A new cytotoxic agent from solid-state fermented mycelium of Antrodia camphorata

Planta Medica

Volumn 73, Issue 13, 2007, Pages 1412-1415

  Lee, Tzong Huei ^a   Lee, Ching Kuo ^a   Tsou, Wan Lin ^b   Liu, Sheng Yung ^b   Kuo, Mao Tien ^b   Wen, Wu Che ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b GOLDEN BIOTECHNOLOGY CORPORATION   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTROQUINONOL; UBIQUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTRODIA CAMPHORATA; APHYLLOPHORALES; ARTICLE; BREAST CARCINOMA; CELL LINE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; FUNGUS; HUMAN; HUMAN CELL; LIVER CARCINOMA; MYCELIUM; PARASITE; POLYPORACEAE; PROSTATE CARCINOMA; SOLID STATE FERMENTATION; SPECTROSCOPY; TAIWAN;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; FERMENTATION; HUMANS; INHIBITORY CONCENTRATION 50; MYCELIUM; PHYTOTHERAPY; PLANT EXTRACTS; POLYPORALES;

APHYLLOPHORALES; FUNGI; POLYPORACEAE; TAIWANOFUNGUS CAMPHORATUS;

EID: 36049033448     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-990232     Document Type: Article

References (10)

1. Wu SH, Ryvarden L, Chang TT. Antrodia camphorata ("niu-changchih"), new combination of a medicinal fungus in Taiwan. Bot Bull Acad Sin 1997; 38: 273-5.
2. Chen CC, Shiao YJ, Lin RD, Shao YY, Lai MN, Lin CC et al. Neuroprotective diterpenes from the fruiting body of Antrodia camphorata. 2006; 69: 689-91.
3. Shen YC, Chou CJ, Wang YH, Chen CF, Chou YC, Lu MK. Anti-inflammatory activity of the extracts from mycelia of Antrodia camphorata cultured with water-soluble fractions from five different Cinnamomum species. FEMS Microbiol Lett 2004; 231: 137-43.
4. Wang GJ, Tseng HW, Chou CJ, Tsai TH, Chen CT, Lu MK. The vasorelaxation of Antrodia camphorata mycelia: involvement of endothelial Ca(2+)-NO-cGMP pathway. 2003; 73: 2769-83.
5. Liu JJ, Huang TS, Hsu ML, Chen CC, Lin WS, Lu FJ et al. Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action. Toxicol Appl Pharmacol 2004; 201: 186-93.
6. Hseu YC, Chang WC, Hseu YT, Lee CY, Yech YJ, Chen PC et al. Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes. Life Sci 2002; 71: 469-82.
7. Lee IH, Huang RL, Chen CT, Chen HC, Hsu WC, Lu MK. Antrodia camphorata polysaccharides exhibit anti-hepatitis B virus effects. FEMS Microbiol Lett 2002; 209: 63-7.
8. Nakamura N, Hirakawa A, Gao JJ, Kakuda H, Shiro M, Komatsu Y et al. Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line. J Nat Prod 2004; 67: 46-8.
9. Joela H, Kasa S, Lehtovuori P, Bech M. EPR, ENDOR and TRIPLE resonance and MO studies on ubiquinones (Q-n): comparison of radical anions and cations of coenzymes Q-10 and Q-6 with the model compounds Q-2 and Q-0. Acta Chem Scand 1997; 51: 233-41.
10. Hansen MB, Nielsen SE, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 1989; 119: 203-10.