47056049)
41. Mahajna J., Dotan N., Zaidman B.-Z., Petrova R. D., Wasser S. P., Pharmacological values of medicinal mushrooms for prostate cancer therapy: the case of Ganoderma lucidum Nutrition and Cancer 2009 61 1 16 26
42. Lindequist U., Niedermeyer T. H. J., Jlich W.-D., The pharmacological potential of mushrooms Evidence-Based Complementary and Alternative Medicine 2005 2 3 285 299 (Pubitemid 41258148)
43. Hsu Y.-L., Kuo Y.-C., Kuo P.-L., Ng L.-T., Kuo Y.-H., Lin C.-C., Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines Cancer Letters 2005 221 1 77 89 (Pubitemid 40387911)
44. Kuo P.-L., Hsu Y.-L., Cho C.-Y., Ng L.-T., Kuo Y.-H., Lin C.-C., Apoptotic effects of Antrodia cinnamomea fruiting bodies extract are mediated through calcium and calpain-dependent pathways in Hep 3B cells Food and Chemical Toxicology 2006 44 8 1316 1326
45. Hsu Y.-L., Kuo P.-L., Cho C.-Y., Ni W.-C., Tzeng T.-F., Ng L.-T., Kuo Y.-H., Lin C.-C., Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor B pathway Food and Chemical Toxicology 2007 45 7 1249 1257 (Pubitemid 46590565)
46. Rao Y. K., Fang S.-H., Tzeng Y.-M., Evaluation of the anti-inflammatory and anti-proliferation tumoral cells activities of Antrodia camphorata, Cordyceps sinensis, and Cinnamomum osmophloeum bark extracts Journal of Ethnopharmacology 2007 114 1 78 85 (Pubitemid 47444512)
47. Chang C.-Y., Huang Z.-N., Yu H.-H., Chang L.-H., Li S.-L., Chen Y.-P., Lee K.-Y., Chuu J.-J., The adjuvant effects of Antrodia camphorata extracts combined with anti-tumor agents on multidrug resistant human hepatoma cells Journal of Ethnopharmacology 2008 118 3 387 395
48. Lu M.-C., Du Y.-C., Chuu J.-J., Hwang S.-L., Hsieh P.-C., Hung C.-S., Chang F.-R., Wu Y.-C., Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A Archives of Toxicology 2009 83 2 121 129
49. Hseu Y.-C., Chang W.-C., Hseu Y.-T., Lee C.-Y., Yech Y.-J., Chen P.-C., Chen J.-Y., Yang H.-L., Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes Life Sciences 2002 71 4 469 482 (Pubitemid 34607308)
50. Hseu Y.-C., Yang H.-L., Lai Y.-C., Lin J.-G., Chen G.-W., Chang Y.-H., Induction of apoptosis by Antrodia camphorata in human premyelocytic leukemia HL-60 cells Nutrition and Cancer 2004 48 2 189 197 (Pubitemid 39045781)
51. Wu H., Pan C.-L., Yao Y.-C., Chang S.-S., Li S.-L., Wu T.-F., Proteomic analysis of the effect of Antrodia camphorata extract on human lung cancer A549 cell Proteomics 2006 6 3 826 835 (Pubitemid 43260208)
52. Song T.-Y., Hsu S.-L., Yen G.-C., Induction of apoptosis in human hepatoma cells by mycelia of Antrodia camphorata in submerged culture Journal of Ethnopharmacology 2005 100 1-2 158 167 (Pubitemid 41073540)
53. Song T. Y., Hsu S. L., Yeh C. T., Yen G. C., Mycelia from Antrodia camphorata in submerged culture induced apoptosis of human heptoma Hep G2 cells possibility through regulation of Fas pathway Journal of Agricultural and Food Chemistry 2005 53 5559 5564
54. Chen Y.-S., Pan J.-H., Chiang B.-H., Lu F.-J., Sheen L.-Y., Ethanolic extracts of Antrodia cinnamomea mycelia fermented at varied times and scales have differential effects on hepatoma cells and normal primary hepatocytes Journal of Food Science 2008 73 7 H179 H185
55. Yang H.-L., Chen C.-S., Chang W.-H., Lu F.-J., Lai Y.-C., Chen C.-C., Hseu T.-H., Kuo C.-T., Hseu Y.-C., Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by Antrodia camphorata Cancer Letters 2006 231 2 215 227 (Pubitemid 43038732)
56. Hseu Y.-C., Chen S.-C., Tsai P.-C., Chen C.-S., Lu F.-J., Chang N.-W., Yang H.-L., Inhibition of cyclooxygenase-2 and induction of apoptosis in estrogen-nonresponsive breast cancer cells by Antrodia camphorata Food and Chemical Toxicology 2007 45 7 1107 1115 (Pubitemid 46590552)
57. Hseu Y.-C., Chen S.-C., Chen H.-C., Liao J.-W., Yang H.-L., Antrodia camphorata inhibits proliferation of human breast cancer cells in vitro and in vivo Food and Chemical Toxicology 2008 46 8 2680 2688
58. Peng C.-C., Chen K.-C., Peng R. Y., Su C.-H., Hsieh-Li H. M., Human urinary bladder cancer T24 cells are susceptible to the Antrodia camphorata extracts Cancer Letters 2006 243 1 109 119 (Pubitemid 44485321)
59. Peng C.-C., Chen K.-C., Peng R. Y., Chyau C.-C., Su C.-H., Hsieh-Li H. M., Antrodia camphorata extract induces replicative senescence in superficial TCC, and inhibits the absolute migration capability in invasive bladder carcinoma cells Journal of Ethnopharmacology 2007 109 1 93 103 (Pubitemid 44920191)
60. Chen K.-C., Peng C.-C., Peng R. Y., Su C.-H., Chiang H.-S., Yan J.-H., Hsieh-Li H. M., Unique formosan mushroom Antrodia camphorata differentially inhibits androgen-responsive LNCaP and -independent PC-3 prostate cancer cells Nutrition and Cancer 2007 57 1 111 121 (Pubitemid 46871575)
61. Lu M.-K., Cheng J.-J., Lai W.-L., Lin Y.-J., Huang N.-K., Fermented Antrodia cinnamomea extract protects rat PC12 cells from serum deprivation-induced apoptosis: the role of the MAPK family Journal of Agricultural and Food Chemistry 2008 56 3 865 874 (Pubitemid 351300257)
62. Ho C.-M., Huang C.-C., Huang C.-J., Cheng J.-S., Chen I.-S., Tsai J.-Y., Jiann B.-P., Tseng P.-L., Kuo S.-J., Jan C.-R., Effects of Antrodia camphorata on viability, apoptosis, and [ Ca2+ ]i in PC3 human prostate cancer cells Chinese Journal of Physiology 2008 51 2 78 84
63. Lu Y.-C., Huang C.-C., Huang C.-J., Chu S.-T., Chi C.-C., Su H.-H., Hsu S.-S., Wang J.-L., Chen I.-S., Liu S.-I., Huang J.-K., Ho C.-M., Kuo S.-J., Jan C.-R., Effects of Antrodia camphorata on viability, apoptosis, [ Ca2+ ]i, and MAPKs phosphorylation in MG63 human osteosarcoma cells Drug Development Research 2007 68 2 71 78 (Pubitemid 47205960)
64. Male K. B., Rao Y. K., Tzeng Y.-M., Montes J., Kamen A., Luong J. H. T., Probing inhibitory effects of Antrodia camphorata isolates using insect cell-based impedance spectroscopy: inhibition vs chemical structure Chemical Research in Toxicology 2008 21 11 2127 2133
65. Yeh C. T., Rao Y. K., Yeh C. F., Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells Cancer Letters 2009 285 1 73 79
66. Shen Y.-C., Wang Y.-H., Chou Y.-C., Chen C.-F., Lin L.-C., Chang T.-T., Tien J.-H., Chou C.-J., Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata Planta Medica 2004 70 4 310 314 (Pubitemid 38594601)
67. Shen Y.-C., Chen C.-F., Wang Y.-H., Chang T.-T., Chou C.-J., Evaluation of the immuno-modulating activity of some active principles isolated from the fruiting bodies of Antrodia camphorata Chinese Pharmaceutical Journal 2003 55 5 313 318 (Pubitemid 38901927)
68. Lien H. M., Lin H. W., Wang Y. J., Inhibition of anchorage-independent proliferation and G0/G1 cell-cycle regulation in human colorectal carcinoma cells by 4,7-dimethoxy-5-methyl-l,3-benzodioxole isolated from the fruiting body of Antrodia camphorata Evidence-Based Complementary and Alternative Medicine 2009
69. Phuong D. T., Ma C.-M., Hattori M., Jin J. S., Short communication: inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis c virus protease Phytotherapy Research 2009 23 4 582 584
70. Chen Y.-J., Cheng P.-C., Lin C.-N., Liao H.-F., Chen Y.-Y., Chen C.-C., Lee K.-M., Polysaccharides from Antrodia camphorata mycelia extracts possess immunomodulatory activity and inhibits infection of Schistosoma mansoni International Immunopharmacology 2008 8 3 458 467
71. Huang R.-L., Huang Q., Chen C.-F., Chang T.-T., Chou C.-J., Anti-viral effects of active compounds from Antrodia camphorata on wild-type and lamivudine-resistant mutant HBV Chinese Pharmaceutical Journal 2003 55 5 371 379 (Pubitemid 38901933)
72. Chang J. M., Lee Y. R., Hung L. M., An extract of Antrodia camphorata mycelia attenuates the progression of nephritis in systemic lupus erythematosus-prone NZB/W F1 mice Evidence-Based Complementary and Alternative Medicine 2008
73. Aydemir G., Research on nutrition and cancer: the importance of the standardized dietary assessments Asian Pacific Journal of Cancer Prevention 2002 3 177 180
74. Haddad P. S., Azar G. A., Groom S., Boivin M., Natural health products, modulation of immune function and prevention of chronic diseases Evidence-Based Complementary and Alternative Medicine 2005 2 4 513 520 (Pubitemid 41752488)
75. Vojdani A., Erde J., Regulatory T cells, a potent immunoregulatory target for CAM researchers: modulating tumor immunity, autoimmunity and alloreactive immunity (III) Evidence-Based Complementary and Alternative Medicine 2006 3 3 309 316 (Pubitemid 44310274)
76. Kaminogawa S., Nanno M., Modulation of immune functions by foods Evidence-Based Complementary and Alternative Medicine 2005 1 241 250
77. Shen Y.-C., Chou C.-J., Wang Y.-H., Chen C.-F., Chou Y.-C., Lu M.-K., Anti-inflammatory activity of the extracts from mycelia of Antrodia camphorata cultured with water-soluble fractions from five different Cinnamomum species FEMS Microbiology Letters 2004 231 1 137 143 (Pubitemid 38177603)
78. Hseu Y.-C., Wu F.-Y., Wu J.-J., Chen J.-Y., Chang W.-H., Lu F.-J., Lai Y.-C., Yang H.-L., Anti-inflammatory potential of Antrodia camphorata through inhibition of iNOS, COX-2 and cytokines via the NF- B pathway International Immunopharmacology 2005 5 13-14 1914 1925 (Pubitemid 41586230)
79. Liu D.-Z., Liang H.-J., Chen C.-H., Su C.-H., Lee T.-H., Huang C.-T., Hou W.-C., Lin S.-Y., Zhong W.-B., Lin P.-J., Hung L.-F., Liang Y.-C., Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action Journal of Ethnopharmacology 2007 113 1 45 53 (Pubitemid 47077849)
80. Kuo M.-C., Chang C.-Y., Cheng T.-L., Wu M.-J., Immunomodulatory effect of Antrodia camphorata mycelia and culture filtrate Journal of Ethnopharmacology 2008 120 2 196 203
81. Chen J. C., Chen C. N., Sheu S. J., Liver-caring medicine containing Antrodia camphorate. US 0113297-2003-6-19, 2003
82. Song T.-Y., Yen G.-C., Antioxidant properties of Antrodia camphorata in submerged culture Journal of Agricultural and Food Chemistry 2002 50 11 3322 3327 (Pubitemid 34533641)
83. Hsiao G., Shen M.-Y., Lin K.-H., Lan M.-H., Wu L.-Y., Chou D.-S., Lin C.-H., Su C.-H., Sheu J.-R., Antioxidative and hepatoprotective effects of Antrodia camphorata extract Journal of Agricultural and Food Chemistry 2003 51 11 3302 3308
84. Mau J.-L., Huang P.-N., Huang S.-J., Chen C.-C., Antioxidant properties of methanolic extracts from two kinds of Antrodia camphorata mycelia Food Chemistry 2004 86 1 25 31 (Pubitemid 38199883)
85. Shu C.-H., Lung M.-Y., Effect of culture pH on the antioxidant properties of Antrodia camphorata in submerged culture Journal of the Chinese Institute of Chemical Engineers 2008 39 1 1 8
86. Yang H.-L., Hseu Y.-C., Chen J.-Y., Yech Y.-J., Lu F.-J., Wang H.-H., Lin P.-S., Wang B.-C., Antrodia camphorata in submerged culture protects low density lipoproteins against oxidative modification American Journal of Chinese Medicine 2006 34 2 217 231
87. Hseu Y.-C., Chen S.-C., Yech Y.-J., Wang L., Yang H.-L., Antioxidant activity of Antrodia camphorata on free radical-induced endothelial cell damage Journal of Ethnopharmacology 2008 118 2 237 245
88. Huang S.-J., Mau J.-L., Antioxidant properties of methanolic extracts from Antrodia camphorata with various doses of -irradiation Food Chemistry 2007 105 4 1702 1710 (Pubitemid 47095146)
89. Ao Z.-H., Xu Z.-H., Lu Z.-M., Xu H.-Y., Zhang X.-M., Dou W.-F., Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases Journal of Ethnopharmacology 2009 121 2 194 212
90. Dai Y.-Y., Chuang C.-H., Tsai C.-C., Sio H.-M., Huang S.-C., Chen J.-C., Hu M.-L., The protection of Anthrodia camphorata against acute hepatotoxicity of alcohol in rats Journal of Food and Drug Analysis 2003 11 3 177 185 (Pubitemid 37428453)
91. Lu Z.-M., Tao W.-Y., Zou X.-L., Fu H.-Z., Ao Z.-H., Protective effects of mycelia of Antrodia camphorata and Armillariella tabescens in submerged culture against ethanol-induced hepatic toxicity in rats Journal of Ethnopharmacology 2007 110 1 160 164 (Pubitemid 46209574)
92. Song T.-Y., Yen G.-C., Protective effects of fermented filtrate from Antrodia camphorata in submerged culture against CCl4-induced hepatic toxicity in rats Journal of Agricultural and Food Chemistry 2003 51 6 1571 1577
93. Huang J. S., Chang H. C., Li E. I. C., Huang T. M., Su Y. H., Wang K. C., Enhancement of hepatoprotective efficacy of Antrodia camphorata by Chinese tradition medicine Journal of Gastroenterology and Hepatology 2006 21 supplement 2 A234
94. Lin W.-C., Kuo S.-C., Lin W.-L., Fang H.-L., Wang B.-C., Filtrate of fermented mycelia from Antrodia camphorata reduces liver fibrosis induced by carbon tetrachloride in rats World Journal of Gastroenterology 2006 12 15 2369 2374
95. Guo S. Q., Ameliorative effects of Antrodia camphorata on liver fibrosis and gastrointestinal functions in rats, M.S. thesis 2002 Taiwan China Medical College
96. Huang N.-K., Cheng J.-J., Lai W.-L., Lu M.-K., Antrodia camphorata prevents rat pheochromocytoma cells from serum deprivation-induced apoptosis FEMS Microbiology Letters 2005 244 1 213 219 (Pubitemid 40261199)
97. Liu D.-Z., Liang Y.-C., Lin S.-Y., Lin Y.-S., Wu W.-C., Hou W.-C., Su C.-H., Antihypertensive activities of a solid-state culture of Taiwanofungus camphoratus (Chang-Chih) in spontaneously hypertensive rats Bioscience, Biotechnology and Biochemistry 2007 71 1 23 30 (Pubitemid 46156865)
98. Wang G.-J., Tseng H.-W., Chou C.-J., Tsai T.-H., Chen C.-T., Lu M.-K., The vasorelaxation of Antrodia camphorata mycelia: involvement of endothelial Ca2+ -NO-cGMP pathway Life Sciences 2003 73 21 2769 2783 (Pubitemid 37123123)
99. Geethangili M., Fang S. H., Lai C. H., Rao Y. K., Lien H. M., Tzeng Y. M., Inhibitory effect of Antrodia camphorata constituents on the Helicobacter pylori- associated gastric inflammation Food Chemistry 2010 119 1 149 153
100. Schepetkin I. A., Quinn M. T., Botanical polysaccharides: macrophage immunomodulation and therapeutic potential International Immunopharmacology 2006 6 3 317 333 (Pubitemid 43120446)
101. Liu J.-J., Huang T.-S., Hsu M.-L., Chen C.-C., Lin W.-S., Lu F.-J., Chang W.-H., Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action Toxicology and Applied Pharmacology 2004 201 2 186 193 (Pubitemid 39487165)
102. Cheng J.-J., Huang N.-K., Chang T.-T., Wang D. L., Lu M.-K., Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells Life Sciences 2005 76 26 3029 3042 (Pubitemid 40585705)
103. Han H.-F., Nakamura N., Zuo F., Hirakawa A., Yokozawa T., Hattori M., Protective effects of a neutral polysaccharide isolated from the mycelium of Antrodia cinnamomea on Propionibacterium acnes and lipopolysaccharide induced hepatic injury in mice Chemical and Pharmaceutical Bulletin 2006 54 4 496 500
104. Wu Y.-Y., Chen C.-C., Chyau C.-C., Chung S.-Y., Liu Y.-W., Modulation of inflammation-related genes of polysaccharides fractionated from mycelia of medicinal basidiomycete Antrodia camphorata Acta Pharmacologica Sinica 2007 28 2 258 267 (Pubitemid 46155544)
105. Cheng P.-C., Hsu C.-Y., Chen C.-C., Lee K.-M., In vivo immunomodulatory effects of Antrodia camphorata polysaccharides in a T1/T2 doubly transgenic mouse model for inhibiting infection of Schistosoma mansoni Toxicology and Applied Pharmacology 2008 227 2 291 298
106. Tsai M.-C., Song T.-Y., Shih P.-H., Yen G.-C., Antioxidant properties of water-soluble polysaccharides from Antrodia cinnamomea in submerged culture Food Chemistry 2007 104 3 1115 1122 (Pubitemid 46779024)
107. Cheng J.-J., Huang N.-K., Lur H.-S., Kuo C.-I., Lu M.-K., Characterization and biological functions of sulfated polysaccharides from sulfated-salt treatment of Antrodia cinnamomea Process Biochemistry 2009 44 4 453 459
108. Liu S. Y., Kuo M. T., Wen W. C., Inhibition of hepatitis B virus by cyclohexenone compounds from Antrodia camphorata. US US 7411003, 2009
109. Paterson R. R. M., Ganodermaa therapeutic fungal biofactory Phytochemistry 2006 67 18 1985 2001
110. Majid E., Male K. B., Tzeng Y.-M., Omamogho J. O., Glennon J. D., Luong J. H. T., Cyclodextrin-modified capillary electrophoresis for achiral and chiral separation of ergostane and lanostane compounds extracted from the fruiting body of Antrodia camphorata Electrophoresis 2009 30 11 1967 197